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Micronucleus test

Index Micronucleus test

A micronucleus test is a test used in toxicological screening for potential genotoxic compounds. [1]

29 relations: Anaphase, Apoptosis, Bone marrow, Cancerous micronuclei, Carcinogen, Cell culture, Cell nucleus, Centromere, Chromosome, Cytochalasin B, Cytokinesis, Cytoplasm, Flow cytometry, Fluorescence in situ hybridization, Genotoxicity, Giemsa stain, In vitro, In vivo, Lymphocyte, Meiosis, Micronucleus, Mitosis, Mutagen, Necrosis, Nucleated red blood cell, OECD, Polychrome, Red blood cell, Vicia faba.

Anaphase

Anaphase (from the Greek ἀνά, "up" and φάσις, "stage"), is the stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to opposite poles of the cell.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

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Cancerous micronuclei

Cancerous micronuclei is a type of micronucleus that is associated with cancerous cells.

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Carcinogen

A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.

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Cell culture

Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment.

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Centromere

The centromere is the specialized DNA sequence of a chromosome that links a pair of sister chromatids (a dyad).

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Cytochalasin B

Cytochalasin B, the name of which comes from the Greek cytos (cell) and chalasis (relaxation), is a cell-permeable mycotoxin.

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Cytokinesis

Cytokinesis is the part of the cell division process during which the cytoplasm of a single eukaryotic cell divides into two daughter cells.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Flow cytometry

In biotechnology, flow cytometry is a laser- or impedance-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them through an electronic detection apparatus.

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Fluorescence in situ hybridization

Fluorescent in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes that bind to only those parts of the chromosome with a high degree of sequence complementarity.

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Genotoxicity

In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer.

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Giemsa stain

Giemsa stain, named after German chemist and bacteriologist Gustav Giemsa, is used in cytogenetics and for the histopathological diagnosis of malaria and other parasites.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Meiosis

Meiosis (from Greek μείωσις, meiosis, which means lessening) is a specialized type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.

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Micronucleus

Micronucleus is the name given to the small nucleus that forms whenever a chromosome or a fragment of a chromosome is not incorporated into one of the daughter nuclei during cell division.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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Mutagen

In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.

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Necrosis

Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

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Nucleated red blood cell

With the exception of mammals, all vertebrate organisms have hemoglobin-containing cells in their blood and all of these red blood cells contain a nucleus.

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OECD

The Organisation for Economic Co-operation and Development (OECD; Organisation de coopération et de développement économiques, OCDE) is an intergovernmental economic organisation with 35 member countries, founded in 1961 to stimulate economic progress and world trade.

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Polychrome

Polychrome is the "'practice of decorating architectural elements, sculpture, etc., in a variety of colors." The term is used to refer to certain styles of architecture, pottery or sculpture in multiple colors.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Vicia faba

Vicia faba, also known as the broad bean, fava bean, faba bean, field bean, bell bean, or tic bean, is a species of flowering plant in the pea and bean family Fabaceae.

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References

[1] https://en.wikipedia.org/wiki/Micronucleus_test

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