Nicotinic acid adenine dinucleotide phosphate

Nicotinic acid adenine dinucleotide phosphate, (NAADP), is a Ca2+-mobilizing second messenger synthesised in response to extracellular stimuli. ^[1]

4 relations: Antony Galione, Calcium channel, Cyclic ADP-ribose, Two-pore channel.

Antony Galione

Antony Giuseppe Galione (born 1963) is professor of Pharmacology and Wellcome Trust Senior Investigator in the Department of Pharmacology at the University of Oxford.

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Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions.

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Cyclic ADP Ribose, frequently abbreviated as cADPR, is a cyclic adenine nucleotide (like cAMP) with two phosphate groups present on 5' OH of the adenosine (like ADP), further connected to another ribose at the 5' position, which, in turn, closes the cycle by glycosidic bonding to the nitrogen 1 (N1) of the same adenine base (whose position N9 has the glycosidic bond to the other ribose).

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Two-pore channel

Two-pore channels (TPCs) are eukaryotic intracellular voltage-gated and ligand gated cation selective ion channels.

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NAADP, Nicotinic Acid Adenine Dinucleotide Phosphate.

References

[1] https://en.wikipedia.org/wiki/Nicotinic_acid_adenine_dinucleotide_phosphate

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