Faster access than browser!
41 relations: Addiction, Alzheimer's disease, Anorectic, Aryl, Atomoxetine, Cardiotoxicity, Cell membrane, Cocaine, Depression (mood), Desipramine, Dichloropane, Dissociation constant, Dopamine, Dopamine transporter, Essential amino acid, Experimental and Clinical Psychopharmacology, Heteroatom, Isotopic labeling, Journal of Medicinal Chemistry, List of cocaine analogues, List of phenyltropanes, Monoamine neurotransmitter, Naphthalene, Naphthylaminopropane, Neurotransmitter, Neurotransmitter transporter, Norepinephrine transporter, Obesity, Parkinson's disease, Phenylalanine, Piperidine, Prefrontal cortex, Quinuclidine, Reuptake, RTI International, RTI-112, RTI-229, RTI-336, Serotonin transporter, Serotonin–norepinephrine–dopamine reuptake inhibitor, Tyrosine.
Addiction
Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.
New!!: Phenyltropane and Addiction · See more »
Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
New!!: Phenyltropane and Alzheimer's disease · See more »
Anorectic
An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.
New!!: Phenyltropane and Anorectic · See more »
Aryl
In the context of organic molecules, aryl is any functional group or substituent derived from an aromatic ring, usually an aromatic hydrocarbon, such as phenyl and naphthyl.
New!!: Phenyltropane and Aryl · See more »
Atomoxetine
Atomoxetine, sold under the brand name Strattera among others, is a norepinephrine (noradrenaline) reuptake inhibitor which is approved for the treatment of attention deficit hyperactivity disorder (ADHD).
New!!: Phenyltropane and Atomoxetine · See more »
Cardiotoxicity
Cardiotoxicity is the occurrence of heart electrophysiology dysfunction or muscle damage.
New!!: Phenyltropane and Cardiotoxicity · See more »
Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
New!!: Phenyltropane and Cell membrane · See more »
Cocaine
Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug.
New!!: Phenyltropane and Cocaine · See more »
Depression (mood)
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.
New!!: Phenyltropane and Depression (mood) · See more »
Desipramine
Desipramine, sold under the brand name Norpramin and Pertofrane among others, is a tricyclic antidepressant (TCA) which is used in the treatment of depression.
New!!: Phenyltropane and Desipramine · See more »
Dichloropane
Dichloropane ((−)-2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane, RTI-111, O-401) is a stimulant of the phenyltropane class that acts as a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with IC50 values of 3.13, 0.79 and 18 nM, respectively.
New!!: Phenyltropane and Dichloropane · See more »
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
New!!: Phenyltropane and Dissociation constant · See more »
Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
New!!: Phenyltropane and Dopamine · See more »
Dopamine transporter
The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.
New!!: Phenyltropane and Dopamine transporter · See more »
Essential amino acid
An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized ''de novo'' (from scratch) by the organism, and thus must be supplied in its diet.
New!!: Phenyltropane and Essential amino acid · See more »
Experimental and Clinical Psychopharmacology
Experimental and Clinical Psychopharmacology is a peer-reviewed scientific journal published by the American Psychological Association.
New!!: Phenyltropane and Experimental and Clinical Psychopharmacology · See more »
Heteroatom
In chemistry, a heteroatom (from Ancient Greek heteros, "different", + atomos, "uncut") is any atom that is not carbon or hydrogen.
New!!: Phenyltropane and Heteroatom · See more »
Isotopic labeling
Isotopic labeling (or isotopic labelling) is a technique used to track the passage of an isotope (an atom with a detectable variation) through a reaction, metabolic pathway, or cell.
New!!: Phenyltropane and Isotopic labeling · See more »
Journal of Medicinal Chemistry
The Journal of Medicinal Chemistry is a peer-reviewed medical journal covering research in medicinal chemistry.
New!!: Phenyltropane and Journal of Medicinal Chemistry · See more »
List of cocaine analogues
This is a list of cocaine analogues.
New!!: Phenyltropane and List of cocaine analogues · See more »
List of phenyltropanes
Phenyltropanes (PTs) are a family of chemical compounds originally derived from structural modification of cocaine.
New!!: Phenyltropane and List of phenyltropanes · See more »
Monoamine neurotransmitter
Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.
New!!: Phenyltropane and Monoamine neurotransmitter · See more »
Naphthalene
Naphthalene is an organic compound with formula.
New!!: Phenyltropane and Naphthalene · See more »
Naphthylaminopropane
Naphthylisopropylamine (PAL-287) is an experimental drug currently under investigation for the treatment of alcohol and stimulant addiction.
New!!: Phenyltropane and Naphthylaminopropane · See more »
Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
New!!: Phenyltropane and Neurotransmitter · See more »
Neurotransmitter transporter
Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons.
New!!: Phenyltropane and Neurotransmitter transporter · See more »
Norepinephrine transporter
The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.
New!!: Phenyltropane and Norepinephrine transporter · See more »
Obesity
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.
New!!: Phenyltropane and Obesity · See more »
Parkinson's disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
New!!: Phenyltropane and Parkinson's disease · See more »
Phenylalanine
Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.
New!!: Phenyltropane and Phenylalanine · See more »
Piperidine
Piperidine is an organic compound with the molecular formula (CH2)5NH.
New!!: Phenyltropane and Piperidine · See more »
Prefrontal cortex
In mammalian brain anatomy, the prefrontal cortex (PFC) is the cerebral cortex which covers the front part of the frontal lobe.
New!!: Phenyltropane and Prefrontal cortex · See more »
Quinuclidine
Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block.
New!!: Phenyltropane and Quinuclidine · See more »
Reuptake
Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.
New!!: Phenyltropane and Reuptake · See more »
RTI International
RTI International (formerly Research Triangle Institute) is a nonprofit organization headquartered in the Research Triangle Park in North Carolina that provides research and technical services.
New!!: Phenyltropane and RTI International · See more »
RTI-112
RTI(-4229)-112 (2β-carbomethoxy-3β-(3-methyl-4-chlorophenyl)tropane) is a synthetic stimulant drug from the phenyltropane family.
New!!: Phenyltropane and RTI-112 · See more »
RTI-229
(–)-3β-(4-iodophenyl)tropane-2β-pyrrolidine carboxamide (RTI-4229-229) is a potent and long-lasting stimulant drug which was developed in the 1990s as part of a large group of related analogues from the phenyltropane family.
New!!: Phenyltropane and RTI-229 · See more »
RTI-336
RTI(-4229)-336, (LS-193,309, (−)-2β-(3-(4-methylphenyl)isoxazol-5-yl)-3β-(4-chlorophenyl)tropane) is a phenyltropane derivative which acts as a potent and selective dopamine reuptake inhibitor and stimulant drug.
New!!: Phenyltropane and RTI-336 · See more »
Serotonin transporter
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.
New!!: Phenyltropane and Serotonin transporter · See more »
Serotonin–norepinephrine–dopamine reuptake inhibitor
A serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), also known as a triple reuptake inhibitor (TRI), is a type of drug that acts as a combined reuptake inhibitor of the monoamine neurotransmitters serotonin, norepinephrine, and dopamine.
New!!: Phenyltropane and Serotonin–norepinephrine–dopamine reuptake inhibitor · See more »
Tyrosine
Tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.
New!!: Phenyltropane and Tyrosine · See more »
Redirects here:
References
[1] https://en.wikipedia.org/wiki/Phenyltropane
