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Activator (genetics)

Index Activator (genetics)

A transcriptional activator is a protein (transcription factor) that increases gene transcription of a gene or set of genes. [1]

106 relations: Activator, Ada regulon, AFF3, Aliivibrio fischeri, AP-1 transcription factor, APC/C activator protein CDH1, Arc system, ARID2, ASPSCR1, B-Cell Prolymphocytic Leukemia, Bacillus anthracis, BEND2 (protein), BESS domain, Bimolecular fluorescence complementation, Bioreporter, Cas9, Catabolite activator protein, CII protein, CIITA, CLOCK, Coactivator (genetics), Cryptochrome, DCas9 activation system, Distal promoter, Ebola virus, Effector (biology), ELK1, Enhancer (genetics), Estrogen receptor alpha, ETS transcription factor family, Feedback, FNR regulon, FOXM1, G-less cassette, GAL4/UAS system, GATA1, Gene, Gene expression, Gene structure, General transcription factor, GLI2, GlnALG operon, Glossary of gene expression terms, Hedgehog signaling pathway, Histone acetylation and deacetylation, Histone acetyltransferase, HIV, Inducer, Internal control region, Jeffrey L. Price, ..., Jun dimerization protein, Kruppel-like factors, L-arabinose operon, Lac operon, LacUV5, LuxR-type DNA-binding HTH domain, Maize, MED29, Membrane-bound transcription factor site-2 protease, Mupirocin, MYB (gene), Natural computing, Neurotensin, NS5A, Operon, Paracrine signalling, Phlobaphene, Plant disease resistance, Promoter (genetics), Protein inhibitor of activated STAT, PTS Galactitol Family, PTS L-Ascorbate Family, Q-system (genetics), RAP1GAP2, Regulation of gene expression, Regulator gene, Regulatory sequence, Regulon, RegulonDB, Repressor, RFX2, RFX3, Rho-associated protein kinase, Richard H. Ebright, Robert Tjian, Santa J. Ono, Selective estrogen receptor modulator, Siah interacting protein N-terminal domain, SOS box, Squelching, STAT3, TAF protein, TATA box, TCP protein domain, TP53BP2, Transcription (biology), Transcription factor, Transcription factor II A, Transcription factories, Transcriptional activator LAG-3, Transcriptional amplification, Transcriptional regulation, Visna virus, ZC3H12A, Zinc finger chimera, Zinc finger protein 398. Expand index (56 more) »

Activator

Activator may refer to.

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Ada regulon

In DNA repair, the Ada Regulon is a set of genes whose expression is essential to adaptive response (also known as "Ada response", hence the name), which is triggered in prokaryotic cells by exposure to sub-lethal doses of alkylating agents.

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AFF3

AF4/FMR2 family member 3 is a protein that in humans is encoded by the AFF3 gene.

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Aliivibrio fischeri

Aliivibrio fischeri is a Gram-negative, rod-shaped bacterium found globally in marine environments.

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AP-1 transcription factor

Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.

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APC/C activator protein CDH1

Cdh1 is one of the substrate adaptor protein of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae.

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Arc system

The Arc system stands for Anoxic Respiratory Control system.

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ARID2

AT-rich interactive domain-containing protein 2 (ARID2) is a protein that in humans is encoded by the ARID2 gene.

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ASPSCR1

Tether containing UBX domain for GLUT4 (TUG) is a protein that in humans is encoded by the ASPSCR1 gene.

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B-Cell Prolymphocytic Leukemia

B-cell prolymphocytic leukemia, referred to as B-PLL, is a rare blood cancer.

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Bacillus anthracis

Bacillus anthracis is the etiologic agent of anthrax—a common disease of livestock and, occasionally, of humans—and the only obligate pathogen within the genus Bacillus.

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BEND2 (protein)

BEND2 is a protein that in humans is encoded by the BEND2 gene.

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BESS domain

In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32), Suvar(3)7 and Stonewall). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as such it might be related to the myb/SANT HTH domain. The BESS domain directs a variety of protein-protein interactions, including interactions with itself, with Dorsal, and with a TBP-associated factor. It is found in a single copy in Drosophila proteins and is often associated with the MADF domain. Proteins known to contain a BESS domain include.

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Bimolecular fluorescence complementation

Bimolecular fluorescence complementation (also known as BiFC) is a technology typically used to validate protein interactions.

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Bioreporter

Bioreporters are intact, living microbial cells that have been genetically engineered to produce a measurable signal in response to a specific chemical or physical agent in their environment.

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Cas9

Cas9 (CRISPR associated protein 9) is an RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immunity system in Streptococcus pyogenes, among other bacteria.

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Catabolite activator protein

Catabolite activator protein (CAP; also known as cAMP receptor protein, CRP) is a trans-acting transcriptional activator that exists as a homodimer in solution.

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CII protein

cII or transcriptional activator II is a DNA-binding protein and important transcription factor in the life cycle of lambda phage.

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CIITA

CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator.

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CLOCK

Clock (Circadian Locomotor Output Cycles Kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor (CLOCK) that is believed to affect both the persistence and period of circadian rhythms.

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Coactivator (genetics)

A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes.

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Cryptochrome

Cryptochromes (from the Greek κρυπτός χρώμα, "hidden colour") are a class of flavoproteins that are sensitive to blue light.

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DCas9 activation system

dCas9 Activation systems are one type of CRISPR tool that use modified versions of dCas9, a mutation of Cas9 without endonuclease activity, with added transcriptional activators on dCas9 or the guide RNAs (gRNAs).

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Distal promoter

Distal promoter elements are regulatory DNA sequences that can be many kilobases distant from the gene that they regulate.

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Ebola virus

Ebola virus (EBOV, formerly designated Zaire ebolavirus) is one of five known viruses within the genus Ebolavirus.

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Effector (biology)

In biochemistry, an effector molecule is usually a small molecule that selectively binds to a protein and regulates its biological activity.

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ELK1

ETS domain-containing protein Elk-1 is a protein that in humans is encoded by the ELK1 gene.

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Enhancer (genetics)

In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription of a particular gene will occur.

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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ETS transcription factor family

In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six) family is one of the largest families of transcription factors and is unique to animals.

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Feedback

Feedback occurs when outputs of a system are routed back as inputs as part of a chain of cause-and-effect that forms a circuit or loop.

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FNR regulon

The fnr (fumarate and nitrate reductase) gene of Escherichia coli encodes a transcriptional activator (FNR) which is required for the expression of a number of genes involved in anaerobic respiratory pathways.

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FOXM1

Forkhead box protein M1 is a protein that in humans is encoded by the FOXM1 gene.

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G-less cassette

The G-less cassette transcription assay is a method used in molecular biology to determine promoter strength in vitro.

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GAL4/UAS system

The GAL4-UAS system is a biochemical method used to study gene expression and function in organisms such as the fruit fly.

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GATA1

GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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Gene structure

Gene structure is the organisation of specialised sequence elements within a gene.

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General transcription factor

General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific sites (promoter) on DNA to activate transcription of genetic information from DNA to messenger RNA.

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GLI2

Zinc finger protein GLI2 also known as GLI family zinc finger 2 is a protein that in humans is encoded by the GLI2 gene.

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GlnALG operon

The glnALG operon is an operon that regulates the nitrogen content of a cell.

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Glossary of gene expression terms

No description.

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Hedgehog signaling pathway

The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation.

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Histone acetylation and deacetylation

Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and deacetylated as part of gene regulation.

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Histone acetyltransferase

Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε-N-acetyllysine.

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HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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Inducer

In molecular biology, an inducer is a molecule that regulates gene expression.

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Internal control region

An internal control region is a sequence of DNA located with the coding region of eukaryotic genes that binds regulatory elements such as activators or repressors.

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Jeffrey L. Price

Jeffrey L. Price (born 1958) is an American researcher and author in the fields of circadian rhythms and molecular biology.

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Jun dimerization protein

Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene.

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Kruppel-like factors

In molecular genetics, the Krüppel-like family of transcription factors (KLFs) are a set of zinc finger DNA-binding proteins that regulate gene expression.

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L-arabinose operon

The L-arabinose operon, also called the ara or araBAD operon, is an operon required for the breakdown of the five-carbon sugar, L-arabinose, in Escherichia coli.

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Lac operon

The lac operon (lactose operon) is an operon required for the transport and metabolism of lactose in Escherichia coli and many other enteric bacteria.

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LacUV5

LacUV5 is a promoter from the Escherichia coli lac operon which is used in molecular biology to drive gene expression on a plasmid.

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LuxR-type DNA-binding HTH domain

In molecular biology, the LuxR-type DNA-binding HTH domain is a DNA-binding, helix-turn-helix (HTH) domain of about 65 amino acids.

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Maize

Maize (Zea mays subsp. mays, from maíz after Taíno mahiz), also known as corn, is a cereal grain first domesticated by indigenous peoples in southern Mexico about 10,000 years ago.

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MED29

Mediator of RNA polymerase II transcription subunit 29 (Med29) is a transcription suppressor that in humans is encoded by the MED29 gene.

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Membrane-bound transcription factor site-2 protease

Membrane-bound transcription factor site-2 protease, or site-2 protease (S2P) for short, is an enzyme encoded by the gene which liberates the N-terminal fragment of sterol regulatory element-binding protein (SREBP) transcription factors from membranes.

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Mupirocin

Mupirocin, sold under the brand name Bactroban among others, is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis.

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MYB (gene)

Myb proto-oncogene protein also known as transcriptional activator Myb is a protein that in humans is encoded by the MYB gene.

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Natural computing

Natural computing,G.Rozenberg, T.Back, J.Kok, Editors, Handbook of Natural Computing, Springer Verlag, 2012A.Brabazon, M.O'Neill, S.McGarraghy.

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Neurotensin

Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction with the dopaminergic system.

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NS5A

Nonstructural protein 5A (NS5A) is a zinc-binding and proline-rich hydrophilic phosphoprotein that plays a key role in Hepatitis C virus RNA replication.

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Operon

In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter.

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Paracrine signalling

Paracrine signaling is a form of cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior of those cells.

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Phlobaphene

Phlobaphenes (or phlobaphens, CAS No.:71663-19-9) are reddish, alcohol-soluble and water-insoluble phenolic substances.

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Plant disease resistance

Plant disease resistance protects plants from pathogens in two ways: by pre-formed structures and chemicals, and by infection-induced responses of the immune system.

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Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

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Protein inhibitor of activated STAT

Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals.

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PTS Galactitol Family

The PTS Galactitol (Gat) Family is part of the PTS-AG superfamily.

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PTS L-Ascorbate Family

The PTS L-Ascorbate (L-Asc) Family includes porters specific for L-ascorbate, and is part of the PTS-AG superfamily.

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Q-system (genetics)

Q-system is a genetic tool that allows to express transgenes in a living organism.

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RAP1GAP2

RAP1 GTPase activating protein 2 is a protein in humans that is encoded by the RAP1GAP2 gene.

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Regulation of gene expression

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation.

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Regulator gene

A regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes.

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Regulatory sequence

A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism.

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Regulon

In molecular genetics, a regulon is a group of genes that are regulated as a unit, generally controlled by the same regulatory gene that expresses a protein acting as a repressor or activator.

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RegulonDB

RegulonDB is a database of the regulatory network of gene expression in ''Escherichia coli'' K-12.

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Repressor

In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.

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RFX2

DNA-binding protein RFX2 is a protein that in humans is encoded by the RFX2 gene.

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RFX3

Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.

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Rho-associated protein kinase

Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine kinases.

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Richard H. Ebright

Richard High Ebright is an American molecular biologist.

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Robert Tjian

Robert Tjian (born 1949) is an Asian-American biochemist best known for his work on eukaryotic transcription.

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Santa J. Ono

Santa Jeremy Ono (大野三太; born 1962) is a Canadian-American biologist and university administrator.

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Selective estrogen receptor modulator

Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).

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Siah interacting protein N-terminal domain

In molecular biology the protein domain, Siah interacting protein N-terminal domain is found at the N-terminal of the protein, Siah interacting protein (SIP).

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SOS box

SOS box is the region in the promoter of various genes to which the LexA repressor binds to repress the transcription of SOS-induced proteins.

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Squelching

Squelching is a biological phenomenon in which a transcriptional activator acts to inhibit the expression of another gene.

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STAT3

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.

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TAF protein

In molecular biology, TAF refers to a protein named the TATA-binding protein associated factor.

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TATA box

In molecular biology, the TATA box (also called the Goldberg-Hogness box) is a sequence of DNA found in the core promoter region of genes in archaea and eukaryotes.

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TCP protein domain

In molecular biology, the protein domain TCP is actually a family of transcription factors named after: teosinte branched 1 (tb1, Zea mays (Maize)), cycloidea (cyc) (Antirrhinum majus) (Garden snapdragon) and PCF in rice (Oryza sativa).

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TP53BP2

Apoptosis-stimulating of p53 protein 2 (ASPP2) also known as Bcl2-binding protein (Bbp) and tumor suppressor p53-binding protein 2 (p53BP2) is a protein that in humans is encoded by the TP53BP2 gene.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Transcription factor II A

Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA.

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Transcription factories

In genetics, transcription factories describe the discrete sites where transcription occurs in the nucleus.

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Transcriptional activator LAG-3

In molecular biology, the transcriptional activator LAG-3 is a transcriptional activator protein.

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Transcriptional amplification

In genetics, transcriptional amplification is the process in which the total amounts of messenger RNA (mRNA) molecules from expressed genes are increased during disease, development, or in response to stimuli.

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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity.

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Visna virus

Visna virus (also known as visna-maedi virus, maedi-visna virus and ovine lentivirus) from the genus Lentivirus and subfamily Orthoretrovirinae, is a "prototype" retrovirus that causes encephalitis and chronic pneumonitis in sheep.

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ZC3H12A

Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.

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Zinc finger chimera

Zinc finger protein chimera are chimeric proteins composed of a DNA-binding zinc finger protein domain and another domain through which the protein exerts its effect.

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Zinc finger protein 398

Zinc finger protein 398 is a protein that in humans is encoded by the ZNF398 gene.

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Redirects here:

Activator DNA sequences, Activator protein, Activator sequence, Activator sequences, DNA Activation, Transcription activator, Transcription activators, Transcriptional activator, Transcriptional activators.

References

[1] https://en.wikipedia.org/wiki/Activator_(genetics)

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