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63 relations: ACTH receptor, Addison's disease, Adenylyl cyclase, Adrenal cortex, Adrenal gland, Adrenal insufficiency, Adrenaline, Adrenocorticotropic hormone (medication), Adrenoleukodystrophy, Amino acid, Anterior pituitary, Cholesterol, Cholesterol side-chain cleavage enzyme, Circadian rhythm, Congenital adrenal hyperplasia, Corticorelin, Corticotropic cell, Corticotropin-releasing hormone, Cortisol, Cushing's syndrome, Cyclic adenosine monophosphate, David Landsborough Thomson, Dexamethasone suppression test, Dopamine beta-hydroxylase, Endopeptidase, Epileptic spasms, Evelyn M. Anderson, G protein–coupled receptor, Glucocorticoid, Glycosylation, Half-life, Hyperpigmentation, Hypopituitarism, Hypothalamic–pituitary–adrenal axis, Hypothalamus, James Collip, Lipoprotein, Melanin, Melanocortin receptor, Melanocyte-stimulating hormone, Nelson's syndrome, Norepinephrine, Osteoblast, Peptide, Phosphorylation, Pituitary disease, Pituitary gland, Post-translational modification, Postorgasmic illness syndrome, Proopiomelanocortin, ..., Protein kinase A, Residue (chemistry), Small-cell carcinoma, The Lancet, Time (magazine), Transcription (biology), Translation (biology), Tropic hormone, Tyrosine hydroxylase, Unified atomic mass unit, University of Pittsburgh, Vascular endothelial growth factor, Zona fasciculata. Expand index (13 more) »
ACTH receptor
The adrenocorticotropic hormone receptor or ACTH receptor also known as the melanocortin receptor 2 or MC2 receptor is a type of melanocortin receptor (type 2) which is specific for ACTH.
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Addison's disease
Addison's disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones.
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Adenylyl cyclase
Adenylyl cyclase (also commonly known as adenyl cyclase and adenylate cyclase, abbreviated AC) is an enzyme with key regulatory roles in essentially all cells.
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Adrenal cortex
Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, such as aldosterone and cortisol, respectively.
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Adrenal gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
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Adrenal insufficiency
Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.
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Adrenaline
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
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Adrenocorticotropic hormone (medication)
Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test.
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Adrenoleukodystrophy
Adrenoleukodystrophy is a disease linked to the X chromosome.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Anterior pituitary
A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).
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Cholesterol
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.
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Cholesterol side-chain cleavage enzyme
Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage.
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Circadian rhythm
A circadian rhythm is any biological process that displays an endogenous, entrainable oscillation of about 24 hours.
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Congenital adrenal hyperplasia
Congenital adrenal hyperplasia (CAH) are any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands (steroidogenesis).
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Corticorelin
Corticorelin (INN) is a diagnostic agent.
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Corticotropic cell
Corticotropes (or corticotrophs) are basophilic cells in the anterior pituitary that produce melanocyte-stimulating hormone, adrenocorticotropic hormone (ACTH) and lipotropin.
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Corticotropin-releasing hormone
Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in the stress response.
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Cortisol
Cortisol is a steroid hormone, in the glucocorticoid class of hormones.
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Cushing's syndrome
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to cortisol.
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Cyclic adenosine monophosphate
Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes.
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David Landsborough Thomson
David Landsborough Thomson F.R.S.C., (1901 - 1964) was a Canadian biochemist, best known for the co-discovery of Adrenocorticotropic hormone (adreno-cortical thyroid hormone or ACTH) and as the vice-principal of McGill University.
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Dexamethasone suppression test
The dexamethasone suppression test (DST) is used to assess adrenal gland function by measuring how cortisol levels change in response to an injection of dexamethasone.
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Dopamine beta-hydroxylase
Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme that in humans is encoded by the DBH gene.
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Endopeptidase
Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids.
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Epileptic spasms
Epileptic spasms, also known as infantile spasms, juvenile spasms, or West syndrome is an uncommon-to-rare epileptic disorder in infants, children and adults.
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Evelyn M. Anderson
Evelyn M. Anderson (March 20, 1899 – June 8, 1985) was an American physiologist and biochemist, most known for her co-discovery of Adrenocorticotropic hormone (adreno-cortical thyroid hormone or ACTH) in 1934.
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G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
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Glucocorticoid
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
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Glycosylation
Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).
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Half-life
Half-life (symbol t1⁄2) is the time required for a quantity to reduce to half its initial value.
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Hyperpigmentation
Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin.
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Hypopituitarism
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain.
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Hypothalamic–pituitary–adrenal axis
The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus, the pituitary gland (a pea-shaped structure located below the thalamus), and the adrenal (also called "suprarenal") glands (small, conical organs on top of the kidneys).
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Hypothalamus
The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.
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James Collip
James Bertram Collip, (November 20, 1892 – June 19, 1965) was a Candadian biochemist who was part of the Toronto group which isolated insulin.
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Lipoprotein
A lipoprotein is a biochemical assembly whose purpose is to transport hydrophobic lipid (a.k.a. fat) molecules in water, as in blood or extracellular fluid.
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Melanin
Melanin (from μέλας melas, "black, dark") is a broad term for a group of natural pigments found in most organisms.
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Melanocortin receptor
Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors.
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Melanocyte-stimulating hormone
The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary gland.
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Nelson's syndrome
Nelson's syndrome is a rare disorder and occurs in patients who have had both adrenal glands removed owing to Cushing's disease.
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Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
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Osteoblast
Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize bone.
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Peptide
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Pituitary disease
A pituitary disease is a disorder primarily affecting the pituitary gland.
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Pituitary gland
An explanation of the development of the pituitary gland (Hypophysis cerebri) & the congenital anomalies. In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing in humans.
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Post-translational modification
Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein biosynthesis.
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Postorgasmic illness syndrome
Postorgasmic illness syndrome (POIS) is a syndrome in which men have chronic physical and cognitive symptoms immediately following ejaculation in the absence of a local genital reaction.
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Proopiomelanocortin
Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues.
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Protein kinase A
In cell biology, protein kinase A (PKANot to be confused with pKa, the symbol for the acid dissociation constant.) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP).
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Residue (chemistry)
In chemistry residue is whatever remains or acts as a contaminant after a given class of events.
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Small-cell carcinoma
Small-cell carcinoma (also known as "small-cell lung cancer", or "oat-cell carcinoma") is a type of highly malignant cancer that most commonly arises within the lung, although it can occasionally arise in other body sites, such as the cervix, prostate, and gastrointestinal tract.
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The Lancet
The Lancet is a weekly peer-reviewed general medical journal.
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Time (magazine)
Time is an American weekly news magazine and news website published in New York City.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Translation (biology)
In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.
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Tropic hormone
Tropic hormones are hormones that have other endocrine glands as their target.
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Tyrosine hydroxylase
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA).
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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University of Pittsburgh
The University of Pittsburgh (commonly referred to as Pitt) is a state-related research university located in Pittsburgh, Pennsylvania.
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Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.
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Zona fasciculata
The zona fasciculata constitutes the middle and also the widest zone of the adrenal cortex, sitting directly beneath the zona glomerulosa.
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Redirects here:
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References
[1] https://en.wikipedia.org/wiki/Adrenocorticotropic_hormone
