CBR96-doxorubicin immunoconjugate

cBR96-doxorubicin immunoconjugate (BMS-182248/SGN-15; also known as cBR96-Dox) is an antibody-drug conjugate or (ADC) directed to the Lewis-Y antigen designed for the treatment of cancer. ^[1]

5 relations: Antibody-drug conjugate, Cancer, Doxorubicin, Lewis antigen system, Seattle Genetics.

Antibody-drug conjugate

Antibody-drug conjugates or ADCs are an important class of highly potent biopharmaceutical drugs designed as a targeted therapy for the treatment of people with cancer.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Doxorubicin

Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer.

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Lewis antigen system

The Lewis antigen system is a human blood group system based upon genes on chromosome 19 p13.3 (FUT3 or Lewis gene) and 19q13.3, (FUT2 or secretor gene).

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Seattle Genetics

Seattle Genetics is a biotechnology company focused on developing and commercializing innovative, empowered monoclonal antibody-based therapies for the treatment of cancer.

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References

[1] https://en.wikipedia.org/wiki/CBR96-doxorubicin_immunoconjugate

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