Faster access than browser!
152 relations: Acetylcholine, Adderall, Adenylyl cyclase, Adipose tissue, Adrenal medulla, Adrenaline, Adrenergic receptor, Agmatine, Agonist, Allosteric regulation, Alpha blocker, Alpha-1 adrenergic receptor, Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Analgesic, Anesthesia, Antihypertensive drug, Apraclonidine, Aripiprazole, Artery, Asenapine, Atipamezole, Attention deficit hyperactivity disorder, Autoreceptor, Beta-2 adrenergic receptor, Brainstem, Brimonidine, BRL-44408, Cannabigerol, Cannabinoid receptor type 1, Catecholamine, Central nervous system, Cerebellum, Cerebral cortex, Chemical synapse, Cirazoline, Clonidine, Clozapine, Coronary arteries, Cramp, Cyclic adenosine monophosphate, CYP1A2, CYP2D6, CYP3A4, Department of Health (Australia), Detomidine, ..., Dexmedetomidine, Efaroxan, Epidural administration, European Medicines Agency, G protein, G protein–coupled receptor, Gastrointestinal tract, Gi alpha subunit, Glucagon, Glycogen phosphorylase, Guanabenz, Guanfacine, Heart, Heterotrimeric G protein, Hippocampus, Hypertension, Hypotension, Hypothalamus, Idazoxan, Imidazoline receptor, Imiloxan, Insulin, Intensive care unit, Intravenous therapy, Lipolysis, Locus coeruleus, Lofexidine, Lurasidone, Medetomidine, Medulla oblongata, Melperone, Methamphetamine, Methylphenidate, Mianserin, Midbrain, Mirtazapine, Mivazerol, Neurotransmission, Neurotransmitter, Nicotinic acetylcholine receptor, Nitric oxide synthase, NMDA receptor antagonist, Norepinephrine, Olanzapine, Opioid use disorder, Oxymetazoline, Paliperidone, Pancreas, Peripheral nervous system, Phenoxybenzamine, Phentolamine, Phosphorylase kinase, Piribedil, Platelet, Prefrontal cortex, Protein kinase A, Quetiapine, Rauwolscine, Receptor antagonist, Rilmenidine, Risperidone, Romifidine, Rotigotine, Salivary gland, SB-269970, Sedation, Septum, Setiptiline, Smooth muscle tissue, Solitary nucleus, Spasms, Sphincter, Spinal cord, Spiroxatrine, Stimulant, Sympathetic nervous system, Synapse, Talipexole, TDIQ, Tetracyclic antidepressant, Tiamenidine, Tic, Tizanidine, Tolazoline, Tolonidine, Transdermal, UGT1A4, United States National Library of Medicine, Vascular smooth muscle, Vasoconstriction, Vein, Veterinary medicine, WebMD, Xylazine, Xylometazoline, Yohimbine, Ziprasidone, Zotepine, (R)-3-Nitrobiphenyline, 4-NEMD, 5-HT1A receptor, 5-HT3 receptor. Expand index (102 more) »
Acetylcholine
Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.
New!!: Alpha-2 adrenergic receptor and Acetylcholine · See more »
Adderall
Adderall, Adderall XR, and Mydayis are combination drugs containing four salts of the two enantiomers of amphetamine, a central nervous system (CNS) stimulant of the phenethylamine class.
New!!: Alpha-2 adrenergic receptor and Adderall · See more »
Adenylyl cyclase
Adenylyl cyclase (also commonly known as adenyl cyclase and adenylate cyclase, abbreviated AC) is an enzyme with key regulatory roles in essentially all cells.
New!!: Alpha-2 adrenergic receptor and Adenylyl cyclase · See more »
Adipose tissue
In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes.
New!!: Alpha-2 adrenergic receptor and Adipose tissue · See more »
Adrenal medulla
The adrenal medulla (medulla glandulae suprarenalis) is part of the adrenal gland.
New!!: Alpha-2 adrenergic receptor and Adrenal medulla · See more »
Adrenaline
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
New!!: Alpha-2 adrenergic receptor and Adrenaline · See more »
Adrenergic receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline).
New!!: Alpha-2 adrenergic receptor and Adrenergic receptor · See more »
Agmatine
Agmatine, also known as (4-aminobutyl)guanidine, is an aminoguanidine that was discovered in 1910 by Albrecht Kossel.
New!!: Alpha-2 adrenergic receptor and Agmatine · See more »
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
New!!: Alpha-2 adrenergic receptor and Agonist · See more »
Allosteric regulation
In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site.
New!!: Alpha-2 adrenergic receptor and Allosteric regulation · See more »
Alpha blocker
Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors).
New!!: Alpha-2 adrenergic receptor and Alpha blocker · See more »
Alpha-1 adrenergic receptor
The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein.
New!!: Alpha-2 adrenergic receptor and Alpha-1 adrenergic receptor · See more »
Alpha-1A adrenergic receptor
The alpha-1A adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.
New!!: Alpha-2 adrenergic receptor and Alpha-1A adrenergic receptor · See more »
Alpha-1B adrenergic receptor
The alpha-1B adrenergic receptor (α1B adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.
New!!: Alpha-2 adrenergic receptor and Alpha-1B adrenergic receptor · See more »
Alpha-1D adrenergic receptor
The alpha-1D adrenergic receptor (α1D adrenoreceptor), also known as ADRA1D, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.
New!!: Alpha-2 adrenergic receptor and Alpha-1D adrenergic receptor · See more »
Alpha-2A adrenergic receptor
The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2 adrenergic receptor, and also denotes the human gene encoding it.
New!!: Alpha-2 adrenergic receptor and Alpha-2A adrenergic receptor · See more »
Alpha-2B adrenergic receptor
The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor.
New!!: Alpha-2 adrenergic receptor and Alpha-2B adrenergic receptor · See more »
Alpha-2C adrenergic receptor
The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it.
New!!: Alpha-2 adrenergic receptor and Alpha-2C adrenergic receptor · See more »
Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
New!!: Alpha-2 adrenergic receptor and Analgesic · See more »
Anesthesia
In the practice of medicine (especially surgery and dentistry), anesthesia or anaesthesia (from Greek "without sensation") is a state of temporary induced loss of sensation or awareness.
New!!: Alpha-2 adrenergic receptor and Anesthesia · See more »
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure).
New!!: Alpha-2 adrenergic receptor and Antihypertensive drug · See more »
Apraclonidine
Apraclonidine (INN), also known under the brand name Iopidine, is a sympathomimetic used in glaucoma therapy.
New!!: Alpha-2 adrenergic receptor and Apraclonidine · See more »
Aripiprazole
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. It is recommended and primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders, and irritability associated with autism. According to a Cochrane review, evidence for the oral form in schizophrenia is not sufficient to determine effects on general functioning. Additionally, because many people dropped out of the medication trials before they were completed, the overall strength of the conclusions is low. Side effects include neuroleptic malignant syndrome, a movement disorder known as tardive dyskinesia, and high blood sugar in those with diabetes. In the elderly there is an increased risk of death. It is thus not recommended for use in those with psychosis due to dementia. It is pregnancy category C in the United States and category C in Australia, meaning there is possible evidence of harm to the fetus. It is not recommended for women who are breastfeeding. It is unclear whether it is safe or effective in people less than 18 years old. It is a partial dopamine agonist. Aripiprazole was developed by Otsuka in Japan. In the United States, Otsuka America markets it jointly with Bristol-Myers Squibb. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.
New!!: Alpha-2 adrenergic receptor and Aripiprazole · See more »
Artery
An artery (plural arteries) is a blood vessel that takes blood away from the heart to all parts of the body (tissues, lungs, etc).
New!!: Alpha-2 adrenergic receptor and Artery · See more »
Asenapine
Asenapine, sold under the trade names Saphris and Sycrest among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder.
New!!: Alpha-2 adrenergic receptor and Asenapine · See more »
Atipamezole
Atipamezole (brand name Antisedan) is a synthetic α2 adrenergic receptor antagonist indicated for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.
New!!: Alpha-2 adrenergic receptor and Atipamezole · See more »
Attention deficit hyperactivity disorder
Attention-deficit hyperactivity disorder (ADHD) is a mental disorder of the neurodevelopmental type.
New!!: Alpha-2 adrenergic receptor and Attention deficit hyperactivity disorder · See more »
Autoreceptor
An autoreceptor is a type of receptor located in the membranes of presynaptic nerve cells.
New!!: Alpha-2 adrenergic receptor and Autoreceptor · See more »
Beta-2 adrenergic receptor
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via a downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation.
New!!: Alpha-2 adrenergic receptor and Beta-2 adrenergic receptor · See more »
Brainstem
The brainstem (or brain stem) is the posterior part of the brain, adjoining and structurally continuous with the spinal cord.
New!!: Alpha-2 adrenergic receptor and Brainstem · See more »
Brimonidine
Brimonidine is a drug used as eye drops under the brand names Alphagan and Alphagan-P to treat open-angle glaucoma or ocular hypertension, and as a gel, Mirvaso, for facial skin redness in rosacea.
New!!: Alpha-2 adrenergic receptor and Brimonidine · See more »
BRL-44408
BRL-44408 is a drug used in scientific research which acts as a selective antagonist for the α2A adrenoreceptor.
New!!: Alpha-2 adrenergic receptor and BRL-44408 · See more »
Cannabigerol
Cannabigerol is one of some 560 cannabinoid compounds found in the plant genus Cannabis.
New!!: Alpha-2 adrenergic receptor and Cannabigerol · See more »
Cannabinoid receptor type 1
The cannabinoid type 1 receptor, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located in the central and peripheral nervous system.
New!!: Alpha-2 adrenergic receptor and Cannabinoid receptor type 1 · See more »
Catecholamine
A catecholamine (CA) is a monoamine, an organic compound that has a catechol (benzene with two hydroxyl side groups at carbons 1 and 2) and a side-chain amine.
New!!: Alpha-2 adrenergic receptor and Catecholamine · See more »
Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
New!!: Alpha-2 adrenergic receptor and Central nervous system · See more »
Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates.
New!!: Alpha-2 adrenergic receptor and Cerebellum · See more »
Cerebral cortex
The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.
New!!: Alpha-2 adrenergic receptor and Cerebral cortex · See more »
Chemical synapse
Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.
New!!: Alpha-2 adrenergic receptor and Chemical synapse · See more »
Cirazoline
Cirazoline is a full agonist at the α1A adrenergic receptor, a partial agonist at both the α1B and α1D adrenergic receptors, and a nonselective antagonist to the α2 adrenergic receptor.
New!!: Alpha-2 adrenergic receptor and Cirazoline · See more »
Clonidine
Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions.
New!!: Alpha-2 adrenergic receptor and Clonidine · See more »
Clozapine
Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication.
New!!: Alpha-2 adrenergic receptor and Clozapine · See more »
Coronary arteries
The coronary arteries are the arteries of the coronary circulation that transport blood into and out of the cardiac muscle.
New!!: Alpha-2 adrenergic receptor and Coronary arteries · See more »
Cramp
A cramp is a sudden, involuntary muscle contraction or over-shortening; while generally temporary and non-damaging, they can cause significant pain, and a paralysis-like immobility of the affected muscle.
New!!: Alpha-2 adrenergic receptor and Cramp · See more »
Cyclic adenosine monophosphate
Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes.
New!!: Alpha-2 adrenergic receptor and Cyclic adenosine monophosphate · See more »
CYP1A2
Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.
New!!: Alpha-2 adrenergic receptor and CYP1A2 · See more »
CYP2D6
Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.
New!!: Alpha-2 adrenergic receptor and CYP2D6 · See more »
CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
New!!: Alpha-2 adrenergic receptor and CYP3A4 · See more »
Department of Health (Australia)
The Department of Health is a department of the Government of Australia charged with overseeing the running of Australia's health system, including supporting universal and affordable access to medical, pharmaceutical and hospital services, as well as helping people to stay healthy through health promotion, participation and exercise and other disease prevention activities.
New!!: Alpha-2 adrenergic receptor and Department of Health (Australia) · See more »
Detomidine
Detomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses.
New!!: Alpha-2 adrenergic receptor and Detomidine · See more »
Dexmedetomidine
Dexmedetomidine, sold under the trade name Precedex among others, is an anxiety reducing, sedative, and pain medication.
New!!: Alpha-2 adrenergic receptor and Dexmedetomidine · See more »
Efaroxan
Efaroxan is an α2-adrenergic receptor antagonist and antagonist of the imidazoline receptor.
New!!: Alpha-2 adrenergic receptor and Efaroxan · See more »
Epidural administration
Epidural administration (from Ancient Greek ἐπί, "on, upon" + dura mater) is a medical route of administration in which a drug such as epidural analgesia and epidural anaesthesia or contrast agent is injected into the epidural space around the spinal cord.
New!!: Alpha-2 adrenergic receptor and Epidural administration · See more »
European Medicines Agency
The European Medicines Agency (EMA) is a European Union agency for the evaluation of medicinal products.
New!!: Alpha-2 adrenergic receptor and European Medicines Agency · See more »
G protein
G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.
New!!: Alpha-2 adrenergic receptor and G protein · See more »
G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
New!!: Alpha-2 adrenergic receptor and G protein–coupled receptor · See more »
Gastrointestinal tract
The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.
New!!: Alpha-2 adrenergic receptor and Gastrointestinal tract · See more »
Gi alpha subunit
Gi alpha subunit (Gαi, or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP.
New!!: Alpha-2 adrenergic receptor and Gi alpha subunit · See more »
Glucagon
Glucagon is a peptide hormone, produced by alpha cells of the pancreas.
New!!: Alpha-2 adrenergic receptor and Glucagon · See more »
Glycogen phosphorylase
Glycogen phosphorylase is one of the phosphorylase enzymes.
New!!: Alpha-2 adrenergic receptor and Glycogen phosphorylase · See more »
Guanabenz
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug.
New!!: Alpha-2 adrenergic receptor and Guanabenz · See more »
Guanfacine
Guanfacine (trade names Estulic, Tenex, and, in extended release form, Intuniv) is a sympatholytic drug used to treat hypertension and attention deficit hyperactivity disorder (ADHD).
New!!: Alpha-2 adrenergic receptor and Guanfacine · See more »
Heart
The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.
New!!: Alpha-2 adrenergic receptor and Heart · See more »
Heterotrimeric G protein
"G protein" usually refers to the membrane-associated heterotrimeric G proteins, sometimes referred to as the "large" G proteins (as opposed to the subclass of smaller, monomeric small GTPases).
New!!: Alpha-2 adrenergic receptor and Heterotrimeric G protein · See more »
Hippocampus
The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.
New!!: Alpha-2 adrenergic receptor and Hippocampus · See more »
Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
New!!: Alpha-2 adrenergic receptor and Hypertension · See more »
Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
New!!: Alpha-2 adrenergic receptor and Hypotension · See more »
Hypothalamus
The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.
New!!: Alpha-2 adrenergic receptor and Hypothalamus · See more »
Idazoxan
Idazoxan (INN) is a drug which is used in scientific research.
New!!: Alpha-2 adrenergic receptor and Idazoxan · See more »
Imidazoline receptor
Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act.
New!!: Alpha-2 adrenergic receptor and Imidazoline receptor · See more »
Imiloxan
Imiloxan is a drug which is used in scientific research.
New!!: Alpha-2 adrenergic receptor and Imiloxan · See more »
Insulin
Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.
New!!: Alpha-2 adrenergic receptor and Insulin · See more »
Intensive care unit
Intensive care unit An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive treatment medicine.
New!!: Alpha-2 adrenergic receptor and Intensive care unit · See more »
Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
New!!: Alpha-2 adrenergic receptor and Intravenous therapy · See more »
Lipolysis
Lipolysis is the breakdown of lipids and involves hydrolysis of triglycerides into glycerol and free fatty acids.
New!!: Alpha-2 adrenergic receptor and Lipolysis · See more »
Locus coeruleus
The locus coeruleus (\-si-ˈrü-lē-əs\, also spelled locus caeruleus or locus ceruleus) is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic.
New!!: Alpha-2 adrenergic receptor and Locus coeruleus · See more »
Lofexidine
Lofexidine, sold under the brand name Lucemyra among others, is a medication historically used to treat high blood pressure, but more commonly used to help with the physical symptoms of opioid withdrawal.
New!!: Alpha-2 adrenergic receptor and Lofexidine · See more »
Lurasidone
Lurasidone (trade name Latuda) is an atypical antipsychotic developed by Dainippon Sumitomo Pharma and marketed by Sunovion in the U.S. It has been an FDA approved treatment for schizophrenia since 2010 and for treating depressive episodes in adults with bipolar I disorder since 2013.
New!!: Alpha-2 adrenergic receptor and Lurasidone · See more »
Medetomidine
Medetomidine is a synthetic drug used as both a surgical anesthetic and analgesic.
New!!: Alpha-2 adrenergic receptor and Medetomidine · See more »
Medulla oblongata
The medulla oblongata (or medulla) is located in the brainstem, anterior and partially inferior to the cerebellum.
New!!: Alpha-2 adrenergic receptor and Medulla oblongata · See more »
Melperone
Melperone (Bunil (PT), Buronil (AT, BE, CZ, DK, FL†, NL†, NO†, SE), Eunerpan (DE)) is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol.
New!!: Alpha-2 adrenergic receptor and Melperone · See more »
Methamphetamine
Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.
New!!: Alpha-2 adrenergic receptor and Methamphetamine · See more »
Methylphenidate
Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
New!!: Alpha-2 adrenergic receptor and Methylphenidate · See more »
Mianserin
Mianserin, sold under the brand name Tolvon among others, is an atypical antidepressant which is used in the treatment of depression in Europe and elsewhere in the world.
New!!: Alpha-2 adrenergic receptor and Mianserin · See more »
Midbrain
The midbrain or mesencephalon (from Greek mesos 'middle', and enkephalos 'brain') is a portion of the central nervous system associated with vision, hearing, motor control, sleep/wake, arousal (alertness), and temperature regulation.
New!!: Alpha-2 adrenergic receptor and Midbrain · See more »
Mirtazapine
Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant which is used primarily in the treatment of depression.
New!!: Alpha-2 adrenergic receptor and Mirtazapine · See more »
Mivazerol
Mivazerol is an alpha-adrenergic agonist.
New!!: Alpha-2 adrenergic receptor and Mivazerol · See more »
Neurotransmission
Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through"), also called synaptic transmission, is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and activate the receptors on the dendrites of another neuron (the postsynaptic neuron).
New!!: Alpha-2 adrenergic receptor and Neurotransmission · See more »
Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
New!!: Alpha-2 adrenergic receptor and Neurotransmitter · See more »
Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are receptor proteins that respond to the neurotransmitter acetylcholine.
New!!: Alpha-2 adrenergic receptor and Nicotinic acetylcholine receptor · See more »
Nitric oxide synthase
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.
New!!: Alpha-2 adrenergic receptor and Nitric oxide synthase · See more »
NMDA receptor antagonist
NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).
New!!: Alpha-2 adrenergic receptor and NMDA receptor antagonist · See more »
Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
New!!: Alpha-2 adrenergic receptor and Norepinephrine · See more »
Olanzapine
Olanzapine (originally branded Zyprexa) is an antipsychotic medication used to treat schizophrenia and bipolar disorder.
New!!: Alpha-2 adrenergic receptor and Olanzapine · See more »
Opioid use disorder
Opioid use disorder is a medical condition characterized by a problematic pattern of opioid use that causes clinically significant impairment or distress.
New!!: Alpha-2 adrenergic receptor and Opioid use disorder · See more »
Oxymetazoline
Oxymetazoline is a selective α1 adrenergic receptor agonist and α2 adrenergic receptor partial agonist.
New!!: Alpha-2 adrenergic receptor and Oxymetazoline · See more »
Paliperidone
Paliperidone, sold under the trade name Invega among others, is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications.
New!!: Alpha-2 adrenergic receptor and Paliperidone · See more »
Pancreas
The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.
New!!: Alpha-2 adrenergic receptor and Pancreas · See more »
Peripheral nervous system
The peripheral nervous system (PNS) is one of the two components of the nervous system, the other part is the central nervous system (CNS).
New!!: Alpha-2 adrenergic receptor and Peripheral nervous system · See more »
Phenoxybenzamine
Phenoxybenzamine (marketed under the trade name Dibenzyline) is a non-selective, irreversible alpha blocker.
New!!: Alpha-2 adrenergic receptor and Phenoxybenzamine · See more »
Phentolamine
Phentolamine (Regitine) is a reversible nonselective α-adrenergic antagonist.
New!!: Alpha-2 adrenergic receptor and Phentolamine · See more »
Phosphorylase kinase
Phosphorylase kinase (PhK) is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release glucose-1-phosphate from glycogen.
New!!: Alpha-2 adrenergic receptor and Phosphorylase kinase · See more »
Piribedil
Piribedil (trade names Pronoran, Trivastal Retard, Trastal, Trivastan, Clarium and others) is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist.
New!!: Alpha-2 adrenergic receptor and Piribedil · See more »
Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
New!!: Alpha-2 adrenergic receptor and Platelet · See more »
Prefrontal cortex
In mammalian brain anatomy, the prefrontal cortex (PFC) is the cerebral cortex which covers the front part of the frontal lobe.
New!!: Alpha-2 adrenergic receptor and Prefrontal cortex · See more »
Protein kinase A
In cell biology, protein kinase A (PKANot to be confused with pKa, the symbol for the acid dissociation constant.) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP).
New!!: Alpha-2 adrenergic receptor and Protein kinase A · See more »
Quetiapine
Quetiapine, marketed as Seroquel among other names, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
New!!: Alpha-2 adrenergic receptor and Quetiapine · See more »
Rauwolscine
Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauwolfia and Pausinystalia (formerly known as Corynanthe).
New!!: Alpha-2 adrenergic receptor and Rauwolscine · See more »
Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
New!!: Alpha-2 adrenergic receptor and Receptor antagonist · See more »
Rilmenidine
Rilmenidine is a prescription medication for the treatment of hypertension.
New!!: Alpha-2 adrenergic receptor and Rilmenidine · See more »
Risperidone
Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication.
New!!: Alpha-2 adrenergic receptor and Risperidone · See more »
Romifidine
Romifidine is a drug that is used in veterinary medicine as a sedative mainly in large animals such as horses, although it may be used in a wide variety of species.
New!!: Alpha-2 adrenergic receptor and Romifidine · See more »
Rotigotine
Rotigotine (Neupro) is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS).
New!!: Alpha-2 adrenergic receptor and Rotigotine · See more »
Salivary gland
The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts.
New!!: Alpha-2 adrenergic receptor and Salivary gland · See more »
SB-269970
SB-269970 is a drug and research chemical developed by GlaxoSmithKline used in scientific studies.
New!!: Alpha-2 adrenergic receptor and SB-269970 · See more »
Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.
New!!: Alpha-2 adrenergic receptor and Sedation · See more »
Septum
In biology, a septum (Latin for something that encloses; plural septa) is a wall, dividing a cavity or structure into smaller ones.
New!!: Alpha-2 adrenergic receptor and Septum · See more »
Setiptiline
Setiptiline (brand name Tecipul), also known as teciptiline, is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
New!!: Alpha-2 adrenergic receptor and Setiptiline · See more »
Smooth muscle tissue
Smooth muscle is an involuntary non-striated muscle.
New!!: Alpha-2 adrenergic receptor and Smooth muscle tissue · See more »
Solitary nucleus
In the human brainstem, the solitary nucleus (SN) (nucleus of the solitary tract, nucleus solitarius, nucleus tractus solitarii) is a series of purely sensory nuclei (clusters of nerve cell bodies) forming a vertical column of grey matter embedded in the medulla oblongata.
New!!: Alpha-2 adrenergic receptor and Solitary nucleus · See more »
Spasms
Spasms is a 1983 Canadian horror film directed by William Fruet and starring Peter Fonda, Oliver Reed, and Kerrie Keane.
New!!: Alpha-2 adrenergic receptor and Spasms · See more »
Sphincter
A sphincter is a circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.
New!!: Alpha-2 adrenergic receptor and Sphincter · See more »
Spinal cord
The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.
New!!: Alpha-2 adrenergic receptor and Spinal cord · See more »
Spiroxatrine
Spiroxatrine is a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor.
New!!: Alpha-2 adrenergic receptor and Spiroxatrine · See more »
Stimulant
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.
New!!: Alpha-2 adrenergic receptor and Stimulant · See more »
Sympathetic nervous system
The sympathetic nervous system (SNS) is one of the two main divisions of the autonomic nervous system, the other being the parasympathetic nervous system.
New!!: Alpha-2 adrenergic receptor and Sympathetic nervous system · See more »
Synapse
In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target efferent cell.
New!!: Alpha-2 adrenergic receptor and Synapse · See more »
Talipexole
Talipexole (B-HT920, Domnin) is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996.
New!!: Alpha-2 adrenergic receptor and Talipexole · See more »
TDIQ
TDIQ (also known as 6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline or MDTHIQ) is a drug used in scientific research, which has anxiolytic and anorectic effects in animals.
New!!: Alpha-2 adrenergic receptor and TDIQ · See more »
Tetracyclic antidepressant
Tetracyclic antidepressants (TeCAs) are a class of antidepressants that were first introduced starting in the 1970s.
New!!: Alpha-2 adrenergic receptor and Tetracyclic antidepressant · See more »
Tiamenidine
Tiamenidine (BAN, USAN, INN, also known as thiamenidine, Hoe 440) is a imidazoline compound that shares many of the pharmacological properties of clonidine.
New!!: Alpha-2 adrenergic receptor and Tiamenidine · See more »
Tic
A tic is a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups.
New!!: Alpha-2 adrenergic receptor and Tic · See more »
Tizanidine
Tizanidine (trade names Zanaflex (Acorda Therapeutics), Sirdalud (Novartis), Relentus (Beximco Pharma) Is a centrally acting α2 adrenergic agonist used as a muscle relaxant. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia. Tizanidine has been found to be as effective as other antispasmodic drugs and is more tolerable than baclofen and diazepam. Tizanidine can be very strong even at the 2 mg dose and may cause hypotension, so caution is advised when it is used in patients who have a history of orthostatic hypotension, or when switching from gel cap to tablet form and vice versa. Tizanidine can occasionally cause acute liver failure. Clinical trials show that up to 5% of patients treated with tizanidine had elevated liver function test values, though symptoms disappeared upon withdrawal of the drug. Care should be used when first beginning treatment with tizanidine with regular liver tests for the first six months of treatment. As of 2015 the cost for a typical month of medication in the United States is US$100200.
New!!: Alpha-2 adrenergic receptor and Tizanidine · See more »
Tolazoline
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
New!!: Alpha-2 adrenergic receptor and Tolazoline · See more »
Tolonidine
Tolonidine is an antihypertensive.
New!!: Alpha-2 adrenergic receptor and Tolonidine · See more »
Transdermal
Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.
New!!: Alpha-2 adrenergic receptor and Transdermal · See more »
UGT1A4
UDP-glucuronosyltransferase 1-4 is an enzyme that in humans is encoded by the UGT1A4 gene.
New!!: Alpha-2 adrenergic receptor and UGT1A4 · See more »
United States National Library of Medicine
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.
New!!: Alpha-2 adrenergic receptor and United States National Library of Medicine · See more »
Vascular smooth muscle
Vascular smooth muscle refers to the particular type of smooth muscle found within, and composing the majority of the wall of blood vessels.
New!!: Alpha-2 adrenergic receptor and Vascular smooth muscle · See more »
Vasoconstriction
Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.
New!!: Alpha-2 adrenergic receptor and Vasoconstriction · See more »
Vein
Veins are blood vessels that carry blood toward the heart.
New!!: Alpha-2 adrenergic receptor and Vein · See more »
Veterinary medicine
Veterinary medicine is the branch of medicine that deals with the prevention, diagnosis and treatment of disease, disorder and injury in non-human animals.
New!!: Alpha-2 adrenergic receptor and Veterinary medicine · See more »
WebMD
WebMD is an American corporation known primarily as an online publisher of news and information pertaining to human health and well-being.
New!!: Alpha-2 adrenergic receptor and WebMD · See more »
Xylazine
Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor.
New!!: Alpha-2 adrenergic receptor and Xylazine · See more »
Xylometazoline
Xylometazoline, also spelled xylomethazoline, is a medication which is used to improve symptoms of nasal congestion, allergic rhinitis, and sinusitis.
New!!: Alpha-2 adrenergic receptor and Xylometazoline · See more »
Yohimbine
Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree in Central Africa.
New!!: Alpha-2 adrenergic receptor and Yohimbine · See more »
Ziprasidone
Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic which is used for the treatment of schizophrenia as well as acute mania and mixed states associated with bipolar disorder.
New!!: Alpha-2 adrenergic receptor and Ziprasidone · See more »
Zotepine
Zotepine (brand names: Losizopilon (JP), Lodopin (ID, JP), Setous (JP), Zoleptil (CZ, PT, TR, UK†); where † indicates a formulation that has been discontinued) is an atypical antipsychotic drug indicated for acute and chronic schizophrenia.
New!!: Alpha-2 adrenergic receptor and Zotepine · See more »
(R)-3-Nitrobiphenyline
(R)-3-Nitrobiphenyline is a drug which acts as an α2-adrenergic agonist, selective for the α2C subtype, as well as being a weak antagonist at the α2A and α2B subtypes.
New!!: Alpha-2 adrenergic receptor and (R)-3-Nitrobiphenyline · See more »
4-NEMD
4-NEMD is a potent sedative drug which acts as a selective alpha-2 adrenergic agonist.
New!!: Alpha-2 adrenergic receptor and 4-NEMD · See more »
5-HT1A receptor
The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
New!!: Alpha-2 adrenergic receptor and 5-HT1A receptor · See more »
5-HT3 receptor
The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin) receptors which are G protein-coupled receptors.
New!!: Alpha-2 adrenergic receptor and 5-HT3 receptor · See more »
Redirects here:
A-2 adrenergic receptor, A-2 agonist, A2 adrenergic receptor, A2 agonist, A2 receptor, A2-adrenergic, A2-adrenergic receptor, A2-receptor agonist, Alpha 2 receptor, Alpha-2 adrenergic, Alpha-2 adrenergic receptors, Alpha-2 adrenoceptor, Alpha-2 adrenoceptors, Alpha-2 adrenoreceptor, Alpha-2 receptor, Alpha2-adrenergic agonist, Alpha2-adrenergic agonists, Alpha2-adrenergic receptor, Alpha2-agonist, Α-2 adrenergic receptor, Α-2 agonist, Α2 adrenergic receptor, Α2 adrenoceptor, Α2 agonist, Α2 receptor, Α2-Adrenergic receptor, Α2-adrenergic, Α2-adrenergic receptor, Α2-receptor agonist.
References
[1] https://en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor
