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S-adenosylmethionine synthetase enzyme

Index S-adenosylmethionine synthetase enzyme

S-adenosylmethionine synthetase (also known as methionine adenosyltransferase (MAT)) is an enzyme that creates S-adenosylmethionine (a.k.a. AdoMet, SAM or SAMe) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy). [1]

14 relations: Biological effects of radiation on the epigenome, Enzyme, EZH2, Homocysteine, Hypermethioninemia, List of EC numbers (EC 2), List of MeSH codes (D08), Methionine, Mevastatin, Riboswitch, S-Adenosyl methionine, SAM-Chlorobi RNA motif, SAM-SAH riboswitch, 1-aminocyclopropane-1-carboxylate synthase.

Biological effects of radiation on the epigenome

Ionizing radiation can cause biological effects which are passed on to offspring through the epigenome.

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Enzyme

Enzymes are macromolecular biological catalysts.

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EZH2

Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression.

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Homocysteine

Homocysteine is a non-proteinogenic α-amino acid.

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Hypermethioninemia

Hypermethioninemia is an excess of the amino acid methionine, in the blood.

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List of EC numbers (EC 2)

This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of MeSH codes (D08)

This is the fourth part of the list of the "D" codes for MeSH.

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Methionine

Methionine (symbol Met or M) is an essential amino acid in humans.

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Mevastatin

Mevastatin (compactin, ML-236B) is a hypolipidemic agent that belongs to the statins class.

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Riboswitch

In molecular biology, a riboswitch is a regulatory segment of a messenger RNA molecule that binds a small molecule, resulting in a change in production of the proteins encoded by the mRNA.

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S-Adenosyl methionine

S-Adenosyl methionineSAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation.

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SAM-Chlorobi RNA motif

The SAM-Chlorobi RNA motif is a conserved RNA structure that was identified by bioinformatics.

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SAM-SAH riboswitch

The SAM-SAH riboswitch is a conserved RNA structure in certain bacteria that binds ''S''-adenosylmethionine (SAM) and ''S''-adenosylhomocysteine (SAH) and is therefore presumed to be a riboswitch.

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1-aminocyclopropane-1-carboxylate synthase

Aminocyclopropane-1-carboxylic acid synthase (ACC synthase, ACS) is an enzyme that catalyzes the synthesis of 1-Aminocyclopropane-1-carboxylic acid (ACC), a precursor for ethylene, from S-Adenosyl methionine (AdoMet, SAM), an intermediate in the Yang cycle and activated methyl cycle and a useful molecule for methyl transfer.

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Redirects here:

ATP:L-metionin S-adenoziltransferase, EC 2.5.1.6, Methionine adenosyltransferase, S-adenosyl-methionine synthetase, S-adenosylmethionine synthetase, S-adenosylmethionine synthetase C terminal domain.

References

[1] https://en.wikipedia.org/wiki/S-adenosylmethionine_synthetase_enzyme

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