Faster access than browser!Similarities between Nonsteroidal anti-inflammatory drug and Opioid
Nonsteroidal anti-inflammatory drug and Opioid have 20 things in common (in Unionpedia): Analgesic, Aspirin, Biological half-life, Central nervous system, Diarrhea, Dizziness, Gastrointestinal tract, Headache, Hives, Hypothalamus, Ibuprofen, Irritable bowel syndrome, Menstruation, Migraine, Naproxen, Over-the-counter drug, Pain, Paracetamol, Placebo, Rheumatoid arthritis.
Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
Analgesic and Nonsteroidal anti-inflammatory drug · Analgesic and Opioid ·
Aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a medication used to treat pain, fever, or inflammation.
Aspirin and Nonsteroidal anti-inflammatory drug · Aspirin and Opioid ·
Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
Biological half-life and Nonsteroidal anti-inflammatory drug · Biological half-life and Opioid ·
Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
Central nervous system and Nonsteroidal anti-inflammatory drug · Central nervous system and Opioid ·
Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
Diarrhea and Nonsteroidal anti-inflammatory drug · Diarrhea and Opioid ·
Dizziness
Dizziness is an impairment in spatial perception and stability.
Dizziness and Nonsteroidal anti-inflammatory drug · Dizziness and Opioid ·
Gastrointestinal tract
The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.
Gastrointestinal tract and Nonsteroidal anti-inflammatory drug · Gastrointestinal tract and Opioid ·
Headache
Headache is the symptom of pain anywhere in the region of the head or neck.
Headache and Nonsteroidal anti-inflammatory drug · Headache and Opioid ·
Hives
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.
Hives and Nonsteroidal anti-inflammatory drug · Hives and Opioid ·
Hypothalamus
The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.
Hypothalamus and Nonsteroidal anti-inflammatory drug · Hypothalamus and Opioid ·
Ibuprofen
Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.
Ibuprofen and Nonsteroidal anti-inflammatory drug · Ibuprofen and Opioid ·
Irritable bowel syndrome
Irritable bowel syndrome (IBS) is a group of symptoms—including abdominal pain and changes in the pattern of bowel movements without any evidence of underlying damage.
Irritable bowel syndrome and Nonsteroidal anti-inflammatory drug · Irritable bowel syndrome and Opioid ·
Menstruation
Menstruation, also known as a period or monthly, is the regular discharge of blood and mucosal tissue (known as menses) from the inner lining of the uterus through the vagina.
Menstruation and Nonsteroidal anti-inflammatory drug · Menstruation and Opioid ·
Migraine
A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe.
Migraine and Nonsteroidal anti-inflammatory drug · Migraine and Opioid ·
Naproxen
Naproxen (brand names: Aleve, Naprosyn, and many others) is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness.
Naproxen and Nonsteroidal anti-inflammatory drug · Naproxen and Opioid ·
Over-the-counter drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a prescription from a healthcare professional, as opposed to prescription drugs, which may be sold only to consumers possessing a valid prescription.
Nonsteroidal anti-inflammatory drug and Over-the-counter drug · Opioid and Over-the-counter drug ·
Pain
Pain is a distressing feeling often caused by intense or damaging stimuli.
Nonsteroidal anti-inflammatory drug and Pain · Opioid and Pain ·
Paracetamol
--> Acetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of Antifebrin by A. Cahn and P. Hepp in 1886. But its unacceptable toxic effects, the most alarming being cyanosis due to methemoglobinemia, prompted the search for less toxic aniline derivatives. Harmon Northrop Morse had already synthesised paracetamol at Johns Hopkins University via the reduction of ''p''-nitrophenol with tin in glacial acetic acid in 1877, but it was not until 1887 that clinical pharmacologist Joseph von Mering tried paracetamol on humans. In 1893, von Mering published a paper reporting on the clinical results of paracetamol with phenacetin, another aniline derivative. Von Mering claimed that, unlike phenacetin, paracetamol had a slight tendency to produce methemoglobinemia. Paracetamol was then quickly discarded in favor of phenacetin. The sales of phenacetin established Bayer as a leading pharmaceutical company. Overshadowed in part by aspirin, introduced into medicine by Heinrich Dreser in 1899, phenacetin was popular for many decades, particularly in widely advertised over-the-counter "headache mixtures", usually containing phenacetin, an aminopyrine derivative of aspirin, caffeine, and sometimes a barbiturate. Paracetamol is the active metabolite of phenacetin and acetanilide, both once popular as analgesics and antipyretics in their own right. However, unlike phenacetin, acetanilide and their combinations, paracetamol is not considered carcinogenic at therapeutic doses. Von Mering's claims remained essentially unchallenged for half a century, until two teams of researchers from the United States analyzed the metabolism of acetanilide and paracetamol. In 1947 David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in human blood, and in a subsequent study they reported that large doses of paracetamol given to albino rats did not cause methemoglobinemia. In three papers published in the September 1948 issue of the Journal of Pharmacology and Experimental Therapeutics, Bernard Brodie, Julius Axelrod and Frederick Flinn confirmed using more specific methods that paracetamol was the major metabolite of acetanilide in human blood, and established that it was just as efficacious an analgesic as its precursor. They also suggested that methemoglobinemia is produced in humans mainly by another metabolite, phenylhydroxylamine. A follow-up paper by Brodie and Axelrod in 1949 established that phenacetin was also metabolised to paracetamol. This led to a "rediscovery" of paracetamol. It has been suggested that contamination of paracetamol with 4-aminophenol, the substance von Mering synthesised it from, may be the cause for his spurious findings. Paracetamol was first marketed in the United States in 1950 under the name Triagesic, a combination of paracetamol, aspirin, and caffeine. Reports in 1951 of three users stricken with the blood disease agranulocytosis led to its removal from the marketplace, and it took several years until it became clear that the disease was unconnected. Paracetamol was marketed in 1953 by Sterling-Winthrop Co. as Panadol, available only by prescription, and promoted as preferable to aspirin since it was safe for children and people with ulcers. In 1955, paracetamol was marketed as Children's Tylenol Elixir by McNeil Laboratories. In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol, produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents. Concerns about paracetamol's safety delayed its widespread acceptance until the 1970s, but in the 1980s paracetamol sales exceeded those of aspirin in many countries, including the United Kingdom. This was accompanied by the commercial demise of phenacetin, blamed as the cause of analgesic nephropathy and hematological toxicity. In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the over the counter drug rights to SmithKline Beecham in 1994. Available without a prescription since 1959, it has since become a common household drug. Patents on paracetamol have long expired, and generic versions of the drug are widely available.
Nonsteroidal anti-inflammatory drug and Paracetamol · Opioid and Paracetamol ·
Placebo
A placebo is a substance or treatment of no intended therapeutic value.
Nonsteroidal anti-inflammatory drug and Placebo · Opioid and Placebo ·
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
Nonsteroidal anti-inflammatory drug and Rheumatoid arthritis · Opioid and Rheumatoid arthritis ·
The list above answers the following questions
- What Nonsteroidal anti-inflammatory drug and Opioid have in common
- What are the similarities between Nonsteroidal anti-inflammatory drug and Opioid
Nonsteroidal anti-inflammatory drug and Opioid Comparison
Nonsteroidal anti-inflammatory drug has 251 relations, while Opioid has 542. As they have in common 20, the Jaccard index is 2.52% = 20 / (251 + 542).
References
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