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Dihydrotestosterone

Index Dihydrotestosterone

Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition. [1]

Table of Contents

  1. 209 relations: Acne, Adipose tissue, Adolf Butenandt, Adrenal gland, Adrenal steroid, Adverse effect, Agonist, Allopregnanolone, Allosteric modulator, Anabolic steroid, Anabolism, Androgen, Androgen backdoor pathway, Androgen receptor, Androgen-dependent condition, Androstane, Androstanedione, Androstanolone, Androstanolone propionate, Androstanolone valerate, Androstenedione, Androsterone, Antidepressant, Anxiety, Anxiolytic, Aromatase, Aromatization, Axilla, Benign prostatic hyperplasia, Binding selectivity, Bioassay, Bioconjugation, Biological activity, Biological half-life, Biosynthesis, Biotransformation, Birth defect, Body hair, Brain, Breast development, Buccal administration, Canada, Central nervous system, Chemical synthesis, Chest hair, Circulatory system, Clitoris, Congenital adrenal hyperplasia due to 21-hydroxylase deficiency, Correlation coefficient, Cryptorchidism, ... Expand index (159 more) »

  2. 5α-Reduced steroid metabolites
  3. Cyclopentanols
  4. Hormones of the hypothalamus-pituitary-gonad axis
  5. Hormones of the testis
  6. Human hormones
  7. Selective ERβ agonists
  8. Sex hormones
  9. Testosterone

Acne

Acne, also known as acne vulgaris, is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles.

See Dihydrotestosterone and Acne

Adipose tissue

Adipose tissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes.

See Dihydrotestosterone and Adipose tissue

Adolf Butenandt

Adolf Friedrich Johann Butenandt (24 March 1903 – 18 January 1995) was a German biochemist.

See Dihydrotestosterone and Adolf Butenandt

Adrenal gland

The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.

See Dihydrotestosterone and Adrenal gland

Adrenal steroid

Adrenal steroids are steroids that are derived from the adrenal glands.

See Dihydrotestosterone and Adrenal steroid

Adverse effect

An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery.

See Dihydrotestosterone and Adverse effect

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

See Dihydrotestosterone and Agonist

Allopregnanolone

Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. Dihydrotestosterone and Allopregnanolone are GABAA receptor positive allosteric modulators.

See Dihydrotestosterone and Allopregnanolone

Allosteric modulator

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli.

See Dihydrotestosterone and Allosteric modulator

Anabolic steroid

Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). Dihydrotestosterone and anabolic steroid are Anabolic–androgenic steroids.

See Dihydrotestosterone and Anabolic steroid

Anabolism

Anabolism is the set of metabolic pathways that construct macromolecules like DNA or RNA from smaller units.

See Dihydrotestosterone and Anabolism

Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. Dihydrotestosterone and androgen are Anabolic–androgenic steroids, hormones of the hypothalamus-pituitary-gonad axis and sex hormones.

See Dihydrotestosterone and Androgen

Androgen backdoor pathway

The androgen backdoor pathway is responsible for the synthesis of physiologically relevant androgens.

See Dihydrotestosterone and Androgen backdoor pathway

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, in the cytoplasm and then translocating into the nucleus.

See Dihydrotestosterone and Androgen receptor

Androgen-dependent condition

An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body. Dihydrotestosterone and androgen-dependent condition are testosterone.

See Dihydrotestosterone and Androgen-dependent condition

Androstane

Androstane is a C19 steroidal hydrocarbon with a gonane core. Dihydrotestosterone and Androstane are Anabolic–androgenic steroids and androstanes.

See Dihydrotestosterone and Androstane

Androstanedione

Androstanedione, also known as 5α-androstanedione or as 5α-androstane-3,17-dione, is a naturally occurring androstane (5α-androstane) steroid and an endogenous metabolite of androgens like testosterone, dihydrotestosterone (DHT), dehydroepiandrosterone (DHEA), and androstenedione. Dihydrotestosterone and Androstanedione are 5α-Reduced steroid metabolites, Anabolic–androgenic steroids and androstanes.

See Dihydrotestosterone and Androstanedione

Androstanolone

Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men. Dihydrotestosterone and Androstanolone are 5α-Reduced steroid metabolites, Anabolic–androgenic steroids, androstanes, GABAA receptor positive allosteric modulators, ketones and testosterone.

See Dihydrotestosterone and Androstanolone

Androstanolone propionate

Androstanolone propionate (brand name Pesomax), also known as stanolone propionate or dihydrotestosterone propionate (DHTP), as well as 5α-androstan-17β-ol-3-one 17β-propionate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that is marketed in Italy. Dihydrotestosterone and Androstanolone propionate are Anabolic–androgenic steroids and androstanes.

See Dihydrotestosterone and Androstanolone propionate

Androstanolone valerate

Androstanolone valerate (brand name Apeton), also known as stanolone valerate or dihydrotestosterone pentanoate, as well as 5α-androstan-17β-3-one 17β-valerate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester. Dihydrotestosterone and Androstanolone valerate are Anabolic–androgenic steroids and androstanes.

See Dihydrotestosterone and Androstanolone valerate

Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA). Dihydrotestosterone and Androstenedione are Anabolic–androgenic steroids and androstanes.

See Dihydrotestosterone and Androstenedione

Androsterone

Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. Dihydrotestosterone and Androsterone are 5α-Reduced steroid metabolites, Anabolic–androgenic steroids, androstanes and GABAA receptor positive allosteric modulators.

See Dihydrotestosterone and Androsterone

Antidepressant

Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.

See Dihydrotestosterone and Antidepressant

Anxiety

Anxiety is an emotion which is characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events.

See Dihydrotestosterone and Anxiety

Anxiolytic

An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety.

See Dihydrotestosterone and Anxiolytic

Aromatase

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.

See Dihydrotestosterone and Aromatase

Aromatization

Aromatization is a chemical reaction in which an aromatic system is formed from a single nonaromatic precursor.

See Dihydrotestosterone and Aromatization

Axilla

The axilla (axillae or axillas; also known as the armpit, underarm or oxter) is the area on the human body directly under the shoulder joint.

See Dihydrotestosterone and Axilla

Benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland.

See Dihydrotestosterone and Benign prostatic hyperplasia

Binding selectivity

In chemistry, binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

See Dihydrotestosterone and Binding selectivity

Bioassay

A bioassay is an analytical method to determine the potency or effect of a substance by its effect on living animals or plants (in vivo), or on living cells or tissues (in vitro).

See Dihydrotestosterone and Bioassay

Bioconjugation

Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule.

See Dihydrotestosterone and Bioconjugation

Biological activity

In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.

See Dihydrotestosterone and Biological activity

Biological half-life

Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.

See Dihydrotestosterone and Biological half-life

Biosynthesis

Biosynthesis, i.e., chemical synthesis occuring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex products.

See Dihydrotestosterone and Biosynthesis

Biotransformation

Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds.

See Dihydrotestosterone and Biotransformation

Birth defect

A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause.

See Dihydrotestosterone and Birth defect

Body hair

Body hair or androgenic hair is terminal hair that develops on the human body during and after puberty.

See Dihydrotestosterone and Body hair

Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

See Dihydrotestosterone and Brain

Breast development

Breast development, also known as mammogenesis, is a complex biological process in primates that takes place throughout a female's life.

See Dihydrotestosterone and Breast development

Buccal administration

Buccal administration is a topical route of administration by which drugs held or applied in the buccal area (in the cheek) diffuse through the oral mucosa (tissues which line the mouth) and enter directly into the bloodstream.

See Dihydrotestosterone and Buccal administration

Canada

Canada is a country in North America.

See Dihydrotestosterone and Canada

Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord.

See Dihydrotestosterone and Central nervous system

Chemical synthesis

Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products.

See Dihydrotestosterone and Chemical synthesis

Chest hair

Chest hair is hair that grows on the chest in the region between the neck and the abdomen.

See Dihydrotestosterone and Chest hair

Circulatory system

The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate.

See Dihydrotestosterone and Circulatory system

Clitoris

In amniotes, the clitoris (or;: clitorises or clitorides) is a female sex organ.

See Dihydrotestosterone and Clitoris

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) is a genetic disorder characterized by impaired production of cortisol in the adrenal glands.

See Dihydrotestosterone and Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Correlation coefficient

A correlation coefficient is a numerical measure of some type of linear correlation, meaning a statistical relationship between two variables.

See Dihydrotestosterone and Correlation coefficient

Cryptorchidism

Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum.

See Dihydrotestosterone and Cryptorchidism

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Dihydrotestosterone and Depression (mood)

Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

See Dihydrotestosterone and Derivative (chemistry)

Development of the gonads

The development of the gonads is part of the prenatal development of the reproductive system and ultimately forms the testicles in males and the ovaries in females.

See Dihydrotestosterone and Development of the gonads

Dialysis (chemistry)

In chemistry, dialysis is the process of separating molecules in solution by the difference in their rates of diffusion through a semipermeable membrane, such as dialysis tubing.

See Dihydrotestosterone and Dialysis (chemistry)

Disorders of sex development

Disorders of sex development (DSDs), also known as differences in sex development or variations in sex characteristics (VSC), are congenital conditions affecting the reproductive system, in which development of chromosomal, gonadal, or anatomical sex is atypical.

See Dihydrotestosterone and Disorders of sex development

Dissociation rate

The dissociation rate in chemistry, biochemistry, and pharmacology is the rate or speed at which a ligand dissociates from a protein, for instance, a receptor.

See Dihydrotestosterone and Dissociation rate

Dosage form

Dosage forms (also called unit doses) are pharmaceutical drug products in the form in which they are marketed for use, with a specific mixture of active ingredients and inactive components (excipients), in a particular configuration (such as a capsule shell, for example), and apportioned into a particular dose.

See Dihydrotestosterone and Dosage form

Double bond

In chemistry, a double bond is a covalent bond between two atoms involving four bonding electrons as opposed to two in a single bond.

See Dihydrotestosterone and Double bond

Dutasteride

Dutasteride, sold under the brand name Avodart among others, is a medication primarily used to treat the symptoms of a benign prostatic hyperplasia (BPH), an enlarged prostate not associated with cancer. Dihydrotestosterone and Dutasteride are androstanes.

See Dihydrotestosterone and Dutasteride

EC50

Half maximal effective concentration (EC50) is a measure of the concentration of a drug, antibody or toxicant which induces a biological response halfway between the baseline and maximum after a specified exposure time.

See Dihydrotestosterone and EC50

Embryo

An embryo is the initial stage of development for a multicellular organism.

See Dihydrotestosterone and Embryo

Endocrine system

The endocrine system is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs.

See Dihydrotestosterone and Endocrine system

Endogeny (biology)

Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.

See Dihydrotestosterone and Endogeny (biology)

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See Dihydrotestosterone and Enzyme

Epiandrosterone

Epiandrosterone, or isoandrosterone, also known as 3β-androsterone, 3β-hydroxy-5α-androstan-17-one, or 5α-androstan-3β-ol-17-one, is a steroid hormone with weak androgenic activity. Dihydrotestosterone and Epiandrosterone are 5α-Reduced steroid metabolites, Anabolic–androgenic steroids and androstanes.

See Dihydrotestosterone and Epiandrosterone

Epidermis

The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis.

See Dihydrotestosterone and Epidermis

Epididymis

The epididymis (epididymides or) is an elongated tubular structure attached to the posterior side of each one of the two male reproductive glands, the testicles.

See Dihydrotestosterone and Epididymis

Epitestosterone

Epitestosterone, or isotestosterone, also known as 17α-testosterone or as androst-4-en-17α-ol-3-one, is an endogenous steroid and an epimer of the androgen sex hormone testosterone. Dihydrotestosterone and Epitestosterone are androstanes.

See Dihydrotestosterone and Epitestosterone

Erectile dysfunction

Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.

See Dihydrotestosterone and Erectile dysfunction

Erection

An erection (clinically: penile erection or penile tumescence) is a physiological phenomenon in which the penis becomes firm, engorged, and enlarged.

See Dihydrotestosterone and Erection

Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

See Dihydrotestosterone and Ester

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. Dihydrotestosterone and Estradiol are animal reproductive system, hormones of the hypothalamus-pituitary-gonad axis and sex hormones.

See Dihydrotestosterone and Estradiol

Estrogen

Estrogen (oestrogen; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. Dihydrotestosterone and Estrogen are Cyclopentanols, hormones of the hypothalamus-pituitary-gonad axis, hormones of the testis, human hormones and sex hormones.

See Dihydrotestosterone and Estrogen

Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

See Dihydrotestosterone and Estrogen receptor

Estrogen receptor beta

Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear receptor which is activated by the sex hormone estrogen.

See Dihydrotestosterone and Estrogen receptor beta

Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

See Dihydrotestosterone and Europe

Excretion

Excretion is elimination of metabolic waste, which is an essential process in all organisms.

See Dihydrotestosterone and Excretion

Facial hair

Facial hair is hair grown on the face, usually on the chin, cheeks, and upper lip region.

See Dihydrotestosterone and Facial hair

Feminization (biology)

In biology and medicine, feminization is the development in an organism of physical characteristics that are usually unique to the females of the species.

See Dihydrotestosterone and Feminization (biology)

Fetus

A fetus or foetus (fetuses, foetuses, rarely feti or foeti) is the unborn offspring that develops from a mammal embryo.

See Dihydrotestosterone and Fetus

Finasteride

Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used to treat pattern hair loss and benign prostatic hyperplasia (BPH) in men. Dihydrotestosterone and Finasteride are androstanes.

See Dihydrotestosterone and Finasteride

First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

See Dihydrotestosterone and First pass effect

Functional group

In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions.

See Dihydrotestosterone and Functional group

GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

See Dihydrotestosterone and GABAA receptor

Güevedoce

In the Dominican Republic, güevedoces (from güevedoce, from Dominican Spanish label "testicles at twelve") are children with a specific intersex variation.

See Dihydrotestosterone and Güevedoce

Gel

A gel is a semi-solid that can have properties ranging from soft and weak to hard and tough.

See Dihydrotestosterone and Gel

Gender identity

Gender identity is the personal sense of one's own gender.

See Dihydrotestosterone and Gender identity

Gene

In biology, the word gene has two meanings.

See Dihydrotestosterone and Gene

Glucuronidation

Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.

See Dihydrotestosterone and Glucuronidation

Gynecomastia

Gynecomastia (also spelled gynaecomastia) is the abnormal non-cancerous enlargement of one or both breasts in males due to the growth of breast tissue as a result of a hormone imbalance between estrogens and androgens.

See Dihydrotestosterone and Gynecomastia

Hair follicle

The hair follicle is an organ found in mammalian skin.

See Dihydrotestosterone and Hair follicle

Hedonism

Hedonism refers to the prioritization of pleasure in one's lifestyle, actions, or thoughts.

See Dihydrotestosterone and Hedonism

High-performance liquid chromatography

High-performance liquid chromatography (HPLC), formerly referred to as high-pressure liquid chromatography, is a technique in analytical chemistry used to separate, identify, and quantify specific components in mixtures.

See Dihydrotestosterone and High-performance liquid chromatography

Hirsutism

Hirsutism is excessive body hair on parts of the body where hair is normally absent or minimal.

See Dihydrotestosterone and Hirsutism

Human hair growth

The growth of human hair occurs everywhere on the body except for the soles of the feet, the palms of the hands, the inside of the mouth, the lips, the backs of the ears, some external genital areas, the navel, and, apart from eyelashes, the eyelids.

See Dihydrotestosterone and Human hair growth

Human musculoskeletal system

The human musculoskeletal system (also known as the human locomotor system, and previously the activity system) is an organ system that gives humans the ability to move using their muscular and skeletal systems.

See Dihydrotestosterone and Human musculoskeletal system

Human serum albumin

Human serum albumin is the serum albumin found in human blood.

See Dihydrotestosterone and Human serum albumin

Hydrogenation

Hydrogenation is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.

See Dihydrotestosterone and Hydrogenation

Hydroxy group

In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom.

See Dihydrotestosterone and Hydroxy group

Hyperandrogenism

Hyperandrogenism is a medical condition characterized by high levels of androgens. Dihydrotestosterone and Hyperandrogenism are Anabolic–androgenic steroids.

See Dihydrotestosterone and Hyperandrogenism

Hypoactive sexual desire disorder

Hypoactive sexual desire disorder (HSDD), hyposexuality or inhibited sexual desire (ISD) is sometimes considered a sexual dysfunction, and is characterized as a lack or absence of sexual fantasies and desire for sexual activity, as judged by a clinician.

See Dihydrotestosterone and Hypoactive sexual desire disorder

Hypogonadism

Hypogonadism means diminished functional activity of the gonads—the testicles or the ovaries—that may result in diminished production of sex hormones.

See Dihydrotestosterone and Hypogonadism

Hypospermia

Hypospermia is a condition in which a man has an unusually low ejaculate (or semen) volume, less than 1.5 mL.

See Dihydrotestosterone and Hypospermia

Immunoassay

An immunoassay (IA) is a biochemical test that measures the presence or concentration of a macromolecule or a small molecule in a solution through the use of an antibody (usually) or an antigen (sometimes).

See Dihydrotestosterone and Immunoassay

Injection (medicine)

An injection (often and usually referred to as a "shot" in US English, a "jab" in UK English, or a "jag" in Scottish English and Scots) is the act of administering a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.

See Dihydrotestosterone and Injection (medicine)

Intersex

Intersex people are individuals born with any of several sex characteristics, including chromosome patterns, gonads, or genitals that, according to the Office of the United Nations High Commissioner for Human Rights, "do not fit typical binary notions of male or female bodies".

See Dihydrotestosterone and Intersex

Intracrine

Intracrine refers to a hormone that acts inside a cell, regulating intracellular events.

See Dihydrotestosterone and Intracrine

Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

See Dihydrotestosterone and Intramuscular injection

Ketone

In organic chemistry, a ketone is an organic compound with the structure, where R and R' can be a variety of carbon-containing substituents. Dihydrotestosterone and ketone are ketones.

See Dihydrotestosterone and Ketone

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Dihydrotestosterone and Kidney

Labcorp

Laboratory Corporation of America Holdings, more commonly known as Labcorp, is an American healthcare company headquartered in Burlington, North Carolina.

See Dihydrotestosterone and Labcorp

Labia

The labia are the major externally visible portions of the vulva.

See Dihydrotestosterone and Labia

Labia majora

In primates, and specifically in humans, the labia majora (labium majus), also known as the outer lips or outer labia, are two prominent longitudinal skin folds that extend downward and backward from the mons pubis to the perineum.

See Dihydrotestosterone and Labia majora

Libido

In psychology, libido (from the Latin, 'desire') is psychic drive or energy, usually conceived as sexual in nature, but sometimes conceived as including other forms of desire. Dihydrotestosterone and libido are testosterone.

See Dihydrotestosterone and Libido

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Dihydrotestosterone and Ligand (biochemistry)

Liquid chromatography–mass spectrometry

Liquid chromatography–mass spectrometry (LC–MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS).

See Dihydrotestosterone and Liquid chromatography–mass spectrometry

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Dihydrotestosterone and Liver

Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

See Dihydrotestosterone and Medication

Medicine

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health.

See Dihydrotestosterone and Medicine

Menopause

Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction.

See Dihydrotestosterone and Menopause

Menstrual cycle

The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible.

See Dihydrotestosterone and Menstrual cycle

Menstruation

Menstruation (also known as a period, among other colloquial terms) is the regular discharge of blood and mucosal tissue from the inner lining of the uterus through the vagina.

See Dihydrotestosterone and Menstruation

Metabolic intermediate

Metabolic intermediates are molecules that are the precursors or metabolites of biologically significant molecules.

See Dihydrotestosterone and Metabolic intermediate

Metabolic pathway

In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell.

See Dihydrotestosterone and Metabolic pathway

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

See Dihydrotestosterone and Metabolism

Metabolite

In biochemistry, a metabolite is an intermediate or end product of metabolism.

See Dihydrotestosterone and Metabolite

Micropenis

A micropenis is an unusually small penis.

See Dihydrotestosterone and Micropenis

MK-386

MK-386, also known as 4,7β-dimethyl-4-aza-5α-cholestan-3-one, is a synthetic, steroidal 5α-reductase inhibitor which was first reported in 1994 and was never marketed.

See Dihydrotestosterone and MK-386

Mood disorder

A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder where a disturbance in the person's mood is the main underlying feature.

See Dihydrotestosterone and Mood disorder

Muscle

Muscle is a soft tissue, one of the four basic types of animal tissue.

See Dihydrotestosterone and Muscle

Mutation

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA.

See Dihydrotestosterone and Mutation

Natural product

A natural product is a natural compound or substance produced by a living organism—that is, found in nature.

See Dihydrotestosterone and Natural product

Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.

See Dihydrotestosterone and Neurosteroid

Nootropic

Nootropics (or; but not or, which are common mispronunciations), colloquially brain supplements, smart drugs and cognitive enhancers, are natural, semisynthetic or synthetic compounds which purportedly improve cognitive functions, such as executive functions, attention or memory.

See Dihydrotestosterone and Nootropic

Oil

An oil is any nonpolar chemical substance that is composed primarily of hydrocarbons and is hydrophobic (does not mix with water) and lipophilic (mixes with other oils).

See Dihydrotestosterone and Oil

Oligospermia

Terms oligospermia, oligozoospermia, and low sperm count refer to semen with a low concentration of sperm and is a common finding in male infertility.

See Dihydrotestosterone and Oligospermia

Oral administration

| name.

See Dihydrotestosterone and Oral administration

Paracrine signaling

In cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby cells, altering the behaviour of those cells.

See Dihydrotestosterone and Paracrine signaling

Pattern hair loss

Pattern hair loss (also known as androgenetic alopecia (AGA)) is a hair loss condition that primarily affects the top and front of the scalp. Dihydrotestosterone and Pattern hair loss are testosterone.

See Dihydrotestosterone and Pattern hair loss

Penis

A penis (penises or penes) is a male sex organ that is used to inseminate female or hermaphrodite animals during copulation.

See Dihydrotestosterone and Penis

People of the Dominican Republic

Dominicans (Dominicanos) are an ethno-national people, a people of shared ancestry and culture, who have ancestral roots in the Dominican Republic.

See Dihydrotestosterone and People of the Dominican Republic

Performance-enhancing substance

Performance-enhancing substances, also known as performance-enhancing drugs (PEDs), are substances that are used to improve any form of activity performance in humans.

See Dihydrotestosterone and Performance-enhancing substance

Phallus

A phallus (phalli or phalluses) is a penis (especially when erect), an object that resembles a penis, or a mimetic image of an erect penis.

See Dihydrotestosterone and Phallus

Plasma protein binding

Plasma protein binding refers to the degree to which medications attach to blood proteins within the blood plasma.

See Dihydrotestosterone and Plasma protein binding

Polycystic ovary syndrome

Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age.

See Dihydrotestosterone and Polycystic ovary syndrome

Potency (pharmacology)

In pharmacology, potency or biological potency is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity.

See Dihydrotestosterone and Potency (pharmacology)

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Dihydrotestosterone and Pregnancy

Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Dihydrotestosterone and Progesterone are GABAA receptor positive allosteric modulators, hormones of the hypothalamus-pituitary-gonad axis, human hormones and sex hormones.

See Dihydrotestosterone and Progesterone

Prostate

The prostate is both an accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation.

See Dihydrotestosterone and Prostate

Prostate cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.

See Dihydrotestosterone and Prostate cancer

Protein isoform

A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

See Dihydrotestosterone and Protein isoform

Pseudohermaphroditism

Pseudohermaphroditism is an outdated term for when an individuals gonads was mismatched with their internal reproductive system and/or external genitalia.

See Dihydrotestosterone and Pseudohermaphroditism

Puberty

Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. Dihydrotestosterone and Puberty are animal reproductive system.

See Dihydrotestosterone and Puberty

Pubic hair

Pubic hair (or pubes) is terminal body hair that is found in the genital area of adolescent and adult humans.

See Dihydrotestosterone and Pubic hair

Radioimmunoassay

A radioimmunoassay (RIA) is an immunoassay that uses radiolabeled molecules in a stepwise formation of immune complexes.

See Dihydrotestosterone and Radioimmunoassay

Redox

Redox (reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change.

See Dihydrotestosterone and Redox

Reversible reaction

A reversible reaction is a reaction in which the conversion of reactants to products and the conversion of products to reactants occur simultaneously.

See Dihydrotestosterone and Reversible reaction

Reward system

The reward system (the mesocorticolimbic circuit) is a group of neural structures responsible for incentive salience (i.e., "wanting"; desire or craving for a reward and motivation), associative learning (primarily positive reinforcement and classical conditioning), and positively-valenced emotions, particularly ones involving pleasure as a core component (e.g., joy, euphoria and ecstasy).

See Dihydrotestosterone and Reward system

Scalp

The scalp is the area of the head where head hair grows.

See Dihydrotestosterone and Scalp

Scrotum

In most terrestrial mammals, the scrotum (scrotums or scrota; possibly from Latin scortum, meaning "hide" or "skin") or scrotal sac is a part of the external male genitalia located at the base of the penis.

See Dihydrotestosterone and Scrotum

Sebaceous gland

A sebaceous gland or oil gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals.

See Dihydrotestosterone and Sebaceous gland

Secondary sex characteristic

A secondary sex characteristic is a physical characteristic of an organism that is related to or derived from its sex, but not directly part of its reproductive system.

See Dihydrotestosterone and Secondary sex characteristic

Secretion

Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland.

See Dihydrotestosterone and Secretion

Self-harm

Self-harm is intentional conduct that is considered harmful to oneself.

See Dihydrotestosterone and Self-harm

Seminal vesicles

The seminal vesicles (also called vesicular glands or seminal glands) are a pair of convoluted tubular accessory glands that lie behind the urinary bladder of male mammals.

See Dihydrotestosterone and Seminal vesicles

Sex hormone

Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors. Dihydrotestosterone and sex hormone are animal reproductive system, hormones of the hypothalamus-pituitary-gonad axis and sex hormones.

See Dihydrotestosterone and Sex hormone

Sex hormone-binding globulin

Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens.

See Dihydrotestosterone and Sex hormone-binding globulin

Sex organ

A sex organ, also known as a reproductive organ, is a part of an organism that is involved in sexual reproduction.

See Dihydrotestosterone and Sex organ

Sexual differentiation

Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote.

See Dihydrotestosterone and Sexual differentiation

Sexual dysfunction

Sexual dysfunction is difficulty experienced by an individual or partners during any stage of normal sexual activity, including physical pleasure, desire, preference, arousal, or orgasm.

See Dihydrotestosterone and Sexual dysfunction

Sexual orientation

Sexual orientation is an enduring personal pattern of romantic attraction or sexual attraction (or a combination of these) to persons of the opposite sex or gender, the same sex or gender, or to both sexes or more than one gender.

See Dihydrotestosterone and Sexual orientation

Skin

Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.

See Dihydrotestosterone and Skin

Spermatogenesis

Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testicle.

See Dihydrotestosterone and Spermatogenesis

SRD5A1

3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene.

See Dihydrotestosterone and SRD5A1

SRD5A2

The human gene SRD5A2 encodes the 3-oxo-5α-steroid 4-dehydrogenase 2 enzyme, also known as 5α-reductase type 2 (5αR2), one of three isozymes of 5α-reductase.

See Dihydrotestosterone and SRD5A2

SRD5A3

Steroid 5-alpha-reductase 3, also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3, is an enzyme that in humans is encoded by the SRD5A3 gene.

See Dihydrotestosterone and SRD5A3

Steroid

A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.

See Dihydrotestosterone and Steroid

Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

See Dihydrotestosterone and Steroid hormone

Stress management

Stress management consists of a wide spectrum of techniques and psychotherapies aimed at controlling a person's level of stress, especially chronic stress, usually for the purpose of improving everyday functioning.

See Dihydrotestosterone and Stress management

Sublingual administration

Sublingual (abbreviated SL), from the Latin for "under the tongue", refers to the pharmacological route of administration by which substances diffuse into the blood through tissues under the tongue.

See Dihydrotestosterone and Sublingual administration

Sulfation

Sulfation is the chemical reaction that entails the addition of SO3 group.

See Dihydrotestosterone and Sulfation

Sweat gland

Sweat glands, also known as sudoriferous or sudoriparous glands,, are small tubular structures of the skin that produce sweat.

See Dihydrotestosterone and Sweat gland

Tablet (pharmacy)

A tablet (also known as a pill) is a pharmaceutical oral dosage form (oral solid dosage, or OSD) or solid unit dosage form.

See Dihydrotestosterone and Tablet (pharmacy)

Tanner scale

The Tanner scale (also known as the Tanner stages or sexual maturity rating (SMR)) is a scale of physical development as children transition into adolescence and then adulthood.

See Dihydrotestosterone and Tanner scale

Terminal hair

In humans, terminal hair is a variant of hair that is thick and long such as that growing on the scalp, as compared with vellus hair, colloquially known as peach fuzz, growing elsewhere.

See Dihydrotestosterone and Terminal hair

Testicle

A testicle or testis (testes) is the male gonad in all bilaterians, including humans.

See Dihydrotestosterone and Testicle

Testosterone

Testosterone is the primary male sex hormone and androgen in males. Dihydrotestosterone and Testosterone are Anabolic–androgenic steroids, androstanes, Cyclopentanols, GABAA receptor positive allosteric modulators, hormones of the hypothalamus-pituitary-gonad axis, hormones of the testis, human hormones and sex hormones.

See Dihydrotestosterone and Testosterone

Tissue (biology)

In biology, tissue is an assembly of similar cells and their extracellular matrix from the same embryonic origin that together carry out a specific function.

See Dihydrotestosterone and Tissue (biology)

Tolerability

Tolerability refers to the degree to which overt adverse effects of a drug can be tolerated by a patient.

See Dihydrotestosterone and Tolerability

Topical gels

Topical gels are a topical drug delivery dosage form commonly used in cosmetics and treatments for skin diseases because of their advantages over cream and ointment.

See Dihydrotestosterone and Topical gels

Transcortin

Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals.

See Dihydrotestosterone and Transcortin

Transdermal

Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.

See Dihydrotestosterone and Transdermal

Trends is a series of 16 review journals in a range of areas of biology and chemistry published under its Cell Press imprint by Elsevier.

See Dihydrotestosterone and Trends (journals)

United States

The United States of America (USA or U.S.A.), commonly known as the United States (US or U.S.) or America, is a country primarily located in North America.

See Dihydrotestosterone and United States

Urine

Urine is a liquid by-product of metabolism in humans and in many other animals.

See Dihydrotestosterone and Urine

Vagina

In mammals and other animals, the vagina (vaginas or vaginae) is the elastic, muscular reproductive organ of the female genital tract.

See Dihydrotestosterone and Vagina

Virilization

Virilization or masculinization is the biological development of adult male characteristics in young males or females. Dihydrotestosterone and Virilization are testosterone.

See Dihydrotestosterone and Virilization

Voice change

A voice change or voice mutation, sometimes referred to as a voice break or voice crack, commonly refers to the deepening of the voice of men as they reach puberty. Dihydrotestosterone and voice change are testosterone.

See Dihydrotestosterone and Voice change

17α-Hydroxyprogesterone

17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone.

See Dihydrotestosterone and 17α-Hydroxyprogesterone

3α-Androstanediol

3α-Androstanediol also known as 5α-androstane-3α,17β-diol and sometimes shortened in the literature to 3α-diol, is an endogenous steroid hormone and neurosteroid and a metabolite of androgens like dihydrotestosterone (DHT). Dihydrotestosterone and 3α-Androstanediol are 5α-Reduced steroid metabolites, Anabolic–androgenic steroids, androstanes, GABAA receptor positive allosteric modulators and selective ERβ agonists.

See Dihydrotestosterone and 3α-Androstanediol

3α-Hydroxysteroid dehydrogenase

3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans and other species, such as bacteria, fungi, plants, and so on.

See Dihydrotestosterone and 3α-Hydroxysteroid dehydrogenase

3β-Androstanediol

3β-Androstanediol, also known as 5α-androstane-3β,17β-diol, and sometimes shortened in the literature to 3β-diol, is an endogenous steroid hormone and a metabolite of androgens like dehydroepiandrosterone (DHEA) and dihydrotestosterone (DHT). Dihydrotestosterone and 3β-Androstanediol are 5α-Reduced steroid metabolites, androstanes and selective ERβ agonists.

See Dihydrotestosterone and 3β-Androstanediol

3β-Hydroxysteroid dehydrogenase

3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.

See Dihydrotestosterone and 3β-Hydroxysteroid dehydrogenase

5α-Dihydroprogesterone

5α-Dihydroprogesterone (5α-DHP, allopregnanedione, or 5α-pregnane-3,20-dione) is an endogenous progestogen and neurosteroid that is synthesized from progesterone. Dihydrotestosterone and 5α-Dihydroprogesterone are GABAA receptor positive allosteric modulators.

See Dihydrotestosterone and 5α-Dihydroprogesterone

5α-Pregnan-17α-ol-3,20-dione

5α-Pregnan-17α-ol-3,20-dione, also known as 17α-hydroxy-dihydroprogesterone (17‐OH-DHP) is an endogenous steroid, a metabolite of 17α-hydroxyprogesterone.

See Dihydrotestosterone and 5α-Pregnan-17α-ol-3,20-dione

5α-Pregnane-3α,17α-diol-20-one

5α-Pregnane-3α,17α-diol-20-one, also known as 17α-hydroxyallopregnanolone (17-OH-allo) is an endogenous steroid.

See Dihydrotestosterone and 5α-Pregnane-3α,17α-diol-20-one

5α-Reductase

5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.

See Dihydrotestosterone and 5α-Reductase

5α-Reductase 2 deficiency

5α-Reductase 2 deficiency (5αR2D) is an autosomal recessive condition caused by a mutation in SRD5A2, a gene encoding the enzyme 5α-reductase type 2 (5αR2).

See Dihydrotestosterone and 5α-Reductase 2 deficiency

5α-Reductase inhibitor

5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss.

See Dihydrotestosterone and 5α-Reductase inhibitor

See also

5α-Reduced steroid metabolites

Cyclopentanols

Hormones of the hypothalamus-pituitary-gonad axis

Hormones of the testis

Human hormones

Selective ERβ agonists

Sex hormones

Testosterone

References

[1] https://en.wikipedia.org/wiki/Dihydrotestosterone

Also known as 17-Hydroxyandrostan-3-one, 5a-DHT, 5a-Dihydrotestosterone, 5alpha-dihydrotestosterone, 5α-Androstan-17β-ol-3-one, 5α-DHT, 5α-Dihydrotestosterone, Androstan-17β-ol-3-one, Dihydrotestosteron.

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