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Nicotine

Index Nicotine

Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) and is widely used recreationally as a stimulant and anxiolytic. [1]

Table of Contents

  1. 336 relations: Absorption (pharmacology), Acetaldehyde, Acid, Adaptive immune system, Addiction, Adolf Pinner, Adrenaline, Adrenergic agonist, Adrenergic receptor, Affect (psychology), Agonist, Alcohol (drug), Alertness, Alkaloid, Alpha blocker, Alpha-3 beta-4 nicotinic receptor, Alzheimer's disease, Amé Pictet, Anabasine, Analeptic, Analgesic, Angiogenesis, Anhedonia, Animal studies, Anxiolytic, Application site reaction, Arachidonate 5-lipoxygenase, Attention deficit hyperactivity disorder, Base (chemistry), Beta blocker, Biological half-life, Birth weight, Blinded experiment, Blood, Blood plasma, Blood pressure, Blood sugar level, Blood–brain barrier, BMC Public Health, Bradycardia, Bradypnea, Brain, Breathing, Buccal administration, Caffeine, Calcium, Capsicum, Cardiac arrest, Central melanocortin system, Chemical formula, ... Expand index (286 more) »

  2. Alkaloids found in Erythroxylum coca
  3. Alkaloids found in Nicotiana
  4. Plant toxin insecticides
  5. Pregnane X receptor agonists
  6. Pyridine alkaloids
  7. Pyrrolidine alkaloids

Absorption (pharmacology)

Absorption is the journey of a drug travelling from the site of administration to the site of action.

See Nicotine and Absorption (pharmacology)

Acetaldehyde

Acetaldehyde (IUPAC systematic name ethanal) is an organic chemical compound with the formula CH3 CHO, sometimes abbreviated as MeCHO.

See Nicotine and Acetaldehyde

Acid

An acid is a molecule or ion capable of either donating a proton (i.e. hydrogen ion, H+), known as a Brønsted–Lowry acid, or forming a covalent bond with an electron pair, known as a Lewis acid.

See Nicotine and Acid

Adaptive immune system

The adaptive immune system, also known as the acquired immune system, or specific immune system is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

See Nicotine and Adaptive immune system

Addiction

Addiction is a neuropsychological disorder characterized by a persistent and intense urge to use a drug or engage in a behavior that produces natural reward, despite substantial harm and other negative consequences.

See Nicotine and Addiction

Adolf Pinner

Adolf Pinner (August 31, 1842 – May 21, 1909) was a German chemist.

See Nicotine and Adolf Pinner

Adrenaline

Adrenaline, also known as epinephrine, is a hormone and medication which is involved in regulating visceral functions (e.g., respiration).

See Nicotine and Adrenaline

Adrenergic agonist

An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors.

See Nicotine and Adrenergic agonist

Adrenergic receptor

The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example.

See Nicotine and Adrenergic receptor

Affect (psychology)

Affect, in psychology, is the underlying experience of feeling, emotion, attachment, or mood.

See Nicotine and Affect (psychology)

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

See Nicotine and Agonist

Alcohol (drug)

Alcohol, sometimes referred to by the chemical name ethanol, is one of the most widely used and abused psychoactive drugs in the world and falls under the depressant category. Nicotine and Alcohol (drug) are anxiolytics, Euphoriants, nicotinic agonists and Teratogens.

See Nicotine and Alcohol (drug)

Alertness

Alertness is a state of active attention characterized by high sensory awareness.

See Nicotine and Alertness

Alkaloid

Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom.

See Nicotine and Alkaloid

Alpha blocker

Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors).

See Nicotine and Alpha blocker

Alpha-3 beta-4 nicotinic receptor

The alpha-3 beta-4 nicotinic receptor, also known as the α3β4 receptor and the ganglion-type nicotinic receptor,Pharmacology, (Rang, Dale, Ritter & Moore,, 5th ed., Churchill Livingstone 2003) p. 138.

See Nicotine and Alpha-3 beta-4 nicotinic receptor

Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.

See Nicotine and Alzheimer's disease

Amé Pictet

Amé Pictet (July 12, 1857 – March 11, 1937) was a Swiss chemist.

See Nicotine and Amé Pictet

Anabasine

Anabasine is a pyridine and piperidine alkaloid found in the tree tobacco (Nicotiana glauca) plant, as well as in tree tobacco's close relative the common tobacco plant (Nicotiana tabacum). Nicotine and Anabasine are 3-Pyridyl compounds, alkaloids found in Nicotiana, nicotinic agonists, plant toxin insecticides and pyridine alkaloids.

See Nicotine and Anabasine

Analeptic

An analeptic, in medicine, is a central nervous system stimulant.

See Nicotine and Analeptic

Analgesic

An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.

See Nicotine and Analgesic

Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis.

See Nicotine and Angiogenesis

Anhedonia

Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure.

See Nicotine and Anhedonia

Animal studies

Animal studies is a recently recognised field in which animals are studied in a variety of cross-disciplinary ways.

See Nicotine and Animal studies

Anxiolytic

An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety. Nicotine and anxiolytic are anxiolytics.

See Nicotine and Anxiolytic

Application site reaction

Application site reactions are reactions to medical treatments which occur at the site of application.

See Nicotine and Application site reaction

Arachidonate 5-lipoxygenase

Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans is encoded by the ALOX5 gene.

See Nicotine and Arachidonate 5-lipoxygenase

Attention deficit hyperactivity disorder

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and otherwise age-inappropriate.

See Nicotine and Attention deficit hyperactivity disorder

Base (chemistry)

In chemistry, there are three definitions in common use of the word "base": Arrhenius bases, Brønsted bases, and Lewis bases.

See Nicotine and Base (chemistry)

Beta blocker

Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms (arrhythmia), and to protect the heart from a second heart attack after a first heart attack (secondary prevention).

See Nicotine and Beta blocker

Biological half-life

Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.

See Nicotine and Biological half-life

Birth weight

Birth weight is the body weight of a baby at their birth.

See Nicotine and Birth weight

Blinded experiment

In a blind or blinded experiment, information which may influence the participants of the experiment is withheld until after the experiment is complete.

See Nicotine and Blinded experiment

Blood

Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells.

See Nicotine and Blood

Blood plasma

Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension.

See Nicotine and Blood plasma

Blood pressure

Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels.

See Nicotine and Blood pressure

Blood sugar level

The blood sugar level, blood sugar concentration, blood glucose level, or glycemia is the measure of glucose concentrated in the blood.

See Nicotine and Blood sugar level

Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood.

See Nicotine and Blood–brain barrier

BMC Public Health

BMC Public Health is a peer-reviewed open-access scientific journal that covers epidemiology of disease and various aspects of public health.

See Nicotine and BMC Public Health

Bradycardia

Bradycardia, also called bradyarrhythmia, is a resting heart rate under 60 beats per minute (BPM).

See Nicotine and Bradycardia

Bradypnea

Bradypnea is abnormally slow breathing.

See Nicotine and Bradypnea

Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

See Nicotine and Brain

Breathing

Breathing (spiration or ventilation) is the rhythmical process of moving air into (inhalation) and out of (exhalation) the lungs to facilitate gas exchange with the internal environment, mostly to flush out carbon dioxide and bring in oxygen.

See Nicotine and Breathing

Buccal administration

Buccal administration is a topical route of administration by which drugs held or applied in the buccal area (in the cheek) diffuse through the oral mucosa (tissues which line the mouth) and enter directly into the bloodstream.

See Nicotine and Buccal administration

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class. Nicotine and Caffeine are plant toxin insecticides and stimulants.

See Nicotine and Caffeine

Calcium

Calcium is a chemical element; it has symbol Ca and atomic number 20.

See Nicotine and Calcium

Capsicum

Capsicum is a genus of flowering plants in the nightshade family Solanaceae, native to the Americas, cultivated worldwide for their edible fruit.

See Nicotine and Capsicum

Cardiac arrest

Cardiac arrest, also known as sudden cardiac arrest, is when the heart suddenly and unexpectedly stops beating.

See Nicotine and Cardiac arrest

Central melanocortin system

The central melanocortin system is defined anatomically as a collection of central nervous system circuits which include.

See Nicotine and Central melanocortin system

Chemical formula

A chemical formula is a way of presenting information about the chemical proportions of atoms that constitute a particular chemical compound or molecule, using chemical element symbols, numbers, and sometimes also other symbols, such as parentheses, dashes, brackets, commas and plus (+) and minus (−) signs.

See Nicotine and Chemical formula

Chewing tobacco

Chewing tobacco is a type of smokeless tobacco product that is placed between the cheek and lower gum to draw out its flavor.

See Nicotine and Chewing tobacco

Chirality

Chirality is a property of asymmetry important in several branches of science.

See Nicotine and Chirality

Chirality (chemistry)

In chemistry, a molecule or ion is called chiral if it cannot be superposed on its mirror image by any combination of rotations, translations, and some conformational changes.

See Nicotine and Chirality (chemistry)

CHRNA10

Neuronal acetylcholine receptor subunit alpha-10, also known as nAChRα10 and cholinergic receptor nicotinic alpha 10, is a protein that in humans is encoded by the CHRNA10 gene.

See Nicotine and CHRNA10

CHRNA9

Neuronal acetylcholine receptor subunit alpha-9, also known as nAChRα9, is a protein that in humans is encoded by the CHRNA9 gene.

See Nicotine and CHRNA9

Chromaffin cell

Chromaffin cells, also called pheochromocytes (or phaeochromocytes), are neuroendocrine cells found mostly in the medulla of the adrenal glands in mammals.

See Nicotine and Chromaffin cell

Chromosome abnormality

A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder is a missing, extra, or irregular portion of chromosomal DNA.

See Nicotine and Chromosome abnormality

Cigar

A cigar is a tobacco product made to be smoked.

See Nicotine and Cigar

Cigarette

A cigarette is a narrow cylinder containing a combustible material, typically tobacco, that is rolled into thin paper for smoking.

See Nicotine and Cigarette

Circulatory system

The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate.

See Nicotine and Circulatory system

Cochrane (organisation)

Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers.

See Nicotine and Cochrane (organisation)

Coma

A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions.

See Nicotine and Coma

Comet assay

The single cell gel electrophoresis assay (SCGE, also known as comet assay) is an uncomplicated and sensitive technique for the detection of DNA damage at the level of the individual eukaryotic cell.

See Nicotine and Comet assay

Confusion

In medicine, confusion is the quality or state of being bewildered or unclear.

See Nicotine and Confusion

Consolidated Appropriations Act, 2022

Consolidated Appropriations Act, 2022 is a $1.5 trillion omnibus spending bill passed by the 117th United States Congress on March 14, 2022 and signed into law by President Joe Biden the following day.

See Nicotine and Consolidated Appropriations Act, 2022

Contraindication

In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient.

See Nicotine and Contraindication

Cotinine

Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, typically used as a biomarker for exposure to tobacco smoke. Nicotine and Cotinine are 3-Pyridyl compounds, alkaloids found in Nicotiana, nicotinic agonists and pyridine alkaloids.

See Nicotine and Cotinine

CYP2A6

Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.

See Nicotine and CYP2A6

CYP2B6

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene.

See Nicotine and CYP2B6

Cytochrome P450

Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.

See Nicotine and Cytochrome P450

D1-like receptor

The D1-like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine.

See Nicotine and D1-like receptor

Dalton (unit)

The dalton or unified atomic mass unit (symbols: Da or u) is a non-SI unit of mass defined as of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest.

See Nicotine and Dalton (unit)

DC Comics

DC Comics, Inc. (doing business as DC) is an American comic book publisher and the flagship unit of DC Entertainment, a subsidiary of Warner Bros. Discovery.

See Nicotine and DC Comics

Deamination

Deamination is the removal of an amino group from a molecule.

See Nicotine and Deamination

Decarboxylation

Decarboxylation is a chemical reaction that removes a carboxyl group and releases carbon dioxide (CO2).

See Nicotine and Decarboxylation

Dementia

Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform everyday activities.

See Nicotine and Dementia

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Nicotine and Depression (mood)

Development of the nervous system

The development of the nervous system, or neural development (neurodevelopment), refers to the processes that generate, shape, and reshape the nervous system of animals, from the earliest stages of embryonic development to adulthood.

See Nicotine and Development of the nervous system

Dextropropoxyphene

Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company.

See Nicotine and Dextropropoxyphene

DNA damage (naturally occurring)

DNA damage is an alteration in the chemical structure of DNA, such as a break in a strand of DNA, a nucleobase missing from the backbone of DNA, or a chemically changed base such as 8-OHdG.

See Nicotine and DNA damage (naturally occurring)

Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells.

See Nicotine and Dopamine

Dosage form

Dosage forms (also called unit doses) are pharmaceutical drug products in the form in which they are marketed for use, with a specific mixture of active ingredients and inactive components (excipients), in a particular configuration (such as a capsule shell, for example), and apportioned into a particular dose.

See Nicotine and Dosage form

Dose (biochemistry)

A dose is a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit.

See Nicotine and Dose (biochemistry)

Dose–response relationship

The dose–response relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or doses) to a stimulus or stressor (usually a chemical) after a certain exposure time.

See Nicotine and Dose–response relationship

Drug metabolism

Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.

See Nicotine and Drug metabolism

Drug withdrawal

Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome, is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs.

See Nicotine and Drug withdrawal

Duboisia hopwoodii

Duboisia hopwoodii is a shrub native to the arid interior region of Australia.

See Nicotine and Duboisia hopwoodii

Eggplant

Eggplant (US, CA, AU, NZ, PH), aubergine (UK, IE), brinjal (IN, SG, MY, ZA), or baigan (IN, GY) is a plant species in the nightshade family Solanaceae.

See Nicotine and Eggplant

Electronic cigarette

An electronic cigarette (e-cigarette) or vape is a device that simulates tobacco smoking.

See Nicotine and Electronic cigarette

Empirical formula

In chemistry, the empirical formula of a chemical compound is the simplest whole number ratio of atoms present in a compound.

See Nicotine and Empirical formula

Enantiomer

In chemistry, an enantiomer (/ɪˈnænti.əmər, ɛ-, -oʊ-/ ''ih-NAN-tee-ə-mər''; from Ancient Greek ἐναντίος (enantíos) 'opposite', and μέρος (méros) 'part') – also called optical isomer, antipode, or optical antipode – is one of two stereoisomers that are nonsuperposable onto their own mirror image.

See Nicotine and Enantiomer

Energy expenditure

Energy expenditure, often estimated as the total daily energy expenditure (TDEE), is the amount of energy burned by the human body.

See Nicotine and Energy expenditure

Epidermal growth factor

Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR.

See Nicotine and Epidermal growth factor

Epithelial–mesenchymal transition

The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell–cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types.

See Nicotine and Epithelial–mesenchymal transition

Erythema

Erythema is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.

See Nicotine and Erythema

Euphoria

Euphoria is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. Nicotine and Euphoria are Euphoriants.

See Nicotine and Euphoria

Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

See Nicotine and Europe

Excretion

Excretion is elimination of metabolic waste, which is an essential process in all organisms.

See Nicotine and Excretion

Exocytosis

Exocytosis is a form of active transport and bulk transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell (exo- + cytosis).

See Nicotine and Exocytosis

Flash point

The flash point of a material is the "lowest liquid temperature at which, under certain standardized conditions, a liquid gives off vapours in a quantity such as to be capable of forming an ignitable vapour/air mixture".

See Nicotine and Flash point

Flatulence

Flatulence is the expulsion of gas from the intestines via the anus, commonly referred to as farting.

See Nicotine and Flatulence

Flavin-containing monooxygenase 3

Flavin-containing monooxygenase 3 (FMO3), also known as dimethylaniline monooxygenase 3 and trimethylamine monooxygenase, is a flavoprotein enzyme that in humans is encoded by the FMO3 gene.

See Nicotine and Flavin-containing monooxygenase 3

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Nicotine and Food and Drug Administration

FOSB

Protein fosB, also known as FosB and G0/G1 switch regulatory protein 3 (G0S3), is a protein that in humans is encoded by the FBJ murine osteosarcoma viral oncogene homolog B (FOSB) gene.

See Nicotine and FOSB

FOSL1

Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene.

See Nicotine and FOSL1

FOSL2

Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.

See Nicotine and FOSL2

France

France, officially the French Republic, is a country located primarily in Western Europe.

See Nicotine and France

Free base

Free base (freebase, free-base) is a descriptor for the neutral form of an amine commonly used in reference to illicit drugs.

See Nicotine and Free base

Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype.

See Nicotine and Gene expression

Genotoxicity

Genotoxicity is the property of chemical agents that damage the genetic information within a cell causing mutations, which may lead to cancer.

See Nicotine and Genotoxicity

Germany

Germany, officially the Federal Republic of Germany (FRG), is a country in Central Europe.

See Nicotine and Germany

Ghrelin

Ghrelin (or lenomorelin, INN) is a hormone primarily produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach, and is often called a "hunger hormone" because it increases the drive to eat.

See Nicotine and Ghrelin

Glucuronidation

Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.

See Nicotine and Glucuronidation

Glyceraldehyde 3-phosphate

Glyceraldehyde 3-phosphate, also known as triose phosphate or 3-phosphoglyceraldehyde and abbreviated as G3P, GA3P, GADP, GAP, TP, GALP or PGAL, is a metabolite that occurs as an intermediate in several central pathways of all organisms.

See Nicotine and Glyceraldehyde 3-phosphate

Green Tobacco Sickness

Green Tobacco Sickness (GTS) is a type of nicotine poisoning caused by the transdermal absorption of nicotine from the surface of tobacco plants.

See Nicotine and Green Tobacco Sickness

Growth factor

A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation.

See Nicotine and Growth factor

Harm reduction

Harm reduction, or harm minimization, refers to a range of intentional practices and public health policies designed to lessen the negative social and/or physical consequences associated with various human behaviors, both legal and illegal.

See Nicotine and Harm reduction

Hazardous Substances Data Bank

The Hazardous Substances Data Bank (HSDB) was a toxicology database on the U.S. National Library of Medicine's (NLM) Toxicology Data Network (TOXNET).

See Nicotine and Hazardous Substances Data Bank

Heart rate

Heart rate is the frequency of the heartbeat measured by the number of contractions of the heart per minute (beats per minute, or bpm).

See Nicotine and Heart rate

Histone deacetylase

Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.

See Nicotine and Histone deacetylase

Hormone

A hormone (from the Greek participle ὁρμῶν, "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior.

See Nicotine and Hormone

Human brain

The brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system.

See Nicotine and Human brain

Hygroscopy

Hygroscopy is the phenomenon of attracting and holding water molecules via either absorption or adsorption from the surrounding environment, which is usually at normal or room temperature.

See Nicotine and Hygroscopy

Hypersalivation

Hypersalivation or hypersialosis is the excessive production of saliva.

See Nicotine and Hypersalivation

Hypersensitivity

Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen.

See Nicotine and Hypersensitivity

Hypertension

Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

See Nicotine and Hypertension

Hypotension

Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure.

See Nicotine and Hypotension

Imidacloprid

Imidacloprid is a systemic insecticide belonging to a class of chemicals called the neonicotinoids which act on the central nervous system of insects.

See Nicotine and Imidacloprid

Immediately dangerous to life or health

The term immediately dangerous to life or health (IDLH) is defined by the US National Institute for Occupational Safety and Health (NIOSH) as exposure to airborne contaminants that is "likely to cause death or immediate or delayed permanent adverse health effects or prevent escape from such an environment." Examples include smoke or other poisonous gases at sufficiently high concentrations.

See Nicotine and Immediately dangerous to life or health

Immune system

The immune system is a network of biological systems that protects an organism from diseases.

See Nicotine and Immune system

In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

See Nicotine and In vivo

Indigestion

Indigestion, also known as dyspepsia or upset stomach, is a condition of impaired digestion.

See Nicotine and Indigestion

Infertility

Infertility is the inability of an animal or plant to reproduce by natural means.

See Nicotine and Infertility

Inhalation

Inhalation (or inspiration) happens when air or other gases enter the lungs.

See Nicotine and Inhalation

Insecticide

Insecticides are pesticides used to kill insects.

See Nicotine and Insecticide

Insomnia

Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.

See Nicotine and Insomnia

Insufflation (medicine)

Insufflation (lit) is the act of blowing something (such as a gas, powder, or vapor) into a body cavity.

See Nicotine and Insufflation (medicine)

International Agency for Research on Cancer

The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.

See Nicotine and International Agency for Research on Cancer

Ischemia

Ischemia or ischaemia is a restriction in blood supply to any tissue, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

See Nicotine and Ischemia

Isomer

In chemistry, isomers are molecules or polyatomic ions with identical molecular formula – that is, the same number of atoms of each element – but distinct arrangements of atoms in space.

See Nicotine and Isomer

Itch

An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch.

See Nicotine and Itch

Jasmonate

Jasmonate (JA) and its derivatives are lipid-based plant hormones that regulate a wide range of processes in plants, ranging from growth and photosynthesis to reproductive development.

See Nicotine and Jasmonate

Jean Nicot

Jean Nicot de Villemain (1530 – 4 May 1604) was a French diplomat and scholar.

See Nicotine and Jean Nicot

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Nicotine and Kidney

Kilogram

The kilogram (also kilogramme) is the base unit of mass in the International System of Units (SI), having the unit symbol kg.

See Nicotine and Kilogram

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Nicotine and Ligand (biochemistry)

List of common misconceptions

Each entry on this list of common misconceptions is worded as a correction; the misconceptions themselves are implied rather than stated.

See Nicotine and List of common misconceptions

List of tobacco products

Tobacco is the agricultural product of the leaves of plants in the genus Nicotiana, commonly termed tobacco plants.

See Nicotine and List of tobacco products

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Nicotine and Liver

Louis Melsens

Louis Henri Frédéric Melsens (11 July 1814 in Leuven – 20 April 1886 in Brussels) was a Belgian physicist and chemist.

See Nicotine and Louis Melsens

Lymphocyte

A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates.

See Nicotine and Lymphocyte

Major depressive disorder

Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities.

See Nicotine and Major depressive disorder

Mammal

A mammal is a vertebrate animal of the class Mammalia.

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Manduca sexta

Manduca sexta is a moth of the family Sphingidae present through much of the Americas.

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McMaster University

McMaster University (McMaster or Mac) is a public research university in Hamilton, Ontario, Canada.

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Median lethal dose

In toxicology, the median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance.

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Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Medium spiny neuron

Medium spiny neurons (MSNs), also known as spiny projection neurons (SPNs), are a special type of inhibitory GABAergic neuron representing approximately 90% of neurons within the human striatum, a basal ganglia structure.

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Menthol

Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints.

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Menthol cigarette

A menthol cigarette is a cigarette infused with the compound menthol which imparts a “minty” flavor to the smoke.

See Nicotine and Menthol cigarette

Mesolimbic pathway

The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

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Metered-dose inhaler

A metered-dose inhaler (MDI) is a device that delivers a specific amount of medication to the lungs in the form of a short burst of aerosolized medicine that is usually self-administered by the patient via inhalation.

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Methylamine

Methylamine is an organic compound with a formula of.

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Methylation

Methylation, in the chemical sciences, is the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

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Microgram

In the metric system, a microgram or microgramme is a unit of mass equal to one millionth of a gram.

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Micronucleus test

A micronucleus test is a test used in toxicological screening for potential genotoxic compounds.

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Miscarriage

Miscarriage, also known in medical terms as a spontaneous abortion, is the death and expulsion of an embryo or fetus before it can survive independently.

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Miscibility

Miscibility is the property of two substances to mix in all proportions (that is, to fully dissolve in each other at any concentration), forming a homogeneous mixture (a solution).

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Mitogen

A mitogen is a small bioactive protein or peptide that induces a cell to begin cell division, or enhances the rate of division (mitosis).

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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

See Nicotine and Monoamine oxidase inhibitor

Mouth ulcer

A mouth ulcer (aphtha) is an ulcer that occurs on the mucous membrane of the oral cavity.

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Myalgia

Myalgia or muscle pain is a painful sensation evolving from muscle tissue.

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Myocardial infarction

A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle.

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Myosmine

Myosmine is an alkaloid found in tobacco and other plants. Nicotine and Myosmine are 3-Pyridyl compounds, alkaloids found in Nicotiana, nicotinic agonists and pyridine alkaloids.

See Nicotine and Myosmine

N-Nitrosonornicotine

N-Nitrosonornicotine (NNN) is a tobacco-specific nitrosamine produced during the curing and processing of tobacco. Nicotine and n-Nitrosonornicotine are 3-Pyridyl compounds.

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Nasal administration

Nasal administration, popularly known as snorting, is a route of administration in which drugs are insufflated through the nose.

See Nicotine and Nasal administration

National Academies of Sciences, Engineering, and Medicine

The National Academies of Sciences, Engineering, and Medicine (NASEM), also known as the National Academies, is a congressionally chartered organization that serves as the collective scientific national academy of the United States.

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National Institute for Occupational Safety and Health

The National Institute for Occupational Safety and Health (NIOSH) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness.

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Natural product

A natural product is a natural compound or substance produced by a living organism—that is, found in nature.

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Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

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Neonicotinoid

Neonicotinoids (sometimes shortened to neonics) are a class of neuro-active insecticides chemically similar to nicotine, developed by scientists at Shell and Bayer in the 1980s.

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Neovascularization

Neovascularization is the natural formation of new blood vessels (neo- + vascular + -ization), usually in the form of functional microvascular networks, capable of perfusion by red blood cells, that form to serve as collateral circulation in response to local poor perfusion or ischemia.

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Neuronal acetylcholine receptor subunit alpha-5

The neuronal acetylcholine receptor subunit alpha-5, or alpha-5 nicotinic acetylcholine receptor (α5 nAChR) also known as the α5 receptor is a type of ligand gated neuronal type subunit of the nicotinic acetylcholine receptor involved in pain regulation encoded in the human by the CHRNA5 gene.

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Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away.

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Neurotransmitter

A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse.

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Niacin

Niacin, also known as nicotinic acid, is an organic compound and a vitamer ofvitamin B3, an essential human nutrient. Nicotine and Niacin are 3-Pyridyl compounds.

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Nick O'Teen

Nick O'Teen is a fictional supervillain from British anti-smoking public service announcements in the 1980s, created by Saatchi & Saatchi and the Health Education Council of London in collaboration with DC Comics.

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Nicotiana

Nicotiana is a genus of herbaceous plants and shrubs in the family Solanaceae, that is indigenous to the Americas, Australia, Southwestern Africa and the South Pacific.

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Nicotiana rustica

Nicotiana rustica, commonly known as Aztec tobacco or strong tobacco, is a rainforest plant in the family Solanaceae native to South America. Nicotine and Nicotiana rustica are plant toxin insecticides.

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Nicotiana tabacum

Nicotiana tabacum, or cultivated tobacco, is an annually grown herbaceous plant of the genus Nicotiana.

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Nicotinamidase

In enzymology, a nicotinamidase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are nicotinamide and H2O, whereas its two products are nicotinate and NH3.

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Nicotinamide

Niacinamide or nicotinamide is a form of vitamin B3 found in food and used as a dietary supplement and medication.

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Nicotine dependence

Nicotine dependence is a state of dependence upon nicotine. Nicotine and nicotine dependence are smoking.

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Nicotine gum

Nicotine gum is a chewing gum containing the active ingredient nicotine polacrilex.

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Nicotine lozenge

A nicotine lozenge is a modified-release dosage tablet (usually flavored) that contains a dose of nicotine polacrilex, which dissolves slowly in the mouth to release nicotine over the course of 20 to 30 minutes.

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Nicotine marketing

Nicotine marketing is the marketing of nicotine-containing products or use.

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Nicotine nasal spray

A nicotine nasal spray is a nasal spray that contains a small dose of nicotine, which enters the blood by being absorbed through the lining of the nose. Nicotine and nicotine nasal spray are smoking and stimulants.

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Nicotine patch

A nicotine patch is a transdermal patch that releases nicotine into the body through the skin.

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Nicotine poisoning

Nicotine poisoning describes the symptoms of the toxic effects of nicotine following ingestion, inhalation, or skin contact.

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Nicotine replacement therapy

Nicotine replacement therapy (NRT) is a medically approved way to treat people with tobacco use disorder by taking nicotine through means other than tobacco. Nicotine and nicotine replacement therapy are drugs developed by GSK plc.

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Nicotine salt

Nicotine salts are salts formed from nicotine and an acid. Nicotine and nicotine salt are stimulants.

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Nicotini

A nicotini is any alcoholic drink which includes nicotine as an ingredient.

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Nicotinic acetylcholine receptor

Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine.

See Nicotine and Nicotinic acetylcholine receptor

Nitrosation

Nitrosation is a process of converting organic compounds into nitroso derivatives, i.e., compounds containing the R-NO functionality.

See Nicotine and Nitrosation

Nootropic

Nootropics (or; but not or, which are common mispronunciations), colloquially brain supplements, smart drugs and cognitive enhancers, are natural, semisynthetic or synthetic compounds which purportedly improve cognitive functions, such as executive functions, attention or memory.

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Nucleotide base

Nucleotide bases (also nucleobases, nitrogenous bases) are nitrogen-containing biological compounds that form nucleosides, which, in turn, are components of nucleotides, with all of these monomers constituting the basic building blocks of nucleic acids.

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Nucleus accumbens

The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the nucleus accumbens septi, Latin for 'nucleus adjacent to the septum') is a region in the basal forebrain rostral to the preoptic area of the hypothalamus.

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Obesity

Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it can potentially have negative effects on health.

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Occupational Safety and Health Administration

The Occupational Safety and Health Administration (OSHA) is a regulatory agency of the United States Department of Labor that originally had federal visitorial powers to inspect and examine workplaces.

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Optical rotation

Optical rotation, also known as polarization rotation or circular birefringence, is the rotation of the orientation of the plane of polarization about the optical axis of linearly polarized light as it travels through certain materials.

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Oral administration

| name.

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Oral mucosa

The oral mucosa is the mucous membrane lining the inside of the mouth.

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Ornithine

Ornithine is a non-proteinogenic α-amino acid that plays a role in the urea cycle.

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Ornithine decarboxylase

The enzyme ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine (a product of the urea cycle) to form putrescine.

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Outcrossing

Out-crossing or out-breeding is the technique of crossing between different breeds.

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Over-the-counter drug

Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.

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Pallor

Pallor is a pale color of the skin that can be caused by illness, emotional shock or stress, stimulant use, or anemia, and is the result of a reduced amount of oxyhaemoglobin and may also be visible as pallor of the conjunctivae of the eyes on physical examination.

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Palpitations

Palpitations are perceived abnormalities of the heartbeat characterized by awareness of cardiac muscle contractions in the chest, which is further characterized by the hard, fast and/or irregular beatings of the heart.

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Paracetamol

Paracetamol (acetaminophen) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain.

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Paradoxical reaction

A paradoxical reaction (or paradoxical effect) is an effect of a chemical substance, such as a medical drug, that is opposite to what would usually be expected.

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Paresthesia

Paresthesia is an abnormal sensation of the skin (tingling, pricking, chilling, burning, numbness) with no apparent physical cause.

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Paris

Paris is the capital and largest city of France.

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Parkinson's disease

Parkinson's disease (PD), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body.

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Parotid gland

The parotid gland is a major salivary gland in many animals.

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Parts-per notation

In science and engineering, the parts-per notation is a set of pseudo-units to describe small values of miscellaneous dimensionless quantities, e.g. mole fraction or mass fraction.

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Passive smoking

Passive smoking is the inhalation of tobacco smoke, called passive smoke, secondhand smoke (SHS) or environmental tobacco smoke (ETS), by individuals other than the active smoker. Nicotine and passive smoking are smoking.

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Paul Nesbitt

Paul Nesbitt (April 3, 1872July 22, 1950) was an American politician, who served as Speaker of the Oklahoma House of Representatives.

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Pentazocine

Pentazocine, sold under the brand name Talwin among others, is a painkiller used to treat moderate to severe pain.

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Performance-enhancing substance

Performance-enhancing substances, also known as performance-enhancing drugs (PEDs), are substances that are used to improve any form of activity performance in humans.

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Permissible exposure limit

The permissible exposure limit (PEL or OSHA PEL) is a legal limit in the United States for exposure of an employee to a chemical substance or physical agent such as high level noise.

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PH

In chemistry, pH, also referred to as acidity or basicity, historically denotes "potential of hydrogen" (or "power of hydrogen").

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Pharmacodynamics

Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration.

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Pharmacology & Therapeutics

Pharmacology & Therapeutics is a medical review journal published by Elsevier.

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Pharmacotherapy

Pharmacotherapy, also known as pharmacological therapy or drug therapy, is defined as medical treatment that utilizes one or more pharmaceutical drugs to improve ongoing symptoms (symptomatic relief), treat the underlying condition, or act as a prevention for other diseases (prophylaxis).

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Phosphorylation

In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion.

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Photoactivatable probes

Photoactivatable probes, or caged probes, are cellular players (proteins, nucleic acids, small molecules) that can be triggered by a flash of light.

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Physical dependence

Physical dependence is a physical condition caused by chronic use of a tolerance-forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.

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Pipe smoking

Pipe smoking is the practice of tasting (or, less commonly, inhaling) the smoke produced by burning a substance, most commonly tobacco or cannabis, in a pipe. Nicotine and pipe smoking are smoking.

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Placebo

A placebo is a substance or treatment which is designed to have no therapeutic value.

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Placenta

The placenta (placentas or placentae) is a temporary embryonic and later fetal organ that begins developing from the blastocyst shortly after implantation.

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Plant defense against herbivory

Plant defense against herbivory or host-plant resistance (HPR) is a range of adaptations evolved by plants which improve their survival and reproduction by reducing the impact of herbivores.

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Portugal

Portugal, officially the Portuguese Republic, is a country located on the Iberian Peninsula in Southwestern Europe, whose territory also includes the Macaronesian archipelagos of the Azores and Madeira.

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Potato

The potato is a starchy root vegetable native to the Americas that is consumed as a staple food in many parts of the world.

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Prescription drug

A prescription drug (also prescription medication, prescription medicine or prescription-only medication) is a pharmaceutical drug that is permitted to be dispensed only to those with a medical prescription.

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Programmed cell death

Programmed cell death (PCD; sometimes referred to as cellular suicide) is the death of a cell as a result of events inside of a cell, such as apoptosis or autophagy.

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Proopiomelanocortin

Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues.

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Protein c-Fos

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.

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Protein isoform

A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

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Psychological dependence

Psychological dependence is a cognitive disorder that involves emotional–motivational withdrawal symptoms – such as anxiety or anhedonia – upon cessation of prolonged drug abuse or certain repetitive behaviors.

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Psychopharmacology

Psychopharmacology (from Greek label; label; and label) is the scientific study of the effects drugs have on mood, sensation, thinking, behavior, judgment and evaluation, and memory.

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PubChem

PubChem is a database of chemical molecules and their activities against biological assays.

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Public service announcement

A public service announcement (PSA) is a message in the public interest disseminated by the media without charge to raise public awareness and change behavior.

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Putrescine

Putrescine is an organic compound with the formula (CH2)4(NH2)2.

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Putrescine N-methyltransferase

In enzymology, a putrescine N-methyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl methionine and putrescine, whereas its two products are S-adenosylhomocysteine and N-methylputrescine.

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Pyridine

Pyridine is a basic heterocyclic organic compound with the chemical formula.

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Pyrrole

Pyrrole is a heterocyclic, aromatic, organic compound, a five-membered ring with the formula.

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Pyrrolidine

Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH2)4NH.

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Quinolinic acid

Quinolinic acid (abbreviated QUIN or QA), also known as pyridine-2,3-dicarboxylic acid, is a dicarboxylic acid with a pyridine backbone.

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Racemic mixture

In chemistry, a racemic mixture or racemate is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt.

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Rapid eye movement sleep

Rapid eye movement sleep (REM sleep or REMS) is a unique phase of sleep in mammals (including humans) and birds, characterized by random rapid movement of the eyes, accompanied by low muscle tone throughout the body, and the propensity of the sleeper to dream vividly.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Nicotine and Receptor antagonist

A recommended exposure limit (REL) is an occupational exposure limit that has been recommended by the United States National Institute for Occupational Safety and Health.

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Recreational drug use

Recreational drug use is the use of one or more psychoactive drugs to induce an altered state of consciousness, either for pleasure or for some other casual purpose or pastime.

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Respiratory failure

Respiratory failure results from inadequate gas exchange by the respiratory system, meaning that the arterial oxygen, carbon dioxide, or both cannot be kept at normal levels.

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Rhinitis

Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose.

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Richard Wolffenstein (chemist)

Richard Wolffenstein (21 August 1864 – 5 June 1926) was a German chemist.

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Route of administration

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body.

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Saliva

Saliva (commonly referred to as spit or drool) is an extracellular fluid produced and secreted by salivary glands in the mouth.

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Salt (chemistry)

In chemistry, a salt or ionic compound is a chemical compound consisting of an assembly of positively charged ions (cations) and negatively charged ions (anions), which results in a compound with no net electric charge (electrically neutral).

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Sarcoma

A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin.

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Secondary metabolite

Secondary metabolites, also called specialised metabolites, toxins, secondary products, or natural products, are organic compounds produced by any lifeform, e.g. bacteria, fungi, animals, or plants, which are not directly involved in the normal growth, development, or reproduction of the organism.

See Nicotine and Secondary metabolite

Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

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Seizure

A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

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Shortness of breath

Shortness of breath (SOB), known as dyspnea (in AmE) or dyspnoea (in BrE), is an uncomfortable feeling of not being able to breathe well enough.

See Nicotine and Shortness of breath

Sigmatropic reaction

A sigmatropic reaction in organic chemistry is a pericyclic reaction wherein the net result is one σ-bond is changed to another σ-bond in an uncatalyzed intramolecular reaction.

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Signs and symptoms

Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition.

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Skeletal muscle

Skeletal muscle (commonly referred to as muscle) is one of the three types of vertebrate muscle tissue, the other being cardiac muscle and smooth muscle.

See Nicotine and Skeletal muscle

Sleep onset latency

In sleep science, sleep onset latency (SOL) is the length of time that it takes to accomplish the transition from full wakefulness to sleep, normally to the lightest of the non-REM sleep stages.

See Nicotine and Sleep onset latency

Slow-wave sleep

Slow-wave sleep (SWS), often referred to as deep sleep, is the third stage of non-rapid eye movement sleep (NREM), where electroencephalography activity is characterised by slow delta waves.

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Smoking

Smoking is a practice in which a substance is combusted and the resulting smoke is typically inhaled to be tasted and absorbed into the bloodstream of a person.

See Nicotine and Smoking

Smoking cessation

Smoking cessation, usually called quitting smoking or stopping smoking, is the process of discontinuing tobacco smoking. Nicotine and smoking cessation are smoking.

See Nicotine and Smoking cessation

Snuff (tobacco)

Snuff is a type of smokeless tobacco product made from finely ground or pulverized tobacco leaves. Nicotine and Snuff (tobacco) are smoking.

See Nicotine and Snuff (tobacco)

Snus

Snus is a tobacco product (in Scandinavia) and non-tobacco nicotine product (outside of Scandinavia; often marketed as nicotine pouches) consumed by placing a pouch of powdered tobacco leaves or powdered non-tobacco plant fibers under your lip for nicotine to be absorbed through the oral mucosa.

See Nicotine and Snus

Solanaceae

The Solanaceae, or the nightshades, are a family of flowering plants that ranges from annual and perennial herbs to vines, lianas, epiphytes, shrubs, and trees, and includes a number of agricultural crops, medicinal plants, spices, weeds, and ornamentals.

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Somatic nervous system

The somatic nervous system (SNS) is made up of nerves that link the brain and spinal cord to voluntary or skeletal muscles that are under conscious control as well as to skin sensory receptors.

See Nicotine and Somatic nervous system

Somnolence

Somnolence (alternatively sleepiness or drowsiness) is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).

See Nicotine and Somnolence

Specific rotation

In chemistry, specific rotation is a property of a chiral chemical compound.

See Nicotine and Specific rotation

Splanchnic nerves

The splanchnic nerves are paired visceral nerves (nerves that contribute to the innervation of the internal organs), carrying fibers of the autonomic nervous system (visceral efferent fibers) as well as sensory fibers from the organs (visceral afferent fibers).

See Nicotine and Splanchnic nerves

Stillbirth

Stillbirth is typically defined as fetal death at or after 20 or 28 weeks of pregnancy, depending on the source.

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Stimulant

Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase the activity of the brain. Nicotine and stimulant are stimulants.

See Nicotine and Stimulant

Striatum

The striatum (striata) or corpus striatum is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia.

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Stroke

Stroke (also known as a cerebrovascular accident (CVA) or brain attack) is a medical condition in which poor blood flow to the brain causes cell death.

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Structural isomer

In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compound is another compound whose molecule has the same number of atoms of each element, but with logically distinct bonds between them.

See Nicotine and Structural isomer

Substance dependence

Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption of the drug.

See Nicotine and Substance dependence

Superman

Superman is a superhero who appears in American comic books published by DC Comics.

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Suppository

A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects.

See Nicotine and Suppository

Surgeon General of the United States

The surgeon general of the United States is the operational head of the United States Public Health Service Commissioned Corps (PHSCC) and thus the leading spokesperson on matters of public health in the federal government of the United States.

See Nicotine and Surgeon General of the United States

Sympathetic nervous system

The sympathetic nervous system (SNS) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous system and the enteric nervous system.

See Nicotine and Sympathetic nervous system

Sympatholytic

A sympatholytic (sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS).

See Nicotine and Sympatholytic

Sympathomimetic drug

Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of endogenous agonists of the sympathetic nervous system.

See Nicotine and Sympathomimetic drug

Syncope (medicine)

Syncope, commonly known as fainting or passing out, is a loss of consciousness and muscle strength characterized by a fast onset, short duration, and spontaneous recovery.

See Nicotine and Syncope (medicine)

Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

See Nicotine and Tachycardia

Tachypnea

Tachypnea, also spelt tachypnoea, is a respiratory rate greater than normal, resulting in abnormally rapid and shallow breathing.

See Nicotine and Tachypnea

Temporomandibular joint dysfunction

Temporomandibular joint dysfunction (TMD, TMJD) is an umbrella term covering pain and dysfunction of the muscles of mastication (the muscles that move the jaw) and the temporomandibular joints (the joints which connect the mandible to the skull).

See Nicotine and Temporomandibular joint dysfunction

Teratology

Teratology is the study of abnormalities of physiological development in organisms during their life span. Nicotine and Teratology are Teratogens.

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The New Yorker

The New Yorker is an American magazine featuring journalism, commentary, criticism, essays, fiction, satire, cartoons, and poetry.

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Theophylline

Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors.

See Nicotine and Theophylline

Tobacco

Tobacco is the common name of several plants in the genus Nicotiana of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. Nicotine and Tobacco are nicotinic agonists.

See Nicotine and Tobacco

Tobacco control

Tobacco control is a field of international public health science, policy and practice dedicated to addressing tobacco use and thereby reducing the morbidity and mortality it causes.

See Nicotine and Tobacco control

Tobacco-specific nitrosamines

Tobacco-specific nitrosamines (TSNAs) comprise one of the most important groups of carcinogens in tobacco products, particularly cigarettes (traditional and electronic) and fermented dipping snuff.

See Nicotine and Tobacco-specific nitrosamines

Tomato

The tomato is the edible berry of the plant Solanum lycopersicum, commonly known as the tomato plant.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Toxicology and Applied Pharmacology

Toxicology and Applied Pharmacology is a semi-monthly peer-reviewed scientific journal covering research pertaining to the action of chemicals, drugs, or natural products on animals or humans.

See Nicotine and Toxicology and Applied Pharmacology

Transdermal

Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.

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Transdermal patch

A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.

See Nicotine and Transdermal patch

Tremor

A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.

See Nicotine and Tremor

Tricyclic antidepressant

Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.

See Nicotine and Tricyclic antidepressant

Tumor promotion

Tumor promotion is a process in carcinogenesis by which various factors permit the descendants of a single initiated cell to survive and expand in number, i.e. to resist apoptosis and to undergo clonal growth.

See Nicotine and Tumor promotion

Type 2 diabetes

Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.

See Nicotine and Type 2 diabetes

Ultraviolet

Ultraviolet (UV) light is electromagnetic radiation of wavelengths of 10–400 nanometers, shorter than that of visible light, but longer than X-rays.

See Nicotine and Ultraviolet

Upper respiratory tract infection

An upper respiratory tract infection (URTI) is an illness caused by an acute infection, which involves the upper respiratory tract, including the nose, sinuses, pharynx, larynx or trachea.

See Nicotine and Upper respiratory tract infection

Urine

Urine is a liquid by-product of metabolism in humans and in many other animals.

See Nicotine and Urine

Urine flow rate

Urine flow rate or urinary flow rate is the volumetric flow rate of urine during urination.

See Nicotine and Urine flow rate

Uterus

The uterus (from Latin uterus,: uteri) or womb is the organ in the reproductive system of most female mammals, including humans, that accommodates the embryonic and fetal development of one or more embryos until birth.

See Nicotine and Uterus

Vapor pressure

Vapor pressure or equilibrium vapor pressure is the pressure exerted by a vapor in thermodynamic equilibrium with its condensed phases (solid or liquid) at a given temperature in a closed system.

See Nicotine and Vapor pressure

Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

See Nicotine and Vasoconstriction

Vasodilation

Vasodilation, also known as vasorelaxation, is the widening of blood vessels.

See Nicotine and Vasodilation

Ventral tegmental area

The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain.

See Nicotine and Ventral tegmental area

Water

Water is an inorganic compound with the chemical formula.

See Nicotine and Water

Weakness

Weakness is a symptom of many different medical conditions.

See Nicotine and Weakness

World War II

World War II or the Second World War (1 September 1939 – 2 September 1945) was a global conflict between two alliances: the Allies and the Axis powers.

See Nicotine and World War II

Xylometazoline

Xylometazoline, also spelled xylomethazoline, is a medication used to reduce symptoms of nasal congestion, allergic rhinitis, and sinusitis.

See Nicotine and Xylometazoline

Yerkes–Dodson law

The Yerkes–Dodson law is an empirical relationship between arousal and performance, originally developed by psychologists Robert M. Yerkes and John Dillingham Dodson in 1908.

See Nicotine and Yerkes–Dodson law

6-Chloronicotine

6-Chloronicotine is a drug which acts as an agonist at neural nicotinic acetylcholine receptors. Nicotine and 6-Chloronicotine are nicotinic agonists.

See Nicotine and 6-Chloronicotine

See also

Alkaloids found in Erythroxylum coca

Alkaloids found in Nicotiana

Plant toxin insecticides

Pregnane X receptor agonists

Pyridine alkaloids

Pyrrolidine alkaloids

References

[1] https://en.wikipedia.org/wiki/Nicotine

Also known as ATC code N07BA01, ATCvet code QN07BA01, ATCvet code QP53AX13, Biosynthesis of nicotine, Black Leaf, Black Leaf 40, Campbell's Nico-Soap, Destruxol Orchid Spray, Developmental effects of nicotine, EC 200-193-3, Emo-Nik, Flux Maag, Fumetobac, Mach-Nic, Niagara P.A. Dust, Nic-Sal, Nico-Dust, Nico-Fume, Nicocide, Nicoderm Cq, Nicorette Plus, Nicotene, Nicotin, Nicotine Addiction, Nicotine alkaloids, Nicotine sulfate, Nicotrol Inhaler, Nicotrol Ns, Nikotin, Nikotyna, Ortho N-4 Dust, Ortho N-5 Dust, Tendust, Tobacco addiction.

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