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21 relations: Biomarker, Central nervous system, Cyclooxygenase, Cytochrome P450, Docosahexaenoic acid, Docosatetraenoic acid, Epoxyeicosatrienoic acid, Inflammation, Innate immune system, Isomer, Ketone, Lipid signaling, Lipoxygenase, Maresin, Neurofuran, Neuroprotectin, Omega-3 fatty acid, Oxidative stress, Polyunsaturated fatty acid, Resolvin, Specialized pro-resolving mediators.
Biomarker
A biomarker, or biological marker, generally refers to a measurable indicator of some biological state or condition.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cyclooxygenase
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid.
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Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
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Docosahexaenoic acid
Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina.
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Docosatetraenoic acid
Docosatetraenoic acid designates any straight chain 22:4 fatty acid.
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Epoxyeicosatrienoic acid
The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Innate immune system
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
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Isomer
An isomer (from Greek ἰσομερής, isomerès; isos.
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Ketone
In chemistry, a ketone (alkanone) is an organic compound with the structure RC(.
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Lipid signaling
Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses.
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Lipoxygenase
Lipoxygenases are a family of (non-heme), iron-containing enzymes most of which catalyze the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene into cell signaling agents that serve diverse roles as autocrine signals that regulate the function of their parent cells, paracrine signals that regulate the function of nearby cells, and endocrine signals that regulate the function of distant cells.
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Maresin
Maresin 1 (MaR1 or 7R,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid) is a macrophage-derived mediator of inflammation resolution coined from macrophage mediator in resolving inflammation.
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Neurofuran
Neurofurans are 22-carbon compounds formed nonenzymatically by free radical mediated peroxidation of docosahexaenoic acid (DHA), an ω-3 essential fatty acid.
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Neuroprotectin
Neuroprotectin D1 (NPD1) (10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid) also known as Protectin D1 (PD1) is a docosanoid derived from the polyunsaturated fatty acid (PUFA) docosahexaenoic acid (DHA), which is a component of fish oil and the most important omega-3 PUFA.
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Omega-3 fatty acid
Omega−3 fatty acids, also called ω−3 fatty acids or n−3 fatty acids, are polyunsaturated fatty acids (PUFAs).
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Oxidative stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.
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Polyunsaturated fatty acid
Polyunsaturated fatty acids (PUFAs) are fatty acids that contain more than one double bond in their backbone.
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Resolvin
Resolvins are metabolic byproducts of omega-3 fatty acids, primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as well as docosapentaenoic acid (DPA) and clupanodonic acid.
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Specialized pro-resolving mediators
Specialized pro-resolving mediators (SPM, also termed specialized proresolving mediators) are a large and growing class of cell signaling molecules formed in cells by the metabolism of polyunsaturated fatty acids (PUFA) by one or a combination of lipoxygenase, cyclooxygenase, and cytochrome P450 monooxygenase enzymes.
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References
[1] https://en.wikipedia.org/wiki/Docosanoid
