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Soluble fms-like tyrosine kinase-1

Index Soluble fms-like tyrosine kinase-1

Soluble fms-like tyrosine kinase-1 (sFlt-1 or sVEGFR-1) is a tyrosine kinase protein with antiangiogenic properties. [1]

49 relations: Acid–base homeostasis, Adenoviridae, Alternative splicing, Angiogenesis inhibitor, Antibody, Biomarker, Brain, Cell adhesion molecule, Chromosome 13, Cornea, Cytotrophoblast, Delayed milestone, Doppler fetal monitor, Drag (physics), Ectodomain, Endothelial dysfunction, Endothelium, Epithelium, Fluid conductance, Gestation, Gravidity and parity, Heparin, Hypertension, Hypoxia (medical), Immunoassay, Isoelectric point, Kidney, Kinase, Liver, Messenger RNA, Monocyte, Nitric oxide, Patau syndrome, Perfusion, Placenta, Placental growth factor, Postpartum period, Pre-eclampsia, Proteinuria, Sensitivity and specificity, Spiral artery, Transmembrane domain, Tyrosine kinase, Tyrosine phosphorylation, Uterus, Vascular endothelial growth factor, Vascular endothelial growth factor A, Vasoconstriction, VEGF receptor.

Acid–base homeostasis

Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF).

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Adenoviridae

Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome.

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Alternative splicing

Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.

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Angiogenesis inhibitor

An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Biomarker

A biomarker, or biological marker, generally refers to a measurable indicator of some biological state or condition.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Cell adhesion molecule

Cell adhesion molecules (CAMs) are proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.

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Chromosome 13

Chromosome 13 is one of the 23 pairs of chromosomes in humans.

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Cornea

The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.

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Cytotrophoblast

The cytotrophoblast (or layer of Langhans) is the inner layer of the trophoblast.

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Delayed milestone

Delayed milestone, also called developmental delays, is used to describe the condition where a child does not reach one of these stages at the expected age.

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Doppler fetal monitor

A Doppler fetal monitor is a hand-held ultrasound transducer used to detect the fetal heartbeat for prenatal care.

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Drag (physics)

In fluid dynamics, drag (sometimes called air resistance, a type of friction, or fluid resistance, another type of friction or fluid friction) is a force acting opposite to the relative motion of any object moving with respect to a surrounding fluid.

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Ectodomain

An ectodomain is the domain of a membrane protein that extends into the extracellular space (the space outside a cell).

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Endothelial dysfunction

In vascular diseases, endothelial dysfunction is a systemic pathological state of the endothelium.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Fluid conductance

Fluid conductance is a measure of how effectively fluids are transported through a medium or a region.

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Gestation

Gestation is the carrying of an embryo or fetus inside viviparous animals.

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Gravidity and parity

In biology and human medicine, gravidity and parity are the number of times a female is or has been pregnant (gravidity) and carried the pregnancies to a viable gestational age (parity).

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Heparin

Heparin, also known as unfractionated heparin (UFH), is medication which is used as an anticoagulant (blood thinner).

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Hypoxia (medical)

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.

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Immunoassay

An immunoassay is a biochemical test that measures the presence or concentration of a macromolecule or a small molecule in a solution through the use of an antibody (usually) or an antigen (sometimes).

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Isoelectric point

The isoelectric point (pI, pH(I), IEP), is the pH at which a particular molecule carries no net electrical charge or is electrically neutral in the statistical mean.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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Patau syndrome

Patau syndrome is a syndrome caused by a chromosomal abnormality, in which some or all of the cells of the body contain extra genetic material from chromosome 13.

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Perfusion

Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue.

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Placenta

The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, thermo-regulation, waste elimination, and gas exchange via the mother's blood supply; to fight against internal infection; and to produce hormones which support pregnancy.

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Placental growth factor

Placental growth factor is a protein that in humans is encoded by the PGF gene.

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Postpartum period

A postpartum (or postnatal) period begins immediately after the birth of a child as the mother's body, including hormone levels and uterus size, returns to a non-pregnant state.

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Pre-eclampsia

Pre-eclampsia (PE) is a disorder of pregnancy characterized by the onset of high blood pressure and often a significant amount of protein in the urine.

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Proteinuria

Proteinuria is the presence of excess proteins in the urine.

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Sensitivity and specificity

Sensitivity and specificity are statistical measures of the performance of a binary classification test, also known in statistics as a classification function.

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Spiral artery

Spiral arteries are small arteries which temporarily supply blood to the endometrium of the uterus during the luteal phase of the menstrual cycle.

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Transmembrane domain

Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.

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Tyrosine kinase

A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.

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Tyrosine phosphorylation

Tyrosine phosphorylation is the addition of a phosphate (PO43−) group to the amino acid tyrosine on a protein.

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Uterus

The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.

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Vascular endothelial growth factor

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.

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Vascular endothelial growth factor A

Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene.

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Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

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VEGF receptor

VEGF receptors are receptors for vascular endothelial growth factor (VEGF).

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Redirects here:

SFlt-1, SFlt1.

References

[1] https://en.wikipedia.org/wiki/Soluble_fms-like_tyrosine_kinase-1

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