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40 relations: Alpha helix, Amino acid, Amphiphile, Asparagine, Biomolecular structure, C-Fos, C-jun, Cytoplasm, Enfuvirtide, England, Envelope glycoprotein GP120, Francis Crick, Gene expression, Gp41, Heptad repeat, Hydrogen bond, Hydrophile, Isoleucine, Keratin, Knobs into holes packing, Leucine, Leucine zipper, Linus Pauling, Nature (journal), Oncogene, Protein, Protein Data Bank, Protein dimer, Protein structure prediction, Protein trimer, Relational database, Spring (device), Structural Classification of Proteins database, Structural motif, Substituent, Thermodynamics, Transcription factor, Tropomyosin, Valine, Van der Waals force.
Alpha helix
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Amphiphile
An amphiphile (from the Greek αμφις, amphis: both and φιλíα, philia: love, friendship) is a chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving) properties.
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Asparagine
Asparagine (symbol Asn or N), is an α-amino acid that is used in the biosynthesis of proteins.
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Biomolecular structure
Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.
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C-Fos
In the fields of molecular biology and genetics, c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.
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C-jun
c-Jun is a protein that in humans is encoded by the JUN gene.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Enfuvirtide
Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.
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England
England is a country that is part of the United Kingdom.
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Envelope glycoprotein GP120
Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope.
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Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was a British molecular biologist, biophysicist, and neuroscientist, most noted for being a co-discoverer of the structure of the DNA molecule in 1953 with James Watson, work which was based partly on fundamental studies done by Rosalind Franklin, Raymond Gosling and Maurice Wilkins.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Gp41
Gp41 also known as glycoprotein 41 is a subunit of the envelope protein complex of retroviruses, including human immunodeficiency virus (HIV).
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Heptad repeat
The heptad repeat is an example of a structural motif that consists of a repeating pattern of seven amino acids: where H represents hydrophobic residues, C represents, typically, charged residues, and P represents polar (and, therefore, hydrophilic) residues.
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Hydrogen bond
A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.
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Hydrophile
A hydrophile is a molecule or other molecular entity that is attracted to water molecules and tends to be dissolved by water.
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Isoleucine
Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins.
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Keratin
Keratin is one of a family of fibrous structural proteins.
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Knobs into holes packing
Knobs into holes packing is a protein folding motif that occurs mainly in alpha helix or coiled coil domains.
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Leucine
Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins.
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Leucine zipper
A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins.
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Linus Pauling
Linus Carl Pauling (February 28, 1901 – August 19, 1994) was an American chemist, biochemist, peace activist, author, educator, and husband of American human rights activist Ava Helen Pauling.
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Nature (journal)
Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein Data Bank
The Protein Data Bank (PDB) is a crystallographic database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids.
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Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
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Protein structure prediction
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its folding and its secondary and tertiary structure from its primary structure.
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Protein trimer
In biochemistry, a protein trimer is a macromolecular complex formed by three, usually non-covalently bound, macromolecules like proteins or nucleic acids.
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Relational database
A relational database is a digital database based on the relational model of data, as proposed by E. F. Codd in 1970.
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Spring (device)
A spring is an elastic object that stores mechanical energy.
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Structural Classification of Proteins database
The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences.
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Structural motif
In a chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a supersecondary structure, which also appears in a variety of other molecules.
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Substituent
In organic chemistry and biochemistry, a substituent is an atom or group of atoms which replaces one or more hydrogen atoms on the parent chain of a hydrocarbon, becoming a moiety of the resultant new molecule.
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Thermodynamics
Thermodynamics is the branch of physics concerned with heat and temperature and their relation to energy and work.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Tropomyosin
Tropomyosin is a two-stranded alpha-helical coiled coil protein found in cell cytoskeletons.
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Valine
Valine (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins.
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Van der Waals force
In molecular physics, the van der Waals forces, named after Dutch scientist Johannes Diderik van der Waals, are distance-dependent interactions between atoms or molecules.
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References
[1] https://en.wikipedia.org/wiki/Coiled_coil
