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Macrophage

Index Macrophage

Macrophages (big eaters, from Greek μακρός (makrós). [1]

159 relations: Adaptive immune system, Adenoviridae, Adipocyte, Adipose tissue, Adipose tissue macrophages, Alveolar macrophage, Amoeboid movement, Angiogenesis, Angiotensin, Anti-inflammatory, Antibody, Antigen, Antigen presentation, Apoptosis, Arginine, Assimilation (biology), Atheroma, Atherosclerosis, Autophagy, Élie Metchnikoff, Blood, Blood vessel, Bone, Bone marrow, Brucellosis, CCL2, CCR2, CD14, CD154, CD31, CD40 (protein), CD64 (biology), CD68, Cell membrane, Central nervous system, Chemotaxis, Chemotherapy, Chikungunya, Chronic granulomatous disease, Conidium, Connective tissue, Critical Reviews in Immunology, Cytokine, Cytoplasm, Debridement, Dendritic cell, Dermal fibroblast, EMR1, Endothelium, Enzyme, ..., Eosinophil, Epithelioid cell, Escherichia coli, Extracellular matrix, Ferritin, Ferroportin, Flow cytometry, Foam cell, Fungus, Giant cell, Granuloma, Hepcidin, Histiocyte, HIV, Hofbauer cell, Homeostasis, Hypoxia (medical), Immune system, Immunohistochemistry, Immunotherapy, Inflammation, Inflammatory bowel disease, Innate immune system, Integrin alpha M, Interferon gamma, Interleukin 10, Interleukin 12, Interleukin 4, Interleukin 6, Interleukin-1 family, Intraglomerular mesangial cell, Iron supplement, Kidney, Kupffer cell, Legionella pneumophila, Legionnaires' disease, Leishmania, Leishmaniasis, Leukocyte extravasation, Leydig cell, Lipopolysaccharide, Liver, Lung, Lymph node, Lymphocyte, Lymphokine, Lysosome, Lysozyme, Macromolecule, Macrophage colony-stimulating factor, Macrophage-1 antigen, Major histocompatibility complex, Melanin, Melanocyte, Microbiota, Microglia, Microorganism, Monocyte, Monokine, Mononuclear phagocyte system, Mouse, Mycobacterium tuberculosis, Myocardial infarction, Necrosis, Neutrophil, NF-κB, Nitric oxide, Obesity, Opsonin, Ornithine, Osteoclast, Oxygen, Paracrine signalling, Parasitism, Pathogen, Pathogen-associated molecular pattern, Peritoneal cavity, Peyer's patch, Phagocyte, Phagocytosis, Phagosome, Pharmacokinetics, Phi, Pigment, Placenta, Pseudopodia, Pulmonary alveolus, Radiation therapy, Red blood cell, Red pulp, Regeneration (biology), Regulatory macrophages, Salamander, Sinusoid (blood vessel), Spleen, Surgery, Systemic inflammation, T cell, T helper cell, Targeted therapy, Tattoo, Transforming growth factor beta, Trypan blue, Tuberculosis, Tumor necrosis factor alpha, Tumor necrosis factor superfamily, Vascular endothelial growth factor, White blood cell, Wound healing. Expand index (109 more) »

Adaptive immune system

The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

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Adenoviridae

Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome.

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Adipocyte

Adipocytes, also known as lipocytes and fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat.

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Adipose tissue

In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes.

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Adipose tissue macrophages

Adipose tissue macrophages (abbr. ATMs) comprise tissue resident macrophages present in adipose tissue.

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Alveolar macrophage

An alveolar macrophage (or dust cell) is a type of macrophage found in the pulmonary alveolus, near the pneumocytes, but separated from the wall.

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Amoeboid movement

Amoeboid movement is the most common mode of locomotion in eukaryotic cells.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Angiotensin

Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.

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Anti-inflammatory

Anti-inflammatory, or antiinflammatory, refers to the property of a substance or treatment that reduces inflammation or swelling.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Antigen presentation

Antigen presentation describes a vital immune process which is essential for T cell immune response triggering.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Arginine

Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.

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Assimilation (biology)

Biological assimilation, or bio-assimilation, is the combination of two processes to supply cells with nutrients.

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Atheroma

An atheroma is a reversible accumulation of degenerative material in the inner layer of an artery wall.

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Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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Autophagy

Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning "self-devouring" and κύτος kýtos, meaning "hollow") is the natural, regulated, destructive mechanism of the cell that disassembles unnecessary or dysfunctional components.

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Élie Metchnikoff

Ilya Ilyich Mechnikov (Илья́ Ильи́ч Ме́чников, also written as Élie Metchnikoff; 15 July 1916) was a Russian zoologist best known for his pioneering research in immunology.

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Blood

Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Bone

A bone is a rigid organ that constitutes part of the vertebrate skeleton.

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Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

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Brucellosis

Brucellosis is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions.

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CCL2

For the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2.

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CCR2

C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. CCR2 is a chemokine receptor.

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CD14

CD14 (cluster of differentiation 14) is a human gene.

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CD154

CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules.

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CD31

Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17.

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CD40 (protein)

Cluster of differentiation 40, CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation.

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CD64 (biology)

CD64 (Cluster of Differentiation 64) is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity.

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CD68

CD68 ('''C'''luster of '''D'''ifferentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia).

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Chemotaxis

Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Chikungunya

Chikungunya is an infection caused by the chikungunya virus (CHIKV).

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Chronic granulomatous disease

Chronic granulomatous disease (CGD) (also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.

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Conidium

A conidium (plural conidia), sometimes termed an asexual chlamydospore or chlamydoconidium (plural chlamydoconidia), is an asexual, non-motile spore of a fungus.

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Connective tissue

Connective tissue (CT) is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue.

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Critical Reviews in Immunology

Critical Reviews in Immunology is a bimonthly scientific journal published by Begell House covering the field of immunology.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Debridement

Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue.

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Dendritic cell

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.

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Dermal fibroblast

Dermal fibroblasts are cells within the dermis layer of skin which are responsible for generating connective tissue and allowing the skin to recover from injury.

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EMR1

EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Eosinophil

Eosinophils sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While they are released into the bloodstream as neutrophils are, eosinophils reside in tissue They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovary, uterus, spleen, and lymph nodes, but not in the lung, skin, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.

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Epithelioid cell

Epithelioid histiocytes (Epithelioid cells) are activated macrophages resembling epithelial cells: elongated, with finely granular, pale eosinophilic (pink) cytoplasm and central, ovoid nucleus (oval or elongate), which is less dense than that of a lymphocyte.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Extracellular matrix

In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.

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Ferritin

Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion.

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Ferroportin

Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene, and is part of the Ferroportin (Fpn) Family.

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Flow cytometry

In biotechnology, flow cytometry is a laser- or impedance-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them through an electronic detection apparatus.

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Foam cell

Foam cells are the fat-laden M2 macrophages that serve as the hallmark of early stage atherosclerotic lesion formation.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Giant cell

A giant cell (multinucleated giant cell, multinucleate giant cell) is a mass formed by the union of several distinct cells (usually macrophages), often forming a granuloma.

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Granuloma

Granuloma is an inflammation found in many diseases.

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Hepcidin

Hepcidin is a protein that in humans is encoded by the HAMP gene.

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Histiocyte

A histiocyte is an animal cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system).

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HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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Hofbauer cell

Hofbauer cells are oval eosinophilic histiocytes with granules and vacuoles found in the placenta, which are of mesenchymal origin, in mesoderm of the chorionic villus, particularly numerous in early pregnancy.

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Homeostasis

Homeostasis is the tendency of organisms to auto-regulate and maintain their internal environment in a stable state.

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Hypoxia (medical)

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunohistochemistry

Immunohistochemistry (IHC) involves the process of selectively imaging antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.

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Immunotherapy

Immunotherapy is the "treatment of disease by inducing, enhancing, or suppressing an immune response".

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

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Innate immune system

The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.

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Integrin alpha M

Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3).

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Interferon gamma

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.

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Interleukin 10

Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.

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Interleukin 12

Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.

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Interleukin 4

The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.

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Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

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Interleukin-1 family

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults.

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Intraglomerular mesangial cell

Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney.

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Iron supplement

Iron supplements, also known as iron salts and iron pills, are a number of iron formulations used to treat and prevent iron deficiency including iron deficiency anemia.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Kupffer cell

Kupffer cells, also known as stellate macrophages and Kupffer-Browicz cells, are specialized macrophages located in the liver, lining the walls of the sinusoids.

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Legionella pneumophila

Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, nonspore-forming, Gram-negative bacterium of the genus Legionella.

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Legionnaires' disease

Legionnaires' disease is a form of atypical pneumonia caused by any type of Legionella bacteria.

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Leishmania

Leishmania is a genus of trypanosomes that are responsible for the disease leishmaniasis.

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Leishmaniasis

Leishmaniasis is a disease caused by parasites of the Leishmania type.

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Leukocyte extravasation

Leukocyte extravasation, less commonly called diapedesis, is the movement of leukocytes out of the circulatory system and towards the site of tissue damage or infection.

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Leydig cell

Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testicle.

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Lipopolysaccharide

Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Lymph node

A lymph node or lymph gland is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Lymphokine

Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte.

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Lysosome

A lysosome is a membrane-bound organelle found in nearly all animal cells.

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Lysozyme

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme produced by animals that forms part of the innate immune system.

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Macromolecule

A macromolecule is a very large molecule, such as protein, commonly created by the polymerization of smaller subunits (monomers).

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Macrophage colony-stimulating factor

The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types.

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Macrophage-1 antigen

Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2).

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Major histocompatibility complex

The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.

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Melanin

Melanin (from μέλας melas, "black, dark") is a broad term for a group of natural pigments found in most organisms.

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Melanocyte

Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.

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Microbiota

A microbiota is an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multicellular organisms studied to date from plants to animals.

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Microglia

Microglia are a type of neuroglia (glial cell) located throughout the brain and spinal cord.

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Microorganism

A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax. Microorganisms include all unicellular organisms and so are extremely diverse. Of the three domains of life identified by Carl Woese, all of the Archaea and Bacteria are microorganisms. These were previously grouped together in the two domain system as Prokaryotes, the other being the eukaryotes. The third domain Eukaryota includes all multicellular organisms and many unicellular protists and protozoans. Some protists are related to animals and some to green plants. Many of the multicellular organisms are microscopic, namely micro-animals, some fungi and some algae, but these are not discussed here. They live in almost every habitat from the poles to the equator, deserts, geysers, rocks and the deep sea. Some are adapted to extremes such as very hot or very cold conditions, others to high pressure and a few such as Deinococcus radiodurans to high radiation environments. Microorganisms also make up the microbiota found in and on all multicellular organisms. A December 2017 report stated that 3.45 billion year old Australian rocks once contained microorganisms, the earliest direct evidence of life on Earth. Microbes are important in human culture and health in many ways, serving to ferment foods, treat sewage, produce fuel, enzymes and other bioactive compounds. They are essential tools in biology as model organisms and have been put to use in biological warfare and bioterrorism. They are a vital component of fertile soils. In the human body microorganisms make up the human microbiota including the essential gut flora. They are the pathogens responsible for many infectious diseases and as such are the target of hygiene measures.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Monokine

A monokine is a type of cytokine produced primarily by monocytes and macrophages.

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Mononuclear phagocyte system

In immunology, the mononuclear phagocyte system or mononuclear phagocytic system (MPS) (also known as the reticuloendothelial system or macrophage system) is a part of the immune system that consists of the phagocytic cells located in reticular connective tissue.

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Mouse

A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.

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Mycobacterium tuberculosis

Mycobacterium tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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Necrosis

Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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NF-κB

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.

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Opsonin

An opsonin (from the Greek opsōneîn, to prepare for eating) is any molecule that enhances phagocytosis by marking an antigen for an immune response or marking dead cells for recycling (i.e., causes the phagocyte to "relish" the marked cell).

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Ornithine

Ornithine is a non-proteinogenic amino acid that plays a role in the urea cycle.

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Osteoclast

An osteoclast is a type of bone cell that breaks down bone tissue.

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Oxygen

Oxygen is a chemical element with symbol O and atomic number 8.

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Paracrine signalling

Paracrine signaling is a form of cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior of those cells.

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Parasitism

In evolutionary biology, parasitism is a relationship between species, where one organism, the parasite, lives on or in another organism, the host, causing it some harm, and is adapted structurally to this way of life.

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Pathogen

In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.

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Pathogen-associated molecular pattern

Pathogen-associated molecular patterns, or PAMPs, are molecules associated with groups of pathogens, that are recognized by cells of the innate immune system.

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Peritoneal cavity

The peritoneal cavity is a potential space between the parietal peritoneum (the peritoneum that surrounds the abdominal wall) and visceral peritoneum (the peritoneum that surrounds the internal organs).

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Peyer's patch

Peyer's patches (or aggregated lymphoid nodules, or occasionally PP for brevity) are organized lymphoid follicles, named after the 17th-century Swiss anatomist Johann Conrad Peyer.

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Phagocyte

Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.

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Phagocytosis

In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.

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Phagosome

In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

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Phi

Phi (uppercase Φ, lowercase φ or ϕ; ϕεῖ pheî; φι fi) is the 21st letter of the Greek alphabet.

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Pigment

A pigment is a material that changes the color of reflected or transmitted light as the result of wavelength-selective absorption.

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Placenta

The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, thermo-regulation, waste elimination, and gas exchange via the mother's blood supply; to fight against internal infection; and to produce hormones which support pregnancy.

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Pseudopodia

A pseudopod or pseudopodium (plural: pseudopods or pseudopodia) (from the Greek word ψευδοποδός, ψευδός "false" + ποδός "foot") is a temporary cytoplasm-filled projection of an eukaryotic cell membrane or a unicellular protist.

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Pulmonary alveolus

A pulmonary alveolus (plural: alveoli, from Latin alveolus, "little cavity") is a hollow cavity found in the lung parenchyma, and is the basic unit of ventilation.

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Radiation therapy

Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Red pulp

The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinuses that are engorged with blood, giving it a red color.

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Regeneration (biology)

In biology, regeneration is the process of renewal, restoration, and growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage.

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Regulatory macrophages

Regulatory macrophages (Mregs) represent one of basic macrophage population according fundamental macrophage function.

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Salamander

Salamanders are a group of amphibians typically characterized by a lizard-like appearance, with slender bodies, blunt snouts, short limbs projecting at right angles to the body, and the presence of a tail in both larvae and adults.

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Sinusoid (blood vessel)

A sinusoid is a small blood vessel that is a type of capillary similar to a fenestrated endothelium.

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Spleen

The spleen is an organ found in virtually all vertebrates.

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Surgery

Surgery (from the χειρουργική cheirourgikē (composed of χείρ, "hand", and ἔργον, "work"), via chirurgiae, meaning "hand work") is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas.

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Systemic inflammation

Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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T helper cell

The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.

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Targeted therapy

Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy.

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Tattoo

A tattoo is a form of body modification where a design is made by inserting ink, dyes and pigments, either indelible or temporary, into the dermis layer of the skin to change the pigment.

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Transforming growth factor beta

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.

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Trypan blue

Trypan blue is an azo dye that is used as a dye-stuff.

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Tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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Tumor necrosis factor superfamily

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers.

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Vascular endothelial growth factor

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Wound healing

Wound healing is an intricate process in which the skin repairs itself after injury.

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Activated macrophage, Angry macrophage, Chemotactic factors, macrophage, Clasmatocytes, Macrophages, Macrophagic, Macrophagous, Mphi, , , ΜΦ.

References

[1] https://en.wikipedia.org/wiki/Macrophage

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