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Oncovirus

Index Oncovirus

An oncovirus is a virus that can cause cancer. [1]

107 relations: Adenoviridae, Adenovirus E1B protein, Adenovirus early region 1A, Adult T-cell leukemia/lymphoma, Advisory Committee on Immunization Practices, Anal cancer, Anthrax, Antigen, Avian sarcoma leukosis virus, Bacillus anthracis, Baruch Samuel Blumberg, Bernice Eddy, Bert Achong, Bradford Hill criteria, Burkitt's lymphoma, Caister Academic Press, Cancer, Carcinogen, Carcinogenesis, Carcinogenic bacteria, Castleman's disease, Cell cycle, Centers for Disease Control and Prevention, Cervical cancer, Chiron, Chiron Corporation, Columbia University, Cyclin E, Cyclin-dependent kinase 2, DNA, DNA virus, E2F, Endogenous retrovirus, Epstein–Barr virus, Food and Drug Administration, Francis Peyton Rous, G1 phase, Gag-onc fusion protein, Gardasil, Genome, Harald zur Hausen, Hepatitis B, Hepatitis B virus, Hepatitis C, Hepatitis C virus, Hepatocellular carcinoma, Hodgkin's lymphoma, HPV vaccines, HPV-positive oropharyngeal cancer, Human cytomegalovirus, ..., Human papillomavirus infection, Human T-lymphotropic virus, Human T-lymphotropic virus 1, International Agency for Research on Cancer, Kaposi's sarcoma, Kaposi's sarcoma-associated herpesvirus, Koch's postulates, Large tumor antigen, List of infectious diseases, List of National Roads in Latvia, Ludwik Gross, Malignant transformation, Merkel cell polyomavirus, Merkel-cell carcinoma, Michael A. Epstein, Michael Houghton (virologist), Mouse mammary tumor virus, Mucoepidermoid carcinoma, Murine polyomavirus, Nasopharynx cancer, National Institutes of Health, Neoplasm, Oncogene, Oncolytic virus, P107, P53, Patrick S. Moore, Penile cancer, Plasmid, Polyomaviridae, Post-transplant lymphoproliferative disorder, Primary effusion lymphoma, Promoter (genetics), R. Palmer Beasley, Representational difference analysis, Retinoblastoma protein, Retrovirus, Richard Shope, RNA, RNA virus, Robert Gallo, Robert Koch, Rous sarcoma virus, S phase, Sarah Stewart (cancer researcher), Shope papilloma virus, SV40, Transcriptome, UBE3A, Ubiquitin, University of Pittsburgh Cancer Institute, Viral hepatitis, Virus, Vulvar cancer, World Health Organization, Yuan Chang, Yvonne Barr. Expand index (57 more) »

Adenoviridae

Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome.

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Adenovirus E1B protein

Adenovirus E1B protein usually refers to one of two proteins transcribed from the E1B gene of the adenovirus: a 55kDa protein and a 19kDa protein.

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Adenovirus early region 1A

Adenovirus early region 1A (E1a or E1A) is a gene expressed during adenovirus replication to produce a variety of (E1A) proteins.

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Adult T-cell leukemia/lymphoma

Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare cancer of the immune system's own T-cells.

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Advisory Committee on Immunization Practices

The Advisory Committee on Immunization Practices (ACIP), founded in 1964, provides advice and guidance on effective control of vaccine-preventable diseases in the U.S. civilian population.

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Anal cancer

Anal cancer is a cancer (malignant tumor) which arises from the anus, the distal opening of the gastrointestinal tract.

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Anthrax

Anthrax is an infection caused by the bacterium Bacillus anthracis.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Avian sarcoma leukosis virus

Avian sarcoma leukosis virus (ASLV) is an endogenous retrovirus that infects and can lead to cancer in chickens; experimentally it can infect other species of birds and mammals.

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Bacillus anthracis

Bacillus anthracis is the etiologic agent of anthrax—a common disease of livestock and, occasionally, of humans—and the only obligate pathogen within the genus Bacillus.

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Baruch Samuel Blumberg

Baruch Samuel Blumberg (July 28, 1925April 5, 2011) — known as Barry Blumberg — was an American physician, geneticist, and co-recipient of the 1976 Nobel Prize in Physiology or Medicine (with Daniel Carleton Gajdusek), for his work on the hepatitis B virus while an investigator at the NIH.

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Bernice Eddy

Bernice Eddy (1903–1989) was an American virologist and epidemiologist.

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Bert Achong

Bert Geoffrey Achong (6 December 1928 - 20 November 1996) was a Trinidadian pathologist.

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Bradford Hill criteria

The Bradford Hill criteria, otherwise known as Hill's criteria for causation, are a group of 9 principles, established in 1965 by the English epidemiologist Sir Austin Bradford Hill.

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Burkitt's lymphoma

Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center.

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Caister Academic Press

Caister Academic Press is an independent academic publishing company that produces books and ebooks on microbiology, and molecular biology.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Carcinogen

A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.

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Carcinogenesis

Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.

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Carcinogenic bacteria

Cancer bacteria are bacteria infectious organisms that are known or suspected to cause cancer.

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Castleman's disease

Castleman disease is a group of uncommon lymphoproliferative disorders characterized by lymph node enlargement, characteristic features on microscopic analysis of enlarged lymph node tissue, and a range of symptoms and clinical findings.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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Centers for Disease Control and Prevention

The Centers for Disease Control and Prevention (CDC) is the leading national public health institute of the United States.

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Cervical cancer

Cervical cancer is a cancer arising from the cervix.

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Chiron

In Greek mythology, Chiron (also Cheiron or Kheiron; Χείρων "hand") was held to be the superlative centaur amongst his brethren, as he was called as the "wisest and justest of all the centaurs".

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Chiron Corporation

Chiron Corporation was an American multinational biotechnology firm based in Emeryville, California that was acquired by Novartis International AG on April 20, 2006.

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Columbia University

Columbia University (Columbia; officially Columbia University in the City of New York), established in 1754, is a private Ivy League research university in Upper Manhattan, New York City.

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Cyclin E

Cyclin E is a member of the cyclin family.

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Cyclin-dependent kinase 2

Cyclin-dependent kinase 2, also known as cell division protein kinase 2, is an enzyme that in humans is encoded by the CDK2 gene.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA virus

A DNA virus is a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase.

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E2F

E2F is a group of genes that codifies a family of transcription factors (TF) in higher eukaryotes.

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Endogenous retrovirus

Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses.

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Epstein–Barr virus

The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Francis Peyton Rous

Francis Peyton Rous (October 5, 1879 – February 16, 1970) was an American Nobel Prize-winning virologist.

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G1 phase

The g1 phase, or Gap 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division.

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Gag-onc fusion protein

The gag-onc fusion protein (also written as Gag-v-Onc, with "v" indicating that the Onc sequence resides in a viral genome) is a general term for a fusion protein formed from a group-specific antigen ('gag') gene and that of an oncogene ('onc'), a gene that plays a role in the development of a cancer.

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Gardasil

Gardasil, also known as Gardisil or Silgard or recombinant human papillomavirus vaccine, is a vaccine for use in the prevention of certain strains of human papillomavirus (HPV), specifically HPV types 6, 11, 16 and 18.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Harald zur Hausen

Harald zur Hausen (born 11 March 1936) is a German virologist and professor emeritus.

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Hepatitis B

Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver.

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Hepatitis B virus

Hepatitis B virus, abbreviated HBV, is a double stranded DNA virus, a species of the genus Orthohepadnavirus, and a member of the Hepadnaviridae family of viruses.

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Hepatitis C

Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver.

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Hepatitis C virus

Hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae.

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Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.

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Hodgkin's lymphoma

Hodgkin's lymphoma (HL) is a type of lymphoma which is generally believed to result from white blood cells of the lymphocyte kind.

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HPV vaccines

Human papilloma virus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus.

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HPV-positive oropharyngeal cancer

Human papillomavirus-positive oropharyngeal cancer (HPV+OPC) is a subtype of oropharyngeal squamous cell carcinomas (OSCC), associated with the human papillomavirus type 16 virus (HPV16).

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Human cytomegalovirus

Human cytomegalovirus is a species of the virus genus Cytomegalovirus, which in turn is a member of the viral family known as Herpesviridae or herpesviruses.

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Human papillomavirus infection

Human papillomavirus infection is an infection by human papillomavirus (HPV).

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Human T-lymphotropic virus

The human T-lymphotropic virus, human T-cell lymphotropic virus, or human T-cell leukemia-lymphoma virus (HTLV) family of viruses are a group of human retroviruses that are known to cause a type of cancer called adult T-cell leukemia/lymphoma and a demyelinating disease called HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).

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Human T-lymphotropic virus 1

Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus type 1 (HTLV-I), also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseases including very aggressive adult T-cell lymphoma (ATL), HTLV-I-associated myelopathy, uveitis, Strongyloides stercoralis hyper-infection and some other diseases.

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International Agency for Research on Cancer

The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.

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Kaposi's sarcoma

Kaposi's sarcoma (KS) is a type of cancer that can form masses in the skin, lymph nodes, or other organs.

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Kaposi's sarcoma-associated herpesvirus

Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is HHV-8.

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Koch's postulates

Koch's postulates are four criteria designed to establish a causative relationship between a microbe and a disease.

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Large tumor antigen

The large tumor antigen (also called the large T-antigen and abbreviated LTag or LT) is a protein encoded in the genomes of polyomaviruses, which are small double-stranded DNA viruses.

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List of infectious diseases

Infectious diseases arranged by name.

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List of National Roads in Latvia

This is a list of National Roads in Latvia.

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Ludwik Gross

Ludwik Gross (September 11, 1904 – July 19, 1999) was a Polish-American virologist who discovered two different tumor viruses, murine leukemia virus and mouse polyomavirus, capable of causing cancers in laboratory mice.

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Malignant transformation

Malignant transformation is the process by which cells acquire the properties of cancer.

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Merkel cell polyomavirus

Merkel cell polyomavirus (MCV or MCPyV) was first described in January 2008 in Pittsburgh, Pennsylvania.

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Merkel-cell carcinoma

Merkel-cell carcinoma (MCC) is a rare and highly aggressive skin cancer, which, in most cases, is caused by the Merkel cell polyomavirus (MCV) discovered by scientists at the University of Pittsburgh in 2008.

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Michael A. Epstein

Sir Michael Anthony Epstein, CBE, FRS, FMedSci (born 18 May 1921) is a British pathologist and academic.

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Michael Houghton (virologist)

Michael Houghton is a British scientist, who along with Qui-Lim Choo, George Kuo and Daniel W. Bradley, co-discovered Hepatitis C in 1989.

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Mouse mammary tumor virus

Mouse mammary tumor virus (MMTV) is a milk-transmitted retrovirus like the HTL viruses, HI viruses, and BLV.

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Mucoepidermoid carcinoma

Mucoepidermoid carcinoma is the most common type of minor salivary gland malignancy in adults.

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Murine polyomavirus

Murine polyomavirus (also known as mouse polyomavirus, Polyomavirus muris, or Mus musculus polyomavirus 1, and in older literature as SE polyoma or parotid tumor virus; abbreviated MPyV) is an unenveloped double-stranded DNA virus of the polyomavirus family.

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Nasopharynx cancer

Nasopharynx cancer or nasopharyngeal carcinoma (NPC) is the most common cancer originating in the nasopharynx, most commonly in the postero-lateral nasopharynx or pharyngeal recess or 'Fossa of Rosenmüller' accounting for 50% cases.

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Oncogene

An oncogene is a gene that has the potential to cause cancer.

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Oncolytic virus

An oncolytic virus is a virus that preferentially infects and kills cancer cells.

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P107

The P107 was a World War II French half-track.

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P53

Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

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Patrick S. Moore

Patrick S. Moore (born October 21, 1956) is an Irish and American virologist and epidemiologist who co-discovered together with his wife, Yuan Chang, two different human viruses causing the AIDS-related cancer Kaposi's sarcoma and the skin cancer Merkel cell carcinoma.

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Penile cancer

Penile cancer is a malignant growth found on the skin or in the tissues of the penis.

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Plasmid

A plasmid is a small DNA molecule within a cell that is physically separated from a chromosomal DNA and can replicate independently.

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Polyomaviridae

Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds.

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Post-transplant lymphoproliferative disorder

Post-transplant lymphoproliferative disorder (PTLD) is the name given to a B-cell proliferation due to therapeutic immunosuppression after organ transplantation.

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Primary effusion lymphoma

Primary effusion lymphoma (PEL) is a B-cell lymphoma, presenting with a malignant effusion without a tumor mass.

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Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

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R. Palmer Beasley

Robert Palmer Beasley (April 29, 1936 – August 25, 2012) was a physician, public health educator and epidemiologist whose work on hepatitis B involved extensive investigations in Taiwan.

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Representational difference analysis

Representational difference analysis (RDA) is a technique used in biological research to find sequence differences in two genomic or cDNA samples.

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Retinoblastoma protein

The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers.

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Retrovirus

A retrovirus is a single-stranded positive-sense RNA virus with a DNA intermediate and, as an obligate parasite, targets a host cell.

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Richard Shope

Richard Edwin Shope (December 25, 1901 – October 2, 1966) was an American virologist who at the Rockefeller Institute identified influenzavirus A in pigs in 1931.

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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RNA virus

An RNA virus is a virus that has RNA (ribonucleic acid) as its genetic material.

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Robert Gallo

Robert Charles Gallo (born March 23, 1937) is an American biomedical researcher.

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Robert Koch

Robert Heinrich Hermann Koch (11 December 1843 – 27 May 1910) was a German physician and microbiologist.

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Rous sarcoma virus

Rous sarcoma virus (RSV) is a retrovirus and is the first oncovirus to have been described: it causes sarcoma in chickens.

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S phase

S phase (synthesis phase) is the part of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase.

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Sarah Stewart (cancer researcher)

Sarah Stewart (August 16, 1905 – November 27, 1976) was a Mexican American researcher who pioneered the field of viral oncology research, the first to show that cancer-causing viruses can spread from animal to animal.

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Shope papilloma virus

The Shope papilloma virus (SPV), also known as cottontail rabbit papilloma virus (CRPV) or Kappapapillomavirus 2, is a papillomavirus which infects certain leporids, causing keratinous carcinomas resembling horns, typically on or near the animal’s head.

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SV40

SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans.

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Transcriptome

The transcriptome is the set of all RNA molecules in one cell or a population of cells.

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UBE3A

Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene.

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Ubiquitin

Ubiquitin is a small (8.5 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e. it occurs ''ubiquitously''.

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University of Pittsburgh Cancer Institute

The University of Pittsburgh Cancer Institute (UPCI) is a National Cancer Institute (NCI)-designated Comprehensive Cancer Center located in the Hillman Cancer Center in the Shadyside neighborhood of Pittsburgh, Pennsylvania, United States.

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Viral hepatitis

Viral hepatitis is liver inflammation due to a viral infection.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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Vulvar cancer

Vulvar cancer is a malignant, invasive growth in the vulva, or the outer portion of the female genitals.

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World Health Organization

The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.

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Yuan Chang

Yuan Chang (born 17 November 1959) is an American virologist and pathologist who co-discovered Kaposi's sarcoma-associated herpesvirus (KSHV) and Merkel cell polyomavirus, two of the seven known human oncoviruses.

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Yvonne Barr

Yvonne Barr (11 March 1932 – 13 February 2016) was a virologist.

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References

[1] https://en.wikipedia.org/wiki/Oncovirus

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