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Metabolome

Index Metabolome

The metabolome refers to the complete set of small-molecule chemicals found within a biological sample. [1]

78 relations: Alkane, Amine, Amino acid, Antibiotic, Body fluid, Capillary electrophoresis, Cell (biology), Cerebrospinal fluid, Chemical shift, Chromatography, Chromosome, Cofactor (biochemistry), DNA, E. Coli Metabolome Database, Electron ionization, Electrospray ionization, Escherichia coli, Ester, Fatty acid, Food additive, Gas chromatography, Gas chromatography–mass spectrometry, Gel electrophoresis of proteins, Genome, Genotype, Glycolipid, Golm Metabolome Database, High-performance liquid chromatography, Human Metabolome Database, Inductively coupled plasma mass spectrometry, KEGG, Ketone, Lipid, Liquid chromatography–mass spectrometry, Macromolecule, Magnetic field, Mass spectrometry, Mass-to-charge ratio, Messenger RNA, Metabolite, Metabolomics, MetaCyc, MicroRNA, Molecular mass, Nuclear magnetic resonance, Nuclear magnetic resonance spectroscopy, Nucleic acid, Oligonucleotide, Organ (anatomy), Organelle, ..., Organic acid, Organism, Peptide, Phenotype, Pigment, Pollution, Polysaccharide, Primary metabolite, Protein, Protein sequencing, Proteome, Radio frequency, Ribosomal RNA, Saccharomyces cerevisiae, Secondary metabolite, Serum Metabolome Database, Small molecule, Sugar, Thiol, Tissue (biology), Toxin, Transcriptome, Tumor metabolome, University of Alberta, University of Calgary, Vitamin, Xenobiotic, Yeast Metabolome Database. Expand index (28 more) »

Alkane

In organic chemistry, an alkane, or paraffin (a historical name that also has other meanings), is an acyclic saturated hydrocarbon.

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Amine

In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

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Body fluid

Body fluid, bodily fluids, or biofluids are liquids within the bodies of living people.

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Capillary electrophoresis

Capillary electrophoresis (CE) is a family of electrokinetic separation methods performed in submillimeter diameter capillaries and in micro- and nanofluidic channels.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cerebrospinal fluid

Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.

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Chemical shift

In nuclear magnetic resonance (NMR) spectroscopy, the chemical shift is the resonant frequency of a nucleus relative to a standard in a magnetic field.

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Chromatography

Chromatography is a laboratory technique for the separation of a mixture.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Cofactor (biochemistry)

A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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E. Coli Metabolome Database

The E. coli Metabolome Database (ECMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in or produced by Escherichia coli (E. coli strain K12, MG1655).

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Electron ionization

Electron ionization (EI, formerly known as electron impact ionization and electron bombardment ionization) is an ionization method in which energetic electrons interact with solid or gas phase atoms or molecules to produce ions.

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Electrospray ionization

Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Ester

In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

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Fatty acid

In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.

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Food additive

Food additives are substances added to food to preserve flavor or enhance its taste, appearance, or other qualities.

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Gas chromatography

Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition.

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Gas chromatography–mass spectrometry

Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample.

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Gel electrophoresis of proteins

Protein electrophoresis is a method for analysing the proteins in a fluid or an extract.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Genotype

The genotype is the part of the genetic makeup of a cell, and therefore of an organism or individual, which determines one of its characteristics (phenotype).

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Glycolipid

Glycolipids are lipids with a carbohydrate attached by a glycosidic bond or covalently bonded.

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Golm Metabolome Database

The Golm Metabolome Database (GMD) is a gas chromatography (GC) – mass spectrometry (MS) reference library dedicated to metabolite profiling experiments and comprises mass spectral and retention index (RI) information for non-annotated mass spectral tags (MSTs, mass spectral information with retention time attached indices) together with data of a multitude of already identified metabolites and reference substances.

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High-performance liquid chromatography

High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture.

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Human Metabolome Database

The Human Metabolome Database (HMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in the human body.

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Inductively coupled plasma mass spectrometry

Inductively coupled plasma mass spectrometry (ICP-MS) is a type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.

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KEGG

KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.

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Ketone

In chemistry, a ketone (alkanone) is an organic compound with the structure RC(.

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Lipid

In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.

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Liquid chromatography–mass spectrometry

Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS).

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Macromolecule

A macromolecule is a very large molecule, such as protein, commonly created by the polymerization of smaller subunits (monomers).

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Magnetic field

A magnetic field is a vector field that describes the magnetic influence of electrical currents and magnetized materials.

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Mass spectrometry

Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio.

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Mass-to-charge ratio

The mass-to-charge ratio (m/Q) is a physical quantity that is most widely used in the electrodynamics of charged particles, e.g. in electron optics and ion optics.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Metabolomics

Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule intermediates and products of metabolism.

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MetaCyc

The MetaCyc database contains extensive information on metabolic pathways and enzymes from many organisms.

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MicroRNA

A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.

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Molecular mass

Relative Molecular mass or molecular weight is the mass of a molecule.

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Nuclear magnetic resonance

Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a magnetic field absorb and re-emit electromagnetic radiation.

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Nuclear magnetic resonance spectroscopy

Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei.

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Nucleic acid

Nucleic acids are biopolymers, or small biomolecules, essential to all known forms of life.

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Oligonucleotide

Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.

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Organ (anatomy)

Organs are collections of tissues with similar functions.

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Organelle

In cell biology, an organelle is a specialized subunit within a cell that has a specific function, in which their function is vital for the cell to live.

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Organic acid

An organic acid is an organic compound with acidic properties.

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Organism

In biology, an organism (from Greek: ὀργανισμός, organismos) is any individual entity that exhibits the properties of life.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Phenotype

A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).

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Pigment

A pigment is a material that changes the color of reflected or transmitted light as the result of wavelength-selective absorption.

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Pollution

Pollution is the introduction of contaminants into the natural environment that cause adverse change.

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Polysaccharide

Polysaccharides are polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic linkages, and on hydrolysis give the constituent monosaccharides or oligosaccharides.

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Primary metabolite

A primary metabolite is a kind of metabolite that is directly involved in normal growth, development, and reproduction.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein sequencing

Protein sequencing is the practical process of determining the amino acid sequence of all or part of a protein or peptide.

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Proteome

The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time.

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Radio frequency

Radio frequency (RF) refers to oscillatory change in voltage or current in a circuit, waveguide or transmission line in the range extending from around twenty thousand times per second to around three hundred billion times per second, roughly between the upper limit of audio and the lower limit of infrared.

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Ribosomal RNA

Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.

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Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast.

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Secondary metabolite

Secondary metabolites are organic compounds that are not directly involved in the normal growth, development, or reproduction of an organism.

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Serum Metabolome Database

The Serum Metabolome database is a free web database about small molecule metabolites found in human serum and their concentration values.

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Small molecule

Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight (< 900 daltons) organic compound that may regulate a biological process, with a size on the order of 1 nm.

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Sugar

Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food.

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Thiol

Thiol is an organosulfur compound that contains a carbon-bonded sulfhydryl (R–SH) group (where R represents an alkyl or other organic substituent).

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Toxin

A toxin (from toxikon) is a poisonous substance produced within living cells or organisms; synthetic toxicants created by artificial processes are thus excluded.

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Transcriptome

The transcriptome is the set of all RNA molecules in one cell or a population of cells.

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Tumor metabolome

The study of the tumor metabolism, also known as tumor metabolome describes the different characteristic metabolic changes in tumor cells.

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University of Alberta

The University of Alberta (also known as U of A and UAlberta) is a public research university located in Edmonton, Alberta, Canada.

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University of Calgary

The University of Calgary (U of C or UCalgary) is a public research university located in Calgary, Alberta, Canada.

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Vitamin

A vitamin is an organic molecule (or related set of molecules) which is an essential micronutrient - that is, a substance which an organism needs in small quantities for the proper functioning of its metabolism - but cannot synthesize it (either at all, or in sufficient quantities), and therefore it must be obtained through the diet.

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Xenobiotic

A xenobiotic is a chemical substance found within an organism that is not naturally produced or expected to be present within the organism.

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Yeast Metabolome Database

The Yeast Metabolome Database (YMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in or produced by Saccharomyces cerevisiae (Baker’s yeast).

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References

[1] https://en.wikipedia.org/wiki/Metabolome

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