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Anthrax vaccines

Index Anthrax vaccines

Vaccines against the livestock and human disease anthrax—caused by the bacterium Bacillus anthracis—have had a prominent place in the history of medicine, from Pasteur’s pioneering 19th-century work with cattle (the first effective bacterial vaccine and the second effective vaccine ever) to the controversial late 20th century use of a modern product to protect American troops against the use of anthrax in biological warfare. [1]

78 relations: Adjuvant, Afghanistan, Alum, Aluminium hydroxide, Annals of Saudi Medicine, Anthrax, Anthrax toxin, Anthrax vaccine adsorbed, Anthrax Vaccine Immunization Program, Antitoxin, Bacillus anthracis, Bacteria, Bibliothèque nationale de France, Biological warfare, Bioterrorism, Cattle, Columbia University Press, Cowpox, Cutaneous condition, Edward Jenner, Emergent BioSolutions, Erythema, Fever, Food and Drug Administration, Fowl cholera, George Eliava Institute, Gerald L. Geison, Government Accountability Office, Gulf War, Harry Smith (microbiologist), Iraq, Israel, Israel Defense Forces, Israel Institute for Biological Research, Jean Joseph Henri Toussaint, Jeanne Guillemin, Lansing, Michigan, Lecithin, Louis Pasteur, Max Perutz, Ministry of Defense (Israel), National Institutes of Health, Op. cit., Pain, Patent, Pertussis vaccine, Polysorbate 80, Porton Down, Potassium alum, Potassium dichromate, ..., Pretoria, Rabies, Reactogenicity, Recombinant DNA, Rhesus macaque, RT (TV network), Saponin, Smallpox, Sodium chloride, South Korea, Soviet Union, Squalene, Strategic National Stockpile, Tbilisi, The Independent, The New York Review of Books, The New York Times, Thiomersal, Toulouse, Treatment and control groups, United States, United States Department of Defense, United States Department of Health and Human Services, Vaccination, Vaccine, Vaccine (journal), Variolation, Veterinary surgery. Expand index (28 more) »

Adjuvant

An adjuvant is a pharmacological or immunological agent that modifies the effect of other agents.

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Afghanistan

Afghanistan (Pashto/Dari:, Pashto: Afġānistān, Dari: Afġānestān), officially the Islamic Republic of Afghanistan, is a landlocked country located within South Asia and Central Asia.

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Alum

An alum is a type of chemical compound, usually a hydrated double sulfate salt of aluminium with the general formula, where X is a monovalent cation such as potassium or ammonium.

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Aluminium hydroxide

Aluminium hydroxide, Al(OH)3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarer polymorphs: bayerite, doyleite, and nordstrandite.

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Annals of Saudi Medicine

The Annals of Saudi Medicine is a bimonthly peer-reviewed medical journal published by the King Faisal Specialist Hospital and Research Centre (Riyadh, Saudi Arabia).

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Anthrax

Anthrax is an infection caused by the bacterium Bacillus anthracis.

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Anthrax toxin

Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium, Bacillus anthracis—the causative agent of anthrax.

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Anthrax vaccine adsorbed

Anthrax vaccine adsorbed (AVA) is the only FDA-licensed human anthrax vaccine in the United States.

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Anthrax Vaccine Immunization Program

The Anthrax Vaccine Immunization Program (AVIP), is the name of the policy set forth by the U.S. federal government to immunize its military and certain civilian personnel with the BioThrax anthrax vaccine.

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Antitoxin

An antitoxin is an antibody with the ability to neutralize a specific toxin.

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Bacillus anthracis

Bacillus anthracis is the etiologic agent of anthrax—a common disease of livestock and, occasionally, of humans—and the only obligate pathogen within the genus Bacillus.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Bibliothèque nationale de France

The (BnF, English: National Library of France) is the national library of France, located in Paris.

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Biological warfare

Biological warfare (BW)—also known as germ warfare—is the use of biological toxins or infectious agents such as bacteria, viruses, and fungi with the intent to kill or incapacitate humans, animals or plants as an act of war.

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Bioterrorism

Bioterrorism is terrorism involving the intentional release or dissemination of biological agents.

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Cattle

Cattle—colloquially cows—are the most common type of large domesticated ungulates.

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Columbia University Press

Columbia University Press is a university press based in New York City, and affiliated with Columbia University.

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Cowpox

Cowpox is an infectious disease caused by the cowpox virus.

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Cutaneous condition

A cutaneous condition is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.

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Edward Jenner

Edward Jenner, FRS FRCPE (17 May 1749 – 26 January 1823) was an English physician and scientist who was the pioneer of smallpox vaccine, the world's first vaccine.

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Emergent BioSolutions

Emergent BioSolutions is a multinational specialty biopharmaceutical company headquartered in Gaithersburg, Maryland, USA.

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Erythema

Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.

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Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Fowl cholera

Fowl cholera is also called avian cholera, avian pasteurellosis, avian hemorrhagic septicemia. It is the most common pasteurellosis of poultry.

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George Eliava Institute

The George Eliava Institute of Bacteriophage, Microbiology and Virology (aka Tbilisi Institute) has been active since the 1930s in the field of phage therapy, which is used to combat microbial infection (cf. antibiotic-resistant strains).

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Gerald L. Geison

Gerald Lynn Geison, historian, born 1943 in Savanna, Illinois, died at 58 in 2001.

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Government Accountability Office

The Government Accountability Office (GAO) is a legislative branch government agency that provides auditing, evaluation, and investigative services for the United States Congress.

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Gulf War

The Gulf War (2 August 199028 February 1991), codenamed Operation Desert Shield (2 August 199017 January 1991) for operations leading to the buildup of troops and defense of Saudi Arabia and Operation Desert Storm (17 January 199128 February 1991) in its combat phase, was a war waged by coalition forces from 35 nations led by the United States against Iraq in response to Iraq's invasion and annexation of Kuwait.

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Harry Smith (microbiologist)

Harry Smith (7 August 1921 – 10 December 2011) was a British microbiologist, and Professor of Microbiology, at the University of Birmingham.

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Iraq

Iraq (or; العراق; عێراق), officially known as the Republic of Iraq (جُمُهورية العِراق; کۆماری عێراق), is a country in Western Asia, bordered by Turkey to the north, Iran to the east, Kuwait to the southeast, Saudi Arabia to the south, Jordan to the southwest and Syria to the west.

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Israel

Israel, officially the State of Israel, is a country in the Middle East, on the southeastern shore of the Mediterranean Sea and the northern shore of the Red Sea.

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Israel Defense Forces

The Israel Defense Forces (IDF; צְבָא הַהֲגָנָה לְיִשְׂרָאֵל, lit. "The Army of Defense for Israel"; جيش الدفاع الإسرائيلي), commonly known in Israel by the Hebrew acronym Tzahal, are the military forces of the State of Israel.

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Israel Institute for Biological Research

Israel Institute for Biological Research (IIBR) is an Israeli government defense research institute specializing in biology, medicinal chemistry and environmental science.

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Jean Joseph Henri Toussaint

Jean Joseph Henri Toussaint (30 April 1847 – 3 August 1890) was a French veterinarian born in Rouvres-la-Chétive, department of Vosges.

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Jeanne Guillemin

Jeanne Harley Guillemin (born 1943) is a medical anthropologist and author, who for 25 years was a Professor of Sociology at Boston College and for the last ten years, a senior fellow in the at Massachusetts Institute of Technology.

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Lansing, Michigan

Lansing is the capital of the U.S. state of Michigan.

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Lecithin

Lecithin (from the Greek lekithos, "egg yolk") is a generic term to designate any group of yellow-brownish fatty substances occurring in animal and plant tissues, which are amphiphilic – they attract both water and fatty substances (and so are both hydrophilic and lipophilic), and are used for smoothing food textures, dissolving powders (emulsifying), homogenizing liquid mixtures, and repelling sticking materials.

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Louis Pasteur

Louis Pasteur (December 27, 1822 – September 28, 1895) was a French biologist, microbiologist and chemist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization.

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Max Perutz

Max Ferdinand Perutz (19 May 1914 – 6 February 2002) was an Austrian-born British molecular biologist, who shared the 1962 Nobel Prize for Chemistry with John Kendrew, for their studies of the structures of haemoglobin and myoglobin.

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Ministry of Defense (Israel)

The Ministry of Defense (מִשְׂרַד הַבִּטָּחוֹן, Misrad HaBitahon) of the government of Israel, is the governmental department responsible for defending the State of Israel from internal and external military threats.

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Op. cit.

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Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

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Patent

A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.

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Pertussis vaccine

Pertussis vaccine is a vaccine that protects against whooping cough (pertussis).

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Polysorbate 80

Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics.

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Porton Down

Porton Down is a United Kingdom science park, situated just northeast of the village of Porton near Salisbury, in Wiltshire, England.

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Potassium alum

Potassium alum, potash alum, or potassium aluminium sulfate is a chemical compound: the double sulfate of potassium and aluminium, with chemical formula KAl(SO4)2.

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Potassium dichromate

Potassium dichromate, K2Cr2O7, is a common inorganic chemical reagent, most commonly used as an oxidizing agent in various laboratory and industrial applications. As with all hexavalent chromium compounds, it is acutely and chronically harmful to health. It is a crystalline ionic solid with a very bright, red-orange color. The salt is popular in the laboratory because it is not deliquescent, in contrast to the more industrially relevant salt sodium dichromate.Gerd Anger, Jost Halstenberg, Klaus Hochgeschwender, Christoph Scherhag, Ulrich Korallus, Herbert Knopf, Peter Schmidt, Manfred Ohlinger, "Chromium Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005.

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Pretoria

Pretoria is a city in the northern part of Gauteng, South Africa.

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Rabies

Rabies is a viral disease that causes inflammation of the brain in humans and other mammals.

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Reactogenicity

In clinical trials, the term reactogenicity refers to the property of a vaccine of being able to produce common, “expected” adverse reactions, especially excessive immunological responses and associated signs and symptoms—fever, sore arm at injection site, etc.

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Recombinant DNA

Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in the genome.

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Rhesus macaque

The rhesus macaque (Macaca mulatta) is one of the best-known species of Old World monkeys.

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RT (TV network)

RT (formerly Russia Today) is a Russian international television network funded by the Russian government.

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Saponin

Saponins are a class of chemical compounds found in particular abundance in various plant species.

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Smallpox

Smallpox was an infectious disease caused by one of two virus variants, Variola major and Variola minor.

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Sodium chloride

Sodium chloride, also known as salt, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.

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South Korea

South Korea, officially the Republic of Korea (대한민국; Hanja: 大韓民國; Daehan Minguk,; lit. "The Great Country of the Han People"), is a country in East Asia, constituting the southern part of the Korean Peninsula and lying east to the Asian mainland.

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Soviet Union

The Soviet Union, officially the Union of Soviet Socialist Republics (USSR) was a socialist state in Eurasia that existed from 1922 to 1991.

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Squalene

Squalene is a natural 30-carbon organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name, as Squalus is a genus of sharks), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives.

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Strategic National Stockpile

The Strategic National Stockpile (SNS) is the United States' national repository of antibiotics, vaccines, chemical antidotes, antitoxins, and other critical medical equipment and supplies.

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Tbilisi

Tbilisi (თბილისი), in some countries also still named by its pre-1936 international designation Tiflis, is the capital and the largest city of Georgia, lying on the banks of the Kura River with a population of approximately 1.5 million people.

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The Independent

The Independent is a British online newspaper.

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The New York Review of Books

The New York Review of Books (or NYREV or NYRB) is a semi-monthly magazine with articles on literature, culture, economics, science and current affairs.

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The New York Times

The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.

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Thiomersal

Thiomersal (INN), or thimerosal (USAN, JAN), is an organomercury compound.

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Toulouse

Toulouse (Tolosa, Tolosa) is the capital of the French department of Haute-Garonne and of the region of Occitanie.

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Treatment and control groups

In the design of experiments, treatments are applied to experimental units in the treatment group(s).

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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United States Department of Defense

The Department of Defense (DoD, USDOD, or DOD) is an executive branch department of the federal government of the United States charged with coordinating and supervising all agencies and functions of the government concerned directly with national security and the United States Armed Forces.

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United States Department of Health and Human Services

The United States Department of Health and Human Services (HHS), also known as the Health Department, is a cabinet-level department of the U.S. federal government with the goal of protecting the health of all Americans and providing essential human services.

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Vaccination

Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen.

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Vaccine

A vaccine is a biological preparation that provides active acquired immunity to a particular disease.

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Vaccine (journal)

Vaccine is a peer-reviewed medical journal, published by Elsevier.

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Variolation

Variolation or inoculation was the method first used to immunize an individual against smallpox (Variola) with material taken from a patient or a recently variolated individual in the hope that a mild, but protective infection would result.

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Veterinary surgery

Veterinary surgery is surgery performed on animals by veterinarians, whereby the procedures fall into three broad categories: orthopaedics (bones, joints, muscles), soft tissue surgery (skin, body cavities, cardiovascular system, GI/urogenital/respiratory tracts), and neurosurgery. Advanced surgical procedures such as joint replacement (total hip, knee and elbow replacement), fracture repair, stabilization of cranial cruciate ligament deficiency, oncologic (cancer) surgery, herniated disc treatment, complicated gastrointestinal or urogenital procedures, kidney transplant, skin grafts, complicated wound management, minimally invasive procedures (arthroscopy, laparoscopy, thoracoscopy) are performed by veterinary surgeons (as registered in their jurisdiction). Most general practice veterinarians perform routine surgery, some also perform additional procedures. The goal of veterinary surgery may be quite different in pets and in farm animals. In the former, the situation is more close to that with human beings, where the benefit to the patient is the important factor. In the latter, the economic benefit is more important.

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Redirects here:

Anthrax Vaccine, Anthrax Vaccine Precipitated, Anthrax vaccine, Vaccine against anthrax.

References

[1] https://en.wikipedia.org/wiki/Anthrax_vaccines

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