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Ibotenic acid

Index Ibotenic acid

Ibotenic acid or (S)-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid, also referred to as ibotenate, is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. [1]

51 relations: Agonist, Amanita muscaria, AMPA receptor, Anticholinergic, Apoptosis, Ataxia, Atropine, Benzodiazepine, CAMK, Central nervous system, Chemical compound, Decarboxylation, Delirium, Dentate gyrus, Dizocilpine, Euphoria, GABAA receptor, GABAA-rho receptor, Gastric lavage, Glutamate (neurotransmitter), Glutamate receptor, Granule cell, Hippocampus, Intravenous therapy, Kainate receptor, Lesion, Lethargy, Long-term potentiation, Metabotropic glutamate receptor, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 5, Muscimol, Mushroom, N-Methyl-D-aspartic acid, Neurotoxin, Neurotransmitter, NMDA receptor, Obtundation, Perforant path, Prodrug, Psychoactive drug, Pyramidal cell, Quisqualic acid, Reactive oxygen species, Retrograde amnesia, Scientific method, Sedation, Structural analog, ..., Synaptic plasticity. Expand index (1 more) »

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Amanita muscaria

Amanita muscaria, commonly known as the fly agaric or fly amanita, is a basidiomycete mushroom, one of many in the genus Amanita.

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AMPA receptor

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS).

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Anticholinergic

An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Ataxia

Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.

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Atropine

Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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CAMK

CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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Decarboxylation

Decarboxylation is a chemical reaction that removes a carboxyl group and releases carbon dioxide (CO2).

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Delirium

Delirium, also known as acute confusional state, is an organically caused decline from a previously baseline level of mental function.

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Dentate gyrus

The dentate gyrus is part of a brain region known as the hippocampus (part of the hippocampal formation).

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Dizocilpine

Dizocilpine (INN), also known as MK-801, is a noncompetitive antagonist of the ''N''-Methyl-D-aspartate (NMDA) receptor, a glutamate receptor, discovered by a team at Merck in 1982.

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Euphoria

Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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GABAA-rho receptor

The GABAA-rho receptor (previously known as the GABAC receptor) is a subclass of GABAA receptors composed entirely of rho (ρ) subunits.

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Gastric lavage

Gastric lavage, also commonly called stomach pumping or gastric irrigation, is the process of cleaning out the contents of the stomach.

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Glutamate (neurotransmitter)

In neuroscience, glutamate refers to the anion of glutamic acid in its role as a neurotransmitter: a chemical that nerve cells use to send signals to other cells.

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Glutamate receptor

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.

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Granule cell

The name granule cell has been used by anatomists for a number of different types of neuron whose only common feature is that they all have very small cell bodies.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Kainate receptor

Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate.

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Lesion

A lesion is any abnormal damage or change in the tissue of an organism, usually caused by disease or trauma.

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Lethargy

Lethargy is a state of tiredness, weariness, fatigue, or lack of energy.

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Long-term potentiation

In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity.

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Metabotropic glutamate receptor

The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process.

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Metabotropic glutamate receptor 1

The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein.

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Metabotropic glutamate receptor 2

Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene.

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Metabotropic glutamate receptor 3

Metabotropic glutamate receptor 3 is a protein that in humans is encoded by the GRM3 gene.

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Metabotropic glutamate receptor 5

Metabotropic glutamate receptor 5 is a G protein-coupled receptor that in humans is encoded by the GRM5 gene.

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Muscimol

Muscimol (also known as agarin or pantherine) is one of the principal psychoactive constituents of Amanita muscaria and related species of mushroom.

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Mushroom

A mushroom, or toadstool, is the fleshy, spore-bearing fruiting body of a fungus, typically produced above ground on soil or on its food source.

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N-Methyl-D-aspartic acid

N-Methyl-D-aspartic acid or N-Methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

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Neurotoxin

Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity).

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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Obtundation

Obtundation refers to less than full alertness (altered level of consciousness), typically as a result of a medical condition or trauma.

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Perforant path

In the brain, the perforant path or perforant pathway, provides a connectional route from the entorhinal cortex to all fields of the hippocampal formation, including the dentate gyrus, all CA fields (including CA1), and the subiculum.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Psychoactive drug

A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.

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Pyramidal cell

Pyramidal cells, or (pyramidal neurons), are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala.

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Quisqualic acid

Quisqualic acid is an agonist of the AMPA, kainate, and group I metabotropic glutamate receptors.

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Reactive oxygen species

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.

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Retrograde amnesia

Retrograde amnesia (RA) is a loss of memory-access to events that occurred, or information that was learned, before an injury or the onset of a disease.

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Scientific method

Scientific method is an empirical method of knowledge acquisition, which has characterized the development of natural science since at least the 17th century, involving careful observation, which includes rigorous skepticism about what one observes, given that cognitive assumptions about how the world works influence how one interprets a percept; formulating hypotheses, via induction, based on such observations; experimental testing and measurement of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings.

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Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

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Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

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Synaptic plasticity

In neuroscience, synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity.

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Redirects here:

Ibotanic acid, Ibotenate, Ibotenic Acid.

References

[1] https://en.wikipedia.org/wiki/Ibotenic_acid

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