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PDX1

Index PDX1

PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor necessary for pancreatic development, including β-cell maturation, and duodenal differentiation. [1]

20 relations: Development of the digestive system, Epigenetics of diabetes Type 2, Examples of in vitro transdifferentiation by lineage-instructive approach, Fat sand rat, Ginkgotoxin, Homeobox, Induced stem cells, Insulin, List of intestinal epithelial differentiation genes, List of OMIM disorder codes, MAFA (gene), Maturity onset diabetes of the young, MODY 4, Pancreas, Pancreatic progenitor cell, ParaHox, PDX, Transcription factor, Transdifferentiation, Xlox.

Development of the digestive system

The development of the digestive system concerns the epithelium of the digestive system and the parenchyma of its derivatives, which originate from the endoderm.

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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology.

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Examples of in vitro transdifferentiation by lineage-instructive approach

A list of examples of transdifferentiation.

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Fat sand rat

The fat sand rat (Psammomys obesus) is a terrestrial mammal from the gerbil subfamily that is mostly found in North Africa and the Middle East, ranging from Mauritania to the Arabian Peninsula.

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Ginkgotoxin

Ginkgotoxin (4'-O-methylpyridoxine) is a neurotoxin naturally occurring in Ginkgo biloba.

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Homeobox

A homeobox is a DNA sequence, around 180 base pairs long, found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi and plants.

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Induced stem cells

Induced stem cells (iSC) are stem cells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming.

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Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

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List of intestinal epithelial differentiation genes

Table of genes implicated in development and differentiation of the intestinal epithelium The table listed below is a running comprehensive list of all intestinal differential genes that have been reported in the literature.

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List of OMIM disorder codes

This is a list of disorder codes in the Online Mendelian Inheritance in Man (OMIM) database.

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MAFA (gene)

Transcription factor MafA is a protein that in humans is encoded by the MAFA gene.

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Maturity onset diabetes of the young

"Maturity onset diabetes of the young" (MODY) refers to any of several hereditary forms of diabetes mellitus caused by mutations in an autosomal dominant gene disrupting insulin production.

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MODY 4

MODY 4 is a form of maturity onset diabetes of the young.

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Pancreas

The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.

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Pancreatic progenitor cell

Pancreatic progenitor cells are multipotent stem cells originating from the developing fore-gut endoderm which have the ability to differentiate into the lineage specific progenitors responsible for the developing pancreas.

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ParaHox

The ParaHox gene cluster is an array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx, Xlox (Pdx) and Cdx gene families.

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PDX

PDX may refer to.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, is a process in which one mature somatic cell transforms into another mature somatic cell without undergoing an intermediate pluripotent state or progenitor cell type.

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Xlox

The Xlox genes, also called Pdx genes, are a group of genes found in many, but not all, animals.

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Redirects here:

IPF1, Insulin promoter factor 1, Insulin promoter factor-1, Ipf1, PDX1 (gene), Pancreatic and duodenal homeobox protein, Pdx1.

References

[1] https://en.wikipedia.org/wiki/PDX1

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