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UGT1A8

Index UGT1A8

UDP-glucuronosyltransferase 1-8 is an enzyme that in humans is encoded by the UGT1A8 gene. [1]

17 relations: Anthraquinone, Bilirubin, C-terminus, Coumarin, Directionality (molecular biology), Enzyme, Exon, Flavones, Gene, Glucuronidation, Glucuronosyltransferase, Lipophilicity, Metabolite, N-terminus, Opioid, Phenol, Steroid.

Anthraquinone

Anthraquinone, also called anthracenedione or dioxoanthracene, is an aromatic organic compound with formula.

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Bilirubin

Bilirubin is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Coumarin

Coumarin (2H-chromen-2-one) is a fragrant organic chemical compound in the benzopyrone chemical class, although it may also be seen as a subclass of lactones.

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Directionality (molecular biology)

Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Exon

An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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Flavones

Flavones (flavus.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Glucuronidation

Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.

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Glucuronosyltransferase

Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a cytosolic glycosyltransferase that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule.

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Lipophilicity

Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Opioid

Opioids are substances that act on opioid receptors to produce morphine-like effects.

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Phenol

Phenol, also known as phenolic acid, is an aromatic organic compound with the molecular formula C6H5OH.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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UGT1A8 (gene).

References

[1] https://en.wikipedia.org/wiki/UGT1A8

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