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27 relations: Bone marrow suppression, Breast cancer, British Approved Name, Capecitabine, Chemotherapy, Chemotherapy-induced acral erythema, Colorectal cancer, CYP2A6, Dihydropyrimidine dehydrogenase, Dihydropyrimidine dehydrogenase deficiency, Fluorouracil, Gallbladder cancer, Genetic variation, Head and neck cancer, International nonproprietary name, Liver cancer, Lung cancer, Neurotoxicity, Orotate phosphoribosyltransferase, Pancreatic cancer, Prodrug, Stomach cancer, Tegafur/gimeracil/oteracil, Tegafur/uracil, Thymidylate synthase, United States Adopted Name, Zygosity.
Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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British Approved Name
A British Approved Name (BAN) is the official non-proprietary or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP).
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Capecitabine
Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chemotherapy-induced acral erythema
Chemotherapy-induced acral erythema (also known as palmar-plantar erythrodysesthesia, palmoplantar erythrodysesthesia, or hand-foot syndrome) is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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CYP2A6
Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.
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Dihydropyrimidine dehydrogenase
Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation.
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Dihydropyrimidine dehydrogenase deficiency
Dihydropyrimidine dehydrogenase deficiency (DPD deficiency) is an autosomal recessive metabolic disorder in which there is absent or significantly decreased activity of dihydropyrimidine dehydrogenase, an enzyme involved in the metabolism of uracil and thymine.
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Fluorouracil
Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.
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Gallbladder cancer
Gallbladder cancer is a relatively uncommon cancer.
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Genetic variation
Genetic variation means that biological systems – individuals and populations – are different over space.
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Head and neck cancer
Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.
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International nonproprietary name
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
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Liver cancer
Liver cancer, also known as hepatic cancer and primary hepatic cancer, is cancer that starts in the liver.
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Lung cancer
Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
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Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.
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Orotate phosphoribosyltransferase
Orotate phosphoribosyltransferase (OPRTase) or orotic acid phosphoribosyltransferase is an enzyme involved in pyrimidine biosynthesis.
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Pancreatic cancer
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.
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Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
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Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
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Tegafur/gimeracil/oteracil
The combination drug tegafur/gimeracil/oteracil (trade name Teysuno, and TS-1 in Japan), also known as S-1, is used for the treatment of advanced gastric cancer.
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Tegafur/uracil
Tegafur/uracil is a chemotherapy drug combination used in the treatment of cancer, primarily bowel cancer.
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Thymidylate synthase
Thymidylate synthetase is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP).
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United States Adopted Name
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.
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Zygosity
Zygosity is the degree of similarity of the alleles for a trait in an organism.
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Redirects here:
ATC code L01BC03, ATCvet code QL01BC03, C8H9FN2O3, Ftorafur, TS-1, Ts 1.
References
[1] https://en.wikipedia.org/wiki/Tegafur
