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29 relations: Allele, Antigen-presenting cell, Autoimmune disease, Coeliac disease, Cytoplasm, Diabetes mellitus type 1, Exon, Gene, Hematopoietic stem cell transplantation, HLA-DQ, HLA-DQ2, HLA-DQ4, HLA-DQ5, HLA-DQ6, HLA-DQ7, HLA-DQ8, HLA-DQ9, Human leukocyte antigen, Immune receptor, Immune system, Locus (genetics), Major histocompatibility complex, MHC class II, Multiple sclerosis, Narcolepsy, Polymorphism (biology), Protein, Protein domain, Transmembrane protein.
Allele
An allele is a variant form of a given gene.
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Antigen-presenting cell
An antigen-presenting cell (APC) or accessory cell is a cell that displays antigen complexed with major histocompatibility complexes (MHCs) on their surfaces; this process is known as antigen presentation.
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Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
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Coeliac disease
Coeliac disease, also spelled celiac disease, is a long-term autoimmune disorder that primarily affects the small intestine.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Diabetes mellitus type 1
Diabetes mellitus type 1, also known as type 1 diabetes, is a form of diabetes mellitus in which not enough insulin is produced.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.
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HLA-DQ
HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells.
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HLA-DQ2
HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system.
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HLA-DQ4
HLA-DQ4 (DQ4) is a serotype subgroup within HLA-DQ(DQ) serotypes.
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HLA-DQ5
HLA-DQ5 (DQ5) is a human leukocyte antigen serotype subgroup within HLA-DQ(DQ) serotypes.
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HLA-DQ6
HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group.
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HLA-DQ7
HLA-DQ7 (DQ7) is an HLA-DQ serotype that recognizes the common HLA DQB1*0301 and the less common HLA DQB1*0304 gene products.
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HLA-DQ8
HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group.
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HLA-DQ9
HLA-DQ9 (DQ9) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group.
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Human leukocyte antigen
The human leukocyte antigen (HLA) system or complex is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans.
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Immune receptor
An immune receptor (or immunologic receptor) is a receptor, usually on a cell membrane, which binds to a substance (for example, a cytokine) and causes a response in the immune system.
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Immune system
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
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Locus (genetics)
A locus (plural loci) in genetics is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker).
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Major histocompatibility complex
The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.
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MHC class II
MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Narcolepsy
Narcolepsy is a long-term neurological disorder that involves a decreased ability to regulate sleep-wake cycles.
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Polymorphism (biology)
Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.
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CELIAC1, Celiac1, HLA-DQB1 (gene), IDDM1, Iddm1.
References
[1] https://en.wikipedia.org/wiki/HLA-DQB1
