Interstate 405 (usually pronounced four-oh-five), also known as I-405 or colloquially as "the 405", is a major north–south Interstate Highway in Southern California.
Interstate 405 (I-405, also known as the Stadium Freeway No. 61) is a short Interstate Highway in Portland, Oregon.
Interstate 405 (I-405) is a north–south auxiliary Interstate Highway in the U.S. state of Washington.
King's Highway 405, also known as Highway 405 and the General Brock Parkway, is a 400-Series Highway in the Canadian province of Ontario connecting the Queen Elizabeth Way (QEW) near St. Catharines with the Lewiston–Queenston Bridge in the village of Queenston.