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Idiopathic pulmonary fibrosis

Index Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a type of chronic lung disease characterized by a progressive and irreversible decline in lung function. [1]

104 relations: Aarhus University Hospital, Acetylcysteine, Acute interstitial pneumonitis, Ambrisentan, American Thoracic Society, Anticoagulant, Antioxidant, Asbestos, Asbestosis, Asthma, Auscultation, Azathioprine, Biopsy, Bosentan, Bronchiectasis, Bronchoalveolar lavage, Chemotherapy, Chest radiograph, Chronic condition, Chronic obstructive pulmonary disease, Collagen, Connective tissue disease, Cough, Crackles, Cryptogenic organizing pneumonia, CT scan, Desquamative interstitial pneumonia, Drug, Eosinophilic pneumonia, European Respiratory Society, Fibroblast, Gastroesophageal reflux disease, Ground-glass opacity, Heart failure, Honeycombing, Hypersensitivity pneumonitis, Hypoxemia, Idiopathic disease, Idiopathic interstitial pneumonia, Immunosuppression, Incidence (epidemiology), Infection, Inflammation, Interferon beta-1a, Interstitial lung disease, Interstitium, Langerhans cell histiocytosis, Life expectancy, Lung, Lung allocation score, ..., Lung biopsy, Lung transplantation, Lung volumes, Lymphocytosis, Malignancy, Mir-29 microRNA precursor, Mixed connective tissue disease, Morphine, Mucin, Mucin 5B, Myofibroblast, Nail clubbing, National Institutes of Health, Nintedanib, Nitrofurantoin, Non-specific interstitial pneumonia, Opioid, Oxygen therapy, Palliative care, Phases of clinical research, Pirfenidone, Plethysmograph, Pneumonia, Prednisone, Pulmonary alveolar proteinosis, Pulmonary embolism, Pulmonary fibrosis, Pulmonary function testing, Pulmonary hypertension, Pulmonary rehabilitation, Pulmonary surfactant, Pulmonology, Radiation-induced lung injury, Radiology, Respiratory disease, Rheumatoid arthritis, Sarcoidosis, Scleroderma, Shortness of breath, Spirometry, Surfactant protein A1, Surfactant protein A2, Symptom, Systemic scleroderma, Telomerase, Telomerase reverse transcriptase, Telomerase RNA component, Thoracoscopy, Thoracotomy, Tobacco smoking, Transforming growth factor beta, Viral disease, Vital capacity, West Highland White Terrier. Expand index (54 more) »

Aarhus University Hospital

Aarhus University Hospital is a large university hospital located in Aarhus in Denmark.

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Acetylcysteine

Acetylcysteine, also known as N-acetylcysteine (NAC), is a medication that is used to treat paracetamol (acetaminophen) overdose, and to loosen thick mucus in individuals with cystic fibrosis or chronic obstructive pulmonary disease.

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Acute interstitial pneumonitis

Acute interstitial pneumonitis (also known as acute interstitial pneumonia or Hamman–Rich syndrome) is a rare, severe lung disease that usually affects otherwise healthy individuals.

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Ambrisentan

Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension.

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American Thoracic Society

The American Thoracic Society (ATS) is a nonprofit organization focused on improving care for pulmonary diseases, critical illnesses and sleep-related breathing disorders.

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Anticoagulant

Anticoagulants, commonly referred to as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time.

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Antioxidant

Antioxidants are molecules that inhibit the oxidation of other molecules.

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Asbestos

Asbestos is a set of six naturally occurring silicate minerals, which all have in common their eponymous asbestiform habit: i.e. long (roughly 1:20 aspect ratio), thin fibrous crystals, with each visible fiber composed of millions of microscopic "fibrils" that can be released by abrasion and other processes.

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Asbestosis

Asbestosis is long term inflammation and scarring of the lungs due to asbestos.

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Auscultation

Auscultation (based on the Latin verb auscultare "to listen") is listening to the internal sounds of the body, usually using a stethoscope.

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Azathioprine

Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication.

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Biopsy

A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease.

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Bosentan

Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH).

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Bronchiectasis

Bronchiectasis is a disease in which there is permanent enlargement of parts of the airways of the lung.

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Bronchoalveolar lavage

Bronchoalveolar lavage (BAL; informally, "bronchoalveolar washing") is a medical procedure in which a bronchoscope is passed through the mouth or nose into the lungs and fluid is squirted into a small part of the lung and then collected for examination.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Chest radiograph

A chest radiograph, colloquially called a chest X-ray (CXR), or chest film, is a projection radiograph of the chest used to diagnose conditions affecting the chest, its contents, and nearby structures.

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Chronic condition

A chronic condition is a human health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time.

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Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a type of obstructive lung disease characterized by long-term breathing problems and poor airflow.

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Collagen

Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies.

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Connective tissue disease

A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology.

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Cough

A cough is a sudden and often repetitively occurring, protective reflex, which helps to clear the large breathing passages from fluids, irritants, foreign particles and microbes.

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Crackles

Crackles, crepitations, or rales are the clicking, rattling, or crackling noises that may be made by one or both lungs of a human with a respiratory disease during inhalation.

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Cryptogenic organizing pneumonia

Cryptogenic organizing pneumonia (COP) also known as bronchiolitis obliterans organizing pneumonia (BOOP, not to be confused with bronchiolitis obliterans) is a form of non-infectious pneumonia; more specifically, COP is an inflammation of the bronchioles (bronchiolitis) and surrounding tissue in the lungs.

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CT scan

A CT scan, also known as computed tomography scan, makes use of computer-processed combinations of many X-ray measurements taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of specific areas of a scanned object, allowing the user to see inside the object without cutting.

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Desquamative interstitial pneumonia

Desquamative interstitial pneumonia is a form of idiopathic interstitial pneumonia featuring elevated levels of macrophages.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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Eosinophilic pneumonia

Eosinophilic pneumonia (EP) is a disease in which an eosinophil, a type of white blood cell, accumulates in the lung.

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European Respiratory Society

The European Respiratory Society, or ERS, is a non-profit organization with offices in Lausanne, Brussels and Sheffield.

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Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Gastroesophageal reflux disease

Gastroesophageal reflux disease (GERD), also known as acid reflux, is a long-term condition where stomach contents come back up into the esophagus resulting in either symptoms or complications.

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Ground-glass opacity

In radiology, ground glass opacity (GGO) is a nonspecific finding on computed tomography (CT) scans that indicates a partial filling of air spaces in the lungs by exudate or transudate, as well as interstitial thickening or partial collapse of lung alveoli.

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Heart failure

Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

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Honeycombing

Honeycombing or "Honeycomb lung" is the radiological appearance seen with widespread fibrosis and is defined by the presence of small cystic spaces with irregularly thickened walls composed of fibrous tissue.

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Hypersensitivity pneumonitis

Hypersensitivity pneumonitis (HP; also called allergic alveolitis, bagpipe lung, or extrinsic allergic alveolitis, EAA) is an inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts.

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Hypoxemia

Hypoxemia (or hypoxaemia in British English) is an abnormally low level of oxygen in the blood.

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Idiopathic disease

An idiopathic disease is any disease with an unknown cause or mechanism of apparently spontaneous origin.

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Idiopathic interstitial pneumonia

Idiopathic interstitial pneumonia (IIP), or noninfectious pneumonia are a class of diffuse lung diseases.

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Immunosuppression

Immunosuppression is a reduction of the activation or efficacy of the immune system.

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Incidence (epidemiology)

Incidence in epidemiology is a measure of the probability of occurrence of a given medical condition in a population within a specified period of time.

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Infection

Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Interferon beta-1a

Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS).

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Interstitial lung disease

Interstitial lung disease (ILD), or diffuse parenchymal lung disease (DPLD), is a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs).

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Interstitium

The interstitium is a contiguous fluid-filled space existing between the skin and the body organs, including muscles and the circulatory system.

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Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes.

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Life expectancy

Life expectancy is a statistical measure of the average time an organism is expected to live, based on the year of its birth, its current age and other demographic factors including gender.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Lung allocation score

The lung allocation score (LAS) is a numerical value used by the United Network for Organ Sharing (UNOS) to assign relative priority for distributing donated lungs for transplantation within the United States.

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Lung biopsy

A lung biopsy is an interventional procedure performed to diagnose lung pathology by obtaining a small piece of lung which is examined under a microscope.

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Lung transplantation

Lung transplantation or pulmonary transplantation is a surgical procedure in which a patient's diseased lungs are partially or totally replaced by lungs which come from a donor.

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Lung volumes

Lung volumes and lung capacities refer to the volume of air associated with different phases of the respiratory cycle.

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Lymphocytosis

Lymphocytosis is an increase in the number of lymphocytes in the blood.

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Malignancy

Malignancy is the tendency of a medical condition to become progressively worse.

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Mir-29 microRNA precursor

The miR-29 microRNA precursor, or pre-miRNA, is a small RNA molecule in the shape of a stem-loop or hairpin.

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Mixed connective tissue disease

Mixed connective tissue disease (also known as Sharp's syndrome), commonly abbreviated as MCTD, is an autoimmune disease characterized by the presence of high blood levels of a specific autoantibody, now called anti-U1 ribonucleoprotein (RNP).

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Morphine

Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.

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Mucin

Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most animals.

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Mucin 5B

Mucin 5B is a protein that in humans is encoded by the MUC5B gene.

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Myofibroblast

A myofibroblast is a cell that is in between a fibroblast and a smooth muscle cell in phenotype.

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Nail clubbing

Nail clubbing, also known as digital clubbing, is a deformity of the finger or toe nails associated with a number of diseases, mostly of the heart and lungs.

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Nintedanib

Nintedanib, marketed under the brand names Ofev and Vargatef, is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF) and along with other medications for some types of non-small-cell lung cancer.

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Nitrofurantoin

Nitrofurantoin, sold under the trade name Macrobid among others, is an antibiotic used to treat bladder infections.

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Non-specific interstitial pneumonia

Non-specific interstitial pneumonia (also known as Non-specific interstitial pneumonitis) (NSIP) is a form of idiopathic interstitial pneumonia.

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Opioid

Opioids are substances that act on opioid receptors to produce morphine-like effects.

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Oxygen therapy

Oxygen therapy, also known as supplemental oxygen, is the use of oxygen as a medical treatment.

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Palliative care

Palliative care is a multidisciplinary approach to specialized medical and nursing care for people with life-limiting illnesses.

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Phases of clinical research

The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.

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Pirfenidone

Pirfenidone is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF).

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Plethysmograph

A plethysmograph is an instrument for measuring changes in volume within an organ or whole body (usually resulting from fluctuations in the amount of blood or air it contains).

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Pneumonia

Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as alveoli.

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Prednisone

Prednisone is a synthetic glucocorticoid drug that is mostly used to suppress the immune system.

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Pulmonary alveolar proteinosis

Pulmonary alveolar proteinosis (PAP) is a group of rare lung disorders characterized by abnormal accumulation of surfactant-derived lipoprotein compounds within the alveoli of the lung.

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Pulmonary embolism

Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream (embolism).

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Pulmonary fibrosis

Pulmonary fibrosis (literally "scarring of the lungs") is a respiratory disease in which scars are formed in the lung tissues, leading to serious breathing problems.

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Pulmonary function testing

Pulmonary function test (PFT) is a complete evaluation of the respiratory system including patient history, physical examinations, and tests of pulmonary function.

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Pulmonary hypertension

Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure within the arteries of the lungs.

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Pulmonary rehabilitation

Pulmonary rehabilitation, also known as respiratory rehabilitation, is an important part of the management and health maintenance of people with chronic respiratory disease who remain symptomatic or continue to have decreased function despite standard medical treatment.

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Pulmonary surfactant

Pulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells.

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Pulmonology

Pulmonology is a medical speciality that deals with diseases involving the respiratory tract.

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Radiation-induced lung injury

Radiation-induced lung injury is a general term for damage to the lungs which occurs as a result of exposure to ionizing radiation.

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Radiology

Radiology is the science that uses medical imaging to diagnose and sometimes also treat diseases within the body.

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Respiratory disease

Respiratory disease is a medical term that encompasses pathological conditions affecting the organs and tissues that make gas exchange possible in higher organisms, and includes conditions of the upper respiratory tract, trachea, bronchi, bronchioles, alveoli, pleura and pleural cavity, and the nerves and muscles of breathing.

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Sarcoidosis

Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.

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Scleroderma

Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs.

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Shortness of breath

Shortness of breath, also known as dyspnea, is the feeling that one cannot breathe well enough.

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Spirometry

Spirometry (meaning the measuring of breath) is the most common of the pulmonary function tests (PFTs).

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Surfactant protein A1

Surfactant protein A1 (SP-A1), also known as Pulmonary surfactant-associated protein A1 (PSP-A) is a protein that in humans is encoded by the SFTPA1 gene.

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Surfactant protein A2

Surfactant protein A2 (SP-A2), also known as Pulmonary surfactant-associated protein A2 (PSP-A2) is a protein that in humans is encoded by the SFTPA2 gene.

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Symptom

A symptom (from Greek σύμπτωμα, "accident, misfortune, that which befalls", from συμπίπτω, "I befall", from συν- "together, with" and πίπτω, "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease.

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Systemic scleroderma

Systemic scleroderma, also called diffuse scleroderma or systemic sclerosis, is an autoimmune disease of the connective tissue.

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Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres.

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Telomerase reverse transcriptase

Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex.

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Telomerase RNA component

| Name.

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Thoracoscopy

Thoracoscopy is a medical procedure involving internal examination, biopsy, and/or resection of disease or masses within the pleural cavity and thoracic cavity.

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Thoracotomy

A thoracotomy is an incision into the pleural space of the chest.

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Tobacco smoking

Tobacco smoking is the practice of smoking tobacco and inhaling tobacco smoke (consisting of particle and gaseous phases).

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Transforming growth factor beta

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.

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Viral disease

A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells.

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Vital capacity

Vital capacity (VC) is the maximum amount of air a person can expel from the lungs after a maximum inhalation.

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West Highland White Terrier

The West Highland White Terrier, commonly known as the Westie, is a breed of dog from Scotland with a distinctive white harsh coat with a somewhat soft white undercoat.

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Cryptogenic fibrosing alveolitis, Fibrosing Alveolitis, Fibrosing alveolitis, Idiopathic Pulmonary Fibrosis, Idiopathic fibrosing alveolitis, Idiopathic fibrotizing alveolitis.

References

[1] https://en.wikipedia.org/wiki/Idiopathic_pulmonary_fibrosis

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