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Portal hypertension

Index Portal hypertension

Portal hypertension is hypertension (high blood pressure) in the hepatic portal system – made up of the portal vein and its branches, that drain from most of the intestine to the liver. [1]

109 relations: African iron overload, Alcoholic liver disease, Anastomosis, Anorectal varices, Argon plasma coagulation, Ascites, Augustin Nicolas Gilbert, Beta blocker, Biliary atresia, Caput medusae, Cerebroretinal microangiopathy with calcifications and cysts, Cholecystectomy, Circulatory anastomosis, Cirrhosis, Congenital hepatic fibrosis, Cruveilhier–Baumgarten disease, Death of Ludwig van Beethoven, Discovery and development of beta-blockers, Distal splenorenal shunt procedure, Doppler ultrasonography, Epoxyeicosatrienoic acid, Esophageal varices, Esophagus, Falciform ligament, Fetor hepaticus, Fistula, Fowler's solution, Galectin-3, Gandy–Gamna nodules, Gastric antral vascular ectasia, Gastric varices, Gastrointestinal disease, Hassab, Hassab's decongestion operation, Hemolytic anemia, Hemorrhoid, Hepatic portal system, Hepatitis C, Hepatocellular carcinoma, Hepatology, Hepatorenal syndrome, Hepatosplenomegaly, Hereditary hemorrhagic telangiectasia, Hyperdynamic circulation, Hypertension (disambiguation), ICD-10 Chapter XI: Diseases of the digestive system, Intercept Pharmaceuticals, Isosorbide mononitrate, J. Michael Henderson, Johanson–Blizzard syndrome, ..., John Leonard Dawson, Josef Rösch, Left gastric artery, Light chain deposition disease, List of diseases (P), List of eponymously named medical signs, List of hepato-biliary diseases, List of MeSH codes (C06), Liver, Love of Siam, Manto Tshabalala-Msimang, Maurice Villaret, Mohammed Aboul-Fotouh Hassab, Nadolol, Neglected tropical diseases, Nodular regenerative hyperplasia, Non-cirrhotic portal fibrosis, Obeticholic acid, Octreotide, Palmar erythema, Paraumbilical vein, Paul Clemens von Baumgarten, Portacaval anastomosis, Portacaval shunt, Portal hypertensive gastropathy, Portal vein, Portal vein embolization, Portal vein thrombosis, Portal venous pressure, Portopulmonary hypertension, Portosystemic shunt, Primary biliary cholangitis, Primary sclerosing cholangitis, Propranolol, Pulmonary hypertension, Pylephlebitis, Round ligament of liver, Sócrates, Schistosoma mansoni, Schistosomiasis, Selective internal radiation therapy, Serum-ascites albumin gradient, Sheila Sherlock, Shunt (medical), Side stitch, Splenic infarction, Splenic vein, Splenomegaly, Spontaneous bacterial peritonitis, Thomas D. Schiano, Thomas Walter Warnes, Thoracoepigastric vein, Transjugular intrahepatic portosystemic shunt, Umbilical vein, Upper gastrointestinal bleeding, Vascular surgery, Vein, Wilson's disease, 15-Hydroxyeicosatetraenoic acid. Expand index (59 more) »

African iron overload

African iron overload, also known as (Bantu siderosis, or Dietary iron overload), is an iron overload disorder first observed among people of African descent in Southern Africa and Central Africa.

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Alcoholic liver disease

Alcoholic liver disease is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosis or cirrhosis.

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Anastomosis

An anastomosis (plural anastomoses) is a connection or opening between two things (especially cavities or passages) that are normally diverging or branching, such as between blood vessels, leaf veins, or streams.

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Anorectal varices

Anorectal varices are the dilation of collateral submucosal vessels due to backflow in the veins of the rectum.

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Argon plasma coagulation

Argon plasma coagulation or APC is a medical endoscopic procedure used primarily to control bleeding from certain lesions in the gastrointestinal tract, and also sometimes to debulk tumours in the case of patients for whom surgery is not recommended.

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Ascites

Ascites is the abnormal buildup of fluid in the abdomen.

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Augustin Nicolas Gilbert

Augustin Nicolas Gilbert (15 February 1858 – 4 March 1927) was a French physician.

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Beta blocker

Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).

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Biliary atresia

Biliary atresia, also known as extrahepatic ductopenia and progressive obliterative cholangiopathy, is a childhood disease of the liver in which one or more bile ducts are abnormally narrow, blocked, or absent.

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Caput medusae

Caput medusae, also known as palm tree sign, is the appearance of distended and engorged superficial epigastric veins, which are seen radiating from the umbilicus across the abdomen.

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Cerebroretinal microangiopathy with calcifications and cysts

Cerebroretinal microangiopathy with calcifications and cysts (CRMCC) is a rare genetic disorder, which affects multiple organs.

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Cholecystectomy

Cholecystectomy is the surgical removal of the gallbladder.

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Circulatory anastomosis

A circulatory anastomosis is a connection (an anastomosis) between two blood vessels, such as between arteries (arterio-arterial anastomosis), between veins (veno-venous anastomosis) or between an artery and a vein (arterio-venous anastomosis).

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Cirrhosis

Cirrhosis is a condition in which the liver does not function properly due to long-term damage.

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Congenital hepatic fibrosis

Congenital hepatic fibrosis is an inherited fibrocystic liver disease associated with proliferation of interlobular bile ducts within the portal areas and fibrosis that do not alter hepatic lobular architecture.

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Cruveilhier–Baumgarten disease

Cruveilhier–Baumgarten disease or Pégot-Cruveilhier–Baumgarten disease is a rare medical condition in which the umbilical or paraumbilical veins are distended, with an abdominal wall bruit (the Cruveilhier-Baumgarten bruit) and palpable thrill, portal hypertension with splenomegaly, hypersplenism and oesophageal varices, with a normal or small liver.

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Death of Ludwig van Beethoven

Ludwig van Beethoven died on 26 March 1827 at the age of 56, following a prolonged illness.

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Discovery and development of beta-blockers

β adrenergic receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris but are now also used for hypertension, congestive heart failure and certain arrhythmias.

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Distal splenorenal shunt procedure

In medicine, a distal splenorenal shunt procedure (DSRS), also splenorenal shunt procedure and Warren shunt, is a surgical procedure in which the distal splenic vein (a part of the portal venous system) is attached to the left renal vein (a part of the systemic venous system).

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Doppler ultrasonography

Doppler ultrasonography is medical ultrasonography that employs the Doppler effect to generate imaging of the movement of tissues and body fluids (usually blood), and their relative velocity to the probe.

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Epoxyeicosatrienoic acid

The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases.

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Esophageal varices

Esophageal varices (sometimes spelled oesophageal varices) are extremely dilated sub-mucosal veins in the lower third of the esophagus.

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Esophagus

The esophagus (American English) or oesophagus (British English), commonly known as the food pipe or gullet (gut), is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach.

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Falciform ligament

The falciform ligament is a ligament that attaches the liver to the anterior (ventral) body wall, and separates the left lobe into lateral and medial segments.

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Fetor hepaticus

Fetor hepaticus or foetor hepaticus (see spelling differences), also known as breath of the dead or hepatic foetor, is a condition seen in portal hypertension where portosystemic shunting allows thiols to pass directly into the lungs.

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Fistula

A fistula is an abnormal connection between two hollow spaces (technically, two epithelialized surfaces), such as blood vessels, intestines, or other hollow organs.

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Fowler's solution

Fowler's solution is a solution containing 1% potassium arsenite (KAsO2), and once prescribed as a remedy or a tonic.

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Galectin-3

Galectin-3 is a protein that in humans is encoded by the LGALS3 gene.

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Gandy–Gamna nodules

Gandy–Gamna nodules or Gandy-Gamna bodies, sometimes known as Gamna-Gandy bodies or Gamna-Gandy nodules, are small yellow-brown, brown, or rust-colored foci found in the spleen in patients with splenomegaly due to portal hypertension, as well as sickle cell disease.

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Gastric antral vascular ectasia

Gastric antral vascular ectasia (GAVE) is an uncommon cause of chronic gastrointestinal bleeding or iron deficiency anemia.

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Gastric varices

Gastric varices are dilated submucosal veins in the stomach, which can be a life-threatening cause of bleeding in the upper gastrointestinal tract.

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Gastrointestinal disease

Gastrointestinal diseases refer to diseases involving the gastrointestinal tract, namely the esophagus, stomach, small intestine, large intestine and rectum, and the accessory organs of digestion, the liver, gallbladder, and pancreas.

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Hassab

Hassab may refer to.

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Hassab's decongestion operation

Hassab’s decongestion operation is an elective surgical procedure to treat esophageal varices in patients with portal hypertension as a result of cirrhosis of the liver.

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Hemolytic anemia

Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular, but usually in the spleen).

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Hemorrhoid

Hemorrhoids, also called piles, are vascular structures in the anal canal.

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Hepatic portal system

In human anatomy, the hepatic portal system is the system of veins comprising the hepatic portal vein and its tributaries.

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Hepatitis C

Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver.

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Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.

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Hepatology

Hepatology is the branch of medicine that incorporates the study of liver, gallbladder, biliary tree, and pancreas as well as management of their disorders.

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Hepatorenal syndrome

Hepatorenal syndrome (often abbreviated HRS) is a life-threatening medical condition that consists of rapid deterioration in kidney function in individuals with cirrhosis or fulminant liver failure.

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Hepatosplenomegaly

Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).

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Hereditary hemorrhagic telangiectasia

Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease and Osler–Weber–Rendu syndrome, is a rare autosomal dominant genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver, and brain.

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Hyperdynamic circulation

Hyperdynamic circulation is abnormally increased circulatory volume.

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Hypertension (disambiguation)

Hypertension may refer to the following.

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ICD-10 Chapter XI: Diseases of the digestive system

ICD-10 is an international statistical classification used in health care and related industries.

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Intercept Pharmaceuticals

Intercept Pharmaceuticals, Inc. is an American biopharmaceutical company incorporated in 2002, focusing on the development of novel synthetic bile acid analogs to treat chronic liver diseases, such as primary biliary cirrhosis (PBC) now called primary biliary cholangitis, non-alcoholic fatty liver disease (or non-alcoholic steatohepatitis, NASH), cirrhosis, portal hypertension, primary sclerosing cholangitis and also the intestinal disorder, bile acid diarrhea.

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Isosorbide mononitrate

Isosorbide mononitrate is a drug used principally in the treatment of angina pectoris and acts by dilating the blood vessels so as to reduce the blood pressure.

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J. Michael Henderson

J.

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Johanson–Blizzard syndrome

Johanson–Blizzard syndrome (JBS) is a rare, sometimes fatal autosomal recessive multisystem congenital disorder featuring abnormal development of the pancreas, nose and scalp, with mental retardation, hearing loss and growth failure.

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John Leonard Dawson

John Leonard Dawson CVO, FRCS (30 September 1932 – 16 May 1999) was an English surgeon particularly known for his work in the field of liver disease.

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Josef Rösch

Josef Rösch (April 27, 1925 – January 17, 2016) was a researcher and pioneer in vascular and interventional radiology.

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Left gastric artery

In human anatomy, the left gastric artery arises from the celiac artery and runs along the superior portion of the lesser curvature of the stomach.

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Light chain deposition disease

Light chain deposition disease (LCDD) is a rare blood cell disease which is characterized by deposition of fragments of infection-fighting immunoglobulins, called light chains (LCs), in the body.

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List of diseases (P)

This is a list of diseases starting with the letter "P".

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List of eponymously named medical signs

Eponymous medical signs are those that are named after a person or persons, usually the physicians who first described them, but occasionally named after a famous patient.

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List of hepato-biliary diseases

Hepato-biliary diseases include liver diseases and biliary diseases.

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List of MeSH codes (C06)

The following is a list of the "C" codes for MeSH.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Love of Siam

Love of Siam (รักแห่งสยาม,, pronounced) is a 2007 Thai multi-layered romantic-drama film written and directed by Chookiat Sakveerakul.

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Manto Tshabalala-Msimang

Dr.

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Maurice Villaret

Maurice Villaret (7 September 1877 – 25 January 1946) was a French neurologist born in Paris.

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Mohammed Aboul-Fotouh Hassab

Mohammed Aboul-Fotouh Hassab was an Egyptian gastro-intestinal surgeon.

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Nadolol

Nadolol (Corgard) is a non-selective beta blocker used in the treatment of high blood pressure and chest pain.

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Neglected tropical diseases

Neglected tropical diseases (NTDs) are a diverse group of tropical infections which are especially common in low-income populations in developing regions of Africa, Asia, and the Americas.

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Nodular regenerative hyperplasia

Nodular regenerative hyperplasia is a form of liver hyperplasia associated with portal hypertension.

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Non-cirrhotic portal fibrosis

Non-cirrhotic portal fibrosis (NCPF) is a chronic liver disease and type of non-cirrhotic portal hypertension (NCPH).

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Obeticholic acid

Obeticholic acid (abbreviated to OCA, trade name Ocaliva), is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid.

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Octreotide

Octreotide (trade name Sandostatin, among others) is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone.

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Palmar erythema

Palmar erythema is reddening of the palms at the thenar and hypothenar eminences.

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Paraumbilical vein

In the course of the round ligament of liver, small veins (paraumbilical) are found which establish an anastomosis between the veins of the anterior abdominal wall and the hepatic portal, hypogastric, and iliac veins.

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Paul Clemens von Baumgarten

Paul Clemens von Baumgarten (born 28 August 1848, Dresden; died 1928, Tübingen) was a German pathologist.

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Portacaval anastomosis

A portacaval anastomosis (also known as porto-systemic anastomosis or portal caval system) is a specific type of anastomosis that occurs between the veins of the portal circulation and those of the systemic circulation.

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Portacaval shunt

A portacaval shunt (or portal caval shunt) is a treatment for high blood pressure in the liver.

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Portal hypertensive gastropathy

Portal hypertensive gastropathy refers to changes in the mucosa of the stomach in patients with portal hypertension; by far the most common cause of this is cirrhosis of the liver.

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Portal vein

The portal vein or hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver.

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Portal vein embolization

Portal vein embolization (PVE) is a preoperative procedure performed in interventional radiology to initiate hypertrophy of the anticipated future liver remnant a couple weeks prior to a major liver resection procedure.

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Portal vein thrombosis

Portal vein thrombosis is a form of venous thrombosis affecting the hepatic portal vein, which can lead to portal hypertension and reduction in the blood supply to the liver.

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Portal venous pressure

Portal venous pressure is the blood pressure in the hepatic portal vein, and is normally between 5-10 mmHg.

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Portopulmonary hypertension

Portopulmonary hypertension (PPH) is defined by the coexistence of portal and pulmonary hypertension.

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Portosystemic shunt

A portosystemic shunt (PSS), also known as a liver shunt, is a bypass of the liver by the body's circulatory system.

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Primary biliary cholangitis

Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver.

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Primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts which normally allow bile to drain from the gallbladder.

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Propranolol

Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker type. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. It is used to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It can be taken by mouth or by injection into a vein. The formulation that is taken by mouth comes in short-acting and long-acting versions. Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minutes when taken by mouth. Common side effects include nausea, abdominal pain, and constipation. It should not be used in those with an already slow heart rate and most of those with heart failure. Quickly stopping the medication in those with coronary artery disease may worsen symptoms. It may worsen the symptoms of asthma. Caution is recommended in those with liver or kidney problems. Propranolol may cause harmful effects in the baby if taken during pregnancy. Its use during breastfeeding is probably safe, but the baby should be monitored for side effects. It is a non-selective beta blocker which works by blocking β-adrenergic receptors. Propranolol was discovered in 1964. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Propranolol is available as a generic medication. The wholesale cost in the developing world is between 0.24 and 2.16 per month as of 2014. In the United States it costs about $15 per month at a typical dose.

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Pulmonary hypertension

Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure within the arteries of the lungs.

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Pylephlebitis

Pylephlebitis (also called pyelophlebitis and infective suppurative thrombosis of the portal vein) is an uncommon thrombophlebitis of the portal vein or any of its branches (i.e. a portal vein thrombosis) that is caused by infection.

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Round ligament of liver

The round ligament of the liver (or ligamentum teres, or ligamentum teres hepatis) is a degenerative string of tissue that exists in the free edge of the falciform ligament of the liver.

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Sócrates

Sócrates Brasileiro Sampaio de Souza Vieira de Oliveira, MD (19 February 1954 – 4 December 2011), simply known as Sócrates, was a Brazilian footballer who played as an attacking midfielder.

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Schistosoma mansoni

A paired couple of ''Schistosoma mansoni''. Schistosoma mansoni is a water-borne parasite of humans, and belongs to the group of blood flukes (Schistosoma).

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Schistosomiasis

Schistosomiasis, also known as snail fever and bilharzia, is a disease caused by parasitic flatworms called schistosomes.

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Selective internal radiation therapy

Selective internal radiation therapy (SIRT), also known as transarterial radioembolization (TARE), radioembolization or intra-arterial microbrachytherapy is a form of radiation therapy used in interventional radiology to treat cancer.

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Serum-ascites albumin gradient

The serum-ascites albumin gradient or gap (SAAG) is a calculation used in medicine to help determine the cause of ascites.

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Sheila Sherlock

Professor Dame Sheila Patricia Violet Sherlock FRCP FRCPE FRS HFRSE FMGA FCRGA (31 March 1918 – 30 December 2001) was a British physician and medical educator who is considered the major 20th century contributor to the field of hepatology (the study of the liver).

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Shunt (medical)

In medicine, a shunt is a hole or a small passage which moves, or allows movement of, fluid from one part of the body to another.

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Side stitch

Side stitch (also called a side ache, a side cramp, a side crampie, a side sticker or simply a stitch) is an intense stabbing pain under the lower edge of the ribcage that occurs while exercising.

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Splenic infarction

Splenic infarction is a condition in which oxygen supply to the spleen is interrupted, leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ.

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Splenic vein

The splenic vein (formerly the lienal vein) is a blood vessel that drains blood from the spleen, the stomach fundus and part of the pancreas.

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Splenomegaly

Splenomegaly is an enlargement of the spleen.

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Spontaneous bacterial peritonitis

Spontaneous bacterial peritonitis (SBP) is the development of a bacterial infection in the peritoneum causing peritonitis, despite the absence of an obvious source for the infection.

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Thomas D. Schiano

Thomas D. Schiano (born August 12, 1962), M.D., is an American specialist in liver transplantation, intestinal transplantation and in the diagnosis and treatment of acute and chronic liver disease.

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Thomas Walter Warnes

Professor Thomas Walter Warnes MD, FRCP (Lond), born 1938, was an English gastroenterologist.

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Thoracoepigastric vein

The thoracoepigastric vein runs along the lateral aspect of the trunk between the superficial epigastric vein below and the lateral thoracic vein above and establishes an important communication between the femoral vein and axillary vein.

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Transjugular intrahepatic portosystemic shunt

Transjugular intrahepatic portosystemic shunt (TIPS or TIPSS) is an artificial channel within the liver that establishes communication between the inflow portal vein and the outflow hepatic vein.

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Umbilical vein

The umbilical vein is a vein present during fetal development that carries oxygenated blood from the placenta into the growing fetus.

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Upper gastrointestinal bleeding

Upper gastrointestinal bleeding is gastrointestinal bleeding in the upper gastrointestinal tract, commonly defined as bleeding arising from the esophagus, stomach, or duodenum.

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Vascular surgery

Vascular surgery is a surgical subspecialty in which diseases of the vascular system, or arteries, veins and lymphatic circulation, are managed by medical therapy, minimally-invasive catheter procedures, and surgical reconstruction.

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Vein

Veins are blood vessels that carry blood toward the heart.

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Wilson's disease

Wilson's disease is a genetic disorder in which copper builds up in the body.

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15-Hydroxyeicosatetraenoic acid

15-Hydroxyeicosatetraenoic acid (also termed 15-HETE, 15(S)-HETE, and 15S-HETE) is an eicosanoid, i.e. a metabolite of arachidonic acid.

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Hypertension, portal.

References

[1] https://en.wikipedia.org/wiki/Portal_hypertension

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