71 relations: Acute lymphoblastic leukemia, Acute pancreatitis, Acute promyelocytic leukemia, Adverse drug reaction, Allopurinol, Antileukemic drug, Antimetabolite, ATC code L01, Autoimmune pancreatitis, Azathioprine, C5H4N4S, California Proposition 65 list of chemicals, Cancer biomarker, Chemotherapy, Chemotherapy regimen, Crohn's disease, DAM (chemotherapy), Emil J. Freireich, Febuxostat, George H. Hitchings, Gertrude B. Elion, GlaxoSmithKline, Glossary of chemical formulas, Grapefruit–drug interactions, History of cancer chemotherapy, Idiopathic pulmonary haemosiderosis, Imidazole, Immunosuppressive drug, Index of oncology articles, Inflammatory bowel disease, James F. Holland, Janis Babson, Joseph H. Burchenal, Leukemia, List of antineoplastic agents, List of chemotherapeutic agents, List of drugs: 1-9, List of drugs: Mep-Mes, List of drugs: Ps-Pz, List of IARC Group 3 carcinogens, List of medical abbreviations: 0–9, List of MeSH codes (D02), List of MeSH codes (D03), Management of Crohn's disease, Management of ulcerative colitis, Megaloblastic anemia, Memorial Sloan Kettering Cancer Center, National Cancer Institute, Nucleic acid analogue, Pellagra, ..., Pharmacogenetics, Pharmacogenomics, Prodrug, Purine analogue, René Küss, Scleroderma, Thiol, Thiopurine, Thiopurine methyltransferase, Thiouric acid, Timeline of cancer treatment development, Timeline of leukemia, TNF inhibitor, Trimethoprim/sulfamethoxazole, Tuckahoe (village), New York, VAMP regimen, WHO Model List of Essential Medicines, WHO Model List of Essential Medicines for Children, Xanthine oxidase, Zidovudine, 7+3 (chemotherapy). Expand index (21 more) »
Acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.
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Acute pancreatitis
Acute pancreatitis is a sudden inflammation of the pancreas (pancreatitis).
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Acute promyelocytic leukemia
Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells.
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Adverse drug reaction
An adverse drug reaction (ADR) is an injury caused by taking a medication.
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Allopurinol
Allopurinol, sold under the brand name Zyloprim among others, is a medication used to decrease high blood uric acid levels.
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Antileukemic drug
Antileukemic drugs, anticancer drugs that are used to treat one or more types of leukemia, include.
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Antimetabolite
An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.
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ATC code L01
L01.
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Autoimmune pancreatitis
Autoimmune pancreatitis (AIP) is an increasingly recognized type of chronic pancreatitis that can be difficult to distinguish from pancreatic carcinoma but which responds to treatment with corticosteroids, particularly prednisone.
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Azathioprine
Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication.
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C5H4N4S
The molecular formula C5H4N4S (molar mass: 152.18 g/mol) may refer to.
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California Proposition 65 list of chemicals
The following is a list of chemicals published as a requirement of Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California Proposition 65, that are "known to the state to cause cancer or reproductive toxicity" as of December 29, 2017.
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Cancer biomarker
A cancer biomarker refers to a substance or process that is indicative of the presence of cancer in the body.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chemotherapy regimen
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.
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Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.
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DAM (chemotherapy)
DAM in the context of chemotherapy is an acronym that means a chemotherapy regimen most often used as an induction regimen in acute myelogenous leukemia, usually for those who are refractory to the standard "7+3" induction regimen or who has relapsed.
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Emil J. Freireich
Emil Jay Freireich (born 1927)https://history.nih.gov/archives/downloads/freireich.pdf is a cancer biologist recognized as a pioneer in the treatment of cancer and use of chemotherapy.
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Febuxostat
Febuxostat, sold under the brand names Uloric among others, is a medication used in the treatment of chronic gout and hyperuricemia.
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George H. Hitchings
George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American doctor who shared the 1988 Nobel Prize in Physiology or Medicine with Sir James Black and Gertrude Elion "for their discoveries of important principles for drug treatment," Hitchings specifically for his work on chemotherapy.
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Gertrude B. Elion
Gertrude Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black.
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GlaxoSmithKline
GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.
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Glossary of chemical formulas
This is a list of common chemical compounds with chemical formulas and CAS numbers, indexed by formula.
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Grapefruit–drug interactions
Some fruit juices and fruits can interact with numerous drugs, in many cases causing adverse effects.
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History of cancer chemotherapy
The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs.
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Idiopathic pulmonary haemosiderosis
Idiopathic pulmonary haemosiderosis (or idiopathic pulmonary hemosiderosis; IPH) is a lung disease of unknown cause that is characterized by alveolar capillary bleeding and accumulation of haemosiderin in the lungs.
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Imidazole
Imidazole is an organic compound with the formula C3N2H4.
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Immunosuppressive drug
Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system.
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Index of oncology articles
This is a list of terms related to oncology.
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Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
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James F. Holland
James Frederick Holland (May 16, 1925 – March 22, 2018) was an American physician and Distinguished Professor of Neoplastic Diseases at the Icahn School of Medicine at Mount Sinai in New York.
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Janis Babson
Janis Anne Babson (September 9, 1950 – May 12, 1961) was a Canadian girl who received posthumous acclaim with the donation of her corneas for transplant after her death from leukemia at the age of 10.
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Joseph H. Burchenal
Joseph Holland Burchenal (December 21, 1912 – March 8, 2006) was an American oncologist, and a winner of the 1972 Albert Lasker Award for Medical Research for his work on developing a chemotherapy for Burkitt's lymphoma.
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Leukemia
Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
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List of antineoplastic agents
This is a list of antineoplastic agents used to treat cancer.
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List of chemotherapeutic agents
This is a list of chemotherapeutic agents (also known as cytotoxic agents) that are known to be of use in chemotherapy for cancer.
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List of drugs: 1-9
No description.
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List of drugs: Mep-Mes
No description.
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List of drugs: Ps-Pz
No description.
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List of IARC Group 3 carcinogens
Substances, mixtures and exposure circumstances in this list have been classified by the International Agency for Research on Cancer (IARC) as Group 3: The agent (mixture or exposure circumstance) is not classifiable as to its carcinogenicity to humans. This category is used most commonly for agents, mixtures and exposure circumstances for which the evidence of carcinogenicity is inadequate in humans and inadequate or limited in experimental animals.
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List of medical abbreviations: 0–9
Category:Lists of medical abbreviations.
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List of MeSH codes (D02)
This is the fourth part of the list of the "D" codes for MeSH.
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List of MeSH codes (D03)
This is the fourth part of the list of the "D" codes for MeSH.
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Management of Crohn's disease
Management of Crohn's disease involves first treating the acute symptoms of the disease, then maintaining remission.
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Management of ulcerative colitis
Management of ulcerative colitis involves first treating the acute symptoms of the disease, then maintaining remission.
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Megaloblastic anemia
Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of macrocytic classification) that results from inhibition of DNA synthesis during red blood cell production.
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Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in New York City, founded in 1884 as the New York Cancer Hospital.
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National Cancer Institute
The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.
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Nucleic acid analogue
Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.
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Pellagra
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3).
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Pharmacogenetics
Pharmacogenetics is the study of inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects.
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Pharmacogenomics
Pharmacogenomics is the study of the role of the genome in drug response.
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Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
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Purine analogue
Purine analogues are antimetabolites that mimic the structure of metabolic purines.
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René Küss
René Küss (3 May 1913 – 2006) was a French pioneering urologist and transplant surgeon who made ground-breaking contributions in renal tract surgery and kidney transplantation with the establishment of transplant programs.
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Scleroderma
Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs.
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Thiol
Thiol is an organosulfur compound that contains a carbon-bonded sulfhydryl (R–SH) group (where R represents an alkyl or other organic substituent).
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Thiopurine
The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients.
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Thiopurine methyltransferase
Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene.
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Thiouric acid
Thiouric acid, more accurately called 6-thiouric acid, is a main inactive metabolite of the immunosuppressive drugs azathioprine, mercaptopurine and tioguanine.
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Timeline of cancer treatment development
This is a historical timeline of the development and progress of cancer treatments, which includes time of discovery, progress, and approval of the treatments.
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Timeline of leukemia
This is a timeline of leukemia, describing especially major discoveries and advances in treatment against the disease.
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TNF inhibitor
A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.
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Trimethoprim/sulfamethoxazole
Trimethoprim/sulfamethoxazole (TMP/SMX), also known as co-trimoxazole among other names, is an antibiotic used to treat a variety of bacterial infections.
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Tuckahoe (village), New York
Tuckahoe is a village in the town of Eastchester in Westchester County, New York, United States.
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VAMP regimen
VAMP regimen or VAMP chemotherapy is a four-drug combination chemotherapy regimen, used today in the treatment of Hodgkin lymphoma.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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WHO Model List of Essential Medicines for Children
The WHO Model List of Essential Medicines for Children is a list, proposed by the World Health Organization (WHO), of the most effective and safe medicines for use in children up to 12 years of age needed to meet the most important needs in a basic health-care system.
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Xanthine oxidase
Xanthine oxidase (XO, sometimes XAO) is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species.
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Zidovudine
Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS.
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7+3 (chemotherapy)
"7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always the case).
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Redirects here:
6 MP, 6 mercaptopurine, 6-MP, 6-Mercaptopurine, 6-mercaptopurine, 6MP, ATC code L01BB02, ATCvet code QL01BB02, Ismipur, Leukerin, Leupurin, Mercaleukim, Mercaleukin, Puri-Nethol, Purimethol, Purinethiol, Purinethol, Purinetol.
References
[1] https://en.wikipedia.org/wiki/Mercaptopurine