70 relations: Adrenaline, Agonist, Alpha-1 adrenergic receptor, Angiogenesis, Angiogenesis inhibitor, Antioxidant, Aromatic sulfonation, Biosynthesis, Biotransformation, Brain, Breast, Cancer, Carcinogenesis, Catechol, Catechol estrogen, Catechol-O-methyltransferase, Catecholamine, Cell (biology), CYP1A2, CYP3A4, Cytochrome P450, DNA, Dopamine, Dopamine receptor D2, Endogeny (biology), Enzyme, Enzyme inhibitor, Estradiol, Estriol, Estrogen, Estrogen receptor, Estrogen receptor alpha, Estrogen receptor beta, Estrone, Excretion, Glucuronidation, GPER, Hydroxylation, Intravenous therapy, Intrinsic activity, Kidney, Ligand (biochemistry), Liver, Metabolic intermediate, Metabolism, Metabolite, Methoxy group, Methylation, Molar concentration, Neoplasm, ..., Norepinephrine, Pituitary gland, Placenta, Prodrug, Quinone, Radical (chemistry), Receptor antagonist, Redox, Selective estrogen receptor modulator, Semiquinone, Spiperone, Steroid, Structural isomer, Superoxide, Tyrosine hydroxylase, Urine, Uterus, 2-Hydroxyestrone, 2-Methoxyestradiol, 4-Hydroxyestradiol. Expand index (20 more) »
Adrenaline
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
New!!: 2-Hydroxyestradiol and Adrenaline · See more »
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
New!!: 2-Hydroxyestradiol and Agonist · See more »
Alpha-1 adrenergic receptor
The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein.
New!!: 2-Hydroxyestradiol and Alpha-1 adrenergic receptor · See more »
Angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.
New!!: 2-Hydroxyestradiol and Angiogenesis · See more »
Angiogenesis inhibitor
An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).
New!!: 2-Hydroxyestradiol and Angiogenesis inhibitor · See more »
Antioxidant
Antioxidants are molecules that inhibit the oxidation of other molecules.
New!!: 2-Hydroxyestradiol and Antioxidant · See more »
Aromatic sulfonation
Aromatic sulfonation is an organic reaction in which a hydrogen atom on an arene is replaced by a sulfonic acid functional group in an electrophilic aromatic substitution.
New!!: 2-Hydroxyestradiol and Aromatic sulfonation · See more »
Biosynthesis
Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.
New!!: 2-Hydroxyestradiol and Biosynthesis · See more »
Biotransformation
Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound.
New!!: 2-Hydroxyestradiol and Biotransformation · See more »
Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
New!!: 2-Hydroxyestradiol and Brain · See more »
Breast
The breast is one of two prominences located on the upper ventral region of the torso of primates.
New!!: 2-Hydroxyestradiol and Breast · See more »
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
New!!: 2-Hydroxyestradiol and Cancer · See more »
Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
New!!: 2-Hydroxyestradiol and Carcinogenesis · See more »
Catechol
Catechol, also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula C6H4(OH)2.
New!!: 2-Hydroxyestradiol and Catechol · See more »
Catechol estrogen
A catechol estrogen is a steroidal estrogen that contains catechol (1,2-dihydroxybenzene) within its structure.
New!!: 2-Hydroxyestradiol and Catechol estrogen · See more »
Catechol-O-methyltransferase
Catechol-O-methyltransferase (COMT) is one of several enzymes that degrade catecholamines (such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure.
New!!: 2-Hydroxyestradiol and Catechol-O-methyltransferase · See more »
Catecholamine
A catecholamine (CA) is a monoamine, an organic compound that has a catechol (benzene with two hydroxyl side groups at carbons 1 and 2) and a side-chain amine.
New!!: 2-Hydroxyestradiol and Catecholamine · See more »
Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
New!!: 2-Hydroxyestradiol and Cell (biology) · See more »
CYP1A2
Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.
New!!: 2-Hydroxyestradiol and CYP1A2 · See more »
CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
New!!: 2-Hydroxyestradiol and CYP3A4 · See more »
Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
New!!: 2-Hydroxyestradiol and Cytochrome P450 · See more »
DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
New!!: 2-Hydroxyestradiol and DNA · See more »
Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
New!!: 2-Hydroxyestradiol and Dopamine · See more »
Dopamine receptor D2
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.
New!!: 2-Hydroxyestradiol and Dopamine receptor D2 · See more »
Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
New!!: 2-Hydroxyestradiol and Endogeny (biology) · See more »
Enzyme
Enzymes are macromolecular biological catalysts.
New!!: 2-Hydroxyestradiol and Enzyme · See more »
Enzyme inhibitor
4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
New!!: 2-Hydroxyestradiol and Enzyme inhibitor · See more »
Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
New!!: 2-Hydroxyestradiol and Estradiol · See more »
Estriol
Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone.
New!!: 2-Hydroxyestradiol and Estriol · See more »
Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
New!!: 2-Hydroxyestradiol and Estrogen · See more »
Estrogen receptor
Estrogen receptors (ERs) are a group of proteins found inside cells.
New!!: 2-Hydroxyestradiol and Estrogen receptor · See more »
Estrogen receptor alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.
New!!: 2-Hydroxyestradiol and Estrogen receptor alpha · See more »
Estrogen receptor beta
Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.
New!!: 2-Hydroxyestradiol and Estrogen receptor beta · See more »
Estrone
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone.
New!!: 2-Hydroxyestradiol and Estrone · See more »
Excretion
Excretion is the process by which metabolic waste is eliminated from an organism.
New!!: 2-Hydroxyestradiol and Excretion · See more »
Glucuronidation
Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.
New!!: 2-Hydroxyestradiol and Glucuronidation · See more »
GPER
G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene.
New!!: 2-Hydroxyestradiol and GPER · See more »
Hydroxylation
Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.
New!!: 2-Hydroxyestradiol and Hydroxylation · See more »
Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
New!!: 2-Hydroxyestradiol and Intravenous therapy · See more »
Intrinsic activity
Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.
New!!: 2-Hydroxyestradiol and Intrinsic activity · See more »
Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
New!!: 2-Hydroxyestradiol and Kidney · See more »
Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
New!!: 2-Hydroxyestradiol and Ligand (biochemistry) · See more »
Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
New!!: 2-Hydroxyestradiol and Liver · See more »
Metabolic intermediate
Metabolic intermediates are molecules which are the precursors or metabolites of biologically significant molecules.
New!!: 2-Hydroxyestradiol and Metabolic intermediate · See more »
Metabolism
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
New!!: 2-Hydroxyestradiol and Metabolism · See more »
Metabolite
A metabolite is the intermediate end product of metabolism.
New!!: 2-Hydroxyestradiol and Metabolite · See more »
Methoxy group
A methoxy group is the functional group consisting of a methyl group bound to oxygen.
New!!: 2-Hydroxyestradiol and Methoxy group · See more »
Methylation
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.
New!!: 2-Hydroxyestradiol and Methylation · See more »
Molar concentration
Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.
New!!: 2-Hydroxyestradiol and Molar concentration · See more »
Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
New!!: 2-Hydroxyestradiol and Neoplasm · See more »
Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
New!!: 2-Hydroxyestradiol and Norepinephrine · See more »
Pituitary gland
An explanation of the development of the pituitary gland (Hypophysis cerebri) & the congenital anomalies. In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing in humans.
New!!: 2-Hydroxyestradiol and Pituitary gland · See more »
Placenta
The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, thermo-regulation, waste elimination, and gas exchange via the mother's blood supply; to fight against internal infection; and to produce hormones which support pregnancy.
New!!: 2-Hydroxyestradiol and Placenta · See more »
Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
New!!: 2-Hydroxyestradiol and Prodrug · See more »
Quinone
The quinones are a class of organic compounds that are formally "derived from aromatic compounds by conversion of an even number of –CH.
New!!: 2-Hydroxyestradiol and Quinone · See more »
Radical (chemistry)
In chemistry, a radical (more precisely, a free radical) is an atom, molecule, or ion that has an unpaired valence electron.
New!!: 2-Hydroxyestradiol and Radical (chemistry) · See more »
Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
New!!: 2-Hydroxyestradiol and Receptor antagonist · See more »
Redox
Redox (short for reduction–oxidation reaction) (pronunciation: or) is a chemical reaction in which the oxidation states of atoms are changed.
New!!: 2-Hydroxyestradiol and Redox · See more »
Selective estrogen receptor modulator
Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).
New!!: 2-Hydroxyestradiol and Selective estrogen receptor modulator · See more »
Semiquinone
Semiquinone (or ubisemiquinone) is a free radical resulting from the removal of one hydrogen atom with its electron during the process of dehydrogenation of a hydroquinone, such as hydroquinone itself or catechol, to a quinone or alternatively the addition of a single H atom to a quinone.
New!!: 2-Hydroxyestradiol and Semiquinone · See more »
Spiperone
Spiperone (Spiroperidol; brand name: Spiropitan (JP)) is a typical antipsychotic and research chemical belonging to the butyrophenone chemical class.
New!!: 2-Hydroxyestradiol and Spiperone · See more »
Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
New!!: 2-Hydroxyestradiol and Steroid · See more »
Structural isomer
Structural isomerism, or constitutional isomerism (per IUPAC), is a form of isomerism in which molecules with the same molecular formula have different bonding patterns and atomic organization, as opposed to stereoisomerism, in which molecular bonds are always in the same order and only spatial arrangement differs.
New!!: 2-Hydroxyestradiol and Structural isomer · See more »
Superoxide
A superoxide is a compound that contains the superoxide anion, which has the chemical formula.
New!!: 2-Hydroxyestradiol and Superoxide · See more »
Tyrosine hydroxylase
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA).
New!!: 2-Hydroxyestradiol and Tyrosine hydroxylase · See more »
Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
New!!: 2-Hydroxyestradiol and Urine · See more »
Uterus
The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.
New!!: 2-Hydroxyestradiol and Uterus · See more »
2-Hydroxyestrone
2-Hydroxyestrone (2-OHE1), also known as estra-1,3,5(10)-trien-2,3-diol-17-one, is an endogenous, naturally occurring catechol estrogen and a major metabolite of estrone and estradiol.
New!!: 2-Hydroxyestradiol and 2-Hydroxyestrone · See more »
2-Methoxyestradiol
2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol.
New!!: 2-Hydroxyestradiol and 2-Methoxyestradiol · See more »
4-Hydroxyestradiol
4-Hydroxyestradiol (4-OHE2), also known as estra-1,3,5(10)-triene-3,4,17β-triol, is an endogenous, naturally occurring catechol estrogen and a minor metabolite of estradiol.
New!!: 2-Hydroxyestradiol and 4-Hydroxyestradiol · See more »
Redirects here:
References
[1] https://en.wikipedia.org/wiki/2-Hydroxyestradiol