Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Install
Faster access than browser!
 

Demethylation and Sertraline

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Demethylation and Sertraline

Demethylation vs. Sertraline

Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule. Sertraline, sold under the trade names Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Similarities between Demethylation and Sertraline

Demethylation and Sertraline have 4 things in common (in Unionpedia): Cytochrome P450, Desipramine, Paroxetine, Substrate (chemistry).

Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

Cytochrome P450 and Demethylation · Cytochrome P450 and Sertraline · See more »

Desipramine

Desipramine, sold under the brand name Norpramin and Pertofrane among others, is a tricyclic antidepressant (TCA) which is used in the treatment of depression.

Demethylation and Desipramine · Desipramine and Sertraline · See more »

Paroxetine

Paroxetine, also known by trade names including Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, social anxiety disorder, panic disorder, posttraumatic stress disorder, generalized anxiety disorder and premenstrual dysphoric disorder. It has also been used in the treatment of hot flashes and night sweats associated with menopause. It has a similar tolerability profile to other SSRIs. The common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping and delayed ejaculation. It may also be associated with a slightly increased risk of birth defects. The rate of withdrawal symptoms in young people may be higher with paroxetine and venlafaxine than other SSRIs and SNRIs. Several studies have associated paroxetine with suicidal thinking and behavior in children and adolescents. Marketing of the drug began in 1992 by the pharmaceutical company SmithKline Beecham, known since 2000 as GlaxoSmithKline. Generic formulations have been available since 2003 when the patent expired. The United States Department of Justice fined GlaxoSmithKline $3 billion in 2012, including a sum for withholding data on paroxetine, unlawfully promoting it for under-18s and preparing an article, following one of its clinical trials, study 329, that misleadingly reported the drug was effective in treating adolescent depression.

Demethylation and Paroxetine · Paroxetine and Sertraline · See more »

Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

Demethylation and Substrate (chemistry) · Sertraline and Substrate (chemistry) · See more »

The list above answers the following questions

Demethylation and Sertraline Comparison

Demethylation has 27 relations, while Sertraline has 191. As they have in common 4, the Jaccard index is 1.83% = 4 / (27 + 191).

References

This article shows the relationship between Demethylation and Sertraline. To access each article from which the information was extracted, please visit:

Hey! We are on Facebook now! »