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Discovery and development of cyclooxygenase 2 inhibitors and Nonsteroidal anti-inflammatory drug

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Discovery and development of cyclooxygenase 2 inhibitors and Nonsteroidal anti-inflammatory drug

Discovery and development of cyclooxygenase 2 inhibitors vs. Nonsteroidal anti-inflammatory drug

Cyclooxygenases are enzymes that take part in a complex biosynthetic cascade that results in the conversion of polyunsaturated fatty acids to prostaglandins and thromboxane(s). Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.

Similarities between Discovery and development of cyclooxygenase 2 inhibitors and Nonsteroidal anti-inflammatory drug

Discovery and development of cyclooxygenase 2 inhibitors and Nonsteroidal anti-inflammatory drug have 23 things in common (in Unionpedia): Analgesic, Arachidonic acid, Celecoxib, COX-2 inhibitor, COX-3, Cyclooxygenase, Enzyme inhibitor, Etoricoxib, Gastrointestinal tract, Hydrolysis, Indometacin, Lumiracoxib, Myocardial infarction, Naproxen, Osteoarthritis, Parecoxib, Prostaglandin, Prostaglandin-endoperoxide synthase 2, Prostanoid, PTGS1, Rofecoxib, Thromboxane, Valdecoxib.

Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

Analgesic and Discovery and development of cyclooxygenase 2 inhibitors · Analgesic and Nonsteroidal anti-inflammatory drug · See more »

Arachidonic acid

Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).

Arachidonic acid and Discovery and development of cyclooxygenase 2 inhibitors · Arachidonic acid and Nonsteroidal anti-inflammatory drug · See more »

Celecoxib

Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).

Celecoxib and Discovery and development of cyclooxygenase 2 inhibitors · Celecoxib and Nonsteroidal anti-inflammatory drug · See more »

COX-2 inhibitor

Selective COX-2 inhibitors are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly targets cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain.

COX-2 inhibitor and Discovery and development of cyclooxygenase 2 inhibitors · COX-2 inhibitor and Nonsteroidal anti-inflammatory drug · See more »

COX-3

COX-3 is an enzyme that is encoded by the PTGS1 (COX1) gene, but is not functional in humans.

COX-3 and Discovery and development of cyclooxygenase 2 inhibitors · COX-3 and Nonsteroidal anti-inflammatory drug · See more »

Cyclooxygenase

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid.

Cyclooxygenase and Discovery and development of cyclooxygenase 2 inhibitors · Cyclooxygenase and Nonsteroidal anti-inflammatory drug · See more »

Enzyme inhibitor

4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.

Discovery and development of cyclooxygenase 2 inhibitors and Enzyme inhibitor · Enzyme inhibitor and Nonsteroidal anti-inflammatory drug · See more »

Etoricoxib

Etoricoxib (Arcoxia) is a selective COX-2 inhibitor from Merck & Co. Currently it is approved in more than 80 countries worldwide but not in the US, where the Food and Drug Administration (FDA) has required additional safety and efficacy data for etoricoxib before it will issue approval.

Discovery and development of cyclooxygenase 2 inhibitors and Etoricoxib · Etoricoxib and Nonsteroidal anti-inflammatory drug · See more »

Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

Discovery and development of cyclooxygenase 2 inhibitors and Gastrointestinal tract · Gastrointestinal tract and Nonsteroidal anti-inflammatory drug · See more »

Hydrolysis

Hydrolysis is a term used for both an electro-chemical process and a biological one.

Discovery and development of cyclooxygenase 2 inhibitors and Hydrolysis · Hydrolysis and Nonsteroidal anti-inflammatory drug · See more »

Indometacin

Indometacin (INN; or USAN indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation.

Discovery and development of cyclooxygenase 2 inhibitors and Indometacin · Indometacin and Nonsteroidal anti-inflammatory drug · See more »

Lumiracoxib

Lumiracoxib (rINN) is a carboxylic acid COX-2 selective inhibitor nonsteroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige (sometimes misquoted as "Prestige" by the media).

Discovery and development of cyclooxygenase 2 inhibitors and Lumiracoxib · Lumiracoxib and Nonsteroidal anti-inflammatory drug · See more »

Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

Discovery and development of cyclooxygenase 2 inhibitors and Myocardial infarction · Myocardial infarction and Nonsteroidal anti-inflammatory drug · See more »

Naproxen

Naproxen (brand names: Aleve, Naprosyn, and many others) is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness.

Discovery and development of cyclooxygenase 2 inhibitors and Naproxen · Naproxen and Nonsteroidal anti-inflammatory drug · See more »

Osteoarthritis

Osteoarthritis (OA) is a type of joint disease that results from breakdown of joint cartilage and underlying bone.

Discovery and development of cyclooxygenase 2 inhibitors and Osteoarthritis · Nonsteroidal anti-inflammatory drug and Osteoarthritis · See more »

Parecoxib

Parecoxib is a water-soluble and injectable prodrug of valdecoxib.

Discovery and development of cyclooxygenase 2 inhibitors and Parecoxib · Nonsteroidal anti-inflammatory drug and Parecoxib · See more »

Prostaglandin

The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.

Discovery and development of cyclooxygenase 2 inhibitors and Prostaglandin · Nonsteroidal anti-inflammatory drug and Prostaglandin · See more »

Prostaglandin-endoperoxide synthase 2

Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (The HUGO official symbol is PTGS2; HGNC ID, HGNC:9605), also known as cyclooxygenase-2 or COX-2, is an enzyme that in humans is encoded by the PTGS2 gene.

Discovery and development of cyclooxygenase 2 inhibitors and Prostaglandin-endoperoxide synthase 2 · Nonsteroidal anti-inflammatory drug and Prostaglandin-endoperoxide synthase 2 · See more »

Prostanoid

Prostanoids are a subclass of eicosanoids consisting of the prostaglandins (mediators of inflammatory and anaphylactic reactions), the thromboxanes (mediators of vasoconstriction), and the prostacyclins (active in the resolution phase of inflammation.).

Discovery and development of cyclooxygenase 2 inhibitors and Prostanoid · Nonsteroidal anti-inflammatory drug and Prostanoid · See more »

PTGS1

Cyclooxygenase 1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene.

Discovery and development of cyclooxygenase 2 inhibitors and PTGS1 · Nonsteroidal anti-inflammatory drug and PTGS1 · See more »

Rofecoxib

Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that has now been withdrawn over safety concerns.

Discovery and development of cyclooxygenase 2 inhibitors and Rofecoxib · Nonsteroidal anti-inflammatory drug and Rofecoxib · See more »

Thromboxane

Thromboxane is a member of the family of lipids known as eicosanoids.

Discovery and development of cyclooxygenase 2 inhibitors and Thromboxane · Nonsteroidal anti-inflammatory drug and Thromboxane · See more »

Valdecoxib

Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms.

Discovery and development of cyclooxygenase 2 inhibitors and Valdecoxib · Nonsteroidal anti-inflammatory drug and Valdecoxib · See more »

The list above answers the following questions

Discovery and development of cyclooxygenase 2 inhibitors and Nonsteroidal anti-inflammatory drug Comparison

Discovery and development of cyclooxygenase 2 inhibitors has 91 relations, while Nonsteroidal anti-inflammatory drug has 251. As they have in common 23, the Jaccard index is 6.73% = 23 / (91 + 251).

References

This article shows the relationship between Discovery and development of cyclooxygenase 2 inhibitors and Nonsteroidal anti-inflammatory drug. To access each article from which the information was extracted, please visit:

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