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Hydromorphone

Index Hydromorphone

Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe pain. [1]

Table of Contents

  1. 108 relations: Abuse, Activated carbon, Administrative Controlled Substances Code Number, Adverse effect, Agonist, Alcohol (drug), Anesthetic, Antihistamine, Aqueous solution, Barbiturate, Benzodiazepine, Benzophenone, Beta blocker, Betäubungsmittelgesetz, Biliary tract, Bioavailability, Blood–brain barrier, Breastfeeding, Brompheniramine, Cancer, Capital punishment in Ohio, Central nervous system, Chloral hydrate, Chlorphenamine, Clonidine, Cochrane (organisation), Codeine, Cognitive disorder, Constipation, Controlled Substances Act, Diazepam, Diário Oficial da União, Dihydromorphine, Dimenhydrinate, Diphenhydramine, Dizziness, Dose (biochemistry), Dysphoria, Endocrine disease, Epidural administration, Equianalgesic, Euphoria, Gastrointestinal tract, Generic drug, Glutethimide, Hallucination, Headache, Heroin, Hydrochloride, Hydrocodone, ... Expand index (58 more) »

Abuse

Abuse is the improper usage or treatment of a person or thing, often to unfairly or improperly gain benefit.

See Hydromorphone and Abuse

Activated carbon

Activated carbon, also called activated charcoal, is a form of carbon commonly used to filter contaminants from water and air, among many other uses. Hydromorphone and activated carbon are world Health Organization essential medicines.

See Hydromorphone and Activated carbon

Administrative Controlled Substances Code Number

Administrative Controlled Substances Code Number (ACSCN) is a number assigned to drugs listed on the schedules created by the US Controlled Substances Act (CSA).

See Hydromorphone and Administrative Controlled Substances Code Number

Adverse effect

An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery.

See Hydromorphone and Adverse effect

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

See Hydromorphone and Agonist

Alcohol (drug)

Alcohol, sometimes referred to by the chemical name ethanol, is one of the most widely used and abused psychoactive drugs in the world and falls under the depressant category. Hydromorphone and Alcohol (drug) are Euphoriants.

See Hydromorphone and Alcohol (drug)

Anesthetic

An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness.

See Hydromorphone and Anesthetic

Antihistamine

Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies.

See Hydromorphone and Antihistamine

Aqueous solution

An aqueous solution is a solution in which the solvent is water.

See Hydromorphone and Aqueous solution

Barbiturate

Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. Hydromorphone and Barbiturate are German inventions.

See Hydromorphone and Barbiturate

Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

See Hydromorphone and Benzodiazepine

Benzophenone

Benzophenone is a naturally occurring organic compound with the formula (C6H5)2CO, generally abbreviated Ph2CO.

See Hydromorphone and Benzophenone

Beta blocker

Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms (arrhythmia), and to protect the heart from a second heart attack after a first heart attack (secondary prevention).

See Hydromorphone and Beta blocker

Betäubungsmittelgesetz

The Betäubungsmittelgesetz (BtMG; Narcotics Law) is the controlled substances law of Germany.

See Hydromorphone and Betäubungsmittelgesetz

Biliary tract

The biliary tract (also biliary tree or biliary system) refers to the liver, gallbladder and bile ducts, and how they work together to make, store and secrete bile.

See Hydromorphone and Biliary tract

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

See Hydromorphone and Bioavailability

Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood.

See Hydromorphone and Blood–brain barrier

Breastfeeding

Breastfeeding, variously known as chestfeeding or nursing, is the process where breast milk is fed to a child.

See Hydromorphone and Breastfeeding

Brompheniramine

Brompheniramine, sold under the brand name Dimetapp among others, is a first-generation antihistamine drug of the propylamine (alkylamine) class.

See Hydromorphone and Brompheniramine

Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

See Hydromorphone and Cancer

Capital punishment in Ohio

Capital punishment is a legal penalty in the U.S. state of Ohio, although all executions have been suspended indefinitely by Governor Mike DeWine until a replacement for lethal injection is chosen by the Ohio General Assembly.

See Hydromorphone and Capital punishment in Ohio

Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord.

See Hydromorphone and Central nervous system

Chloral hydrate

Chloral hydrate is a geminal diol with the formula.

See Hydromorphone and Chloral hydrate

Chlorphenamine

Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever).

See Hydromorphone and Chlorphenamine

Clonidine

Clonidine, sold under the brand name Catapres among others, is an α2A-adrenergic agonist medication used to treat high blood pressure, ADHD, drug withdrawal (alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions.

See Hydromorphone and Clonidine

Cochrane (organisation)

Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers.

See Hydromorphone and Cochrane (organisation)

Codeine

Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. Hydromorphone and Codeine are world Health Organization essential medicines.

See Hydromorphone and Codeine

Cognitive disorder

Cognitive disorders (CDs), also known as neurocognitive disorders (NCDs), are a category of mental health disorders that primarily affect cognitive abilities including learning, memory, perception, and problem-solving.

See Hydromorphone and Cognitive disorder

Constipation

Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass.

See Hydromorphone and Constipation

Controlled Substances Act

The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.

See Hydromorphone and Controlled Substances Act

Diazepam

Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. Hydromorphone and Diazepam are Euphoriants and world Health Organization essential medicines.

See Hydromorphone and Diazepam

Diário Oficial da União

The Diário Oficial da União (literally Official Diary of the Union), abbreviated DOU, is the official journal of the federal government of Brazil.

See Hydromorphone and Diário Oficial da União

Dihydromorphine

Dihydromorphine (Paramorfan, Paramorphan) is a semi-synthetic opioid structurally related to and derived from morphine. Hydromorphone and Dihydromorphine are Euphoriants, mu-opioid receptor agonists, Phenols and semisynthetic opioids.

See Hydromorphone and Dihydromorphine

Dimenhydrinate

Dimenhydrinate, sold under the brand name Dramamine, among others, is an over-the-counter medication used to treat motion sickness and nausea.

See Hydromorphone and Dimenhydrinate

Diphenhydramine

Diphenhydramine (DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold.

See Hydromorphone and Diphenhydramine

Dizziness

Dizziness is an imprecise term that can refer to a sense of disorientation in space, vertigo, or lightheadedness.

See Hydromorphone and Dizziness

Dose (biochemistry)

A dose is a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit.

See Hydromorphone and Dose (biochemistry)

Dysphoria

Dysphoria is a profound state of unease or dissatisfaction.

See Hydromorphone and Dysphoria

Endocrine disease

Endocrine diseases are disorders of the endocrine system.

See Hydromorphone and Endocrine disease

Epidural administration

Epidural administration (from Ancient Greek ἐπί, "upon" + dura mater) is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord.

See Hydromorphone and Epidural administration

Equianalgesic

An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain).

See Hydromorphone and Equianalgesic

Euphoria

Euphoria is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. Hydromorphone and Euphoria are Euphoriants.

See Hydromorphone and Euphoria

Gastrointestinal tract

The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.

See Hydromorphone and Gastrointestinal tract

Generic drug

A generic drug (or simply generic) is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents.

See Hydromorphone and Generic drug

Glutethimide

Glutethimide is a hypnotic sedative that was introduced by Ciba in 1954 as a safe alternative to barbiturates to treat insomnia.

See Hydromorphone and Glutethimide

Hallucination

A hallucination is a perception in the absence of an external stimulus that has the compelling sense of reality.

See Hydromorphone and Hallucination

Headache

Headache, also known as cephalalgia, is the symptom of pain in the face, head, or neck.

See Hydromorphone and Headache

Heroin

Heroin, also known as diacetylmorphine and diamorphine among other names, is a morphinan opioid substance synthesized from the dried latex of the Papaver somniferum plant; it is mainly used as a recreational drug for its euphoric effects. Hydromorphone and Heroin are Euphoriants, mu-opioid receptor agonists and semisynthetic opioids.

See Hydromorphone and Heroin

Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

See Hydromorphone and Hydrochloride

Hydrocodone

Hydrocodone, also known as dihydrocodeinone, is a semisynthetic opioid used to treat pain and as a cough suppressant. Hydromorphone and Hydrocodone are Euphoriants, German inventions, ketones, mu-opioid receptor agonists and semisynthetic opioids.

See Hydromorphone and Hydrocodone

Hydrogenation

Hydrogenation is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.

See Hydromorphone and Hydrogenation

Hydromorphinol

Hydromorphinol (RAM-320, 14-Hydroxydihydromorphine), is an opiate analogue that is a derivative of morphine, where the 14-position has been hydroxylated and the 7,8- double bond saturated. Hydromorphone and Hydromorphinol are mu-opioid receptor agonists, Phenols and semisynthetic opioids.

See Hydromorphone and Hydromorphinol

Hyperalgesia

Hyperalgesia (or; 'hyper' from Greek ὑπέρ (huper, “over”), '-algesia' from Greek algos, ἄλγος (pain)) is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus.

See Hydromorphone and Hyperalgesia

Hyperglycemia

Hyperglycemia or Hyperglycaemia is a condition in which an excessive amount of glucose circulates in the blood plasma.

See Hydromorphone and Hyperglycemia

Hypnotic

Hypnotic (from Greek Hypnos, sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy.

See Hydromorphone and Hypnotic

Hypogonadism

Hypogonadism means diminished functional activity of the gonads—the testicles or the ovaries—that may result in diminished production of sex hormones.

See Hydromorphone and Hypogonadism

Hypotension

Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure.

See Hydromorphone and Hypotension

Hypoventilation

Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed respiratory gas exchange.

See Hydromorphone and Hypoventilation

Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

See Hydromorphone and Intramuscular injection

Intrathecal administration

Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF).

See Hydromorphone and Intrathecal administration

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Hydromorphone and Intravenous therapy

Itch

An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch.

See Hydromorphone and Itch

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Hydromorphone and Kidney

Laudanum

Laudanum is a tincture of opium containing approximately 10% powdered opium by weight (the equivalent of 1% morphine).

See Hydromorphone and Laudanum

Lethal injection

Lethal injection is the practice of injecting one or more drugs into a person (typically a barbiturate, paralytic, and potassium solution) for the express purpose of causing rapid death.

See Hydromorphone and Lethal injection

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Hydromorphone and Ligand (biochemistry)

Lightheadedness

Lightheadedness is a common and typically unpleasant sensation of dizziness or a feeling that one may faint.

See Hydromorphone and Lightheadedness

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Hydromorphone and Liver

Methadone

Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid use disorder. Hydromorphone and Methadone are Euphoriants, German inventions, ketones, mu-opioid receptor agonists and world Health Organization essential medicines.

See Hydromorphone and Methadone

Methylene group

A methylene group is any part of a molecule that consists of two hydrogen atoms bound to a carbon atom, which is connected to the remainder of the molecule by two single bonds.

See Hydromorphone and Methylene group

Midazolam

Midazolam, sold under the brand name Versed among others, is a benzodiazepine medication used for anesthesia, premedication before surgical anesthesia, and procedural sedation, and to treat severe agitation. Hydromorphone and Midazolam are world Health Organization essential medicines.

See Hydromorphone and Midazolam

Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

See Hydromorphone and Monoamine oxidase inhibitor

Morphinan

Morphinan is the prototype chemical structure of a large chemical class of psychoactive drugs, consisting of opiate analgesics, cough suppressants, and dissociative hallucinogens, among others.

See Hydromorphone and Morphinan

Morphine

Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (Papaver somniferum). Hydromorphone and Morphine are Euphoriants, German inventions, mu-opioid receptor agonists and world Health Organization essential medicines.

See Hydromorphone and Morphine

Morphinone

Morphinone is an opioid that is the intermediate when morphine is being converted to hydromorphone (trade name Dilaudid). Hydromorphone and Morphinone are mu-opioid receptor agonists, Phenols and semisynthetic opioids.

See Hydromorphone and Morphinone

Morphinone reductase

Morphinone reductase is an enzyme which catalyzes the NADH-dependent saturation of the carbon-carbon double bond of morphinone and codeinone, yielding hydromorphone and hydrocodone respectively.

See Hydromorphone and Morphinone reductase

Myoclonus

Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular.

See Hydromorphone and Myoclonus

Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

See Hydromorphone and Nausea

Ohio Department of Rehabilitation and Correction

The Ohio Department of Rehabilitation and Correction (DRC or ODRC) is the administrative department of the Ohio state government responsible for oversight of Ohio State Correctional Facilities, along with its Incarcerated Individuals.

See Hydromorphone and Ohio Department of Rehabilitation and Correction

Opioid

Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant.

See Hydromorphone and Opioid

Opioid receptor

Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands.

See Hydromorphone and Opioid receptor

Opioid withdrawal

Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden withdrawal or reduction of opioids where previous usage has been heavy and prolonged.

See Hydromorphone and Opioid withdrawal

Oppenauer oxidation

Oppenauer oxidation, named after, is a gentle method for selectively oxidizing secondary alcohols to ketones.

See Hydromorphone and Oppenauer oxidation

Oral administration

| name.

See Hydromorphone and Oral administration

Oxycodone

Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a semi-synthetic opioid used medically for treatment of moderate to severe pain. Hydromorphone and Oxycodone are Euphoriants, German inventions, mu-opioid receptor agonists, semisynthetic opioids and world Health Organization essential medicines.

See Hydromorphone and Oxycodone

Oxymorphone

Oxymorphone (sold under the brand names Numorphan and Opana among others) is a highly potent opioid analgesic indicated for treatment of severe pain. Hydromorphone and Oxymorphone are Euphoriants, German inventions, ketones, mu-opioid receptor agonists, Phenols and semisynthetic opioids.

See Hydromorphone and Oxymorphone

Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

See Hydromorphone and Pain

Pain management

Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging.

See Hydromorphone and Pain management

Perspiration

Perspiration, also known as sweat, is the fluid secreted by sweat glands in the skin of mammals.

See Hydromorphone and Perspiration

Pethidine

Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a fully synthetic opioid pain medication of the phenylpiperidine class. Hydromorphone and Pethidine are Euphoriants and mu-opioid receptor agonists.

See Hydromorphone and Pethidine

Phenothiazine

Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C6H4)2NH and is related to the thiazine-class of heterocyclic compounds.

See Hydromorphone and Phenothiazine

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Hydromorphone and Pregnancy

Promethazine

Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea.

See Hydromorphone and Promethazine

Psychomotor agitation

Psychomotor agitation is a symptom in various disorders and health conditions.

See Hydromorphone and Psychomotor agitation

Redox

Redox (reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change.

See Hydromorphone and Redox

Route of administration

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body.

See Hydromorphone and Route of administration

Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

See Hydromorphone and Sedation

Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

See Hydromorphone and Sedative

Seizure

A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

See Hydromorphone and Seizure

Serotonin syndrome

Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs.

See Hydromorphone and Serotonin syndrome

Shortness of breath

Shortness of breath (SOB), known as dyspnea (in AmE) or dyspnoea (in BrE), is an uncomfortable feeling of not being able to breathe well enough.

See Hydromorphone and Shortness of breath

Subcutaneous administration

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion.

See Hydromorphone and Subcutaneous administration

The New York Times

The New York Times (NYT) is an American daily newspaper based in New York City.

See Hydromorphone and The New York Times

Tremor

A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.

See Hydromorphone and Tremor

Vomiting

Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

See Hydromorphone and Vomiting

WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. Hydromorphone and WHO Model List of Essential Medicines are world Health Organization essential medicines.

See Hydromorphone and WHO Model List of Essential Medicines

Wittig reaction

The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with a triphenyl phosphonium ylide called a Wittig reagent. Hydromorphone and Wittig reaction are German inventions.

See Hydromorphone and Wittig reaction

6-Methylenedihydrodesoxymorphine

6-Methylenedihydrodesoxymorphine (6-MDDM) is an opiate analogue structurally related to desomorphine that is a derivative of hydromorphone, where the 6-ketone group has been replaced by a methylidene group. Hydromorphone and 6-Methylenedihydrodesoxymorphine are mu-opioid receptor agonists, Phenols and semisynthetic opioids.

See Hydromorphone and 6-Methylenedihydrodesoxymorphine

References

[1] https://en.wikipedia.org/wiki/Hydromorphone

Also known as ATC code N02AA03, ATCvet code QN02AA03, Dalottid, Delaudin, DiMo, Dihydromorphinone, Dilauded, Dilaudid, Dilaudid Oros, Dilaudid-hp, Dilaudide, Dilauid, Dillotid, Dillotted, Diloded, Dilotid, Dilotted, Dilottid, Diluadid, Diluaid, Dimorphone, Exalgo, Hydal, Hydromorfan, Hydromorphan, Hydromorphine, Hydromorphone Hydrochloride, Hymorfan, Hymorphan, Idromorfone, Jurnista, Laudacon, Laudicon, Novolaudon, Opidol, Palladon, Palladone, Paramorphan, Sophidone.

, Hydrogenation, Hydromorphinol, Hyperalgesia, Hyperglycemia, Hypnotic, Hypogonadism, Hypotension, Hypoventilation, Intramuscular injection, Intrathecal administration, Intravenous therapy, Itch, Kidney, Laudanum, Lethal injection, Ligand (biochemistry), Lightheadedness, Liver, Methadone, Methylene group, Midazolam, Monoamine oxidase inhibitor, Morphinan, Morphine, Morphinone, Morphinone reductase, Myoclonus, Nausea, Ohio Department of Rehabilitation and Correction, Opioid, Opioid receptor, Opioid withdrawal, Oppenauer oxidation, Oral administration, Oxycodone, Oxymorphone, Pain, Pain management, Perspiration, Pethidine, Phenothiazine, Pregnancy, Promethazine, Psychomotor agitation, Redox, Route of administration, Sedation, Sedative, Seizure, Serotonin syndrome, Shortness of breath, Subcutaneous administration, The New York Times, Tremor, Vomiting, WHO Model List of Essential Medicines, Wittig reaction, 6-Methylenedihydrodesoxymorphine.