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Dysplasia

Index Dysplasia

Dysplasia (from Ancient Greek δυσ- dys-, "bad" or "difficult" and πλάσις plasis, "formation") is a term used in pathology to refer to an abnormality of development or an epithelial anomaly of growth and differentiation (epithelial dysplasia). [1]

32 relations: American Gastroenterological Association, Ancient Greek, Anisocytosis, Barrett's esophagus, Basement membrane, Biopsy, Blood, Bone marrow, Cancer, Carcinoma in situ, Cellular differentiation, Cervical intraepithelial neoplasia, Choosing Wisely, Colorectal cancer, Dysplasia, Ectoderm, Epithelial dysplasia, Epithelium, Fibrous dysplasia of bone, Hip dysplasia, List of biological development disorders, Metanephric dysplastic hematoma of the sacral region, Metaplasia, Metastasis, Multicystic dysplastic kidney, Myelodysplastic syndrome, Neoplasm, Pap test, Pathology, Poikilocytosis, Vaginal intraepithelial neoplasia, Vulvar intraepithelial neoplasia.

American Gastroenterological Association

The American Gastroenterological Association (AGA) is a medical association of gastroenterologists.

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Ancient Greek

The Ancient Greek language includes the forms of Greek used in ancient Greece and the ancient world from around the 9th century BC to the 6th century AD.

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Anisocytosis

Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size.

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Barrett's esophagus

Barrett's esophagus refers to an (abnormal) change in the cells of the lower portion of the esophagus. It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells (which are usually found lower in the gastrointestinal tract). The medical significance of Barrett's esophagus is its strong association (0.1 per 1 cm Prague C>M> total segment length per patient-year) with esophageal adenocarcinoma, a very often deadly cancer, because of which it is considered to be a premalignant condition. The main cause of Barrett's esophagus is thought to be an adaptation to chronic acid exposure from reflux esophagitis The incidence of esophageal adenocarcinoma has increased substantially in the Western world in recent years. The condition is found in 5–15% of patients who seek medical care for heartburn (gastroesophageal reflux disease), although a large subgroup of patients with Barrett's esophagus do not have symptoms. Diagnosis requires endoscopy (more specifically, esophagogastroduodenoscopy, a procedure in which a fibreoptic cable is inserted through the mouth to examine the esophagus, stomach, and duodenum) and biopsy. The cells of Barrett's esophagus, after biopsy, are classified into four general categories: nondysplastic, low-grade dysplasia, high-grade dysplasia, and frank carcinoma. High-grade dysplasia and early stages of adenocarcinoma can be treated by endoscopic resection and new endoscopic therapies such as radiofrequency ablation, whereas advanced stages (submucosal) are generally advised to undergo surgical treatment. Nondysplastic and low-grade patients are generally advised to undergo annual observation with endoscopy, with radiofrequency ablation as a therapeutic option. In high-grade dysplasia, the risk of developing cancer might be at 10% per patient-year or greater. The condition is named after the Australian-born British thoracic surgeon Norman Barrett (1903–1979), who described it in 1950. Those with the eating disorder bulimia are more likely to develop Barrett’s esophagus because bulimia can cause severe acid reflux, and because purging also floods the esophagus with acid.

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Basement membrane

The basement membrane is a thin, fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying connective tissue in metazoans.

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Biopsy

A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease.

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Blood

Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

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Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Carcinoma in situ

Carcinoma in situ (CIS), also known as in situ neoplasm, is a group of abnormal cells.

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Cervical intraepithelial neoplasia

Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer.

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Choosing Wisely

Choosing Wisely is a United States-based health educational campaign, led by the American Board of Internal Medicine (ABIM).

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Colorectal cancer

Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).

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Dysplasia

Dysplasia (from Ancient Greek δυσ- dys-, "bad" or "difficult" and πλάσις plasis, "formation") is a term used in pathology to refer to an abnormality of development or an epithelial anomaly of growth and differentiation (epithelial dysplasia).

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Ectoderm

Ectoderm is one of the three primary germ layers in the very early embryo.

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Epithelial dysplasia

Epithelial dysplasia, a term becoming increasingly referred to as intraepithelial neoplasia, is the sum of various disturbances of epithelial proliferation and differentiation as seen microscopically.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Fibrous dysplasia of bone

Fibrous dysplasia is a disorder where normal bone and marrow is replaced with fibrous tissue, resulting in formation of bone that is weak and prone to expansion.

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Hip dysplasia

Hip dysplasia is an abnormality of the hip joint where the socket portion does not fully cover the ball portion, resulting in an increased risk for joint dislocation.

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List of biological development disorders

No description.

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Metanephric dysplastic hematoma of the sacral region

Metanephric dysplastic hematoma of the sacral region (MDHSR) has been described by Cozzutto and Lazzaroni-Fossati in 1980, by Posalaki et al.

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Metaplasia

Metaplasia ("change in form") is the reversible transformation of one differentiated cell type to another differentiated cell type.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Multicystic dysplastic kidney

Multicystic dysplastic kidney (MCDK) is a condition that results from the malformation of the kidney during fetal development.

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Myelodysplastic syndrome

Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Pap test

The Papanicolaou test (abbreviated as Pap test, also known as Pap smear, cervical smear, or smear test) is a method of cervical screening used to detect potentially pre-cancerous and cancerous processes in the cervix (opening of the uterus or womb).

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Pathology

Pathology (from the Ancient Greek roots of pathos (πάθος), meaning "experience" or "suffering" and -logia (-λογία), "study of") is a significant field in modern medical diagnosis and medical research, concerned mainly with the causal study of disease, whether caused by pathogens or non-infectious physiological disorder.

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Poikilocytosis

Poikilocytosis refers to the presence of poikilocytes in the blood.

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Vaginal intraepithelial neoplasia

Vaginal intraepithelial neoplasia (VAIN) is a condition that describes premalignant histological findings in the vagina characterized by dysplastic changes.

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Vulvar intraepithelial neoplasia

Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin that covers the vulva.

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Redirects here:

Abnormally-formed joints, Dyplasia, Dysplasia of vulva, Dysplastic, Dysplastic cells, Dysplastic change, Fibula aplasia, Hyperchromasia, Hyperchromatic, Hyperchromatism, Precancerous cells, Vaginal dysplasia, Vulvar dysplasia.

References

[1] https://en.wikipedia.org/wiki/Dysplasia

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