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27 relations: Amino acid, Cell (journal), Cell nucleus, Chaperone (protein), DNA, Eukaryote, GTPase, GTPase-activating protein, Guanine nucleotide exchange factor, Hydrolysis, Importin, Importin α, Journal of Cell Biology, Karyopherin, Nature Structural & Molecular Biology, Nuclear export signal, Nuclear pore, Nuclear transport, Proline, Ran (protein), RNA, Structure (journal), SV40 large T antigen, Transportin 1, Trends (journals), Tyrosine, Xenopus.
Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Cell (journal)
Cell is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Chaperone (protein)
In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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GTPase
GTPases (singular GTPase) are a large family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP).
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GTPase-activating protein
GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event.
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Guanine nucleotide exchange factor
Guanine nucleotide exchange factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP).
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Hydrolysis
Hydrolysis is a term used for both an electro-chemical process and a biological one.
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Importin
Importin is a type of karyopherin that transports protein molecules into the nucleus by binding to specific recognition sequences, called nuclear localization sequences (NLS).
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Importin α
Importin alpha, or karyopherin alpha refers to a class of adaptor proteins that are involved in the import of proteins into the cell nucleus.
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Journal of Cell Biology
Journal of Cell Biology is an international, peer-reviewed journal owned by The Rockefeller University and published by Rockefeller University Press.
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Karyopherin
Karyopherins are a group of proteins involved in transporting molecules between the cytoplasm and the nucleus of a eukaryotic cell.
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Nature Structural & Molecular Biology
Nature Structural & Molecular Biology is a monthly peer-reviewed scientific journal publishing research articles, reviews, news, and commentaries in structural and molecular biology, with an emphasis on papers that further a "functional and mechanistic understanding of how molecular components in a biological process work together".
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Nuclear export signal
A nuclear export signal (NES) is a short amino acid sequence of 4 hydrophobic residues in a protein that targets it for export from the cell nucleus to the cytoplasm through the nuclear pore complex using nuclear transport.
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Nuclear pore
Nuclear pore complexes are large protein complexes that span the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus.
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Nuclear transport
The entry and exit of large molecules from the cell nucleus is tightly controlled by the nuclear pore complexes (NPCs).
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Proline
Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.
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Ran (protein)
Ran (RAs-related Nuclear protein) also known as GTP-binding nuclear protein Ran is a protein that in humans is encoded by the RAN gene.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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Structure (journal)
Structure is a peer-reviewed scientific journal founded by Wayne Hendrickson, Carl-Ivar Brändén and Alan R. Fersht in September 1993.
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SV40 large T antigen
SV40 large T antigen (Simian Vacuolating Virus 40 TAg) is a hexamer protein that is a dominant-acting oncoprotein derived from the polyomavirus SV40.
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Transportin 1
Transportin-1 (or Importin-β 2) is a protein that in humans is encoded by the TNPO1 gene.
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Trends (journals)
Trends is a series of scientific journals owned by Elsevier that publish review articles in a range of areas of biology.
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Tyrosine
Tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.
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Xenopus
Xenopus (Gk., ξενος, xenos.
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References
[1] https://en.wikipedia.org/wiki/Nuclear_localization_sequence
