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Cell adhesion

Index Cell adhesion

Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. [1]

80 relations: Adherens junction, Arthritis, Autoantibody, Autoimmune disease, Bacterial adhesin, Basal lamina, Biochemical cascade, Cadherin, Catenin, CD4, Cell adhesion molecule, Cell junction, Cell migration, Circumsporozoite protein, Claudin, Connexin, Connexon, Cytoskeleton, Desmocollin, Desmoglein, Desmosome, Differential adhesion hypothesis, Endothelium, Envelope glycoprotein GP120, Epithelium, Extracellular matrix, Fibronectin, Filamin, Flagellum, Focal adhesion, Fungus, Gap junction, Genetics, Hemagglutinin, Hemidesmosome, Hepatitis C virus, HIV, Immune system, Immunoglobulin domain, Immunoglobulin superfamily, Infection, Inflammation, Influenza, Integrin, Intercellular adhesion molecule, Intermediate filament, Keratin, Laminin, Leukocyte adhesion deficiency, Ligand, ..., Lymphocyte, Malaria, Merozoite surface protein, Metastasis, Microfilament, Multicellular organism, Neural cell adhesion molecule, Occludin, Paracellular transport, Pemphigus, Pilus, Plasmodesma, Plectin, Prokaryote, Protozoa, Red blood cell, Role of cell adhesions in neural development, Scaffold protein, Selectin, Sialic acid, Signal transduction, Sugar, Talin protein, Tight junction, Tropism, VCAM-1, Vinculin, Virus, Voltage-gated ion channel, White blood cell. Expand index (30 more) »

Adherens junction

Adherens junctions (or zonula adherens, intermediate junction, or "belt desmosome") are protein complexes that occur at cell–cell junctions in epithelial and endothelial tissues, usually more basal than tight junctions.

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Arthritis

Arthritis is a term often used to mean any disorder that affects joints.

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Autoantibody

An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins.

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Autoimmune disease

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

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Bacterial adhesin

Adhesins are cell-surface components or appendages of bacteria that facilitate adhesion or adherence to other cells or to surfaces, usually the host they are infecting or living in.

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Basal lamina

The basal lamina is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits.

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Biochemical cascade

A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus.

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Cadherin

Cadherins (named for "calcium-dependent adhesion") are a type of cell adhesion molecule (CAM) that is important in the formation of adherens junctions to bind cells with each other.

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Catenin

Catenins are a family of proteins found in complexes with cadherin cell adhesion molecules of animal cells.

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CD4

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.

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Cell adhesion molecule

Cell adhesion molecules (CAMs) are proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.

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Cell junction

A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals.

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Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms.

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Circumsporozoite protein

Circumsporozoite protein (CSP) is a secreted protein of the sporozoite stage of the malaria parasite (Plasmodium sp.) and is the antigenic target of RTS,S, a pre-erythrocytic malaria vaccine currently undergoing clinical trials.

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Claudin

Claudins are a family of proteins which, along with occludin, are the most important components of the tight junctions) (zonulae occludentes). Tight junctions establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.

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Connexin

Connexins (Cx), or gap junction proteins, are structurally related transmembrane proteins that assemble to form vertebrate gap junctions.

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Connexon

In biology, a connexon, also known as a connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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Desmocollin

Desmocollin is a type of cadherin.

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Desmoglein

The desmogleins are a family of cadherins consisting of proteins DSG1, DSG2, DSG3, and DSG4.

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Desmosome

A desmosome ("binding body"), also known as a macula adhaerens (plural: maculae adhaerentes) (Latin for adhering spot), is a cell structure specialized for cell-to-cell adhesion.

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Differential adhesion hypothesis

Differential adhesion hypothesis (DAH) is a hypothesis that explains cellular movement during morphogenesis with thermodynamic principles.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Envelope glycoprotein GP120

Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Extracellular matrix

In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.

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Fibronectin

Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.

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Filamin

Filamins are a class of proteins that hold two actin filaments at large angles.

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Flagellum

A flagellum (plural: flagella) is a lash-like appendage that protrudes from the cell body of certain bacterial and eukaryotic cells.

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Focal adhesion

In cell biology, focal adhesions (also cell–matrix adhesions or FAs) are large macromolecular assemblies through which mechanical force and regulatory signals are transmitted between the extracellular matrix (ECM) and an interacting cell.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Gap junction

A gap junction may also be called a nexus or macula communicans.

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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Hemagglutinin

Hemagglutinin or haemagglutinin (British English)p refers to a substance that causes red blood cells (RBCs) to agglutinate.

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Hemidesmosome

Hemidesmosomes (HD) are very small stud-like structures found in keratinocytes of the epidermis of skin that attach to the extracellular matrix (ECM).

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Hepatitis C virus

Hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae.

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HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunoglobulin domain

The immunoglobulin domain is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, consisting of about 125 amino acids.

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Immunoglobulin superfamily

The immunoglobulin superfamily (IgSF) is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells.

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Infection

Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Influenza

Influenza, commonly known as "the flu", is an infectious disease caused by an influenza virus.

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Integrin

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

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Intercellular adhesion molecule

In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily.

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Intermediate filament

Intermediate filaments (IFs) are cytoskeletal components found in the cells of vertebrate animal species, and perhaps also in other animals, fungi, plants, and unicellular organisms.

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Keratin

Keratin is one of a family of fibrous structural proteins.

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Laminin

Laminins are high-molecular weight (~400 to ~900 kDa) proteins of the extracellular matrix.

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Leukocyte adhesion deficiency

Leukocyte adhesion deficiency (LAD), is a rare autosomal recessive disorder characterized by immunodeficiency resulting in recurrent infections.

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Ligand

In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Malaria

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Merozoite surface protein

Merozoite surface proteins are both integral and peripheral membrane protein molecules found on the surface of a merozoite.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Microfilament

Microfilaments, also called actin filaments, are filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton.

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Multicellular organism

Multicellular organisms are organisms that consist of more than one cell, in contrast to unicellular organisms.

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Neural cell adhesion molecule

Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle.

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Occludin

Occludin is a protein that in humans is encoded by the OCLN gene.

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Paracellular transport

Paracellular transport refers to the transfer of substances across an epithelium by passing through the intercellular space between the cells.

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Pemphigus

Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes.

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Pilus

A pilus (Latin for 'hair'; plural: pili) is a hair-like appendage found on the surface of many bacteria.

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Plasmodesma

Plasmodesmata (singular: plasmodesma) are microscopic channels which traverse the cell walls of plant cells and some algal cells, enabling transport and communication between them.

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Plectin

Plectin is a giant protein found in nearly all mammalian cells which acts as a link between the three main components of the cytoskeleton: actin microfilaments, microtubules and intermediate filaments.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Protozoa

Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Role of cell adhesions in neural development

Cellular adhesions can be defined as proteins or protein aggregates that form mechanical and chemical linkages between the intracellular and extracellular space.

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Scaffold protein

In biology, scaffold proteins are crucial regulators of many key signalling pathways.

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Selectin

The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs).

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Sialic acid

Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone.

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Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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Sugar

Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food.

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Talin protein

Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell–substratum contact and, in lymphocytes, at cell–cell contacts.

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Tight junction

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens) are multiprotein junctional complex whose general function is to prevent leakage of transported solutes and water and seals the paracellular pathway.

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Tropism

A tropism (from Greek τρόπος, tropos, "a turning") is a biological phenomenon, indicating growth or turning movement of a biological organism, usually a plant, in response to an environmental stimulus.

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VCAM-1

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene.

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Vinculin

In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Redirects here:

Cell-cell adhesion, Cellular adhesion, Cell–cell adhesion, Tumor adhesion.

References

[1] https://en.wikipedia.org/wiki/Cell_adhesion

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