GABAA receptor and Muscimol

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Difference between GABAA receptor and Muscimol

GABAA receptor vs. Muscimol

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel. Muscimol (also known as agarin or pantherine) is one of the principal psychoactive constituents of Amanita muscaria and related species of mushroom.

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Barbiturate

A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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Euphoria

Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.

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GABAA-rho receptor

The GABAA-rho receptor (previously known as the GABAC receptor) is a subclass of GABAA receptors composed entirely of rho (ρ) subunits.

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Gaboxadol

Gaboxadol, also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP), is a conformationally constrained derivative of the alkaloid muscimol that was first synthesized in 1977 by the Danish chemist Povl Krogsgaard-Larsen.

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Gamma-Aminobutyric acid

gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.

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Hallucinogen

A hallucinogen is a psychoactive agent which can cause hallucinations, perceptual anomalies, and other substantial subjective changes in thoughts, emotion, and consciousness.

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Hypnotic

Hypnotic (from Greek Hypnos, sleep) or soporific drugs, commonly known as sleeping pills, are a class of psychoactive drugs whose primary function is to induce sleep and to be used in the treatment of insomnia (sleeplessness), or surgical anesthesia.

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Inhibitory postsynaptic potential

An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

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Z-drug

Z-drugs are a group of nonbenzodiazepine drugs with effects similar to benzodiazepines, which are used in the treatment of trouble sleeping, and most of whose names start with the letter "Z".

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Zolpidem

Zolpidem, sold under the brand name Ambien, among others, is a sedative primarily used for the treatment of trouble sleeping.

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