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Nuclear receptor coactivator 1

Index Nuclear receptor coactivator 1

The nuclear receptor coactivator 1 is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. [1]

32 relations: Androgen receptor, Aryl hydrocarbon receptor, Basic helix-loop-helix, C-Fos, C-jun, CARM1, CIITA, Coactivator (genetics), Constitutive androstane receptor, CREB-binding protein, Cyclin D1, DDX5, Diffuse large B-cell lymphoma, Epithelioid sarcoma, Estrogen receptor alpha, Glucocorticoid receptor, Histone acetylation and deacetylation, Histone acetyltransferase, NFKB1, Nuclear receptor coregulators, PCAF, Peroxisome proliferator-activated receptor alpha, RAR-related orphan receptor alpha, SNW1, SRA1, STAT3, STAT6, Steroidogenic factor 1, Thiazolidinedione, Thyroid hormone receptor beta, Transcription coregulator, TRIP4.

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Aryl hydrocarbon receptor

The aryl hydrocarbon receptor (AhR or AHR or ahr or ahR) is a protein that in humans is encoded by the AHR gene.

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Basic helix-loop-helix

A basic helix-loop-helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors.

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C-Fos

In the fields of molecular biology and genetics, c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.

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C-jun

c-Jun is a protein that in humans is encoded by the JUN gene.

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CARM1

CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4 (protein arginine N-methyltransferase 4), is an enzyme encoded by the gene found in human beings, as well as many other mammals.

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CIITA

CIITA is a human gene which encodes a protein called the class II, major histocompatibility complex, transactivator.

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Coactivator (genetics)

A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes.

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Constitutive androstane receptor

The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, group I, member 3 is a protein that in humans is encoded by the NR1I3 gene.

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CREB-binding protein

CREB-binding protein, also known as CREBBP or CBP, is a protein that in humans is encoded by the CREBBP gene.

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Cyclin D1

Cyclin D1 is a protein that in humans is encoded by the CCND1 gene.

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DDX5

Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.

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Diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL or DLBL) is a cancer of B cells, a type of white blood cell responsible for producing antibodies.

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Epithelioid sarcoma

Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by epithelioid-like features.

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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Glucocorticoid receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

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Histone acetylation and deacetylation

Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and deacetylated as part of gene regulation.

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Histone acetyltransferase

Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε-N-acetyllysine.

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NFKB1

Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene.

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Nuclear receptor coregulators

Nuclear receptor coregulatorsThis article is based on the transcript of an animated course on the Nuclear Receptor Signaling Atlas (NURSA) website entitled "Nuclear receptor signaling: concepts and models".

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PCAF

P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with p53.

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Peroxisome proliferator-activated receptor alpha

Peroxisome proliferator-activated receptor alpha (PPAR-alpha), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein that in humans is encoded by the PPARA gene.

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RAR-related orphan receptor alpha

RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear receptor that in humans is encoded by the RORA gene.

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SNW1

SNW domain-containing protein 1 is a protein that in humans is encoded by the SNW1 gene.

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SRA1

Steroid receptor RNA activator 1 also known as steroid receptor RNA activator protein (SRAP) is a protein that in humans is encoded by the SRA1 gene.

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STAT3

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.

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STAT6

Signal transducer and activator of transcription 6 (STAT6) is a human gene.

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Steroidogenic factor 1

The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling activity of genes related to the reproductive glands or gonads and adrenal glands.

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Thiazolidinedione

The thiazolidinediones, abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, are a class of heterocyclic compounds consisting of a five-membered C3NS ring.

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Thyroid hormone receptor beta

Thyroid hormone receptor beta (TR-beta) also known as nuclear receptor subfamily 1, group A, member 2 (NR1A2), is a nuclear receptor protein that in humans is encoded by the THRB gene.

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Transcription coregulator

In molecular biology and genetics, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes.

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TRIP4

Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene.

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Redirects here:

NCOA1, NCOA1 (gene), SRC-1, Steroid receptor coactivator 1, Steroid receptor coactivator-1.

References

[1] https://en.wikipedia.org/wiki/Nuclear_receptor_coactivator_1

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