Faster access than browser!Similarities between Fluoxetine and Sertraline
Fluoxetine and Sertraline have 62 things in common (in Unionpedia): Active metabolite, Agonist, Allopregnanolone, Alpha-1 adrenergic receptor, Antidepressant, Boxed warning, Breastfeeding, Citalopram, Cognitive behavioral therapy, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, Cytochrome P450, Dextromethorphan, Diarrhea, Dopamine transporter, Enzyme inhibitor, Escitalopram, Fluvoxamine, Food and Drug Administration, Generic drug, Histamine H1 receptor, Imipramine, In vitro, In vivo, Isozyme, Ligand (biochemistry), ..., Liver, Major depressive disorder, Medicines and Healthcare products Regulatory Agency, Metabolism, Monoamine oxidase inhibitor, National Institute for Health and Care Excellence, Nausea, Norepinephrine transporter, Obsessive–compulsive disorder, Oral administration, Panic disorder, Paroxetine, Pimozide, Placebo, Plasma protein binding, Posttraumatic stress disorder, Potency (pharmacology), Pregnancy, Premature ejaculation, Premenstrual dysphoric disorder, Selective serotonin reuptake inhibitor, Seproxetine, Serotonin, Serotonin syndrome, Serotonin transporter, Serotonin–norepinephrine reuptake inhibitor, Sigma-1 receptor, Statistical significance, Tranylcypromine, Tricyclic antidepressant, 5-HT2A receptor, 5-HT2C receptor. Expand index (32 more) »
Active metabolite
An active metabolite is an active form of a drug after it has been processed by the body.
Active metabolite and Fluoxetine · Active metabolite and Sertraline ·
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Agonist and Fluoxetine · Agonist and Sertraline ·
Allopregnanolone
Allopregnanolone, also known as 5α-pregnan-3α-ol-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), as well as brexanolone, is an endogenous inhibitory pregnane neurosteroid.
Allopregnanolone and Fluoxetine · Allopregnanolone and Sertraline ·
Alpha-1 adrenergic receptor
The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein.
Alpha-1 adrenergic receptor and Fluoxetine · Alpha-1 adrenergic receptor and Sertraline ·
Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
Antidepressant and Fluoxetine · Antidepressant and Sertraline ·
Boxed warning
In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears on the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text.
Boxed warning and Fluoxetine · Boxed warning and Sertraline ·
Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
Breastfeeding and Fluoxetine · Breastfeeding and Sertraline ·
Citalopram
Citalopram (brand names: Celexa, Cipramil and others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class.
Citalopram and Fluoxetine · Citalopram and Sertraline ·
Cognitive behavioral therapy
Cognitive-behavioral therapy (CBT) is a psycho-social intervention that is the most widely used evidence-based practice aimed at improving mental health.
Cognitive behavioral therapy and Fluoxetine · Cognitive behavioral therapy and Sertraline ·
CYP1A2
Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.
CYP1A2 and Fluoxetine · CYP1A2 and Sertraline ·
CYP2B6
Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene.
CYP2B6 and Fluoxetine · CYP2B6 and Sertraline ·
CYP2C19
Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme.
CYP2C19 and Fluoxetine · CYP2C19 and Sertraline ·
CYP2C9
Cytochrome P450 2C9 (abbreviated CYP2C9) is an enzyme that in humans is encoded by the CYP2C9 gene.
CYP2C9 and Fluoxetine · CYP2C9 and Sertraline ·
CYP2D6
Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.
CYP2D6 and Fluoxetine · CYP2D6 and Sertraline ·
CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
CYP3A4 and Fluoxetine · CYP3A4 and Sertraline ·
Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
Cytochrome P450 and Fluoxetine · Cytochrome P450 and Sertraline ·
Dextromethorphan
Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties (at higher doses).
Dextromethorphan and Fluoxetine · Dextromethorphan and Sertraline ·
Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
Diarrhea and Fluoxetine · Diarrhea and Sertraline ·
Dopamine transporter
The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.
Dopamine transporter and Fluoxetine · Dopamine transporter and Sertraline ·
Enzyme inhibitor
4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
Enzyme inhibitor and Fluoxetine · Enzyme inhibitor and Sertraline ·
Escitalopram
Escitalopram, sold under the brand names Cipralex and Lexapro among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
Escitalopram and Fluoxetine · Escitalopram and Sertraline ·
Fluvoxamine
Fluvoxamine, sold under the brand name Luvox among others, is a medication which is used primarily for the treatment of obsessive–compulsive disorder (OCD), and is also used to treat major depressive disorder and anxiety disorders such as panic disorder and post-traumatic stress disorder.
Fluoxetine and Fluvoxamine · Fluvoxamine and Sertraline ·
Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
Fluoxetine and Food and Drug Administration · Food and Drug Administration and Sertraline ·
Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
Fluoxetine and Generic drug · Generic drug and Sertraline ·
Histamine H1 receptor
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors.
Fluoxetine and Histamine H1 receptor · Histamine H1 receptor and Sertraline ·
Imipramine
Imipramine, sold under the brand name Tofranil among others, is a tricyclic antidepressant (TCA) which is used mainly in the treatment of depression.
Fluoxetine and Imipramine · Imipramine and Sertraline ·
In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
Fluoxetine and In vitro · In vitro and Sertraline ·
In vivo
Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.
Fluoxetine and In vivo · In vivo and Sertraline ·
Isozyme
Isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.
Fluoxetine and Isozyme · Isozyme and Sertraline ·
Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
Fluoxetine and Ligand (biochemistry) · Ligand (biochemistry) and Sertraline ·
Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
Fluoxetine and Liver · Liver and Sertraline ·
Major depressive disorder
Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.
Fluoxetine and Major depressive disorder · Major depressive disorder and Sertraline ·
Medicines and Healthcare products Regulatory Agency
The Medicines and Healthcare products Regulatory Agency (MHRA) is an executive agency of the Department of Health and Social Care in the United Kingdom which is responsible for ensuring that medicines and medical devices work and are acceptably safe.
Fluoxetine and Medicines and Healthcare products Regulatory Agency · Medicines and Healthcare products Regulatory Agency and Sertraline ·
Metabolism
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
Fluoxetine and Metabolism · Metabolism and Sertraline ·
Monoamine oxidase inhibitor
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).
Fluoxetine and Monoamine oxidase inhibitor · Monoamine oxidase inhibitor and Sertraline ·
National Institute for Health and Care Excellence
The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health in the United Kingdom, which publishes guidelines in four areas.
Fluoxetine and National Institute for Health and Care Excellence · National Institute for Health and Care Excellence and Sertraline ·
Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
Fluoxetine and Nausea · Nausea and Sertraline ·
Norepinephrine transporter
The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.
Fluoxetine and Norepinephrine transporter · Norepinephrine transporter and Sertraline ·
Obsessive–compulsive disorder
Obsessive–compulsive disorder (OCD) is a mental disorder where people feel the need to check things repeatedly, perform certain routines repeatedly (called "rituals"), or have certain thoughts repeatedly (called "obsessions").
Fluoxetine and Obsessive–compulsive disorder · Obsessive–compulsive disorder and Sertraline ·
Oral administration
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Fluoxetine and Oral administration · Oral administration and Sertraline ·
Panic disorder
Panic disorder is an anxiety disorder characterized by reoccurring unexpected panic attacks.
Fluoxetine and Panic disorder · Panic disorder and Sertraline ·
Paroxetine
Paroxetine, also known by trade names including Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, social anxiety disorder, panic disorder, posttraumatic stress disorder, generalized anxiety disorder and premenstrual dysphoric disorder. It has also been used in the treatment of hot flashes and night sweats associated with menopause. It has a similar tolerability profile to other SSRIs. The common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping and delayed ejaculation. It may also be associated with a slightly increased risk of birth defects. The rate of withdrawal symptoms in young people may be higher with paroxetine and venlafaxine than other SSRIs and SNRIs. Several studies have associated paroxetine with suicidal thinking and behavior in children and adolescents. Marketing of the drug began in 1992 by the pharmaceutical company SmithKline Beecham, known since 2000 as GlaxoSmithKline. Generic formulations have been available since 2003 when the patent expired. The United States Department of Justice fined GlaxoSmithKline $3 billion in 2012, including a sum for withholding data on paroxetine, unlawfully promoting it for under-18s and preparing an article, following one of its clinical trials, study 329, that misleadingly reported the drug was effective in treating adolescent depression.
Fluoxetine and Paroxetine · Paroxetine and Sertraline ·
Pimozide
Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class.
Fluoxetine and Pimozide · Pimozide and Sertraline ·
Placebo
A placebo is a substance or treatment of no intended therapeutic value.
Fluoxetine and Placebo · Placebo and Sertraline ·
Plasma protein binding
Plasma protein binding refers to the degree to which medications attach to proteins within the blood.
Fluoxetine and Plasma protein binding · Plasma protein binding and Sertraline ·
Posttraumatic stress disorder
Posttraumatic stress disorder (PTSD)Acceptable variants of this term exist; see the Terminology section in this article.
Fluoxetine and Posttraumatic stress disorder · Posttraumatic stress disorder and Sertraline ·
Potency (pharmacology)
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Fluoxetine and Potency (pharmacology) · Potency (pharmacology) and Sertraline ·
Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
Fluoxetine and Pregnancy · Pregnancy and Sertraline ·
Premature ejaculation
Premature ejaculation (PE) occurs when a man experiences orgasm and expels semen soon after sexual activity and with minimal penile stimulation.
Fluoxetine and Premature ejaculation · Premature ejaculation and Sertraline ·
Premenstrual dysphoric disorder
Premenstrual dysphoric disorder (PMDD) is a severe and disabling form of premenstrual syndrome affecting 3–8% of menstruating women.
Fluoxetine and Premenstrual dysphoric disorder · Premenstrual dysphoric disorder and Sertraline ·
Selective serotonin reuptake inhibitor
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
Fluoxetine and Selective serotonin reuptake inhibitor · Selective serotonin reuptake inhibitor and Sertraline ·
Seproxetine
Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI).
Fluoxetine and Seproxetine · Seproxetine and Sertraline ·
Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
Fluoxetine and Serotonin · Serotonin and Sertraline ·
Serotonin syndrome
Serotonin syndrome (SS) is a group of symptoms that may occur following use of certain serotonergic medications or drugs.
Fluoxetine and Serotonin syndrome · Serotonin syndrome and Sertraline ·
Serotonin transporter
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.
Fluoxetine and Serotonin transporter · Serotonin transporter and Sertraline ·
Serotonin–norepinephrine reuptake inhibitor
Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs that treat major depressive disorder (MDD) and can also treat anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD), chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms.
Fluoxetine and Serotonin–norepinephrine reuptake inhibitor · Serotonin–norepinephrine reuptake inhibitor and Sertraline ·
Sigma-1 receptor
The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor.
Fluoxetine and Sigma-1 receptor · Sertraline and Sigma-1 receptor ·
Statistical significance
In statistical hypothesis testing, a result has statistical significance when it is very unlikely to have occurred given the null hypothesis.
Fluoxetine and Statistical significance · Sertraline and Statistical significance ·
Tranylcypromine
Tranylcypromine (contracted from trans-2-phenylcyclopropylamine; original trade name Parnate)Drugs.com.
Fluoxetine and Tranylcypromine · Sertraline and Tranylcypromine ·
Tricyclic antidepressant
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.
Fluoxetine and Tricyclic antidepressant · Sertraline and Tricyclic antidepressant ·
5-HT2A receptor
The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).
5-HT2A receptor and Fluoxetine · 5-HT2A receptor and Sertraline ·
5-HT2C receptor
The 5-HT2C receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
5-HT2C receptor and Fluoxetine · 5-HT2C receptor and Sertraline ·
The list above answers the following questions
- What Fluoxetine and Sertraline have in common
- What are the similarities between Fluoxetine and Sertraline
Fluoxetine and Sertraline Comparison
Fluoxetine has 162 relations, while Sertraline has 191. As they have in common 62, the Jaccard index is 17.56% = 62 / (162 + 191).
References
This article shows the relationship between Fluoxetine and Sertraline. To access each article from which the information was extracted, please visit:
