85 relations: Anabolic steroid, Anemia, Anorexia (symptom), Anorexia nervosa, Antioxidant, Autoimmune disease, Cancer, Cannabinoid, Chronic kidney disease, Chronic obstructive pulmonary disease, Chronic pancreatitis, Coeliac disease, COX-2 inhibitor, Crohn's disease, Cyproheptadine, Cystic fibrosis, Cytokine, Dementia, Diabetes mellitus type 1, Eicosapentaenoic acid, Essential amino acid, Familial amyloid neuropathy, Fatigue, Ghrelin, Gluconeogenesis, Glutamine, Greek language, Growth hormone secretagogue receptor, Heart failure, High-protein diet, HIV/AIDS, Hydrazine, Hypothalamus, Infection, Inflammation, Insulin-like growth factor 1, Interferon, Interferon gamma, Interleukin 1 beta, Interleukin 6, Journal of Cachexia, Sarcopenia and Muscle, Kwashiorkor, Leptin, Lipolysis, Malnutrition, Management of HIV/AIDS, Marasmus, Medical cannabis, Medical sign, Medroxyprogesterone acetate, ..., Megestrol acetate, Mercury poisoning, Metabolic acidosis, Motor neuron disease, Multiple sclerosis, Muscle atrophy, Myofibril, Neoplasm, Neuropeptide Y, NF-κB, Nonsteroidal anti-inflammatory drug, Omega-3 fatty acid, Oncology, Orexigenic, Oxandrolone, Parkinson's disease, Progestin, Progressive disease, Prokinetic agent, Prostaglandin-endoperoxide synthase 2, Proteasome, Proteolysis, Psychiatry, Rheumatoid arthritis, Sarcopenia, Selective androgen receptor modulator, Strength training, Sulindac, Terminal illness, Thalidomide, Tuberculosis, Tumor necrosis factor alpha, Weakness, Weight loss, 5-HT3 antagonist. Expand index (35 more) »
Anabolic steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
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Anemia
Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.
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Anorexia (symptom)
Anorexia (from Ancient Greek ανορεξία: 'ἀν-' "without" + 'όρεξις', spelled 'órexis' meaning "appetite") is the decreased sensation of appetite.
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Anorexia nervosa
Anorexia nervosa, often referred to simply as anorexia, is an eating disorder characterized by low weight, fear of gaining weight, and a strong desire to be thin, resulting in food restriction.
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Antioxidant
Antioxidants are molecules that inhibit the oxidation of other molecules.
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Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Cannabinoid
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.
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Chronic kidney disease
Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.
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Chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a type of obstructive lung disease characterized by long-term breathing problems and poor airflow.
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Chronic pancreatitis
Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions.
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Coeliac disease
Coeliac disease, also spelled celiac disease, is a long-term autoimmune disorder that primarily affects the small intestine.
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COX-2 inhibitor
Selective COX-2 inhibitors are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly targets cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain.
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Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.
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Cyproheptadine
Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties.
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Cystic fibrosis
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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Dementia
Dementia is a broad category of brain diseases that cause a long-term and often gradual decrease in the ability to think and remember that is great enough to affect a person's daily functioning.
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Diabetes mellitus type 1
Diabetes mellitus type 1, also known as type 1 diabetes, is a form of diabetes mellitus in which not enough insulin is produced.
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Eicosapentaenoic acid
Eicosapentaenoic acid (EPA; also icosapentaenoic acid) is an omega-3 fatty acid.
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Essential amino acid
An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized ''de novo'' (from scratch) by the organism, and thus must be supplied in its diet.
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Familial amyloid neuropathy
The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a rare group of autosomal dominant diseases wherein the autonomic nervous system and/or other nerves are compromised by protein aggregation and/or amyloid fibril formation.
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Fatigue
Fatigue is a subjective feeling of tiredness that has a gradual onset.
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Ghrelin
Ghrelin (pronounced), the "hunger hormone", also known as lenomorelin (INN), is a peptide hormone produced by ghrelinergic cells in the gastrointestinal tract which functions as a neuropeptide in the central nervous system.
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Gluconeogenesis
Gluconeogenesis (GNG) is a metabolic pathway that results in the generation of glucose from certain non-carbohydrate carbon substrates.
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Glutamine
Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins.
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Greek language
Greek (Modern Greek: ελληνικά, elliniká, "Greek", ελληνική γλώσσα, ellinikí glóssa, "Greek language") is an independent branch of the Indo-European family of languages, native to Greece and other parts of the Eastern Mediterranean and the Black Sea.
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Growth hormone secretagogue receptor
Growth hormone secretagogue receptor(GHS-R), also known as ghrelin receptor, is a G protein-coupled receptor that binds growth hormone secretagogues (GHSs), such as ghrelin, the "hunger hormone".
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Heart failure
Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.
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High-protein diet
A high-protein diet is often recommended by bodybuilders and nutritionists to help efforts to build muscle and lose fat.
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HIV/AIDS
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).
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Hydrazine
Hydrazine is an inorganic compound with the chemical formula (also written), called diamidogen, archaically.
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Hypothalamus
The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.
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Infection
Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Insulin-like growth factor 1
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene.
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Interferon
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.
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Interferon gamma
Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.
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Interleukin 1 beta
Interleukin 1 beta (IL1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene.
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Interleukin 6
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.
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Journal of Cachexia, Sarcopenia and Muscle
The Journal of Cachexia, Sarcopenia and Muscle is a quarterly peer-reviewed medical journal that covers research relevant to changes in body composition, especially cachexia and sarcopenia, as consequences of chronic illnesses or of the aging process, respectively.
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Kwashiorkor
Kwashiorkor is a form of severe protein malnutrition characterized by edema, and an enlarged liver with fatty infiltrates.
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Leptin
Leptin (from Greek λεπτός leptos, "thin"), "the hormone of energy expenditure", is a hormone predominantly made by adipose cells that helps to regulate energy balance by inhibiting hunger.
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Lipolysis
Lipolysis is the breakdown of lipids and involves hydrolysis of triglycerides into glycerol and free fatty acids.
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Malnutrition
Malnutrition is a condition that results from eating a diet in which one or more nutrients are either not enough or are too much such that the diet causes health problems.
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Management of HIV/AIDS
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection.
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Marasmus
Marasmus is a form of severe malnutrition characterized by energy deficiency.
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Medical cannabis
Medical cannabis, or medical marijuana, is cannabis and cannabinoids that are recommended by doctors for their patients.
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Medical sign
A medical sign is an objective indication of some medical fact or characteristic that may be detected by a patient or anyone, especially a physician, before or during a physical examination of a patient.
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Medroxyprogesterone acetate
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.
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Megestrol acetate
Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia.
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Mercury poisoning
Mercury poisoning is a type of metal poisoning due to mercury exposure.
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Metabolic acidosis
Metabolic acidosis is a condition that occurs when the body produces excessive quantities of acid or when the kidneys are not removing enough acid from the body.
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Motor neuron disease
A motor neuron disease (MND) is any of several neurodegenerative disorders that selectively affect motor neurons, the cells that control voluntary muscles of the body.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Muscle atrophy
Muscle atrophy is defined as a decrease in the mass of the muscle; it can be a partial or complete wasting away of muscle, and is most commonly experienced when persons suffer temporary disabling circumstances such as being restricted in movement and/or confined to bed as when hospitalized.
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Myofibril
A myofibril (also known as a muscle fibril) is a basic rod-like unit of a muscle cell.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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Neuropeptide Y
Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems.
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NF-κB
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.
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Nonsteroidal anti-inflammatory drug
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.
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Omega-3 fatty acid
Omega−3 fatty acids, also called ω−3 fatty acids or n−3 fatty acids, are polyunsaturated fatty acids (PUFAs).
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis, and treatment of cancer.
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Orexigenic
An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia.
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Oxandrolone
Oxandrolone, sold under the brand names Oxandrin and Anavar among others, is an androgen and anabolic steroid (AAS) medication which is used to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications.
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Parkinson's disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
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Progestin
A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Progressive disease
Progressive disease or progressive illness is a disease or physical ailment whose course in most cases is the worsening, growth, or spread of the disease.
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Prokinetic agent
A gastroprokinetic agent, gastrokinetic, or prokinetic, is a type of drug which enhances gastrointestinal motility by increasing the frequency of contractions in the small intestine or making them stronger, but without disrupting their rhythm.
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Prostaglandin-endoperoxide synthase 2
Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (The HUGO official symbol is PTGS2; HGNC ID, HGNC:9605), also known as cyclooxygenase-2 or COX-2, is an enzyme that in humans is encoded by the PTGS2 gene.
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Proteasome
Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
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Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.
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Psychiatry
Psychiatry is the medical specialty devoted to the diagnosis, prevention and treatment of mental disorders.
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Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
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Sarcopenia
Sarcopenia is the degenerative loss of skeletal muscle mass (0.5–1% loss per year after the age of 50), quality, and strength associated with aging.
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Selective androgen receptor modulator
Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands.
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Strength training
Strength training is a type of physical exercise specializing in the use of resistance to induce muscular contraction which builds the strength, anaerobic endurance, and size of skeletal muscles.
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Sulindac
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed in the UK & U.S. by Merck as Clinoril.
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Terminal illness
Terminal illness is an incurable disease that cannot be adequately treated and is reasonably expected to result in the death of the patient.
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Thalidomide
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs.
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).
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Tumor necrosis factor alpha
Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.
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Weakness
Weakness or asthenia is a symptom of a number of different conditions.
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Weight loss
Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue.
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5-HT3 antagonist
The 5-HT3 antagonists, informally known as "setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain.
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References
[1] https://en.wikipedia.org/wiki/Cachexia