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Palmitoylation

Index Palmitoylation

Palmitoylation is the covalent attachment of fatty acids, such as palmitic acid, to cysteine and less frequently to serine and threonine residues of proteins, which are typically membrane proteins. [1]

39 relations: Acyl-protein thioesterase, Acylation, Acyltransferase, Cancer, Chemical synapse, Cysteine, Cytosol, Delta catenin, DHHC domain, DLG4, Endothelium, Enzyme, Fatty acid, GABAergic, Gephyrin, Gs alpha subunit, Hemagglutinin, HRAS, Influenza, Lipid bilayer, Lysosome, Mammal, Meta-analysis, Myristoylation, Nervous system, Neurotransmitter, Nitric oxide synthase, Palmitic acid, Palmitoleic acid, Palmitoyl protein thioesterase, Prenylation, Protein–protein interaction, Serine, SNAP25, SNARE (protein), Synapse, Thioester, Threonine, Wnt signaling pathway.

Acyl-protein thioesterase

Acyl-protein thioesterases are enzymes that cleave off lipid modifications on proteins, located on the sulfur atom of cysteine residues linked via a thioester bond.

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Acylation

In chemistry, acylation (rarely, but more formally: alkanoylation) is the process of adding an acyl group to a compound.

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Acyltransferase

Acyltransferase is a type of transferase enzyme that acts upon acyl groups.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.

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Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Cytosol

The cytosol, also known as intracellular fluid (ICF) or cytoplasmic matrix, is the liquid found inside cells.

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Delta catenin

Delta-1-catenin and Delta-2-catenin are members of a subfamily of proteins with ten Armadillo-repeats.

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DHHC domain

In molecular biology the DHHC domain is a protein domain that acts as an enzyme, which adds a palmitoyl chemical group to proteins in order to anchor them to cell membranes.

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DLG4

PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Fatty acid

In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.

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GABAergic

GABAergic means "pertaining to or affecting the neurotransmitter GABA".

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Gephyrin

Gephyrin is a protein that in humans is encoded by the GPHN gene.

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Gs alpha subunit

The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.

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Hemagglutinin

Hemagglutinin or haemagglutinin (British English)p refers to a substance that causes red blood cells (RBCs) to agglutinate.

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HRAS

GTPase HRas also known as transforming protein p21 is an enzyme that in humans is encoded by the HRAS gene.

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Influenza

Influenza, commonly known as "the flu", is an infectious disease caused by an influenza virus.

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Lipid bilayer

The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.

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Lysosome

A lysosome is a membrane-bound organelle found in nearly all animal cells.

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Mammal

Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.

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Meta-analysis

A meta-analysis is a statistical analysis that combines the results of multiple scientific studies.

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Myristoylation

Myristoylation is a lipidation modification where a myristoyl group, derived from myristic acid, is covalently attached by an amide bond to the alpha-amino group of an N-terminal glycine residue.

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Nervous system

The nervous system is the part of an animal that coordinates its actions by transmitting signals to and from different parts of its body.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Nitric oxide synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.

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Palmitic acid

Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms.

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Palmitoleic acid

Palmitoleic acid, or (9Z)-hexadec-9-enoic acid, is an omega-7 monounsaturated fatty acid with the formula CH3(CH2)5CH.

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Palmitoyl protein thioesterase

Palmitoyl protein thioesterases are enzymes that remove thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation.

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Prenylation

Prenylation (also known as isoprenylation or lipidation) is the addition of hydrophobic molecules to a protein or chemical compound.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Serine

Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.

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SNAP25

Synaptosomal-associated protein 25 (SNAP-25) is a t-SNARE protein that is encoded by the SNAP25 gene in humans.

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SNARE (protein)

SNARE proteins (an acronym derived from "SNAP (Soluble NSF(N-ethylmaleimide-sensitive factor) Attachment Protein) REceptor)" are a large protein complex consisting of at least 24 members in yeasts and more than 60 members in mammalian cells.

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Synapse

In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target efferent cell.

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Thioester

In chemistry thioesters are compounds with the functional group R–S–CO–R'.

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Threonine

Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

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Wnt signaling pathway

The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors.

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Redirects here:

Palmitoyl, Palmitoyl chain, Palmitoyl chains, Palmitoyl group, Palmitoylated, Palmitoylations, S-palmitoylation.

References

[1] https://en.wikipedia.org/wiki/Palmitoylation

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