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EP300

Index EP300

Histone acetyltransferase p300 also known as p300 HAT or E1A-associated protein p300 (where E1A. [1]

89 relations: Androgen receptor, ARNTL, ATG5, BCL3, Binding protein, BRCA1, Bromodomain, CDX2, CEBPB, Chromosome 22, CITED1, CITED2, Coactivation (Transcription), Coactivator (genetics), CREB-binding protein, Diflunisal, DTX1, EGR1, EID1, Epigenome editing, Estrogen receptor alpha, Flap structure-specific endonuclease 1, GPS2 (gene), HIF1A, HIPK2, Histone acetylation and deacetylation, HNF1A, HNRPU, ING4, ING5, Insulin, IRF2, JAK-STAT signaling pathway, KIX domain, KLF15, KLF2, List of MeSH codes (D08), List of MeSH codes (D12.776.930), List of OMIM disorder codes, Long non-coding RNA, Lymphoid enhancer-binding factor 1, MAF (gene), MAML1, Mdm2, MEF2C, MEF2D, Mir-873 microRNA precursor family, MN1 (gene), Mothers against decapentaplegic homolog 2, Mothers against decapentaplegic homolog 7, ..., MYBL2, Myc, Myocyte-specific enhancer factor 2A, MyoD, NCOA6, NFATC2, NPAS2, Nuclear receptor coregulators, NUMB (gene), P300, P300-CBP coactivator family, P53, PCAF, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma, PHD finger, Proliferating cell nuclear antigen, Proneural genes, PROX1, RAR-related orphan receptor alpha, RELA, Retinoblastoma-like protein 1, Rubinstein–Taybi syndrome, SNIP1, SS18, STAT3, STAT6, TAL1, TAZ zinc finger, TCF3, TFAP2A, TGS1, Thyroid hormone receptor alpha, Transcription coregulator, TRERF1, TSG101, Twist transcription factor, YY1, ZZ zinc finger. Expand index (39 more) »

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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ARNTL

Aryl hydrocarbon receptor nuclear translocator-like protein 1 is protein that in humans is encoded by the ARNTL gene, also known as BMAL1, MOP3, and, less commonly, BHLHE5, BMAL, BMAL1C, JAP3, PASD3, and TIC.

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ATG5

Autophagy related 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on Chromosome 6.

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BCL3

B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene.

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Binding protein

A binding protein is any protein that acts as an agent to bind two or more molecules together.

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BRCA1

BRCA1 and BRCA1 are a human gene and its protein product, respectively.

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Bromodomain

A bromodomain is an approximately 110 amino acid protein domain that recognizes acetylated lysine residues, such as those on the N-terminal tails of histones.

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CDX2

Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene.

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CEBPB

CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene.

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Chromosome 22

Chromosome 22 is one of the 23 pairs of chromosomes in human cells.

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CITED1

Cbp/p300-interacting transactivator 1 is a protein that in humans is encoded by the CITED1 gene.

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CITED2

Cbp/p300-interacting transactivator 2 is a protein that in humans is encoded by the CITED2 gene.

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Coactivation (Transcription)

Coactivation is a process by which the transcription of RNA is increased.

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Coactivator (genetics)

A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes.

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CREB-binding protein

CREB-binding protein, also known as CREBBP or CBP, is a protein that in humans is encoded by the CREBBP gene.

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Diflunisal

Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity.

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DTX1

Protein deltex-1 is a protein that in humans is encoded by the DTX1 gene.

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EGR1

EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene.

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EID1

EP300-interacting inhibitor of differentiation 1 is a protein that in humans is encoded by the EID1 gene.

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Epigenome editing

Epigenome editing is a type of genetic engineering in which the epigenome is modified at specific sites using engineered molecules targeted to those sites (as opposed to whole-genome modifications).

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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Flap structure-specific endonuclease 1

Flap endonuclease 1 is an enzyme that in humans is encoded by the FEN1 gene.

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GPS2 (gene)

G protein pathway suppressor 2 is a protein that in humans is encoded by the GPS2 gene.

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HIF1A

Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene.

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HIPK2

Homeodomain-interacting protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene.

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Histone acetylation and deacetylation

Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and deacetylated as part of gene regulation.

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HNF1A

HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human gene on chromosome 12.

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HNRPU

Heterogeneous nuclear ribonucleoprotein U is a protein that in humans is encoded by the HNRNPU gene.

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ING4

Inhibitor of growth protein 4 is a protein that in humans is encoded by the ING4 gene.

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ING5

Inhibitor of growth protein 5 is a protein that in humans is encoded by the ING5 gene.

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Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

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IRF2

Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.

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JAK-STAT signaling pathway

The JAK-STAT signalling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death and tumour formation.

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KIX domain

In biochemistry, the KIX domain (kinase-inducible domain (KID) interacting domain) or CREB binding domain is a protein domain of the eukaryotic transcriptional coactivators CBP and P300.

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KLF15

Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Krüppel-like factor family.

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KLF2

Krüppel-like Factor 2 (KLF2), also known as lung Krüppel-like Factor (LKLF), is a protein that in humans is encoded by the KLF2 gene on chromosome 19.

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List of MeSH codes (D08)

This is the fourth part of the list of the "D" codes for MeSH.

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List of MeSH codes (D12.776.930)

This is a sub-part (transcription factors only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.

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List of OMIM disorder codes

This is a list of disorder codes in the Online Mendelian Inheritance in Man (OMIM) database.

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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are defined as transcripts longer than 200 nucleotides that are not translated into protein.

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Lymphoid enhancer-binding factor 1

Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene.

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MAF (gene)

Transcription factor Maf also known as proto-oncogene c-Maf or V-maf musculoaponeurotic fibrosarcoma oncogene homolog is a transcription factor that in humans is encoded by the MAF gene.

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MAML1

Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene.

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Mdm2

Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene.

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MEF2C

Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene.

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MEF2D

Myocyte-specific enhancer factor 2D is a protein that in humans is encoded by the MEF2D gene.

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Mir-873 microRNA precursor family

In molecular biology mir-873 microRNA is a short RNA molecule.

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MN1 (gene)

MN1 is a gene found on human chromosome 22, with gene map locus 22q12.3-qter.

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Mothers against decapentaplegic homolog 2

Mothers against decapentaplegic homolog 2 also known as SMAD family member 2 or SMAD2 is a protein that in humans is encoded by the SMAD2 gene.

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Mothers against decapentaplegic homolog 7

Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene.

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MYBL2

Myb-related protein B is a protein that in humans is encoded by the MYBL2 gene.

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Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.

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Myocyte-specific enhancer factor 2A

Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene.

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MyoD

MyoD is a protein that plays a major role in regulating muscle differentiation.

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NCOA6

Nuclear receptor coactivator 6 is a protein that in humans is encoded by the NCOA6 gene.

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NFATC2

Nuclear factor of activated T-cells, cytoplasmic 2 is a protein that in humans is encoded by the NFATC2 gene.

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NPAS2

Neuronal PAS domain protein 2 (NPAS2) also known as member of PAS protein 4 (MOP4) is a transcription factor protein that in humans is encoded by the NPAS2 gene.

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Nuclear receptor coregulators

Nuclear receptor coregulatorsThis article is based on the transcript of an animated course on the Nuclear Receptor Signaling Atlas (NURSA) website entitled "Nuclear receptor signaling: concepts and models".

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NUMB (gene)

Protein numb homolog is a protein that in humans is encoded by the NUMB gene.

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P300

P300 may mean.

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P300-CBP coactivator family

The p300-CBP coactivator family is composed of two closely related transcriptional co-activating proteins (or coactivators).

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P53

Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

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PCAF

P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with p53.

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Peroxisome proliferator-activated receptor alpha

Peroxisome proliferator-activated receptor alpha (PPAR-alpha), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein that in humans is encoded by the PPARA gene.

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Peroxisome proliferator-activated receptor gamma

Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone receptor, or NR1C3 (nuclear receptor subfamily 1, group C, member 3) is a type II nuclear receptor that in humans is encoded by the PPARG gene.

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PHD finger

The PHD finger was discovered in 1993 as a Cys4-His-Cys3 motif in the plant homeodomain (hence PHD) proteins HAT3.1 in Arabidopsis thaliana and maize ZmHox1a.

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Proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication.

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Proneural genes

Proneural genes encode transcription factors of the basic helix-loop-helix (bHLH) class which are responsible for the development of neuroectodermal progenitor cells.

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PROX1

Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene.

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RAR-related orphan receptor alpha

RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear receptor that in humans is encoded by the RORA gene.

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RELA

Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene.

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Retinoblastoma-like protein 1

Retinoblastoma-like 1 (p107), also known as RBL1, is a protein that in humans is encoded by the RBL1 gene.

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Rubinstein–Taybi syndrome

Rubinstein–Taybi syndrome (RTS), also known as broad thumb-hallux syndrome or Rubinstein syndrome, is a condition characterized by short stature, moderate to severe learning difficulties, distinctive facial features, and broad thumbs and first toes.

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SNIP1

Smad nuclear-interacting protein 1 is a protein that in humans is encoded by the SNIP1 gene.

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SS18

Protein SSXT is a protein that in humans is encoded by the SS18 gene.

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STAT3

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.

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STAT6

Signal transducer and activator of transcription 6 (STAT6) is a human gene.

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TAL1

T-cell acute lymphocytic leukemia protein 1 (i.e. TAL1 but also termed stem cell leukemia/T-cell acute leukemia 1) is a protein that in humans is encoded by the TAL1 gene.

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TAZ zinc finger

In molecular biology, TAZ zinc finger (Transcription Adaptor putative Zinc finger) domains are zinc-containing domains found in the homologous transcriptional co-activators CREB-binding protein (CBP) and the P300.

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TCF3

Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene.

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TFAP2A

Transcription factor AP-2 alpha (Activating enhancer binding Protein 2 alpha), also known as TFAP2A, is a protein that in humans is encoded by the TFAP2A gene.

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TGS1

Trimethylguanosine synthase is an enzyme that in humans is encoded by the TGS1 gene.

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Thyroid hormone receptor alpha

Thyroid hormone receptor alpha (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear receptor protein that in humans is encoded by the THRA gene.

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Transcription coregulator

In molecular biology and genetics, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes.

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TRERF1

Transcriptional-regulating factor 1 is a protein that in humans is encoded by the TRERF1 gene.

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TSG101

Tumor susceptibility gene 101, also known as TSG101, is a human gene that encodes for a cellular protein of the same name.

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Twist transcription factor

Twist-related protein 1 (TWIST1) also known as class A basic helix-loop-helix protein 38 (bHLHa38) is a basic helix-loop-helix transcription factor that in humans is encoded by the TWIST1 gene.

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YY1

YY1 (Yin Yang 1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene.

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ZZ zinc finger

In molecular biology the ZZ-type zinc finger domain is a type of protein domain that was named because of its ability to bind two zinc ions.

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Redirects here:

E1A binding protein p300, E1a-associated p300 protein, EP300 (gene), P300 (protein).

References

[1] https://en.wikipedia.org/wiki/EP300

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