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Corey–Fuchs reaction

Index Corey–Fuchs reaction

The Corey–Fuchs reaction, also known as the Ramirez–Corey–Fuchs reaction, is a series of chemical reactions designed to transform an aldehyde into an alkyne. [1]

16 relations: Aldehyde, Alkyne, Appel reaction, Carbene, Chemical reaction, Dichlorocarbene, Elias James Corey, Fritsch–Buttenberg–Wiechell rearrangement, Journal of the American Chemical Society, Organic Syntheses, Seyferth–Gilbert homologation, Tetrabromomethane, Tetrahedron Letters, Triphenylphosphine, Wittig reaction, Ylide.

Aldehyde

An aldehyde or alkanal is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain.

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Alkyne

In organic chemistry, an alkyne is an unsaturated hydrocarbon containing at least one carbon—carbon triple bond.

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Appel reaction

The Appel reaction is an organic reaction that converts an alcohol into an alkyl chloride using triphenylphosphine and carbon tetrachloride.

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Carbene

In chemistry, a carbene is a molecule containing a neutral carbon atom with a valence of two and two unshared valence electrons.

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Chemical reaction

A chemical reaction is a process that leads to the transformation of one set of chemical substances to another.

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Dichlorocarbene

Dichlorocarbene is the reactive intermediate with chemical formula CCl2.

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Elias James Corey

Elias James "E.J." Corey (born July 12, 1928) is an American organic chemist.

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Fritsch–Buttenberg–Wiechell rearrangement

The Fritsch–Buttenberg–Wiechell rearrangement, named for Paul Ernst Moritz Fritsch (1859–1913), Wilhelm Paul Buttenberg, and Heinrich G. Wiechell, is a chemical reaction whereby a 1,1-diaryl-2-bromo-alkene rearranges to a 1,2-diaryl-alkyne by reaction with a strong base such as an alkoxide.

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Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

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Organic Syntheses

Organic Syntheses is a peer-reviewed scientific journal that was established in 1921.

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Seyferth–Gilbert homologation

The Seyferth–Gilbert homologation is a chemical reaction of an aryl ketone 1 (or aldehyde) with dimethyl (diazomethyl)phosphonate 2 and potassium tert-butoxide to give substituted alkynes 3.

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Tetrabromomethane

Tetrabromomethane, CBr4, also known as carbon tetrabromide, is a carbon bromide.

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Tetrahedron Letters

Tetrahedron Letters is a weekly international journal for rapid publication of full original research papers in the field of organic chemistry.

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Triphenylphosphine

Triphenylphosphine (IUPAC name: triphenylphosphane) is a common organophosphorus compound with the formula P(C6H5)3 - often abbreviated to PPh3 or Ph3P.

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Wittig reaction

The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with a triphenyl phosphonium ylide (often called a Wittig reagent) to give an alkene and triphenylphosphine oxide.

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Ylide

A ylide or ylid is a neutral dipolar molecule containing a formally negatively charged atom (usually a carbanion) directly attached to a heteroatom with a formal positive charge (usually nitrogen, phosphorus or sulfur), and in which both atoms have full octets of electrons.

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Corey-Fuchs Reaction, Corey-Fuchs reaction.

References

[1] https://en.wikipedia.org/wiki/Corey–Fuchs_reaction

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