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HLA-DR

Index HLA-DR

HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. [1]

44 relations: Antigen-presenting cell, Cell surface receptor, Chromosome 6, Gene conversion, Genetic recombination, Genetics, Graft-versus-host disease, HLA DR3-DQ2, HLA-A, HLA-B, HLA-DPB1, HLA-DQ, HLA-DQB1, HLA-DR1, HLA-DR10, HLA-DR11, HLA-DR12, HLA-DR13, HLA-DR14, HLA-DR15, HLA-DR16, HLA-DR17, HLA-DR18, HLA-DR2, HLA-DR3, HLA-DR4, HLA-DR5, HLA-DR51, HLA-DR52, HLA-DR53, HLA-DR6, HLA-DR7, HLA-DR8, HLA-DR9, HLA-DRA, HLA-DRB1, HLA-DRB3 (gene), HLA-DRB4, HLA-DRB5, Human leukocyte antigen, MHC class II, Population bottleneck, Protein dimer, Protein isoform.

Antigen-presenting cell

An antigen-presenting cell (APC) or accessory cell is a cell that displays antigen complexed with major histocompatibility complexes (MHCs) on their surfaces; this process is known as antigen presentation.

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Cell surface receptor

Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the membranes of cells.

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Chromosome 6

Chromosome 6 is one of the 23 pairs of chromosomes in humans.

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Gene conversion

Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion event.

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Genetic recombination

Genetic recombination (aka genetic reshuffling) is the production of offspring with combinations of traits that differ from those found in either parent.

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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Graft-versus-host disease

Graft-versus-host disease (GvHD) is a medical complication following the receipt of transplanted tissue from a genetically different person.

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HLA DR3-DQ2

HLA DR3-DQ2 is double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype.

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HLA-A

HLA-A is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, which is located at human chromosome 6p21.3.

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HLA-B

HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.

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HLA-DPB1

HLA class II histocompatibility antigen, DP(W2) beta chain is a protein that in humans is encoded by the HLA-DPB1 gene.

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HLA-DQ

HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells.

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HLA-DQB1

Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene.

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HLA-DR1

HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products.

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HLA-DR10

HLA-DR10 (DR10) is a HLA-DR serotype that recognizes the DRB1*1001 gene product.

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HLA-DR11

HLA-DR11 (DR11) is a HLA-DR serotype that recognizes the DRB1*1101 to *1110.

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HLA-DR12

HLA-DR12(DR12) is a HLA-DR serotype that recognizes the DRB1*1201 to *1203, *1206.

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HLA-DR13

HLA-DR13(DR13) is a HLA-DR serotype that recognizes the DRB1*1301 to *13082, *1310 and some other *13 gene products.

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HLA-DR14

HLA-DR14(DR14) is a HLA-DR serotype that recognizes the DRB1*1401 to *1408, *1410 to *1418, and other *14 gene products.

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HLA-DR15

HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products.

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HLA-DR16

HLA-DR16(DR16) is a HLA-DR serotype that recognizes the DRB1*1601, *1602 and *1604 gene products.

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HLA-DR17

HLA-DR17 (DR17) is an HLA-DR serotype that recognizes the DRB1*0301 and *0304 gene products.

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HLA-DR18

HLA-DR18 (DR18) is a HLA-DR serotype that recognizes the DRB1*0302 and *0303 gene products.

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HLA-DR2

HLA-DR2 (DR2) of the HLA-DR serotype system, is a broad antigen serotype that is now preferentially covered by HLA-DR15 and HLA-DR16 serotype group.

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HLA-DR3

HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes.

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HLA-DR4

HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products.

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HLA-DR5

HLA-DR5 (DR5) is a broad-antigen serotype that is further split into HLA-DR11 and HLA-DR12 antigen serotypes.

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HLA-DR51

HLA-DR51 is a HLA-DR serotype that recognizes the antigens encoded by the minor DR locus HLA-DRB5.

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HLA-DR52

HLA-DR52 is an HLA-DR serotype that recognizes gene products of HLA-DRB3 locus.

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HLA-DR53

HLA-DR53 is an HLA-DR serotype that recognizes gene products of HLA-DRB4 locus.

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HLA-DR6

HLA-DR6 (DR6) is a broad-antigen serotype that is further split into HLA-DR13 and HLA-DR14 antigen serotypes.

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HLA-DR7

HLA-DR7 (DR7) is a HLA-DR serotype that recognizes the DRB1*0701 to *0705 gene products.

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HLA-DR8

HLA-DR8 (DR8) is a HLA-DR serotype that recognizes the DRB1*0801 to *0807, and *0810 to *0812 gene products.

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HLA-DR9

HLA-DR09 (DR9) is a HLA-DR serotype that recognizes the DRB1*1001 gene product.

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HLA-DRA

HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene.

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HLA-DRB1

HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene.

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HLA-DRB3 (gene)

HLA class II histocompatibility antigen, DRB3-1 beta chain is a protein that in humans is encoded by the HLA-DRB3 gene.

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HLA-DRB4

Major histocompatibility complex, class II, DR beta 4, also known as HLA-DRB4, is a human gene.

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HLA-DRB5

HLA class II histocompatibility antigen, DRB5 beta chain is a protein that in humans is encoded by the HLA-DRB5 gene.

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Human leukocyte antigen

The human leukocyte antigen (HLA) system or complex is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans.

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MHC class II

MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.

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Population bottleneck

A population bottleneck or genetic bottleneck is a sharp reduction in the size of a population due to environmental events (such as earthquakes, floods, fires, disease, or droughts) or human activities (such as genocide).

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Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

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Protein isoform

A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

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Redirects here:

HLA DR, HLA-DR antigens, Hla-dr antigens, Hladr, MHC II DR.

References

[1] https://en.wikipedia.org/wiki/HLA-DR

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