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Nicotinic acid adenine dinucleotide phosphate

Index Nicotinic acid adenine dinucleotide phosphate

Nicotinic acid adenine dinucleotide phosphate, (NAADP), is a Ca2+-mobilizing second messenger synthesised in response to extracellular stimuli. [1]

37 relations: Autophagy, Bafilomycin, British Journal of Pharmacology, Calcium ATPase, Calcium signaling, CD38, Cyclic adenosine monophosphate, Cyclic ADP-ribose, Dihydropyridine, Diltiazem, Dipyridamole, Endoplasmic reticulum, Endosome, Fertilisation, Golgi apparatus, Inositol trisphosphate, Inositol trisphosphate receptor, Lysosome, Monensin, MTOR, Mucolipidosis type IV, Niacin, Nicotinamide, Nicotinamide adenine dinucleotide phosphate, Nigericin, NMDA receptor, Phosphatidylinositol 3,5-bisphosphate, Ryanodine receptor, Science Signaling, Secretion, SERCA, Tert-Butylhydroquinone, Thapsigargin, Transient receptor potential channel, Two-pore channel, V-ATPase, Voltage-gated calcium channel.

Autophagy

Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning "self-devouring" and κύτος kýtos, meaning "hollow") is the natural, regulated, destructive mechanism of the cell that disassembles unnecessary or dysfunctional components.

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Bafilomycin

The bafilomycins are a family of toxic macrolide antibiotic derived from Streptomyces griseus.

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British Journal of Pharmacology

The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.

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Calcium ATPase

Ca2+ ATPase is a form of P-ATPase that transfers calcium after a muscle has contracted.

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Calcium signaling

Calcium (Ca2+) ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins.

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CD38

CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells.

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Cyclic adenosine monophosphate

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes.

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Cyclic ADP-ribose

Cyclic ADP Ribose, frequently abbreviated as cADPR, is a cyclic adenine nucleotide (like cAMP) with two phosphate groups present on 5' OH of the adenosine (like ADP), further connected to another ribose at the 5' position, which, in turn, closes the cycle by glycosidic bonding to the nitrogen 1 (N1) of the same adenine base (whose position N9 has the glycosidic bond to the other ribose).

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Dihydropyridine

Dihydropyridine is a molecule based upon pyridine, and the parent of a class of molecules that have been semi-saturated with two substituents replacing one double bond.

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Diltiazem

Diltiazem (INN) is a nondihydropyridine (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.

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Dipyridamole

Dipyridamole (trademarked as Persantine and others) is a medication that inhibits blood clot formation when given chronically and causes blood vessel dilation when given at high doses over a short time.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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Endosome

In cell biology, an endosome is a membrane-bound compartment inside eukaryotic cells.

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Fertilisation

Fertilisation or fertilization (see spelling differences), also known as generative fertilisation, conception, fecundation, syngamy and impregnation, is the fusion of gametes to initiate the development of a new individual organism.

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Golgi apparatus

The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.

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Inositol trisphosphate

Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells.

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Inositol trisphosphate receptor

Inositol trisphosphate receptor (InsP3R) is a membrane glycoprotein complex acting as a Ca2+ channel activated by inositol trisphosphate (InsP3).

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Lysosome

A lysosome is a membrane-bound organelle found in nearly all animal cells.

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Monensin

Monensin is a polyether antibiotic isolated from Streptomyces cinnamonensis.

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MTOR

The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin and FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene.

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Mucolipidosis type IV

Mucolipidosis type IV (ML IV, ganglioside sialidase deficiency, or ML4) is an autosomal recessive lysosomal storage disorder.

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Niacin

Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient.

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Nicotinamide

Nicotinamide (NAA), also known as niacinamide, is a form of vitamin B3 found in food and used as a dietary supplement and medication.

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Nicotinamide adenine dinucleotide phosphate

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.

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Nigericin

Nigericin is an antibiotic derived from Streptomyces hygroscopicus.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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Phosphatidylinositol 3,5-bisphosphate

Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is one of the seven phosphoinositides found in eukaryotic cell membranes.

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Ryanodine receptor

Ryanodine receptors (RyRs) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons.

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Science Signaling

Science Signaling is a peer-reviewed scientific journal that is published weekly by the American Association for the Advancement of Science (AAAS).

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Secretion

Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.

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SERCA

SERCA, or sarco/endoplasmic reticulum Ca2+-ATPase, or SR Ca2+-ATPase, is a calcium ATPase-type P-ATPase.

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Tert-Butylhydroquinone

tert-Butylhydroquinone (TBHQ, tertiary butylhydroquinone) is a synthetic aromatic organic compound which is a type of phenol.

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Thapsigargin

Thapsigargin is non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA).

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Transient receptor potential channel

Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types.

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Two-pore channel

Two-pore channels (TPCs) are eukaryotic intracellular voltage-gated and ligand gated cation selective ion channels.

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V-ATPase

Vacuolar-type -ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms.

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Voltage-gated calcium channel

Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.

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Redirects here:

NAADP, Nicotinic Acid Adenine Dinucleotide Phosphate.

References

[1] https://en.wikipedia.org/wiki/Nicotinic_acid_adenine_dinucleotide_phosphate

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