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Interleukin

Index Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes). [1]

163 relations: Acute-phase protein, Allergy, Alpha 1-antichymotrypsin, Alpha-taxilin, Angiogenesis, Antibody, Astrocyte, Autoimmune disease, B cell, Basophil, Bone marrow, CD4, CD8, Cell adhesion molecule, Cell signaling, Cellular differentiation, Central nervous system, Chemotaxis, Common gamma chain, CSF2RB, CXCL2, Cytokine, Cytotoxic T cell, Dendritic cell, Denileukin diftitox, Endothelium, Eosinophil, Epithelium, Epstein–Barr virus, Equine herpesvirus 2, Ermatingen, Fever, Glycoprotein 130, Granulocyte, Haematopoiesis, Haptoglobin, Hematopoietic stem cell, Hepatocellular carcinoma, Hippocampus, Histamine, Human genome, ICAM-1, IL17RA, IL17RB, IL1A, IL2RA, IL2RB, IL31RA, IL3RA, Immune system, ..., Immunodeficiency, Immunoglobulin A, Immunoglobulin E, Immunoglobulin G, Immunoglobulin M, Immunotherapy, Inflammation, Interferon gamma, Interlaken, Interleukin 1 beta, Interleukin 1 receptor antagonist, Interleukin 1 receptor, type I, Interleukin 1 receptor, type II, Interleukin 10, Interleukin 10 receptor, alpha subunit, Interleukin 10 receptor, beta subunit, Interleukin 11, Interleukin 11 receptor alpha subunit, Interleukin 12, Interleukin 12 receptor, beta 1 subunit, Interleukin 12 receptor, beta 2 subunit, Interleukin 13, Interleukin 15, Interleukin 15 receptor, alpha subunit, Interleukin 16, Interleukin 17, Interleukin 18, Interleukin 19, Interleukin 2, Interleukin 20, Interleukin 20 receptor, alpha subunit, Interleukin 21, Interleukin 22, Interleukin 23, Interleukin 24, Interleukin 25, Interleukin 26, Interleukin 27, Interleukin 27 receptor, alpha subunit, Interleukin 28, Interleukin 29, Interleukin 3, Interleukin 30, Interleukin 31, Interleukin 32, Interleukin 33, Interleukin 35, Interleukin 36, Interleukin 4, Interleukin 5, Interleukin 5 receptor alpha subunit, Interleukin 6, Interleukin 7, Interleukin 8, Interleukin 8 receptor, alpha, Interleukin 8 receptor, beta, Interleukin 9, Interleukin-1 family, Interleukin-13 receptor, Interleukin-18 receptor, Interleukin-20 receptor, Interleukin-21 receptor, Interleukin-22 receptor, Interleukin-23 receptor, Interleukin-28 receptor, Interleukin-4 receptor, Interleukin-6 receptor, Interleukin-7 receptor, Interleukin-9 receptor, International nonproprietary name, Keratinocyte, Long-term potentiation, LY6E, Lymphocyte, Lymphokine, Lymphotoxin alpha, Macrophage, Macrophage inflammatory protein, Mast cell, Measles virus, Melanocyte, Memory T cell, Microorganism, Monocyte, Natural killer cell, Neurogenesis, Neutrophil, Oligodendrocyte, Oprelvekin, Osteoclast, Plasma cell, Protein, Protein primary structure, Psoriasis, Rare disease, Red blood cell, Regulatory T cell, Serum amyloid A, Skin, STAT1, STAT3, Subtypes of HIV, Switzerland, T cell, T helper 17 cell, T helper cell, Tucotuzumab celmoleukin, Tumor necrosis factor alpha, Tumor suppressor, University of Victoria, Vascular tissue, Virus, White blood cell. Expand index (113 more) »

Acute-phase protein

Acute-phase proteins (APPs) are a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation.

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Allergy

Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

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Alpha 1-antichymotrypsin

Alpha 1-antichymotrypsin (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin superfamily.

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Alpha-taxilin

Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA gene.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Astrocyte

Astrocytes (Astro from Greek astron.

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Autoimmune disease

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

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B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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Basophil

Basophils are a type of white blood cells.

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Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

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CD4

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.

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CD8

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR).

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Cell adhesion molecule

Cell adhesion molecules (CAMs) are proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.

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Cell signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Chemotaxis

Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.

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Common gamma chain

The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL-2RG, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor.

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CSF2RB

CSF2RB is a common subunit to the following type I cytokine receptors.

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CXCL2

Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2).

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Cytotoxic T cell

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.

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Dendritic cell

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.

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Denileukin diftitox

Denileukin diftitox (trade name Ontak) was an antineoplastic agent, an engineered protein combining Interleukin-2 and Diphtheria toxin.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Eosinophil

Eosinophils sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While they are released into the bloodstream as neutrophils are, eosinophils reside in tissue They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovary, uterus, spleen, and lymph nodes, but not in the lung, skin, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Epstein–Barr virus

The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.

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Equine herpesvirus 2

Equine herpesvirus 2 (EHV-2) is a virus of the family Herpesviridae, originally known as equine cytomegalovirus due to its slow replication in tissue culture.

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Ermatingen

Ermatingen is a municipality in the district of Kreuzlingen in the canton of Thurgau in Switzerland.

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Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

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Glycoprotein 130

Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta or CD130) is a transmembrane protein which is the founding member of the class of all cytokine receptors.

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Granulocyte

Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.

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Haematopoiesis

Haematopoiesis (from Greek αἷμα, "blood" and ποιεῖν "to make"; also hematopoiesis in American English; sometimes also haemopoiesis or hemopoiesis) is the formation of blood cellular components.

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Haptoglobin

Haptoglobin (abbreviated as Hp) is the protein that in humans is encoded by the HP gene.

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Hematopoietic stem cell

Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.

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Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Histamine

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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Human genome

The human genome is the complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria.

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ICAM-1

ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) is a protein that in humans is encoded by the ICAM1 gene.

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IL17RA

Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene.

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IL17RB

Interleukin-17 receptor B is a protein that in humans is encoded by the IL17RB gene.

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IL1A

Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.

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IL2RA

Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene.

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IL2RB

Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene.

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IL31RA

Interleukin-31 receptor A is a protein that in humans is encoded by the IL31RA gene.

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IL3RA

Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunodeficiency

Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.

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Immunoglobulin A

Immunoglobulin A (IgA, also referred to as sIgA in its secretory form) is an antibody that plays a crucial role in the immune function of mucous membranes.

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Immunoglobulin E

Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.

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Immunoglobulin G

Immunoglobulin G (IgG) is a type of antibody.

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Immunoglobulin M

Immunoglobulin M (IgM) is one of several forms of antibody that are produced by vertebrates.

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Immunotherapy

Immunotherapy is the "treatment of disease by inducing, enhancing, or suppressing an immune response".

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Interferon gamma

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.

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Interlaken

Interlaken (lit.: between lakes) is a statistic town and municipality in the Interlaken-Oberhasli administrative district in the Swiss canton of Bern.

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Interleukin 1 beta

Interleukin 1 beta (IL1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene.

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Interleukin 1 receptor antagonist

The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene.

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Interleukin 1 receptor, type I

Interleukin 1 receptor, type I (IL1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor.

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Interleukin 1 receptor, type II

Interleukin 1 receptor, type II (IL-1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor.

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Interleukin 10

Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.

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Interleukin 10 receptor, alpha subunit

Interleukin 10 receptor, alpha subunit is a subunit for the interleukin-10 receptor.

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Interleukin 10 receptor, beta subunit

Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor.

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Interleukin 11

Interleukin 11 (IL-11) is a protein that in humans is encoded by the IL11 gene.

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Interleukin 11 receptor alpha subunit

Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor.

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Interleukin 12

Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.

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Interleukin 12 receptor, beta 1 subunit

Interleukin-12 receptor, beta 1, or IL-12Rβ1 in short, is a subunit of the interleukin 12 receptor.

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Interleukin 12 receptor, beta 2 subunit

Interleukin 12 receptor, beta 2 subunit is a subunit of the interleukin 12 receptor.

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Interleukin 13

Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene.

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Interleukin 15

Interleukin-15 (IL-15) is a cytokine with structural similarity to Interleukin-2 (IL-2).

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Interleukin 15 receptor, alpha subunit

Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene.

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Interleukin 16

Pro-interleukin-16 is a protein that in humans is encoded by the IL16 gene.

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Interleukin 17

Interleukin 17A (IL-17 or IL-17A) is a pro-inflammatory cytokine.

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Interleukin 18

Interleukin-18 (IL18, also known as interferon-gamma inducing factor) is a protein which in humans is encoded by the IL18 gene.

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Interleukin 19

Interleukin 19 (IL19) is a protein that in humans is encoded by the IL19 gene.

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Interleukin 2

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system.

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Interleukin 20

Interleukin 20 (IL20) is a protein that in humans is encoded by the IL20 gene.

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Interleukin 20 receptor, alpha subunit

Interleukin 20 receptor, alpha subunit is a subunit for the interleukin-20 receptor.

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Interleukin 21

Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene.

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Interleukin 22

Interleukin-22 (IL-22) is protein that in humans is encoded by the IL22 gene.

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Interleukin 23

Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an IL12B (IL-12p40) subunit (that is shared with IL12) and the (IL-23p19) subunit.

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Interleukin 24

Interleukin 24 (IL-24) is a protein that in humans is encoded by the IL24 gene.

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Interleukin 25

Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E) – is a protein that in humans is encoded by the IL25 gene.

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Interleukin 26

Interleukin-26 (IL-26) is a protein that in humans is encoded by the IL26 gene.

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Interleukin 27

Interleukin 27 (IL-27) is a member of the IL-12 cytokine family.

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Interleukin 27 receptor, alpha subunit

Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor.

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Interleukin 28

Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3).

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Interleukin 29

Interleukin-29 (IL-29) is a protein that in humans is encoded by the IL29 gene that resides on chromosome 19.

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Interleukin 3

Interleukin 3 (IL-3) is a protein that in humans is encoded by the IL3 gene.

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Interleukin 30

Interleukin-30 (IL-30) is a protein with a molecular weight of 28 kilodaltons, which forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus is sometimes called IL27-p28.

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Interleukin 31

Interleukin-31 (IL-31) is a protein that in humans is encoded by the IL31 gene that resides on chromosome 12.

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Interleukin 32

Interleukin 32 (Il32) is a protein that in humans is encoded by the IL32 gene.

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Interleukin 33

Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene.

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Interleukin 35

Interleukin 35 (IL-35) is a recently discovered cytokine from the IL-12 family.

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Interleukin 36

Interleukin 36, or IL-36, is a group of cytokines in the IL-1 family with pro-inflammatory effects.

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Interleukin 4

The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.

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Interleukin 5

Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells.

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Interleukin 5 receptor alpha subunit

Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor.

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Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

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Interleukin 7

Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene.

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Interleukin 8

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.

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Interleukin 8 receptor, alpha

Interleukin 8 receptor, alpha is a chemokine receptor.

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Interleukin 8 receptor, beta

Interleukin 8 receptor, beta is a chemokine receptor.

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Interleukin 9

Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins.

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Interleukin-1 family

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults.

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Interleukin-13 receptor

The interleukin-13 receptor is a type I cytokine receptor, binding Interleukin-13.

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Interleukin-18 receptor

The interleukin-18 receptor (IL-18R) is an interleukin receptor of the immunoglobulin superfamily.

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Interleukin-20 receptor

Interleukin-20 receptor is a type II cytokine receptor.

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Interleukin-21 receptor

Interleukin 21 receptor is a type I cytokine receptor.

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Interleukin-22 receptor

Interleukin-22 receptor is a type II cytokine receptor.

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Interleukin-23 receptor

Interleukin-23 receptor is a type I cytokine receptor.

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Interleukin-28 receptor

Interleukin-28 receptor is a type II cytokine receptor.

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Interleukin-4 receptor

The interleukin 4 receptor is a type I cytokine receptor.

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Interleukin-6 receptor

Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor.

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Interleukin-7 receptor

The interleukin-7 receptor is a protein found on the surface of cells.

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Interleukin-9 receptor

Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Keratinocyte

A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there.

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Long-term potentiation

In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity.

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LY6E

Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Lymphokine

Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte.

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Lymphotoxin alpha

Lymphotoxin-alpha (LT-α) or tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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Macrophage inflammatory protein

Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines.

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Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.

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Measles virus

Measles virus (MeV) is a single-stranded, negative-sense, enveloped (non-segmented) RNA virus of the genus Morbillivirus within the family Paramyxoviridae.

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Melanocyte

Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.

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Memory T cell

Memory T cells are a subset of infection- and cancer-fighting T cells (also known as a T lymphocyte) that have previously encountered and responded to their cognate antigen; thus, the term antigen-experienced T cell is often applied.

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Microorganism

A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax. Microorganisms include all unicellular organisms and so are extremely diverse. Of the three domains of life identified by Carl Woese, all of the Archaea and Bacteria are microorganisms. These were previously grouped together in the two domain system as Prokaryotes, the other being the eukaryotes. The third domain Eukaryota includes all multicellular organisms and many unicellular protists and protozoans. Some protists are related to animals and some to green plants. Many of the multicellular organisms are microscopic, namely micro-animals, some fungi and some algae, but these are not discussed here. They live in almost every habitat from the poles to the equator, deserts, geysers, rocks and the deep sea. Some are adapted to extremes such as very hot or very cold conditions, others to high pressure and a few such as Deinococcus radiodurans to high radiation environments. Microorganisms also make up the microbiota found in and on all multicellular organisms. A December 2017 report stated that 3.45 billion year old Australian rocks once contained microorganisms, the earliest direct evidence of life on Earth. Microbes are important in human culture and health in many ways, serving to ferment foods, treat sewage, produce fuel, enzymes and other bioactive compounds. They are essential tools in biology as model organisms and have been put to use in biological warfare and bioterrorism. They are a vital component of fertile soils. In the human body microorganisms make up the human microbiota including the essential gut flora. They are the pathogens responsible for many infectious diseases and as such are the target of hygiene measures.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Natural killer cell

Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.

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Neurogenesis

Neurogenesis is the process by which nervous system cells, known as neurons, are produced by neural stem cells (NSC)s, and it occurs in all species of animals except the porifera (sponges) and placozoans.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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Oligodendrocyte

Oligodendrocytes, or oligodendroglia,.

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Oprelvekin

Oprelvekin is recombinant interleukin eleven (IL-11), a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.

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Osteoclast

An osteoclast is a type of bone cell that breaks down bone tissue.

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Plasma cell

Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that secrete large volumes of antibodies.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein primary structure

Protein primary structure is the linear sequence of amino acids in a peptide or protein.

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Psoriasis

Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.

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Rare disease

A rare disease is any disease that affects a small percentage of the population.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Regulatory T cell

The regulatory T cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.

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Serum amyloid A

Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma.

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Skin

Skin is the soft outer tissue covering vertebrates.

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STAT1

Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene.

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STAT3

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.

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Subtypes of HIV

One of the obstacles to treatment of the human immunodeficiency virus is its high genetic variability.

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Switzerland

Switzerland, officially the Swiss Confederation, is a sovereign state in Europe.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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T helper 17 cell

T helper 17 cells (Th17) are a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17).

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T helper cell

The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.

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Tucotuzumab celmoleukin

Tucotuzumab celmoleukin is an anti-cancer drug.

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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Tumor suppressor

A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.

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University of Victoria

The University of Victoria (UVic) is a major research university located in Victoria, British Columbia, Canada.

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Vascular tissue

Vascular tissue is a complex conducting tissue, formed of more than one cell type, found in vascular plants.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Redirects here:

Interleukin 1β, Interleukins, Receptors, interleukin.

References

[1] https://en.wikipedia.org/wiki/Interleukin

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