Table of Contents
74 relations: Acetyltransferase, Adenosine, Adenosine diphosphate, Adenosine triphosphate, Aryl hydrocarbon receptor, Asthma, Autoimmune disease, Autoimmune regulator, Autoimmunity, Cancer, CD4, CD8, Central tolerance, Chromosome, Cluster of differentiation, Coding region, Cytokine, Cytotoxic T-lymphocyte associated protein 4, Diabetes, DNA, Endocrine disease, Enteropathy, ENTPD1, Exon, Fork head domain, FOX proteins, Frameshift mutation, Gene, Graft-versus-host disease, Histology, IL-10 family, IL2RA, Immune dysregulation, Immune system, Immune tolerance, Immunity (medicine), Immunosuppression, Inflammatory bowel disease, Interleukin 10, Interleukin 2, Interleukin 35, Intron, IPEX syndrome, Kidney disease, Leukemia, Locus (genetics), Lupus, Lymph node, Lymphocyte, Master regulator gene, ... Expand index (24 more) »
- Forkhead transcription factors
Acetyltransferase
Acetyltransferase (or transacetylase) is a type of transferase enzyme that transfers an acetyl group, through a process called acetylation.
See FOXP3 and Acetyltransferase
Adenosine
Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives.
Adenosine diphosphate
Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells.
See FOXP3 and Adenosine diphosphate
Adenosine triphosphate
Adenosine triphosphate (ATP) is a nucleotide that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis.
See FOXP3 and Adenosine triphosphate
Aryl hydrocarbon receptor
The aryl hydrocarbon receptor (also known as AhR, AHR, ahr, ahR, AH receptor, or as the dioxin receptor) is a protein that in humans is encoded by the AHR gene.
See FOXP3 and Aryl hydrocarbon receptor
Asthma
Asthma is a long-term inflammatory disease of the airways of the lungs.
See FOXP3 and Asthma
Autoimmune disease
An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.
See FOXP3 and Autoimmune disease
Autoimmune regulator
The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene.
See FOXP3 and Autoimmune regulator
Autoimmunity
In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents.
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
See FOXP3 and Cancer
CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR).
See FOXP3 and CD4
CD8
CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR).
See FOXP3 and CD8
Central tolerance
In immunology, central tolerance (also known as negative selection) is the process of eliminating any developing T or B lymphocytes that are autoreactive, i.e. reactive to the body itself.
See FOXP3 and Central tolerance
Chromosome
A chromosome is a package of DNA with part or all of the genetic material of an organism.
Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
See FOXP3 and Cluster of differentiation
Coding region
The coding region of a gene, also known as the coding sequence (CDS), is the portion of a gene's DNA or RNA that codes for a protein.
Cytokine
Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling.
Cytotoxic T-lymphocyte associated protein 4
Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses.
See FOXP3 and Cytotoxic T-lymphocyte associated protein 4
Diabetes
Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels.
DNA
Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.
See FOXP3 and DNA
Endocrine disease
Endocrine diseases are disorders of the endocrine system.
See FOXP3 and Endocrine disease
Enteropathy
Enteropathy refers to any pathology of the intestine.
ENTPD1
Ectonucleoside triphosphate diphosphohydrolase-1 (gene: ENTPD1; protein: NTPDase1) also known as CD39 (Cluster of Differentiation 39), is a typical cell surface enzyme with a catalytic site on the extracellular face.
See FOXP3 and ENTPD1
Exon
An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
See FOXP3 and Exon
Fork head domain
The fork head domain is a type of protein domain that is often found in transcription factors and whose purpose is to bind DNA.
See FOXP3 and Fork head domain
FOX proteins
FOX (forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. FOXP3 and FOX proteins are Forkhead transcription factors.
Frameshift mutation
A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three.
See FOXP3 and Frameshift mutation
Gene
In biology, the word gene has two meanings.
See FOXP3 and Gene
Graft-versus-host disease
Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs.
See FOXP3 and Graft-versus-host disease
Histology
Histology, also known as microscopic anatomy or microanatomy, is the branch of biology that studies the microscopic anatomy of biological tissues.
IL-10 family
The IL-10 family is a family of interleukins.
IL2RA
The Interleukin-2 receptor alpha chain (also called TAC antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity Interleukin-2 receptor, consisting of alpha (IL2RA), beta (IL2RB) and the common gamma chain (IL2RG).
See FOXP3 and IL2RA
Immune dysregulation
Immune dysregulation is any proposed or confirmed breakdown or maladaptive change in molecular control of immune system processes.
See FOXP3 and Immune dysregulation
Immune system
The immune system is a network of biological systems that protects an organism from diseases.
Immune tolerance
Immune tolerance, also known as immunological tolerance or immunotolerance, refers to the immune system's state of unresponsiveness to substances or tissues that would otherwise trigger an immune response.
See FOXP3 and Immune tolerance
Immunity (medicine)
In biology, immunity is the state of being insusceptible or resistant to a noxious agent or process, especially a pathogen or infectious disease.
See FOXP3 and Immunity (medicine)
Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system.
See FOXP3 and Immunosuppression
Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types.
See FOXP3 and Inflammatory bowel disease
Interleukin 10
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.
Interleukin 2
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system.
Interleukin 35
Interleukin 35 (IL-35) is a recently discovered anti-inflammatory cytokine from the IL-12 family.
Intron
An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product.
See FOXP3 and Intron
IPEX syndrome
Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX syndrome) is a rare autoimmune disease.
Kidney disease
Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney.
Leukemia
Leukemia (also spelled leukaemia; pronounced) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells.
Locus (genetics)
In genetics, a locus (loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located.
See FOXP3 and Locus (genetics)
Lupus
Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
See FOXP3 and Lupus
Lymph node
A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system.
Lymphocyte
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates.
Master regulator gene
In genetics, a master regulator gene is a regulator gene at the top of a gene regulation hierarchy, particularly in regulatory pathways related to cell fate and differentiation.
See FOXP3 and Master regulator gene
Melanoma
Melanoma is the most dangerous type of skin cancer; it develops from the melanin-producing cells known as melanocytes.
Multiple sclerosis
Multiple sclerosis (MS) is an autoimmune disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
See FOXP3 and Multiple sclerosis
NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival.
See FOXP3 and NF-κB
NFATC1
Nuclear factor of activated T-cells, cytoplasmic 1 is a protein that in humans is encoded by the NFATC1 gene.
See FOXP3 and NFATC1
Pancreatic cancer
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.
See FOXP3 and Pancreatic cancer
Phenotype
In genetics, the phenotype is the set of observable characteristics or traits of an organism.
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
Regulation of gene expression
Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA).
See FOXP3 and Regulation of gene expression
Regulatory T cell
The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.
See FOXP3 and Regulatory T cell
Sex linkage
Sex linked describes the sex-specific reading patterns of inheritance and presentation when a gene mutation (allele) is present on a sex chromosome (allosome) rather than a non-sex chromosome (autosome).
STAT protein
Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects of cellular immunity, proliferation, apoptosis and differentiation.
Stomach cancer
Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach.
Suppressor-inducer T cell
Suppressor-inducer T cells are a specific subset of CD4+ T helper cells that "induce" CD8+ cytotoxic T cells to become "suppressor" cells.
See FOXP3 and Suppressor-inducer T cell
T cell
T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response.
See FOXP3 and T cell
T helper 17 cell
T helper 17 cells (Th17) are a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17).
See FOXP3 and T helper 17 cell
Thymocyte
A thymocyte is an immune cell present in the thymus, before it undergoes transformation into a T cell.
Thymus
The thymus (thymuses or thymi) is a specialized primary lymphoid organ of the immune system.
See FOXP3 and Thymus
Thyroiditis
Thyroiditis is the inflammation of the thyroid gland.
Transcription (biology)
Transcription is the process of copying a segment of DNA into RNA.
See FOXP3 and Transcription (biology)
Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
See FOXP3 and Transcription factor
Transforming growth factor beta
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins.
See FOXP3 and Transforming growth factor beta
Type 1 diabetes
Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system.
Winged-helix transcription factors
Consisting of about 110 amino acids, the domain in winged-helix transcription factors (see Regulation of gene expression) has four helices and a two-strand beta-sheet.
See FOXP3 and Winged-helix transcription factors
X chromosome
The X chromosome is one of the two sex chromosomes in many organisms, including mammals, and is found in both males and females. FOXP3 and x chromosome are genes on human chromosome X.
See also
Forkhead transcription factors
- FOX proteins
- FOXA1
- FOXA2
- FOXA3
- FOXC2
- FOXD3
- FOXD4
- FOXE1
- FOXE3
- FOXF1
- FOXF2
- FOXG1
- FOXH1
- FOXI1
- FOXI3
- FOXJ1
- FOXJ2
- FOXK1
- FOXK2
- FOXL2
- FOXM1
- FOXN1
- FOXN3
- FOXO3
- FOXO4
- FOXO6
- FOXP1
- FOXP2
- FOXP3
- FOXP4
- FOXQ1
- FOXS1
- Forkhead box C1
- Forkhead box b1
- Forkhead box d1
- Forkhead box protein O1
References
Also known as FOXP3 (gene).