Innate immune system and Pyroptosis

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Difference between Innate immune system and Pyroptosis

Innate immune system vs. Pyroptosis

The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms. Pyroptosis is a highly inflammatory form of programmed cell death that occurs most frequently upon infection with intracellular pathogens and is likely to form part of the antimicrobial response.

Adaptive immune system

The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

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Antimicrobial

An antimicrobial is an agent that kills microorganisms or stops their growth.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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NOD-like receptor

The nucleotide-binding oligomerization domain-like receptors, in short NOD-like receptors (NLRs), are intracellular sensors of PAMPs that enter the cell via phagocytosis or pores and DAMPs that are associated with cell stress.

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Pathogen-associated molecular pattern

Pathogen-associated molecular patterns, or PAMPs, are molecules associated with groups of pathogens, that are recognized by cells of the innate immune system.

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Pattern recognition receptor

Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system.

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Programmed cell death

Programmed cell death (or PCD) is the death of a cell in any form, mediated by an intracellular program.

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Salmonella

Salmonella is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae.

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Toll-like receptor

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system.

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Tumor necrosis factor superfamily

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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