Cortactin and Lamellipodium

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Difference between Cortactin and Lamellipodium

Cortactin vs. Lamellipodium

Cortactin (from "cortical actin binding protein") is a monomeric protein located in the cytoplasm of cells that can be activated by external stimuli to promote polymerization and rearrangement of the actin cytoskeleton, especially the actin cortex around the cellular periphery. The lamellipodium (plural lamellipodia) (from Latin lamina, "thin sheet"; pod, "foot") is a cytoskeletal protein actin projection on the leading edge of the cell.

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Arp2/3 complex

Arp2/3 complex is a seven-subunit protein complex that plays a major role in the regulation of the actin cytoskeleton.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms.

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Chemotaxis

Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.

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Clathrin

Clathrin is a protein that plays a major role in the formation of coated vesicles.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Microfilament

Microfilaments, also called actin filaments, are filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton.

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Monomer

A monomer (mono-, "one" + -mer, "part") is a molecule that "can undergo polymerization thereby contributing constitutional units to the essential structure of a macromolecule".

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Nucleation

Nucleation is the first step in the formation of either a new thermodynamic phase or a new structure via self-assembly or self-organization.

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Treadmilling

Treadmilling is a phenomenon observed in many cellular cytoskeletal filaments, especially in actin filaments and microtubules.

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Tyrosine kinase

A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.

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WASL (gene)

Neural Wiskott-Aldrich syndrome protein is a protein that in humans is encoded by the WASL gene.

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Wiskott–Aldrich syndrome protein

The Wiskott–Aldrich Syndrome protein (WASp) is a 502-amino acid protein expressed in cells of the hematopoietic system.

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