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Norgestimate

Index Norgestimate

Norgestimate, sold under the brand names Ortho Tri-Cyclen and Previfem among others, is a progestin medication which is used in birth control pills for women and in menopausal hormone therapy. [1]

140 relations: Abdominal pain, Acetate, Acetyl group, Acetylation, Active metabolite, Agonist, Aldosterone, Androgen, Androgen receptor, Antiandrogen, Antigonadotropin, Antimineralocorticoid, Anxiety, Area under the curve (pharmacokinetics), Arthralgia, Asia, Australia, Back pain, Biofilm, Biological activity, Biological half-life, Biological target, Biotransformation, Blood proteins, Brazil, Breast disease, Breast enlargement, Breast pain, Canada, China, Cis–trans isomerism, Clinical trial, Cmax (pharmacology), Combined oral contraceptive pill, Cough, Cytochrome P450, Depression (mood), Derivative (chemistry), Dihydrotestosterone, Dizziness, Dysmenorrhea, Elimination (pharmacology), Enzyme, Enzyme inhibitor, Ester, Estradiol (medication), Estrane, Estrogen (medication), Ethinylestradiol, Europe, ..., Fatigue, Feces, First pass effect, Flatulence, Gastrointestinal tract, Generic drug, Gestodene, Glucocorticoid, Gonane, Headache, Hormonal contraception, Hormone, Human serum albumin, Hydrocortisone, Hydroxylation, Hyperandrogenism, In vitro, India, Influenza-like illness, Ireland, Irregular menstruation, Japan, Latin America, Lead compound, Levonorgestrel, Levonorgestrel acetate, Ligand (biochemistry), Liver, Menopause, Menstrual cycle, Metabolism, Metabolite, Methicillin, Metribolone, Migraine, Mood (psychology), Mood disorder, Myalgia, Nandrolone, Nausea, Neurosteroid, New Zealand, Nipple discharge, Norelgestromin, Norethisterone, Norethisterone acetate oxime, Off-target activity, Oral administration, Organic compound, Oxime, Pain, Pharmacokinetics, Pharyngitis, Plasma protein binding, Postmenopausal hormone therapy, Prodrug, Progesterone, Progesterone (medication), Progesterone receptor, Progestin, Progestogen, Progestogen ester, Promegestone, Prostate, Racemic mixture, Rash, Redox, Sex hormone-binding globulin, Side effect, Sinusitis, South Africa, South Korea, Staphylococcus, Staphylococcus aureus, Steroid, Steroid hormone receptor, Symptom, Testosterone, Testosterone (medication), Tooth pathology, Trademark distinctiveness, United Kingdom, United States, Upper respiratory tract infection, Urine, Vaginal bleeding, Vaginal discharge, Vaginitis, Viral disease, 5α-Reductase. Expand index (90 more) »

Abdominal pain

Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues.

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Acetate

An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.

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Acetyl group

In organic chemistry, acetyl is a moiety, the acyl with chemical formula CH3CO.

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Acetylation

Acetylation (or in IUPAC nomenclature ethanoylation) describes a reaction that introduces an acetyl functional group into a chemical compound.

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Active metabolite

An active metabolite is an active form of a drug after it has been processed by the body.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Aldosterone

Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Antiandrogen

Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.

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Antigonadotropin

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

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Antimineralocorticoid

An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.

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Anxiety

Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.

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Area under the curve (pharmacokinetics)

In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral in a plot of drug concentration in blood plasma vs.

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Arthralgia

Arthralgia (from Greek arthro-, joint + -algos, pain) literally means joint pain; it is a symptom of injury, infection, illnesses (in particular arthritis) or an allergic reaction to medication.

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Asia

Asia is Earth's largest and most populous continent, located primarily in the Eastern and Northern Hemispheres.

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Australia

Australia, officially the Commonwealth of Australia, is a sovereign country comprising the mainland of the Australian continent, the island of Tasmania and numerous smaller islands.

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Back pain

Back pain is pain felt in the back of the body.

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Biofilm

A biofilm comprises any group of microorganisms in which cells stick to each other and often also to a surface.

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Biological activity

In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.

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Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Biotransformation

Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound.

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Blood proteins

Blood proteins, also termed plasma proteins, are proteins present in blood plasma.

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Brazil

Brazil (Brasil), officially the Federative Republic of Brazil (República Federativa do Brasil), is the largest country in both South America and Latin America.

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Breast disease

Breast diseases can be classified either with disorders of the integument, or disorders of the reproductive system.

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Breast enlargement

Breast enlargement is the enlargement of the breasts.

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Breast pain

Breast pain is a medical symptom that is most often associated with a developing disease or condition of the breast.

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Canada

Canada is a country located in the northern part of North America.

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China

China, officially the People's Republic of China (PRC), is a unitary one-party sovereign state in East Asia and the world's most populous country, with a population of around /1e9 round 3 billion.

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Cis–trans isomerism

Cis–trans isomerism, also known as geometric isomerism or configurational isomerism, is a term used in organic chemistry.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Cmax (pharmacology)

Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.

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Combined oral contraceptive pill

The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women.

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Cough

A cough is a sudden and often repetitively occurring, protective reflex, which helps to clear the large breathing passages from fluids, irritants, foreign particles and microbes.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Depression (mood)

Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Dihydrotestosterone

Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.

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Dizziness

Dizziness is an impairment in spatial perception and stability.

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Dysmenorrhea

Dysmenorrhea, also known as painful periods, or menstrual cramps, is pain during menstruation.

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Elimination (pharmacology)

In pharmacology the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Enzyme inhibitor

4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.

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Ester

In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

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Estradiol (medication)

Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.

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Estrane

Estrane is a C18 steroid derivative, with a gonane core.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Ethinylestradiol

Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins.

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Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

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Fatigue

Fatigue is a subjective feeling of tiredness that has a gradual onset.

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Feces

Feces (or faeces) are the solid or semisolid remains of the food that could not be digested in the small intestine.

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First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation.

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Flatulence

Flatulence is defined in the medical literature as "flatus expelled through the anus" or the "quality or state of being flatulent", which is defined in turn as "marked by or affected with gases generated in the intestine or stomach; likely to cause digestive flatulence".

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Generic drug

A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.

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Gestodene

Gestodene, sold under the brand names Femodene and Minulet among others, is a progestin medication which is used in birth control pills for women.

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Glucocorticoid

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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Gonane

Gonane (C17), also known as perhydrocyclopentaphenanthrene, is a tetracyclic hydrocarbon ring structure and the fundamental steroid nucleus.

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Headache

Headache is the symptom of pain anywhere in the region of the head or neck.

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Hormonal contraception

Hormonal contraception refers to birth control methods that act on the endocrine system.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Human serum albumin

Human serum albumin is the serum albumin found in human blood.

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Hydrocortisone

Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hydroxylation

Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.

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Hyperandrogenism

Hyperandrogenism, also known as androgen excess, is a medical condition characterized by excessive levels of androgens (male sex hormones such as testosterone) in the female body and the associated effects of the elevated androgen levels.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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India

India (IAST), also called the Republic of India (IAST), is a country in South Asia.

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Influenza-like illness

Influenza-like illness (ILI), also known as acute respiratory infection (ARI) and flu-like syndrome/symptoms, is a medical diagnosis of possible influenza or other illness causing a set of common symptoms.

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Ireland

Ireland (Éire; Ulster-Scots: Airlann) is an island in the North Atlantic.

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Irregular menstruation

Irregular menstruation is a menstrual disorder whose manifestations include irregular cycle lengths as well as metrorrhagia (vaginal bleeding between expected periods).

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Japan

Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.

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Latin America

Latin America is a group of countries and dependencies in the Western Hemisphere where Spanish, French and Portuguese are spoken; it is broader than the terms Ibero-America or Hispanic America.

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Lead compound

A lead compound (i.e. a "leading" compound, not to be confused with various compounds of the metallic element lead) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may nevertheless have suboptimal structure that requires modification to fit better to the target; lead drugs offer the prospect of being followed by back-up compounds.

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Levonorgestrel

Levonorgestrel is a hormonal medication which is used in a number of birth control methods.

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Levonorgestrel acetate

Levonorgestrel acetate (LNG-A), or levonorgestrel 17β-acetate, also known as 3-ketonorgestimate, is a progestin which was never marketed.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Menopause

Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.

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Menstrual cycle

The menstrual cycle is the regular natural change that occurs in the female reproductive system (specifically the uterus and ovaries) that makes pregnancy possible.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Methicillin

Methicillin, also known as meticillin, is a narrow-spectrum β-lactam antibiotic of the penicillin class.

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Metribolone

Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.

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Migraine

A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe.

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Mood (psychology)

In psychology, a mood is an emotional state.

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Mood disorder

Mood disorder, also known as mood (affective) disorders, is a group of conditions where a disturbance in the person's mood is the main underlying feature.

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Myalgia

Myalgia, or muscle pain, is a symptom of many diseases and disorders.

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Nandrolone

Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).

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Nausea

Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.

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Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.

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New Zealand

New Zealand (Aotearoa) is a sovereign island country in the southwestern Pacific Ocean.

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Nipple discharge

Nipple discharge is the release of fluid from the nipples of the breasts.

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Norelgestromin

Norelgestromin, or norelgestromine, sold under the brand names Evra and Ortho Evra among others, is a progestin medication which is used as a method of birth control for women.

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Norethisterone

Norethisterone, also known as norethindrone and sold under the brand names Aygestin and Primolut N among many others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.

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Norethisterone acetate oxime

Norethisterone acetate oxime (developmental code names ORF-5263, So-36), or norethindrone acetate oxime, is a steroidal progestin of the 19-nortestosterone group which was developed as a postcoital contraceptive but was never marketed.

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Off-target activity

Off-target activity is biological activity of a drug that is different from and not at that of its intended biological target.

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Oral administration

| name.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Oxime

An oxime is a chemical compound belonging to the imines, with the general formula R1R2C.

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Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

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Pharyngitis

Pharyngitis is inflammation of the back of the throat, known as the pharynx.

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Plasma protein binding

Plasma protein binding refers to the degree to which medications attach to proteins within the blood.

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Postmenopausal hormone therapy

Menopausal hormone therapy (MHT), or postmenopausal hormone therapy (PHT, PMHT), also known as hormone replacement therapy in menopause, is a form of hormone replacement therapy (HRT) which is used in postmenopausal, perimenopausal, and surgically menopausal women.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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Progesterone (medication)

Progesterone is a medication and naturally occurring steroid hormone.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Progestin

A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Progestogen

Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).

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Progestogen ester

A progestogen ester is an ester of a progestogen or progestin (a synthetic progestogen).

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Promegestone

Promegestone, sold under the brand name Surgestone, is a progestin medication which is used in menopausal hormone therapy and in the treatment of gynecological disorders.

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Prostate

The prostate (from Ancient Greek προστάτης, prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.

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Racemic mixture

In chemistry, a racemic mixture, or racemate, is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule.

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Rash

A rash is a change of the human skin which affects its color, appearance, or texture.

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Redox

Redox (short for reduction–oxidation reaction) (pronunciation: or) is a chemical reaction in which the oxidation states of atoms are changed.

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Sex hormone-binding globulin

Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen.

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Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

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Sinusitis

Sinusitis, also known as a sinus infection or rhinosinusitis, is inflammation of the sinuses resulting in symptoms.

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South Africa

South Africa, officially the Republic of South Africa (RSA), is the southernmost country in Africa.

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South Korea

South Korea, officially the Republic of Korea (대한민국; Hanja: 大韓民國; Daehan Minguk,; lit. "The Great Country of the Han People"), is a country in East Asia, constituting the southern part of the Korean Peninsula and lying east to the Asian mainland.

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Staphylococcus

Staphylococcus (from the σταφυλή, staphylē, "grape" and κόκκος, kókkos, "granule") is a genus of Gram-positive bacteria.

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Staphylococcus aureus

Staphylococcus aureus is a Gram-positive, round-shaped bacterium that is a member of the Firmicutes, and it is a member of the normal flora of the body, frequently found in the nose, respiratory tract, and on the skin.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Steroid hormone receptor

Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.

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Symptom

A symptom (from Greek σύμπτωμα, "accident, misfortune, that which befalls", from συμπίπτω, "I befall", from συν- "together, with" and πίπτω, "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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Testosterone (medication)

Testosterone is a medication and naturally occurring steroid hormone.

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Tooth pathology

Tooth pathology (or tooth diseases, tooth disorders or dental pathology), is any condition of the teeth that can be congenital or acquired.

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Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

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United Kingdom

The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain,Usage is mixed with some organisations, including the and preferring to use Britain as shorthand for Great Britain is a sovereign country in western Europe.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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Upper respiratory tract infection

Upper respiratory tract infections (URTI) are illnesses caused by an acute infection which involves the upper respiratory tract including the nose, sinuses, pharynx or larynx.

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Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

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Vaginal bleeding

Vaginal bleeding is any bleeding through the vagina, including bleeding from the vaginal wall itself, as well as (and more commonly) bleeding from another location of the female reproductive system, often the uterus.

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Vaginal discharge

Vaginal discharge is a mixture of liquid, cells, and bacteria that lubricates and protects the vagina.

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Vaginitis

Vaginitis is inflammation of the vagina.

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Viral disease

A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells.

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5α-Reductase

5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.

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Redirects here:

Ortho Cyclen-21, Ortho Cyclen-28, Ortho-Prefest, Prefest.

References

[1] https://en.wikipedia.org/wiki/Norgestimate

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