Rejuvenation (aging) and Senescence

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Difference between Rejuvenation (aging) and Senescence

Rejuvenation (aging) vs. Senescence

Rejuvenation is a medical discipline focused on the practical reversal of the aging process. Senescence or biological ageing is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation.

Ageing

Ageing or aging (see spelling differences) is the process of becoming older.

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Aging brain

Aging is a major risk factor for most common neurodegenerative diseases, including mild cognitive impairment, dementias including Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease.

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Biological immortality

Biological immortality (sometimes referred to bio-indefinite mortality) is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell division

Cell division is the process by which a parent cell divides into two or more daughter cells.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Cross-link

A cross-link is a bond that links one polymer chain to another.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA damage theory of aging

The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages.

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DNA repair

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Gene therapy

In the medicine field, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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Gerontology

Gerontology is the study of the social, cultural, psychological, cognitive, and biological aspects of ageing.

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Hayflick limit

The Hayflick limit or Hayflick phenomenon is the number of times a normal human cell population will divide before cell division stops.

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Homologous recombination

Homologous recombination is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA.

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Immortality

Immortality is eternal life, being exempt from death, unending existence.

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Indefinite lifespan

Indefinite lifespan (also known as indefinite life extension or bio-indefinite) is a term used in the life extension movement and transhumanism to refer to the hypothetical longevity of humans (and other life-forms) under conditions in which ageing is effectively and completely prevented and treated.

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Life extension

Life extension science, also known as anti-aging medicine, indefinite life extension, experimental gerontology, and biomedical gerontology, is the study of slowing down or reversing the processes of aging to extend both the maximum and average lifespan.

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Lipofuscin

Lipofuscin is the name given to fine yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion.

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Maximum life span

Maximum life span (or, for humans, maximum reported age at death) is a measure of the maximum amount of time one or more members of a population have been observed to survive between birth and death.

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Mitochondrion

The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Nature (journal)

Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Radical (chemistry)

In chemistry, a radical (more precisely, a free radical) is an atom, molecule, or ion that has an unpaired valence electron.

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Regenerative medicine

Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the "process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function".

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SAGE KE

The Science of Aging Knowledge Environment (SAGE KE) was an online scientific resource provided by the American Association for the Advancement of Science (AAAS).

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Stem cell

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

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Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres.

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Telomere

A telomere is a region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes.

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Timeline of senescence research

This page is a timeline of senescence research, including major theories, breakthroughs and organizations.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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