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HDAC1

Index HDAC1

Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene. [1]

91 relations: Addiction, Androgen receptor, BCL6, Biological effects of radiation on the epigenome, Bromo adjacent homology domain containing 1, BTG2, BUB1B, BUB3, Butyrate, Butyric acid, CBFA2T3, CDC20, CDH1 (gene), CHD3, CHD4, Chromosome 1, COUP-TFII, CTBP1, CTBP2, DDX17, DDX5, DNA (cytosine-5)-methyltransferase 3A, DNMT3L, EED (protein), Entinostat, Epigenetics in learning and memory, Epigenetics in stem-cell differentiation, Epigenetics of diabetes Type 2, FKBP3, FOSB, FUS (gene), GATA1, Histone acetylation and deacetylation, Histone deacetylase, Histone deacetylase 2, Histone deacetylase inhibitor, HMG20B, Homeobox protein TGIF1, Host cell factor C1, HSPA4, HUS1, IFRD1, IKZF1, ING1, Insulin, Interleukin 6, Jun dimerization protein, KMT2A, MAD1L1, Maspin, ..., MBD3, Mdm2, MECOM, Methyl-CpG-binding domain protein 2, Mi-2/NuRD complex, MIER1, Mocetinostat, Mothers against decapentaplegic homolog 2, MTA2, MyoD, NFKB1, Nuclear receptor co-repressor 2, Parthenolide, PHF21A, Prohibitin, Proliferating cell nuclear antigen, Promyelocytic leukemia protein, RAD9A, RBBP4, RBBP7, RCOR1, RELA, Reptin, Retinoblastoma protein, Retinoblastoma-like protein 1, Retinoblastoma-like protein 2, RFC1, SALL4, SAP30, SATB1, SIN3A, SIN3B, Sodium butyrate, Sp1 transcription factor, SPEN, SUDS3, SUV39H1, TOP2A, TOP2B, Zinc finger and BTB domain-containing protein 16, 3,3'-Diindolylmethane. Expand index (41 more) »

Addiction

Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.

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Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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BCL6

B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene.

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Biological effects of radiation on the epigenome

Ionizing radiation can cause biological effects which are passed on to offspring through the epigenome.

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Bromo adjacent homology domain containing 1

Bromo adjacent homology domain containing 1 (BAHD1) is a protein that in humans is encoded by the BAHD1 gene.

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BTG2

Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene.

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BUB1B

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene.

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BUB3

Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.

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Butyrate

Butyrate (also known as butanoate) is the traditional name for the conjugate base of butyric acid (also known as butanoic acid).

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Butyric acid

Butyric acid (from βούτῡρον, meaning "butter"), also known under the systematic name butanoic acid, abbreviated BTA, is a carboxylic acid with the structural formula CH3CH2CH2-COOH.

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CBFA2T3

Protein CBFA2T3 is a protein that in humans is encoded by the CBFA2T3 gene.

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CDC20

The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans.

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CDH1 (gene)

Cadherin-1 also known as CAM 120/80 or epithelial cadherin (E-cadherin) or uvomorulin is a protein that in humans is encoded by the CDH1 gene.

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CHD3

Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene.

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CHD4

Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene.

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Chromosome 1

Chromosome 1 is the designation for the largest human chromosome.

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COUP-TFII

COUP-TFII (COUP transcription factor 2), also known as NR2F2 (nuclear receptor subfamily 2, group F, member 2) is a protein that in humans is encoded by the NR2F2 gene.

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CTBP1

C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene.

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CTBP2

C-terminal-binding protein 2 also known as CtBP2 is a protein that in humans is encoded by the CTBP2 gene.

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DDX17

Probable ATP-dependent RNA helicase DDX17 (p72) is an enzyme that in humans is encoded by the DDX17 gene.

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DDX5

Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.

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DNA (cytosine-5)-methyltransferase 3A

DNA (cytosine-5)-methyltransferase 3A is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation.

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DNMT3L

DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene.

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EED (protein)

Polycomb protein EED is a protein that in humans is encoded by the EED gene.

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Entinostat

Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers.

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Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance.

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Epigenetics in stem-cell differentiation

Embryonic stem cells are capable of self-renewing and differentiating to the desired fate depending on its position within the body.

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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology.

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FKBP3

FK506-binding protein 3 is a protein that in humans is encoded by the FKBP3 gene.

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FOSB

FBJ murine osteosarcoma viral oncogene homolog B, also known as Finkel-Biskis-Jinkins murine osteosarcoma viral oncogene homolog B, FOSB or FosB, is a protein that, in humans, is encoded by the FOSB gene.

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FUS (gene)

RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene.

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GATA1

GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors.

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Histone acetylation and deacetylation

Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and deacetylated as part of gene regulation.

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Histone deacetylase

Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.

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Histone deacetylase 2

Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the HDAC2 gene.

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Histone deacetylase inhibitor

Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are chemical compounds that inhibit histone deacetylases.

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HMG20B

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related is a protein that in humans is encoded by the HMG20B gene.

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Homeobox protein TGIF1

Homeobox protein TGIF1 is a protein that in humans is encoded by the TGIF1 gene.

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Host cell factor C1

Host cell factor 1 (HCFC1, HCF1, or HCF-1), also known as VP16-accessory protein, is a protein that in humans is encoded by the HCFC1 gene.

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HSPA4

Heat shock 70 kDa protein 4 is a protein that in humans is encoded by the HSPA4 gene.

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HUS1

Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.

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IFRD1

Interferon-related developmental regulator 1 is a protein that in humans is encoded by the IFRD1 gene.

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IKZF1

DNA-binding protein Ikaros also known as Ikaros family zinc finger protein 1 is a protein that in humans is encoded by the IKZF1 gene.

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ING1

Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene.

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Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

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Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

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Jun dimerization protein

Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene.

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KMT2A

Histone-lysine N-methyltransferase 2A also known as acute lymphoblastic leukemia 1 (ALL-1), myeloid/lymphoid or mixed-lineage leukemia 1 (MLL1), or zinc finger protein HRX (HRX) is an enzyme that in humans is encoded by the KMT2A gene.

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MAD1L1

Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene.

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Maspin

Maspin (mammary serine protease inhibitor) is a protein that in humans is encoded by the SERPINB5 gene.

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MBD3

Methyl-CpG-binding domain protein 3 is a protein that in humans is encoded by the MBD3 gene.

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Mdm2

Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene.

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MECOM

MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene.

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Methyl-CpG-binding domain protein 2

Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene.

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Mi-2/NuRD complex

In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities.

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MIER1

Mesoderm induction early response protein 1 is a protein that in humans is encoded by the MIER1 gene.

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Mocetinostat

Mocetinostat (MGCD0103) is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma, Hodgkin's lymphoma and acute myelogenous leukemia.

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Mothers against decapentaplegic homolog 2

Mothers against decapentaplegic homolog 2 also known as SMAD family member 2 or SMAD2 is a protein that in humans is encoded by the SMAD2 gene.

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MTA2

Metastasis-associated protein MTA2 is a protein that in humans is encoded by the MTA2 gene.

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MyoD

MyoD is a protein that plays a major role in regulating muscle differentiation.

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NFKB1

Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene.

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Nuclear receptor co-repressor 2

The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains.

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Parthenolide

Parthenolide is a sesquiterpene lactone of the germacranolide class which occurs naturally in the plant feverfew (Tanacetum parthenium), after which it is named.

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PHF21A

PHD finger protein 21A is a protein that in humans is encoded by the PHF21A gene.

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Prohibitin

Prohibitin, also known as PHB, is a protein that in humans is encoded by the PHB gene.

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Proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication.

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Promyelocytic leukemia protein

Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene.

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RAD9A

Cell cycle checkpoint control protein RAD9A is a protein that in humans is encoded by the RAD9A gene.

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RBBP4

Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene.

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RBBP7

Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene.

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RCOR1

REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene.

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RELA

Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene.

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Reptin

Reptin is a tumor repressor protein that is a member of the ATPases Associated with various cellular Activities (AAA+) helicase family and regulates KAI1.

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Retinoblastoma protein

The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers.

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Retinoblastoma-like protein 1

Retinoblastoma-like 1 (p107), also known as RBL1, is a protein that in humans is encoded by the RBL1 gene.

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Retinoblastoma-like protein 2

Retinoblastoma-like protein 2 is a protein that in humans is encoded by the RBL2 gene.

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RFC1

Replication factor C subunit 1 is a protein that in humans is encoded by the RFC1 gene.

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SALL4

Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4.

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SAP30

Sin3A-associated protein, 30kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene.

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SATB1

SATB1 (special AT-rich sequence-binding protein-1) is a protein which in humans is encoded by the SATB1 gene.

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SIN3A

Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene.

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SIN3B

Paired amphipathic helix protein Sin3b is a protein that in humans is encoded by the SIN3B gene.

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Sodium butyrate

Sodium butyrate is a compound with formula Na(C3H7COO).

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Sp1 transcription factor

Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene.

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SPEN

Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.

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SUDS3

Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene.

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SUV39H1

Histone-lysine N-methyltransferase SUV39H1 is an enzyme that in humans is encoded by the SUV39H1 gene.

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TOP2A

DNA topoisomerase 2-alpha is an enzyme that in humans is encoded by the TOP2A gene.

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TOP2B

DNA topoisomerase 2-beta is an enzyme that in humans is encoded by the TOP2B gene.

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Zinc finger and BTB domain-containing protein 16

Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.

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3,3'-Diindolylmethane

3,3′-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and kale.

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HDAC1 (gene), Hdac1, Histone deacetylase 1.

References

[1] https://en.wikipedia.org/wiki/HDAC1

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